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A new ultrasonic cavitation approach for the synthesis of zinc ferrite nanocrystals
Manickam Sivakumar,Atsuya Towata,Kyuichi Yasui,Toru Tuziuti and Yasuo Iida,Yasuo Iida 한국물리학회 2006 Current Applied Physics Vol.6 No.3
An ultrasound mediated simple emulsion process has been demonstrated for the synthesis of zinc ferrite nanocrystals using the pre-cursors of zinc and iron acetates and rapeseed oil. Following this technique avoids many of the outstanding problems that normally existin conventional emulsion synthesis. Due to the simplicity of this process, it could also become a valuable starting point for the generationof other mixed and complex ferrites.
( Yasuo Suzuki ),( Mitsuo Iida ),( Hiroaki Ito ),( Isamu Saida ),( Toshifumi Hibi ) 대한장연구학회 2016 Intestinal Research Vol.14 No.1
The therapeutic effect of mesalamine is considered to be dose-dependent; however, no consensus has been reached regarding the optimal doses for individual patients. This study aimed to provide new insight for dose optimization using two doses of pH-dependent release mesalamine for induction of remission of moderately active ulcerative colitis (UC). Methods: In a multicenter, double-blind, randomized study, 110 patients with moderately active UC were assigned to two groups after treatment with a constant dose of mesalamine. Fifty-five patients were treated with a pH-dependent release formulation of 3.6 or 4.8 g/day for 8 weeks. The primary endpoint was a decrease in the UC disease activity index (UCDAI) adjusted by covariates. Results: In the full analysis set (n=110), the mean decrease in UCDAI was 3.1 in the 3.6 g/day group and 3.4 in the 4.8 g/day group (P >0.05). In a subgroup analysis, the effectiveness of the 4.8 g/day dose was greater in particular populations, such as those who had been previously treated with a lower dose of mesalamine and those with more severe disease. The safety was comparable between the two groups. Conclusions: The results suggest that treatment with pH-dependent release mesalamine at either 3.6 or 4.8 g/day was effective and safe for the induction of remission in patients with moderately active UC. However, the patients receiving mesalamine at 2.4 g/day but in whom the therapeutic effect is not sufficient and having more severe symptoms (UCDAI 9.10), benefit from higher doses of mesalamine compared to others. (Intest Res 2016;14:50-59)
AN Sihyoung,IIDA Katuhiro,MORI Yasuo 대한교통학회 1998 大韓交通學會誌 Vol.16 No.1
교통계획의 수립은 사람과 화물의 이동상태에 대한 파악으로부터 시작되며, 화물이동상태를 파악하기 위한 가장 기본적인 데이터는 지역별 발생집중 화물량일 것이다. 이러한 지역별 발생집중 화물량의 추계방법중 추계의 간편성과 경제상황변화의 반영이 용이하다는 점에서, 최근 학자들의 싱당한 주목을 받으며 연구되고 있는 것이 産業聯關分析을 응용한 물류해석방법이다. 그러나 이방법은 대상지역의 산업연관표를 기본 data로 하기때문에 해당지역의 산업연관표의 존재여부에 따라서 그 적용범위가 제한된다. 이러한 문제점을 해결하기 위해서 연구되고 있는 방법이 Nonsurvey법이다. Nonsurvey법은 대지역의 산업연관표로부터 그 지역에 포함된 소지역의 산업연관표를 여러 가지 보조적인 데이터를 이용해서 간접적으로 추계하는 방법이다. 본 연구에서는 이러한 Nonsurvey법의 하나로서, 대지역의 산업연관표와 地域分割된 각 소지역의 산업부문별 생산량만을 이용해서 각 소지역의 발생집중화물량을 추계하는 방법을 제안했다. 그리고 日本의 近畿(긴키, Kinki)地域과 이에 속하는 4부현을 대상으로 본 연구의 방법으로 추계된 移出入量과 실제의 産業聯關表상의 移出入量을 비교 · 분석함으로써 본 연구의 방법에 대한 검증을 실시했다. 본 연구에서 제안한 지역별 발생집중 화물량 추계방법의 특징은 다음과 같다. 첫째 대지역 내 각 소지역간의 移出入量이 分配係數라고 하는 産業聯關表의 행방향의 합에 대한 비율을 사용함으로서 간단히 추계가능하다. 둘째, 추계된 소지역의 産業聯關表는 대지역에 대한 시스템전체의 整合性이 유지된다. 셋째, 分割되는 소지역의 數에 관계없이 각 소지역의 移出入量에 대한 추계가 가능하다.
Kenji Koneri,Yasuo Hirono,Daisuke Fujimoto,Katsuji Sawai,Mitsuhiro Morikawa,Makoto Murakami,Takanori Goi,Atsushi Iida,Kanji Katayama,Akio Yamaguchi 대한위암학회 2013 Journal of gastric cancer Vol.13 No.1
Alpha-fetoprotein–producing gastric cancer is associated with poor prognosis because of frequent liver and lymph node metastasis. We present a case with synchronous liver metastasis who survived for 5 years. A 69-year-old man with upper abdominal pain was referred to our hospital. Gastrointestinal endoscopy revealed a Borrmann II-like tumor in the lower part of the stomach. Computed tomography revealed a tumor in the left lobe of the liver. Serum alpha-fetoprotein levels were markedly increased. We performed distal gastrectomy after administering oral tegafur/gimeracil/oteracil potassium and administered hepatic intra-arterial cisplatin injection. Liver metastasis showed partial response on computed tomography. Despite left hepatic lobectomy, further metastases to the liver and mediastinal lymph nodes became difficult to control. After sorafenib tosylate administration, stabilization of the disease was observed for 4 months. We conclude that hepatic intra-arterial chemotherapy and oral administration of sorafenib tosylate may potentially improve the prognosis in such cases.
Koneri, Kenji,Hirono, Yasuo,Fujimoto, Daisuke,Sawai, Katsuji,Morikawa, Mitsuhiro,Murakami, Makoto,Goi, Takanori,Iida, Atsushi,Katayama, Kanji,Yamaguchi, Akio The Korean Gastric Cancer Association 2013 Journal of gastric cancer Vol.13 No.1
Alpha-fetoprotein-producing gastric cancer is associated with poor prognosis because of frequent liver and lymph node metastasis. We present a case with synchronous liver metastasis who survived for 5 years. A 69-year-old man with upper abdominal pain was referred to our hospital. Gastrointestinal endoscopy revealed a Borrmann II-like tumor in the lower part of the stomach. Computed tomography revealed a tumor in the left lobe of the liver. Serum alpha-fetoprotein levels were markedly increased. We performed distal gastrectomy after administering oral tegafur/gimeracil/oteracil potassium and administered hepatic intra-arterial cisplatin injection. Liver metastasis showed partial response on computed tomography. Despite left hepatic lobectomy, further metastases to the liver and mediastinal lymph nodes became difficult to control. After sorafenib tosylate administration, stabilization of the disease was observed for 4 months. We conclude that hepatic intra-arterial chemotherapy and oral administration of sorafenib tosylate may potentially improve the prognosis in such cases.