Surface quality prediction model of nano-composite ceramics in ultrasonic vibration-assisted ELID mirror grinding

Bo Zhao,Fan Chen,Xiao-feng Jia,Chong-yang Zhao,Xiao-bo Wang 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.4

Ultrasonic vibration-assisted Electrolytic in-process dressing (ELID) grinding is a highly efficient and highly precise machining method. The surface quality prediction model in ultrasonic vibration-assisted ELID mirror grinding was studied. First, the interaction between grits and workpiece surface was analyzed according to kinematic mechanics, and the surface roughness model was developed. The variations in surface roughness under different parameters was subsequently calculated and analyzed by MATLAB. Results indicate that compared with the ordinary ELID grinding, ultrasonic vibration-assisted ELID grinding is superior, because it has more stable and better surface quality and has an improved range of ductile machining.

Proteomic Analysis of Erythritol-Producing Yarrowia lipolytica from Glycerol in Response to Osmotic Pressure(s)

( Li Bo Yang ),( Xiao Meng Dai ),( Zhi Yong Zheng ),( Li Zhu ),( Xiao Bei Zhan ),( Chi Chung Lin ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.7

Osmotic pressure is a critical factor for erythritol production with osmophilic yeast. Protein expression patterns of an erythritol-producing yeast, Yarrowia lipolytica, were analyzed toidentify differentially-expressed proteins in response to osmotic pressure. In order to analyze intracellular protein levels quantitatively, two-dimensional gel electrophoresis was performed to separate and visualize the differential expression of the intracellular proteins extracted from Y. lipolytica cultured under low (3.17 osmol/kg) and high (4.21 osmol/kg) osmotic pressures. Proteomic analyses allowed identification of 54 differentially-expressed proteins among the proteins distributed in the range of pI 3-10 and 14.4-97.4 kDa molecular mass between the osmotic stress conditions. Remarkably, the main proteins were involved in the pathway of energy, metabolism, cell rescue, and stress response. The expression of such enzymes related to protein and nucleotide biosynthesis was inhibited drastically, reflecting the growth arrest of Y. lipolytica under hyperosmotic stress. The improvement of erythritol production under highosmotic stress was due to the significant induction of a range of crucial enzymes related to polyols biosynthesis, such as transketolase and triosephosphate isomerase, and the osmotic stress responsive proteins like pyridoxine-4-dehydrogenase and the AKRs family. The polyols biosynthesis was really related to an osmotic response and a protection mechanism against hyperosmotic stress in Y. lipolytica. Additionally, the high osmotic stress could also induce other cell stress responses as with heat shock and oxidation stress responses, and these responsive proteins, such as the HSPs family, catalase T, and superoxide dismutase, also had drastically increased expression levels under hyperosmotic pressure.

Robust Optimization Dispatch Method for Distribution Network Considering Four-Quadrant Power Output of Energy Storage Devices

Li Yue,Xiao Xiao-Bing,He Xiao-Meng,Huang Bo-Yang,Fang Yang,He Xin-Yi 대한전기학회 2024 Journal of Electrical Engineering & Technology Vol.19 No.2

This paper describes a technique for improving distribution network dispatch by using the four-quadrant power output of distributed energy storage systems to address voltage deviation and grid loss problems resulting from the large integration of distributed generation into the distribution network. The approach creates an optimization dispatch model for an active distribution network. The objective function aims to minimize power purchase costs, network loss costs, and voltage deviation penalties. In addition, the method employs an interval robust optimization technique to handle uncertainties related to solar turbine output and load demand. To solve the optimal power fow problem for AC in the distribution network, this paper implements the second-order cone relaxation technique to convert it into a solvable second-order cone programming problem. Moreover, the Big-M method is used to handle the nonlinear terms in the objective function. Finally, simulation experiments are conducted on the IEEE33 node system to verify the efectiveness and superiority of the proposed method. The simulation results indicate that the system's operating cost can be signifcantly reduced. Additionally, it has a positive impact on reducing voltage deviation and system loss, ultimately improving the operation of the distribution network system.

Role of DNA Repair-related Gene Polymorphisms in Susceptibility to Risk of Prostate Cancer

Yang, Bo,Chen, Wei-Hua,Wen, Xiao-Fei,Liu, Hui,Liu, Feng Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

Aim: We assessed the association between genetic variants of XPG, XPA, XPD, CSB, XPC and CCNH in the nucleotide excision repair (NER) pathway and risk of prostate cancer. Methods: We genotyped the XPG, XPA, XPD, CSB, XPC and CCNH polymorphisms by a 384-well plate format on the MassARRAY(R) platform. Multivariate logistical regression analysis was used to assess the associations between the six gene polymorphisms and risk of prostate cancer. Results: Individuals carrying the XPG rs229614 TT (OR=2.01, 95%CI=1.35-3.27) genotype and T allele (OR=1.73, 95%CI=1.37-2.57) were moderately significantly associated with a higher risk of prostate cancer. Subjects with XPD rs13181 G allele had a marginally increased risk of prostate cancer, with adjusted OR(95%CI) of 1.53 (1.04-2.37). Moreover, individuals carrying with CSB rs2228526 GG genotype (OR=2.05, 95% CI=1.23-3.52) and G allele (OR=1.56, 95%CI=1.17-2.05) were associated with a higher increased risk of prostate cancer. The combination genotype of XPG rs2296147 T and CSB rs2228526 G allele had accumulative effect on the risk of this cancer, with an OR (95% CI) of 2.23(1.37-3.59). Conclusions: Our study indicates that XPG rs2296147 and CSB rs2228526 polymorphisms are significantly associated with increased risk of prostate cancer, and that combination of XPG rs2296147 T allele and CSB rs2228526 G allele is strongly associated with an increased risk.

Min-projection strategy with improved dynamic and steady state characteristics for three-phase grid-connected inverters

Yang, Bin,Xiao, Wenxun,Xie, Fan,Zhang, Bo,Chen, Yanfeng,Qiu, Dongyuan The Korean Institute of Power Electronics 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.9

The min-projection strategy (MPS) is a switching rule with better convergence speed, which can improve the dynamic characteristics of three-phase grid-connected inverters. However, the grid-connected current harmonics of the system are large when the MPS is used directly in the digital control framework due to the limitations of the sampling frequency. To solve this problem, an improved min-projection strategy is proposed in this paper by introducing a zero voltage vector to the control. First, the non-zero voltage vector is selected through the switching law function of the MPS. Then the time occupied by the non-zero voltage vector and the zero voltage vector can be obtained through an error function, which is established by the principle of minimum current error. Finally, the switching signal can be obtained for control, based on the method of duty cycle modulation. This method can realize fast current tracking and current decoupling control, reduce the grid-connected current harmonics, and improve the steady state performance of the system without increasing costs. The effectiveness of the proposed method is verified by simulations and experimental results.

Heat stress protection in Aspen sp1 transgenic Arabidopsis thaliana

( Bo Zhu ),( Ai Sheng Xiong ),( Ri He Peng ),( Jing Xu ),( Jun Zhou ),( Jin Tao Xu ),( Xiao Fen Jin ),( Yang Zhang ),( Xi Lin Hou ),( Quan Hong Yao ) 생화학분자생물학회 2008 BMB Reports Vol.41 No.5

Peniciside, a New Triterpenoid Glycoside, from the Fungus Penicillium sp. 169

Xiao-Hong Yuan,Guo-You Li,Guo-Bo Xu,Wei-Lin Wu,Tao Yang 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.2

Peniciside, a new fernene triterpenoid glycoside, was isolated from the EtOAc extract of the solid-state fermented rice culture of the fungus Penicillium sp. 169. Its structure was elucidated on the basis of spectroscopic analysis, and the absolute configuration was determined by X-ray crystallographic analysis and chemical methods. Peniciside is the first example of a fernene triterpenoid glycoside with two hydroxyls at C-19 and C-20.

Random Forest Classifier for Machine Fault Diagnosis

Xiao Di(디샤오),Tian Han(한천),Bo-Suk Yang(양보석) 대한기계학회 2006 대한기계학회 춘추학술대회 Vol.2006 No.11

This paper is to confirm the possibilities of applying random forests algorithm (RF) in machine fault diagnosis and propose a hybrid method combined with genetic algorithm to improve the classification accuracy. The proposed method is based on RF, a novel assemble classifier which builds a number of decision trees to improve on the single tree classifier. Although there are several existed techniques for faults diagnosis, the application research on RF is meaningful and necessary because of its fast execution speed, the characteristic of tree classifier, and high performance in machine faults diagnosis. Evaluation of RF based method has been demonstrated by a case study on induction motor faults diagnosis. Experimental results indicate the validity and reliability of RF based diagnosis method.

Methylated Alteration of SHP1 Complements Mutation of JAK2 Tyrosine Kinase in Patients with Myeloproliferative Neoplasm

Yang, Jun-Jun,Chen, Hui,Zheng, Xiao-Qun,Li, Hai-Ying,Wu, Jian-Bo,Tang, Li-Yuan,Gao, Shen-Meng Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.6

SHP1 negatively regulates the Janus kinase 2/signal transducer and activator of transcription (JAK2/STAT) signaling pathway, which is constitutively activated in myeloproliferative neoplasms (MPNs) and leukemia. Promoter hypermethylation resulting in epigenetic inactivation of SHP1 has been reported in myelomas, leukemias and other cancers. However, whether SHP1 hypermethylation occurs in MPNs, especially in Chinese patients, has remained unclear. Here, we report that aberrant hypermethylation of SHP1 was observed in several leukemic cell lines and bone marrow mononuclear cells from MPN patients. About 51 of 118 (43.2%) MPN patients including 23 of 50 (46%) polycythaemia vera patients, 20 of 50 (40%) essential thrombocythaemia and 8 of 18 (44.4%) idiopathic myelofibrosis showed hypermethylation by methylation-specific polymerase chain reaction. However, SHP1 methylation was not measured in 20 healthy volunteers. Hypermethylation of SHP1 was found in MPN patients with both positive (34/81, 42%) and negative (17/37, 45.9%) JAK2V617F mutation. The levels of SHP1 mRNA were significantly lower in hypermethylated samples than unmethylated samples, suggesting SHP1 may be epigenetically inactivated in MPN patients. Furthermore, treatment with 5-aza-2'-deoxycytidine (AZA) in K562 cells showing hypermethylation of SHP1 led to progressive demethylation of SHP1, with consequently increased reexpression of SHP1. Meanwhile, phosphorylated JAK2 and STAT3 were progressively reduced. Finally, AZA increased the expression of SHP1 in primary MPN cells with hypermethylation of SHP1. Therefore, our data suggest that epigenetic inactivation of SHP1 contributes to the constitutive activation of JAK2/STAT signaling. Restoration of SHP1 expression by AZA may contribute to clinical treatment for MPN patients.

Nuclide assignment for an isolated band observed in the 10B + 114Cd reaction

Yang Qing-Yu,Song Li-Na,Ma Ying-Jun,Yang Dong,Ma Ke-Yan,Wu Xiao-Guang,Zheng Yun,Li Cong-Bo 한국물리학회 2021 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.79 No.3

Three experiments based on the nuclear reactions 14N + 110Pd, 10B + 114Cd and 11B + 114Cd were performed. Coincidences between γ-rays emitted from these reactions were measured with the same detection array which consisted of 14 HPGe detectors. A new band structure was identified using an offline analysis of coincidence data. Because of the isomeric nature of the bandhead, the new band cannot be connected to any known state in any residual nuclei of the used reactions. To assign it to a specific nucleus, we evaluated the experimental population intensities of various known bands in known residual nuclei and investigated the entrance channel effects in the three different experiments. The population intensity patterns of the known bands were observed to exhibit regular systematics. Based on such experimental systematics, we suggest that the most reasonable nuclide assignment for the new band is the 120I nucleus.