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Experimental Study on Dynamic Water Grouting of Modified Water-Soluble Polyurethane
Xiaofan Liu,Junguang Wang,Kun Huang,Fengyun Li 대한토목학회 2019 KSCE Journal of Civil Engineering Vol.23 No.9
In underground project, water inrush disaster often occurs, resulting in a large number of casualties and economic losses. To solve these problems, grouting is one of the main techniques for controlling water inrush. At present, the research results on the treatment of water inrush by grouting are based on anhydrous or hydrostatic grouting. However, the study of dynamic water grouting is relatively few and the grouting materials are a little bit. In this paper, water-soluble polyurethane was selected as grouting material, modified by adding hydroxypropyl methyl cellulose, and the bond strength and microstructure change before and after modification are studied via bond strength experiment and microscopic observation. In addition, the WPU (water-soluble polyurethane) diffusion regularity of dynamic water grouting is studied by indoor flat grouting test. The research also adopts the Bingham fluid model according to the slurry characteristics to derive the grouting diffusion radius. The results show that the compactness of HPMC (hydroxypropyl methyl cellulose)-WPU is improved, the heterogeneity is reduced by 50.4%, and the bonding strength is increased by 153%. Therefore, the anti-scour ability of the HPMC-WPU is enhanced. The deviation of the WPU in the X-axis diffusion radius is 7.7 cm, and the HPMC-WPU is 4.39 cm. What’s more, the formula of grouting diffusion radius is derived. By comparing the formula with experiment results, the deviation is less than 15%, therefore, the formula has the significance of guiding engineering practice.
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Liu Qinghua,Xiong Guojiang,Fu Xiaofan,Mohamed Ali Wagdy,Zhang Jing,Al-Betar Mohammed Azmi,Chen Hao,Chen Jun,Xu Sheng 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.2
Economic dispatch (ED) of thermal power units is significant for optimal generation operation efficiency of power systems. It is a typical nonconvex and nonlinear optimization problem with many local extrema when considering the valve-point effects, especially for large-scale systems. Considering that differential evolution (DE) is efficient in locating global optimal region, while gain-sharing knowledge-based algorithm (GSK) is effective in refining local solutions, this study presents a new hybrid method, namely GSK-DE, to integrate the advantages of both algorithms for solving large-scale ED problems. We design a dual-population evolution framework in which the population is randomly divided into two equal subpopulations in each iteration. One subpopulation performs GSK, while the other executes DE. Then, the updated individuals of these two subpopulations are combined to generate a new population. In such a manner, the exploration and the exploitation are harmonized well to improve the searching efficiency. The proposed GSK-DE is applied to six ED cases, including 15, 38, 40, 110, 120, and 330 units. Simulation results demonstrate that GSK-DE gives full play to the superiorities of GSK and DE effectively. It possesses a quicker global convergence rate to obtain higher quality dispatch schemes with greater robustness. Moreover, the effect of population size is also examined.
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Modeling of SACK-based Fast Retransmission and Recovery
Zhiming Wang,Xiaoping Zeng,Xiaofan Jia,Xue Liu,Li Chen 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.6
Selective acknowledgment (SACK)-based retransmission and recovery mechanism has been implemented in most of current transmission control protocol (TCP) stacks. A new SACK-based loss recovery algorithm is defined in RFC6675 under standard track. Existing models in literatures on modeling TCP SACK, which usually use SACK-based retransmission and recovery mechanism, is no longer accurate for two reasons: 1) they ignore transmission of new packets before retransmission of the last loss; 2) they are based on the strategy that pipe is decreased by 2 upon receipt of a partial ACK, where pipe is the estimated number of outstanding packets. This paper develops a new method to derive the expected number of new packets transmitted between retransmission of the first loss and the last, proposes a model that estimates the expected number of packets transmitted during fast retransmission and recovery phase (FRR) and the corresponding expected duration based on RFC6675. The numerical results show that the proposed model can accurately estimate the expected number of packets transmitted during FRR and the corresponding expected duration based on RFC6675.
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Yang Lu,Shuxin Liu,Shujia Zhang,Guangyan Cai,Hongwei Jiang,Huabin Su,Xiaofan Li,Quan Hong,Xueguang Zhang,Xiangmei Chen 한국분자세포생물학회 2011 Molecules and cells Vol.31 No.3
Tissue inhibitor of metalloproteinase-1 (TIMP-1) plays various roles in cell growth in different cell types. However, few studies have focused on TIMP-1’s effect on fibroblast cells. In this study, we investigated the effects of TIMP-1 overexpression on NIH3T3 fibroblast proliferation and potential transduction signaling pathways involved. Overexpression of TIMP-1, by transfection of the pLenti6/ V5-DESTTIMP-1 plasmid, significantly promoted NIH3T3 proliferation as determined by the BrdU array. Neither 5 nor 15 nM GM6001 (matrix metalloproteinase system inhibitor) affected NIH3T3 proliferation, but 45 nM GM6001 inhibited proliferation. TIMP-1 overexpression activated the p-Akt pathway, but not the p-ERK or p-p38 pathway. In TIMP-1-transfected cells, cyclinD1 was upregulated and p21CIP1 and p27^(KIP1) were downregulated, which promoted cell entry into the S and G2/M phases. The PI3-K inhibitor LY294002 abolished the TIMP-1-induced effects. Overexpression of intracellular TIMP-1 stimulated NIH3T3 fibroblast proliferation in a matrix metalloproteinase (MMP)-independent manner by activating the p-Akt pathway and related cell cycle progression.
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Sun Xin,Luo Xiaochao,Li Ling,Ma Bin,Yao Minghong,Liu Jiali,Ge Long,Chen Xiaofan,Wu Xi,Deng Hongyong,Zhou Xu,Wen Zehuai,Li Guowei,Li Qianrui 한국한의학연구원 2022 Integrative Medicine Research Vol.11 No.3
Rapid recommendation is a novel methodological framework for developing clinical practice guidelines and this framework shares the basic features of classical guidelines but differs from classical clinical practice guidelines in its ‘rapid’ development process (typically within 90 days) with an aim of translat-ing practice-changing studies to recommendations. A recent global innovation of guideline development methodology is the proposal of a rapid recommendation framework for Traditional Chinese Medicine (TCM), which has the potential to add value to the translation of evidence to practice for TCM inter- ventions. Up to now, more than 180 rapid recommendations have been published, but none of them is pertaining to TCM interventions. Due to the nature of multi-dimensional evidence sources for TCM inter- ventions, including classical randomized controlled trials and real world evidence, a more sophisticated methodological approach to synthesize and evaluate the totality of evidence about effects of TCM in- terventions is required. Therefore, appropriate modification to the rapid recommendation framework is necessary. In the efforts to respond to these needs, we have proposed a specific approach to developing rapid recommendations for TCM interventions the Multi-dimensional Evidence Synthesis, Evaluation and Recommendations for TCM interventions (MESERT)
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