Stabilization of Target Tracking with 3-axis Motion Compensation for Camera System on Flying Vehicle

Sun, Yanjie,Jeon, Dongwoon,Kim, Doo-Hyun Institute of Embedded Engineering of Korea 2014 대한임베디드공학회논문지 Vol.9 No.1

This paper presents a tracking system using images captured from a camera on a moving platform. A camera on an unmanned flying vehicle generally moves and shakes due to external factors such as wind and the ego-motion of the machine itself. This makes it difficult to track a target properly, and sometimes the target cannot be kept in view of the camera. To deal with this problem, we propose a new system for stable tracking of a target under such conditions. The tracking system includes target tracking and 3-axis camera motion compensation. At the same time, we consider the simulation of the motion of flying vehicles for efficient and safe testing. With 3-axis motion compensation, our experimental results show that robustness and stability are improved.

Output Feedback Stabilization for a Class of Cascade Nonlinear ODEPDE Systems

Yanjie Chang,Tongjun Sun,Xianfu Zhang,Xiandong Chen 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.7

In this paper, the output feedback stabilization problem is studied for a class of cascade nonlinear ODEPDE systems. The nonlinear terms of ODE-subsystem are assumed to be bounded by a known constant multiplied by unmeasured states, and PDE-subsystem is a diffusion equation. Especially, the unstable diffusion equation is considered. Based on the low gain observer and a series of transformations, the output feedback stabilization problem is converted into designing proper gain parameters. Furthermore, the stability of the closed-loop system is analyzed by Lyapunov theorem. Finally, two numerical examples are given to demonstrate the effectiveness of the proposed control strategy.

Anti-neuroinflammatory Activity of Nobiletin on Suppression of Microglial Activation

Cui, Yanji,Wu, Jinji,Jung, Sung-Cherl,Park, Deok-Bae,Maeng, Young-Hee,Hong, Jeong Yun,Kim, Se-Jae,Lee, Sun-Ryung,Kim, Soon-Jong,Kim, Sang Jeong,Eun, Su-Yong Pharmaceutical Society of Japan 2010 BIOLOGICAL & PHARMACEUTICAL BULLETIN Vol.33 No.11

<P>A growing body of evidence suggests that nobiletin (5,6,7,8,3′,4′-hexamethoxy flavone) from the peel of citrus fruits, enhances the damaged cognitive function in disease animal models. However, the neuroprotective mechanism has not been clearly elucidated. Since nobiletin has shown anti-inflammatory effects in several tissues, we investigated whether nobiletin suppresses excessive microglial activation implicated in neurotoxicity in lipopolysaccharide (LPS)-stimulated BV-2 microglia cell culture models. Release of nitric oxide (NO), the major inflammatory mediator in microglia, was markedly suppressed in a dose-dependent manner following nobiletin treatment (1—50 μ<SMALL>M</SMALL>) in LPS-stimulated BV-2 microglia cells. The inhibitory effect of nobiletin was similar to that of minocycline, a well-known microglial inactivator. Nobiletin significantly inhibited the release of the pro-inflammatory cytokine tumor necrosis factor (TNF-α) and interleukin-1β (IL-1β). LPS-induced phosphorylations of extracellular signal-regulated kinase (ERK), c-Jun NH<SUB>2</SUB>-terminal kinase (JNK), and p38 mitogen-activated protein kinases (MAPKs) were also significantly inhibited by nobiletin treatment. In addition, nobiletin markedly inhibited the LPS-induced pro-inflammatory transcription factor nuclear factor κB (NF-κB) signaling pathway by suppressing nuclear NF-κB translocation from the cytoplasm and subsequent expression of NF-κB in the nucleus. Taken together, these results may contribute to further exploration of the therapeutic potential and molecular mechanism of nobiletin in relation to neuroinflammation and neurodegenerative diseases.</P>

Ethnic Networking in the Transnational Engagement of Chinese American Scientists

Xiao-e Sun,Yanjie Bian 경남대학교 극동문제연구소 2012 ASIAN PERSPECTIVE Vol.36 No.3

This study, based on in-depth interviews, applies a social-network approach to examining the important role that ethnic networking has played in promoting the transnational engagement of Chinese American scientists in China’s science sector and in higher education. The study finds that the transnational involvement of Chinese American scientists is facilitated by both their strong and weak ethnic ties: strong ties provide connection and rapport, while weak ties facilitate access to position and resources.

Multiple Circles Detection in Complex Scenes

Chu Guangli,Wang Yanjie,Sun Honghai,Fan Bo,Wen Zhuoman 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.1

To solve the problem that the conventional circle detection algorithm has low processing speed and poor identification accuracy in presence of overlap of objects, a novel multiple circles detection algorithm is proposed. Firstly, the consecutive edges with single pixel are obtained through an edge tracking method. Moreover, the edges of overlaid objects are extracted from the cross section according to the linear projection method. Secondly, a large number of non-circular edges are excluded by utilizing a coarse detection that decides whether four points on an edge are on the same circle or not. Lastly, the circles are recognized by the fine detection according to the geometrical feature which two subarcs belonging to one circle have the same center and radius. The experimental results demonstrate that the algorithm is superior in speed, precision and accuracy, comparing to the conventional ones, such as Hough transform circle detection and randomized circle detection. Furthermore, it can solve the issues from overlap of objects and accurately identify the multiple circular objects in the complex scenes as well. The algorithm is concise, fast and robust.

Effects of Nicotine on Aβ or CT_(105)-induced Toxicity

Seo, Ji-Heui,Chang, Keun-A,Kim, Hye-Sun,Park, Cheol Hyoung,Kim, Seong Han,Lee, Me Jeong,Jeong, Sung-Jin,Choi, Se Hoon,Rah, Jong-Cheol,Koo, Jawook,Kim, Eun-Mee,Xu, Yanji,--,Choi, Jun Ho,Shin, Jae Kyung 한국뇌학회 2001 한국뇌학회지 Vol.1 No.1

알츠하이머 치매의 병인기전에서 아밀로이드 베타 펩티드는 중요한 역할을 할 것이라는 연구결과가 많이 보고되어있다. 그러나 알츠하이머 치매의 진행과 아밀로이드 베타 펩티드의 생성에는 여러 가지 모순도 보고되었다. 그러므로 아밀로이드 전구단백질에서 생성된 아밀로이드 베타 펩티드 외에 여러 가지 대사물들이 알츠하이머 치매의 병인기전과 관련이 있으리라 여겨진다. 이미 본 연구팀은 니코틴이 신경보호효과가 있다고 알려진 분비형 아밀로이드 전구단백질의 발현을 시간, 농도 의존적으로 증가시킨다는 연구결과를 보고하였다. 이번 논문에서는 니코틴의 전처리로 아밀로이드 베타 펩티드 및 아밀로이드 C단 단백질에 의한 1차 신경세포에서의 세포독성 효과가 억제되며, 이러한 효과는 니코틴의 길항제인 알파붕가로톡신에 의해 상쇄된다는 연구결과를 얻었다. 뿐만 아니라 C단 단백질을 PC12세포에 유전자를 이입시켰을 때, 니코틴에 의하며 세포 독성이 억제되는 결과를 얻었다. 이러한 연구결과로 볼 때, 니코틴이나 니코틴 수용체는 콜린성 신경전달 물질 보상 뿐만 아니라 아밀로이드 베타 펩티드, 아밀로이드 C단 단백질의 독성을 저해함으로써 인지기능 향상에 영향을 줄 것으로 예상된다. Several lines of evidence indicate that Aβ may play an important role in the pathogenesis of AD. However, there are several discrepancies between the production of Aβ and the development of the disease. Thus, Aβ may not be the sole active fragment of β-amyloid precursor protein (βAPP) in the neurotoxicity associated with AD. Previously, findings from our experiments have shown that nicotine enhances the release of APPs, which has neurotrophic and neuroprotective activities in concentration and time-dependent manners. In this study, our results showed that Pretreatment of nicotine (>10μM, for 24hr) partially prevented Aβ or CT_(105)-induced cytotoxicity in primary cultured neuronal cells, and the effects of nicotine-induced protection was inhibited by the pretreatment with a nicotine receptor antagonist α-bungarotoxin. Nicotine (>10μM, for 24hr) partially inhibited CT_(105)-induced cytotoxicity when PC12 cells was transfected with CT_(105). From these results, we proposed that treatment of nicotine or nicotinic receptor agonist might improve the cognitive functions not only by supplementation of cholinergic neurotransmission but also by protecting Aβ-or CT_(105)-induced neurotoxicity probably through the increased release of APPs and the activation of nicotinic receptor.

Research on Machining Deformation of 7050 Aluminum Alloy Aircraft Rib Forging

Yaoqiong Liu,Hai Gong,Yongbiao He,Tao Zhang,Yanjie Sun,Xiaolong Liu 한국정밀공학회 2022 International Journal of Precision Engineering and Vol.23 No.5

T-type rib strip was the key connective component between the fuselage and wing of the aircraft and the main processes for preparation of T-type rib strip consisted of forging forming, solution quenching, cold pressing and machining. The variation of residual stress and its effect on the deformation during the final machining process was quite complex. In this study, the numerical models of solution quenching, cold pressing and machining of T-type rib strip was established. The variation of residual stress on the deformation of T-type rib strip was studied. The results show that the maximum quenching stress of the T-type rib was about − 200 MPa at the surface and 150 MPa in the core. A reduction of 60% of the average residual stress can be achieved during the cold pressing process with a reduction rate of 3% and a friction coefficient of 0.3. Compared with direct machining after quenching, the deformation of machining after solution quenching and cold pressing was greatly reduced and the reduction rate reached 65.04%.

Construction of graphene/AuNPs based amperometric immunosensor for detecting bladder cancer biomarker apolipoprotein A1

Jing Yang,Wang Xingyuan,Zhou Tingting,Wei Liangjun,Guo Meiling,Liu Yanan,Sun Xiaoqi,Wang Yanjie 한국탄소학회 2024 Carbon Letters Vol.34 No.3

This paper presents the construction and characterization of an amperometric immunosensor based on the graphene/gold nanoparticles (AuNPs/GO) nanocomposite for the detection of the bladder cancer biomarker, apolipoprotein A1 (Apo-A1). The morphological analysis of the AuNPs/GO nanocomposite demonstrated an almost spherical shape of AuNPs and the successful coverage of their surface by graphene oxide. An increased G peak and decreased D peak after the association of AuNPs with GO, implied a reduction in graphene defects. The X-ray photoelectron spectroscopy (XPS) indicated a significant decrease in the quantity of oxygen-containing functional groups in the AuNPs/GO nanocomposite, as compared to the original GO. Furthermore, the developed sensor demonstrated commendable sensitivity and selectivity, with a wide linear range for Apo-A1 detection. Importantly, the immunosensor exhibited remarkable stability over a period of 14 days, signifying its potential for practical applications.

Identification of quantitative trait loci associated with drought tolerance traits in rice (Oryza sativa L.) under PEG and field drought stress

Han, Bing,Wang, Jiao,Li, Yafei,Ma, Xiaoding,Jo, Sumin,Cui, Di,Wang, Yanjie,Park, Dongsoo,Song, Youchun,Cao, Guilan,Wang, Xingsheng,Sun, Jianchang,Shin, Dongjin,Han, Longzhi Springer Netherlands 2018 Euphytica Vol.214 No.4

YAP1 inhibits the senescence of alveolar epithelial cells by targeting Prdx3 to alleviate pulmonary fibrosis

Su Wei,Guo Yingying,Wang Qianqian,Ma Lu,Zhang Qing,Zhang Yuhan,Geng Yiding,Jin Tongzhu,Guo Jiayu,Yang Ruoxuan,Niu Zhihui,Ren Lingxue,Wang Yanjie,Ning Zhiwei,Li Wenyue,He Wenxin,Sun Jian,Li Tianyu,Li Z 생화학분자생물학회 2024 Experimental and molecular medicine Vol.56 No.-

The senescence of alveolar type II (AT2) cells impedes self-repair of the lung epithelium and contributes to lung injury in the setting of idiopathic pulmonary fibrosis (IPF). Yes-associated protein 1 (YAP1) is essential for cell growth and organ development; however, the role of YAP1 in AT2 cells during pulmonary fibrosis is still unclear. YAP1 expression was found to be downregulated in the AT2 cells of PF patients. Deletion of YAP1 in AT2 cells resulted in lung injury, exacerbated extracellular matrix (ECM) deposition, and worsened lung function. In contrast, overexpression of YAP1 in AT2 cells promoted alveolar regeneration, mitigated pulmonary fibrosis, and improved lung function. In addition, overexpression of YAP1 alleviated bleomycin (BLM) -induced senescence of alveolar epithelial cells both in vivo and in vitro. Moreover, YAP1 promoted the expression of peroxiredoxin 3 (Prdx3) by directly interacting with TEAD1. Forced expression of Prdx3 inhibited senescence and improved mitochondrial dysfunction in BLM-treated MLE-12 cells, whereas depletion of Prdx3 partially abrogated the protective effect of YAP1. Furthermore, overexpression of Prdx3 facilitated self-repair of the injured lung and reduced ECM deposition, while silencing Prdx3 attenuated the antifibrotic effect of YAP1. In conclusion, this study demonstrated that YAP1 alleviates lung injury and pulmonary fibrosis by regulating Prdx3 expression to improve mitochondrial dysfunction and block senescence in AT2 cells, revealing a potential novel therapeutic strategy for pulmonary fibrosis.