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Fuzzy Resilient Energy-to-Peak Filtering for Continuous-Time Nonlinear Systems
Chang, Xiao-Heng,Park, Ju H.,Shi, Peng Institute of Electrical and Electronics Engineers, 2017 IEEE Transactions on Fuzzy Systems Vol. No.
<P>The problem of resilient energy-to-peak filtering for a class of uncertain continuous-time nonlinear systems is investigated in this paper. A Takagi–Sugeno fuzzy model with norm-bounded uncertainties is used to represent the nonlinear plant. Attention is focused on the design of an energy-to-peak filter such that the filtering error system is asymptotically stable and the prescribed energy-to-peak filtering performance is guaranteed, where the designed filter is assumed to have additive gain variations. The proposed design is aimed at all filter matrices with gain variations, which improves the existing results on resilient energy-to-peak filtering for continuous-time systems. A simulation example is provided to show the effectiveness of the proposed methods.</P>
Association Between the Ku70-1310C/G Promoter Polymorphism and Cancer Risk: a Meta-analysis
Xu, Lu,Ju, Xiao-Bing,Li, Pu,Wang, Jue,Shi, Zhu-Mei,Zheng, Ming-Jie,Xue, Dan-Dan,Xu, Yan-Jie,Yin, Yong-Mei,Wang, Shui,You, Yong-Ping Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2
Ku70 plays an important role in DNA double-strand break repair. Studies revealing conflicting results on the role of the Ku70-1310C/G promoter polymorphism on cancer risk led us to perform a meta-analysis to investigate this relationship. Ten case-control studies with 2566 cases and 3058 controls were identified. Odds ratios (ORs) and 95% confidence intervals (CIs) were used to assess the strength of associations. The overall results suggested no association between the Ku70-1310C/G promoter polymorphism and total cancer risk. However, on stratified analysis, significantly increased risks were observed among the Asian population (GG vs. CC: OR=1.50, 95%CI=1.10-2.06; GG vs. CC/CG: OR=1.47, 95%CI=1.07-2.01) and population-based case-control studies (GG vs. CC: OR=1.57, 95%CI=1.12-2.22; CG vs. CC: OR=1.35, 95%CI=1.11-1.64; CG/GG vs. CC: OR=1.37, 95%CI=1.14-1.65). Additionally, variant genotypes were associated with a significantly increased breast cancer risk (GG vs. CC: OR=1.80, 95%CI=1.26-2.56; GG vs. CC/CG: OR=1.40, 95%CI=1.01-1.95).
Chromatographic Behavior of Proteins on Stationary Phase with Aminocarboxy Ligand
Li, Rong,Ju, Ming-Yang,Chen, Bin,Sun, Qing-Yuan,Chen, Guo-Liang,Shi, Mei,Wang, Xiao-Gang,Zheng, Jian-Bin Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.2
An aminocarboxy aspartic acid-bonded silica (Asp-Silica) stationary phase was synthesized using L-aspartic acid as ligand and silica gel as matrix. The standard protein mixtures were separated with prepared chromatographic column. The effects of solution pH, salt concentration and metal ion on the retention of proteins were examined, and also compared with traditional iminodiacetic acid-bonded silica (IDA-Silica) column. The results show that Asp-Silica column exhibited an excellent separation performance for proteins. The retention of proteins on Asp-Silica stationary phase was consistent with electrostatic characteristic of cation-exchange. The stationary phase displayed typical metal chelate property after fixing copper ion (II) on Asp-Silica. Under competitive eluting condition, protein mixtures were effectively isolated. Asp ligand showed better ion-exchange and metal chelating properties as compared with IDA ligand.
Feng-Xue Jin,Xiao-Bo Xie,Shi-Dong Ji,Hong-Guang Ju,Jung-Pil Suh,Hung-Goo Hwang,Sang-Nag Ahn 한국작물학회 2008 한국작물학회 학술발표대회 논문집 Vol.2008 No.10
Grain weight (GW) or grain size is the most important target not only as a major component of grain yield, but also associated with the cooking quality in rice breeding program. In a previous study, two loci for grain weight, gw8 and gw9, have been fine map to about 306.4kb and 37.4kb, respectively, in backcross populations derived from a cross between the Korean japonica cultivar Hwaseongbyeo and Oryza rufipigon (IRGC 105491). Both O.rufipogon alleles increased GW in the Hwaseongbyeo background despite the fact that O. rufipogon was the small-seeded parent. To test the effect of pyramiding the QTLs for grain weight, an F2 population consisted of 226 individuals was developed derived from the cross between the two QTLs (gw8 and gw9), and used MAS to select nearly isgenic lines for two QTLs and a pyramiding line. Molecular genotyping of F2 population revealed the existence of interaction between gw8 and gw9. Moreover, the interaction was also confirmed by phenotypic analysis of four QTL-NILs. The results suggest that epistasis interaction is important genetic basis in determining yield traits in rice.
Jin, Feng-Xue,Ji, Shi-Dong,Xie, Xiao-Bo,Kang, Ju-Won,Ju, Hong-Guang,Ahn, Sang-Nag Japanese Society of Breeding 2011 Breeding science Vol.61 No.1
<P>Grain weight (GW) is one of the most important targets for grain yield in rice breeding. In previous studies, two quantitative trait loci (QTLs) for GW, <I>gw8.1</I> and <I>gw9.1</I>, have been identified using progeny derived from a cross between the <I>japonica</I> cultivar Hwaseong and <I>Oryza rufipogon </I>(IRGC 105491). To test whether these quantitative trait loci (QTLs) have an epistatic interaction, we developed an F<SUB>2</SUB> population by crossing two nearly isogenic lines (NILs) harboring <I>gw8.1</I> and <I>gw9.1</I>. Simple sequence repeat (SSR) markers tightly linked to the QTLs were used to select F<SUB>3</SUB> QTL-NILs from the F<SUB>2</SUB> population. A two-way ANOVA revealed an epistatic interaction between the two QTLs in the F<SUB>2</SUB> population (<I>P</I> = 0.0084). This interaction was confirmed by an analysis of F<SUB>3</SUB> QTL-NILs indicating that both QTLs are involved in the same genetic mechanism controlling GW. The <I>gw8.1</I> QTL was further mapped between two SSR markers, RM23204 and RM23211, which are 110.1 kb apart. To our knowledge, this is the first report using QTL-NILs to reveal an epistatic interaction between QTLs for GW.</P>
Chromatographic Behavior of Proteins on Stationary Phase with Aminocarboxy Ligand
Rong Li,Ming-Yang Ju,Bin Chen,Qing-Yuan Sun,Guo-Liang Chen,Mei Shi,Xiao-Gang Wang,Jian-Bin Zheng 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.2
An aminocarboxy aspartic acid-bonded silica (Asp-Silica) stationary phase was synthesized using L-aspartic acid as ligand and silica gel as matrix. The standard protein mixtures were separated with prepared chromatographic column. The effects of solution pH, salt concentration and metal ion on the retention of proteins were examined, and also compared with traditional iminodiacetic acid-bonded silica (IDA-Silica) column. The results show that Asp-Silica column exhibited an excellent separation performance for proteins. The retention of proteins on Asp-Silica stationary phase was consistent with electrostatic characteristic of cation-exchange. The stationary phase displayed typical metal chelate property after fixing copper ion (II) on Asp-Silica. Under competitive eluting condition, protein mixtures were effectively isolated. Asp ligand showed better ion-exchange and metal chelating properties as compared with IDA ligand.
Structure and bioactivity of triterpenoids from the stems of Schisandra sphenanthera
Cheng-Qin Liang,Rong-Hua Luo,Ju-Ming Yan,Yan Li,Xiao-Nian Li,Yi-Ming Shi,Shan-Zhai Shang,Zhong-Hua Gao,Liu-Meng Yang,Yong-Tang Zheng,Wei-Lie Xiao,Hong-Bin Zhang,Han Dong Sun 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.2
Two new triterpenoids, schisphendilactoneA and B (1 and 2), together with three known triterpenoids,were isolated from the stems of Schisandra sphenanthera. Their structures were elucidated by spectroscopic methods,and the absolute configuration of 1 was determined bysingle-crystal X-ray diffraction. Compound 2 showedmoderate inhibitory activity against SW480 cancer cellline, and compound 5 exhibited promising anti-HIV-1activity with EC50 value of 0.52 lg ml-1 and therapeuticindex value of 117.12.
Wei Qiu,Guo-Yue Lv,Chao Jiang,Ping Zhang,Xiao-Dong Sun,Xiao-Ju Shi,Xue-Yan Liu,Guang-Yi Wang 한국간담췌외과학회 2016 한국간담췌외과학회지 Vol.20 No.1
Acute graft-versus-host disease (GVHD) following liver transplantation is a rare but fatal complication. The correct diagnosis and management of GVHD after liver transplantation are still major challenges. Herein, we reported successful salvage treatment of acute GVHD by withdrawal of immunosuppression in a patient who presented with fever, skin rashes, and decreased blood cell counts after liver transplantation. This case highlights the need for awareness of drug-induced liver injury if liver function tests are elevated during treatment, especially in patients taking multiple potentially hepatotoxic drugs, such as broad-spectrum antibiotics. When occurs, an artificial liver support system is a useful tool to provide temporary support of liver function for the patient in the event of drug-induced liver injury.
Wei Qiu,Guo-Yue Lv,Chao Jiang,Ping Zhang,Xiao-Dong Sun,Xiao-Ju Shi,Xue-Yan Liu,Guang-Yi Wang 한국간담췌외과학회 2016 Annals of hepato-biliary-pancreatic surgery Vol.20 No.1
Acute graft-versus-host disease (GVHD) following liver transplantation is a rare but fatal complication. The correct diagnosis and management of GVHD after liver transplantation are still major challenges. Herein, we reported successful salvage treatment of acute GVHD by withdrawal of immunosuppression in a patient who presented with fever, skin rashes, and decreased blood cell counts after liver transplantation. This case highlights the need for awareness of drug-induced liver injury if liver function tests are elevated during treatment, especially in patients taking multiple potentially hepatotoxic drugs, such as broad-spectrum antibiotics. When occurs, an artificial liver support system is a useful tool to provide temporary support of liver function for the patient in the event of drug-induced liver injury.