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- 저자 : Yang Dehong (검색결과 6 건)
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Urinary Biomarkers for the Noninvasive Detection of Gastric Cancer
Li, Dehong,Yan, Li,Lin, Fugui,Yuan, Xiumei,Yang, Xingwen,Yang, Xiaoyan,Wei, Lianhua,Yang, Yang,Lu, Yan The Korean Gastric Cancer Association 2022 Journal of gastric cancer Vol.22 No.-
Gastric cancer (GC) is associated with high morbidity and mortality rates. Thus, early diagnosis is important to improve disease prognosis. Endoscopic assessment represents the most reliable imaging method for GC diagnosis; however, it is semi-invasive and costly and heavily depends on the skills of the endoscopist, which limit its clinical applicability. Therefore, the search for new sensitive biomarkers for the early detection of GC using noninvasive sampling collection methods has attracted much attention among scientists. Urine is considered an ideal biofluid, as it is readily accessible, less complex, and relatively stable than plasma and serum. Over the years, substantial progress has been made in screening for potential urinary biomarkers for GC. This review explores the possible applications and limitations of urinary biomarkers in GC detection and diagnosis.
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Urinary Biomarkers for the Noninvasive Detection of Gastric Cancer
Li Dehong,Yan Li,Lin Fugui,Yuan Xiumei,Yang Xingwen,Yang Xiaoyan,Wei Lianhua,Yang Yang,Lu Yan 대한위암학회 2022 Journal of gastric cancer Vol.22 No.4
Gastric cancer (GC) is associated with high morbidity and mortality rates. Thus, early diagnosis is important to improve disease prognosis. Endoscopic assessment represents the most reliable imaging method for GC diagnosis; however, it is semi-invasive and costly and heavily depends on the skills of the endoscopist, which limit its clinical applicability. Therefore, the search for new sensitive biomarkers for the early detection of GC using noninvasive sampling collection methods has attracted much attention among scientists. Urine is considered an ideal biofluid, as it is readily accessible, less complex, and relatively stable than plasma and serum. Over the years, substantial progress has been made in screening for potential urinary biomarkers for GC. This review explores the possible applications and limitations of urinary biomarkers in GC detection and diagnosis.
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Existence and multiplicity of positive solutions for multipoint boundary value problems
Dehong Ji,Yitao Yang,Weigao Ge 한국전산응용수학회 2009 Journal of applied mathematics & informatics Vol.27 No.1
This paper deals with the multipoint boundary value problem for one dimensional p-Laplacian (φp(u‘))’(t) + f(t, u(t)) = 0, t ∈ (0, 1), subject to the boundary value conditions: <수식>,<수식> Using a fixed point theorem for operators on a cone, we provide sufficient conditions for the existence of multiple (at least three) positive solutions to the above boundary value problem. This paper deals with the multipoint boundary value problem for one dimensional p-Laplacian (φp(u‘))’(t) + f(t, u(t)) = 0, t ∈ (0, 1), subject to the boundary value conditions: <수식>,<수식> Using a fixed point theorem for operators on a cone, we provide sufficient conditions for the existence of multiple (at least three) positive solutions to the above boundary value problem.
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Similarity-Based Fast Open-Circuit Fault Diagnosis Method for Modular Multilevel Converters
Dehong Zhou,Huan Qiu,Shunfeng Yang,Yi Tang 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5
Fault diagnosis is indispensable for the reliable operation of modular multilevel converters (MMCs). This paper presents a submodule voltage similarity-based, real-time and fast open-circuit fault diagnosis method for MMCs. The proposed fault detection and location (FDL) method is derived based on the similarity analysis of capacitor voltages under both normal and fault conditions. Due to the absence of the discharging current path caused by the open-circuit fault, capacitor voltage of the submodule with the faulty switch will differ from those with healthy switches. This characteristic can be extracted by designing the correlation coefficients of the capacitor voltages at the same arm. With the help of correlation coefficients, the opencircuit fault can be located at the early stage before the capacitor voltage is charged very high. All the data required for the proposed FDL method can be obtained by the available sampled data for the control scheme of MMCs. No extra measurement or hardware is required. Experimental results validate that the proposed FDL method can detect and locate the open-circuit fault rapidly and accurately within one fundamental period.
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EXISTENCE AND MULTIPLICITY OF POSITIVE SOLUTIONS FOR MULTIPOINT BOUNDARY VALUE PROBLEMS
Ji, Dehong,Yang, Yitao,Ge, Weigao The Korean Society for Computational and Applied M 2009 Journal of applied mathematics & informatics Vol.27 No.1
This paper deals with the multipoint boundary value problem for one dimensional p-Laplacian $({\phi}_p(u'))'(t)$ + f(t,u(t)) = 0, $t{\in}$ (0, 1), subject to the boundary value conditions: u'(0) - $\sum\limits^n_{i=1}{\alpha_i}u({\xi}_i)$ = 0, u'(1) + $\sum\limits^n_{i=1}{\alpha_i}u({\eta}_i)$ = 0. Using a fixed point theorem for operators on a cone, we provide sufficient conditions for the existence of multiple (at least three) positive solutions to the above boundary value problem.
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Comparative genomic analysis of Mycoplasma anatis strains
Zhou Qi,Mai Kaijie,Yang Dehong,Liu Junfa,Yan Zhuanqiang,Luo Cuifen,Tan Yangtong,Cao Sheng,Zhou Qingfeng,Chen Li,Chen Feng 한국유전학회 2021 Genes & Genomics Vol.43 No.11
Background The Gram-negative intracellular bacterium Mycoplasma anatis is a pathogen of respiratory infectious diseases in ducks and has caused signifcant economic losses in the poultry industry. Objective This study, as the frst report of the structure and function of the pan-genome of Mycoplasma anatis, may provide a valuable genetic basis for many aspects of future research on the pathogens of waterfowl. Methods We sequenced the whole genomes of 15 Mycoplasma anatis isolated from ducks in China. Draft genome sequencing was carried out and whole-genome sequencing was performed by the sequencers of the PacBio Sequel and an IonTorrent Personal Genome Machine (PGM). Then the common genic elements of protein-coding genes, tRNAs, and rRNAs of Mycoplasma anatis genomes were predicted by using the pipeline Prokka v1.13.7. To investigate homologous protein clusters across Mycoplasma anatis genomes, we adopted Roary v3.13.0 to cluster orthologous genes (OGs) based on the following criteria. Results We obtained one complete genome and 14 genome sketches. Microbial mobile genetic element analysis revealed the distribution of insertion sequences (IS30, IS3, and IS1634), prophage regions, and CRISPR arrays in the genome of Mycoplasma anatis. Comparative genomic analysis decoded the genetic components and functional classifcation of the pan-genome of Mycoplasma anatis that comprised 646 core genes, 231 dispensable genes and among them 110 was strainspecifc. Virulence-related gene profles of Mycoplasma anatis were systematically identifed, and the products of these genes included bacterial ABC transporter systems, iron transport proteins, toxins, and secretion systems. Conclusion A complete virulence-related gene profle of Mycoplasma anatis has been identifed, most of the genes are highly conserved in all strains. Sequencing results are relevant to the molecular mechanisms of drug resistance, adaptive evolution of pathogens, population structure, and vaccine development.
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