http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Yaodong Dong (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
Dong Tianxiu,Jiang Jian,Zhang Hao,Liu Hongyuan,Zou Xiaomeng,Niu Jiamei,Mao Yingxuan,Zhu Mingwei,Chen Xi,Li Zizhuo,Chen Yaodong,Shi Chunying,Yang Xiuhua 나노기술연구협의회 2021 Nano Convergence Vol.8 No.29
Hepatocellular carcinoma (HCC) is one of the most malignant tumors in the world, and patients with HCC face a poor prognosis. The conventional therapeutic strategies for HCC have undergone a challenge-riddled evolution owing to side effects and unsatisfactory efficacy. Here, aiming to provide a new method of HCC elimination, we formulated a novel multifunctional nanocapsule (PFP@PLGA/Cu 12 Sb 4 S 13 , PPCu) with applications in contrast-enhanced ultrasound imaging (CEUS) and photothermal therapy (PTT). These PPCu were successfully constructed with an average diameter of 346 nm (polydispersity index, PDI = 0.276). The reinforced contrast ratio of these PPCu was determined by CEUS, revealing their promising applications in image-guided monitoring of HCC treatment. Furthermore, the excellent photoabsorption and biocompatibility indicated by organ H&E staining indicated that PPCu meet quality expectations for use as photothermal transduction agent (PTA). PPCu treatment at 50 °C and higher temperatures efficiently repressed the proliferation, induced the apoptosis and decreased the motility of HCC cells. These effects might have been results of RAS/MAPK/MT-CO1 signaling pathway inhibition. In summary, PPCu were constructed to integrate CEUS and PTT successfully into therapy, which can lead to HCC elimination through RAS/MAPK/MT-CO1 signaling pathway repression.
-
Research Progress on Non-coding RNAs in Cholesteatoma of the Middle Ear
Dongliang Liu,Hang Zhang,Xiulan Ma,Yaodong Dong 대한이비인후과학회 2023 Clinical and Experimental Otorhinolaryngology Vol.16 No.2
Cholesteatoma of the middle ear is a common disease in otolaryngology that is receiving increasing attention. It is estimat-ed that over five million people around the world have suffered from middle ear cholesteatoma. The annual incidence ofmiddle ear cholesteatoma has been reported to be 9.2 per 100,000 in adults and 3 per 100,000 in children. Without timelydiscovery and intervention, cholesteatomas can become perilously large and damage intratemporal structures, causing vari-ous intracranial and extracranial complications. No practical nonsurgical treatments are currently available. Although multi-ple hypotheses exist, research directions have consistently focused on cell proliferation, apoptosis, and bone destruction. Non-coding RNAs (ncRNAs), especially microRNAs (miRNAs), long ncRNAs (lncRNAs), and circular RNAs (circRNAs),have recently received increasing attention because of their key roles in gene expression, cell cycle regulation, and the de-velopment of many diseases. Although ncRNAs are not involved in protein translation, they are abundant in the genome,with only approximately 2% of genes encoding proteins and the remaining approximately 98% encoding ncRNAs. Thepurpose of this review is to summarize the current state of knowledge regarding the specific role of ncRNAs in middle earcholesteatoma.
-
Yugan He,Qi Yan,Xiaoyu Chang,Meiying Zhu,Weiwei Wang,Menglong Dong,Lianjie Song,Junjiao Yang,Yaodong Huang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.5
A TiO2 photocatalyst with peony-like microstructures and a large percentage of exposed {001} facets was synthesized using a facile solvethermal method. The peony-like TiO2 was obtained using HF as a capping agent, TiCl4 as the precursor and ethanol as the solvothermal agent. The parameters which influence the mophology and formation mechanism of the products including the HF concentration, the reaction time and temperature and the solvothermal solvent, were investigated. The samples were characterized using field emission scanning electron microscopy, transmission electron microscopy, X-ray diffraction and N2 adsorption and desorption analysis. As the reaction time or reaction temperature increased, the morphology TiO2 changed from hexagonally assembled microspheres to peony-like microflowers which were composed of stacks of ultrathin nanosheets. The other reaction parameters also play a crucial role in the formation of the TiO2 microstuctures. Photocatalytic experiments showed that the synthesized TiO2 out-performed Degussa P25 in the photodegradation of methelene blue under a very weak UV light irradiation (power: 8 W, light intensity: 0.4mW cm -1).
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
