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      • KCI등재

        Effect of Monascus as a Nitrite Substitute on Color, Lipid Oxidation, and Proteolysis of Fermented Meat Mince

        Xiang Yu,Haizhou Wu,Jianhao Zhang 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.2

        Monascus spp. are fungi, traditionally eaten in Asian countries, that have the the potential to be used as a nitrite substitute in meat-product processing. Effects of using Monascus ruber MJ-1 as a nitrite substitute on color, lipid oxidation and proteolysis of fermented meat mince were investigated in this study. After 4 days of fermentation, a* and L* values for the samples were significantly higher and lower than the values for the control, respectively; however, b* values were significantly lower than that of the control throughout the fermentation process (p<0.05). Furthermore, Monascus ruber MJ-1 fermentation decreased the thiobarbituric acid reactive substances (TBARs) value and increased the myofibril fragmentation index (MFI) value of meat mince significantly (p<0.05). SDS-PAGE results further indicated that myofibrillar proteins were degraded during fermentation, while sarcoplasmic proteins were not. These results suggest prospects for the broad application of Monascus as a nitrite substitute in meat processing.

      • KCI등재

        Joyce Study in China

        Lui Xiangyu 한국제임스조이스학회 2006 제임스조이스저널 Vol.12 No.2

        Joyce Study in China Liu Xiangyu The study of James Joyce in China might be described as three stages. The first stage starts from the year when Ulysses was published in 1922 and some modern Chinese writers noticed it and introduced it briefly here and there in Chinese periodicals to the year 1977 when China was ready to be open again to the Western cultures. The second stage is from 1978 to 1993 when the first Chinese version of Ulysses came out. The third stage is from 1993 to the present.

      • KCI등재

        Analysis of skid damage to cylindrical roller bearing of mainshaft of aeroengine

        Xiangyu Xie,Jin Xu,Jun Luo 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.8

        Skid damage to mainshaft bearings on aeroengines severely reduces aircraft reliability. In this study, a batch of cylindrical roller bearings extracted from mainshaft of inservice aeroengines with, skid damage after a certain service period, were collected, and damage features of the bearings were characterized and compared with those of the undamaged bearings and the new ones. Microscopic feature evaluation, elemental analysis as well as the composition distribution of the bearings were conducted using scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffractometry, X-ray photoelectron spectroscopy, transmission electron microscopy and surface profilometry. Analysis results reveal that skidding itself is a very complex process initiated by the action of different mechanisms, and manifest in different wear types. The damage mechanism of skid damaged bearings was the joint consequence of abrasive wear, oxidation wear and delamination wear. All the aforementioned damage and wear led to severe aircraft failures.

      • KCI등재

        An Improved Mathematical Calculation Method for Beam String Structure Based on Static Equilibrium Principle

        Xiangyu Yan,Hong Hu,Zhi-Hua Chen,Yan Yang 한국강구조학회 2020 International Journal of Steel Structures Vol.20 No.4

        The beam string structure (BSS) has been widely applied to public buildings (e.g. sports venues and exhibition centers) for its strong adaptability to architectural form and reasonable load bearing mechanism. However, most mathematical calculation methods for BSS are too complicated to be generally mastered by structural engineers, which limits the promotion and actual application. In this paper, two analytical calculation methods for the BSS are proposed based on displacement control objectives and work-energy principle. The computational formulas are then derived to calculate the member internal force and structural deformation. On this basis, the tension and static load tests and the fi nite element analytical method have been carried out to assess the calculation methods. The results of the tests and simulation are in good agreement with the analytical solution obtained by the computational formulas. Moreover, the formulas can be more appropriate with a greater beam span, proper rise–span and sag–span ratios (between 1/15 and 1/12) as well as more brace struts.

      • KCI등재

        A Distributed Implementation Algorithm for Physical Layer Security Based on Untrusted Relay Cooperation and Artificial Noise

        Xiangyu Li,Xueming Wang,Xiangyang Xu,Liang Jin 한국전자통신연구원 2014 ETRI Journal Vol.36 No.1

        In this letter, we consider a cooperation system with multipleuntrusted relays (URs). To keep the transmitted informationconfidential, we obtain joint channel characteristics (JCCs)through combining the channels from the source to thedestination. Then, in the null space of the JCCs, jammersconstruct artificial noise to confuse URs when the source nodebroadcasts its data. Through a distributed implementationalgorithm, the weight of each node can be obtained from itsown channel state information. Simulation results show thathigh-level security of the system can be achieved when internaland external eavesdroppers coexist.

      • KCI등재

        Association analysis of polymorphism in the NR6A1 gene with the lumbar vertebrae number traits in sheep

        Xiangyu Zhang,Cunyuan Li,Xiaoyue Li,Zhijin Liu,Wei Ni,Yang Cao,Yang Yao,Esenbay Islamov,Junchang Wei,Xiaoxu Hou,Shengwei Hu 한국유전학회 2019 Genes & Genomics Vol.41 No.10

        Introduction The vertebral number is an economically significant trait, which is associated with body length and carcass traits. Nuclear Receptor Subfamily 6, Group A, Member 1 (NR6A1) is a member of the nuclear receptor superfamily and it plays an important role in the early development of embryos. Objectives The NR6A1 gene was considered as an important candidate for influence vertebrae number, while the potential associations between this gene and the number of lumbar vertebrae traits of sheep have not been explored. Methods In this study, we detected the genetic variants of NR6A1 gene and analyzed the associations of the polymorphisms with lumbar number traits in 130 Kazakh sheep. We use single-strand conformation polymorphism (SSCP) technique to detect single nucleotide polymorphism (SNP) of NR6A1 gene, and the association of the genotype and lumbar number variation was analyzed by independent Chi-square test. Results We detect SNP of NR6A1 gene by PCR-SSCP technique, and polymorphisms were only found in the coding region of exon-6 and exon-8 of NR6A1 gene. In order to investigate the connection between the SNP locus and lumbar number traits in sheep, we conducted a Chi-square test for independence for exon-6 and exon-8 of NR6A1 gene, respectively. Association analysis revealed significant associations between the SNP (rs414302710: A >C) in the exon-8 of NR6A1 gene with the number of lumbar vertebrae (P < 0.01). Conclusion Our study indicated that this SNP (rs414302710: A>C) locus of exon-8 of NR6A1 gene in sheep possible influence the number of lumbar vertebrae, which has the potential to be applied in selective breeding of sheep.

      • KCI등재

        Double-sided collaborative machining for propeller blade based on XYZ-3RPS hybrid kinematic machine

        Xiangyu Guo,Rui Wang,Shi-Sheng Zhong 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.10

        At present, propeller blades are machined single-sided with low efficiency. Thus, a propeller needs to be turned over after completion of the machining of the first side of the blade, which requires second clamping and causes a decline in accuracy. Therefore, a doublesided collaborative machining method for propeller blades is proposed herein. Two XYZ-3RPS hybrid kinematics machines were symmetrically distributed to machine both sides of a propeller blade simultaneously; therefore, the blade could be machined in clamping once, improving the machining efficiency and eliminating the accuracy decline caused by repetitive clamping. Moreover, a supporting device with rigid-flexible switching capability was developed to reduce the cantilever length of the blade, thereby eliminating the substantial deformation and vibration of the blade during the double-sided collaborative machining process to ensure machining accuracy. Additionally, the inverse kinematics formula for XYZ-3RPS hybrid kinematics machines was deduced and the elongation of each drive shaft through the cutter location point and cutter orientation was solved in this study. Thereafter, the decomposition method of the blade shift data was applied to obtain the deformation and vibration amplitude of the blade so that the performance of the double-sided cooperative machining could be quantitatively analyzed. Finally, experiments were conducted on the self-developed prototype, and the results verified the effectiveness of the double-sided collaborative machining method in reducing the deformation and vibration of a blade and improving machining efficiency.

      • KCI등재

        Collision avoidance and orientation planning for ball-end cutter

        Xiangyu Guo,Rui Wang,Shi-Sheng Zhong 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.8

        Propeller blades have freeform surfaces, and the overlap among the blades limits the adjustment range of cutter orientation, making it extremely difficult to generate the required cutter orientation. Therefore, to assist in quickly designing a safe and reasonable machining scheme, a projection-offset method is designed to calculate the feasible region of a ballend cutter and an XYZ-3RPS hybrid kinematic mechanism. Based on this, a reasonable and smooth cutter orientation can be generated using path-planning and trajectory-optimization algorithms. To this end, a method for obtaining point clouds was first developed. By arranging the point clouds of a blank in the cutter path order, the changes to the blank during the machining process can be reflected through point-cloud deletion. A hierarchical bounding box is established for the moving platform of the cutter, spindle, and mechanism, which can realize the quick screening and classification of collision-point clouds. Second, the collision points are projected onto the same plane, an envelope boundary of the projected point cloud was constructed using an alpha-shapes algorithm, and its cross boundary trimmed using the auxiliary boundary method to obtain the feasible region at the cutter contact point. Moreover, to reduce the computational load, an interpolation method, which reduces the number of calculations, is used. The basic rules for cutter-orientation generation were established using a planning function. Then, the cutter-orientation path was smoothed using the trajectory-optimization algorithm to prevent the cutter from swinging violently. Finally, the effectiveness of this method was verified through propeller experiments.

      • KCI등재

        LncRNA MEG3 Regulates Imatinib Resistance in Chronic Myeloid Leukemia via Suppressing MicroRNA-21

        ( Xiangyu Zhou ),( Ping Yuan ),( Qi Liu ),( Zhiqiang Liu ) 한국응용약물학회 2017 Biomolecules & Therapeutics(구 응용약물학회지) Vol.25 No.5

        Imatinib resistance has become a major clinical problem for chronic myeloid leukemia. The aim of the present study was to investigate the involvement of MEG3, a lncRNA, in imatinib resistance and demonstrate its underlying mechanisms. RNAs were extracted from CML patients` peripheral blood cells and human leukemic K562 cells, and the expression of MEG3 was measured by RT-qPCR. Cell proliferation and cell apoptosis were evaluated. Western blotting was used to measure the protein expression of several multidrug resistant transporters. Luciferase reporter assay was performed to determine the binding between MEG3 and miR-21. Our results showed that MEG3 was significantly decreased in imatinib-resistant CML patients and imatinib-resistant K562 cells. Overexpression of MEG3 in imatinib-resistant K562 cells markedly decreased cell proliferation, increased cell apoptosis, reversed imatinib resistance, and reduced the expression of MRP1, MDR1, and ABCG2. Interestingly, MEG3 binds to miR-21. MEG3 and miR-21 were negatively correlated in CML patients. In addition, miR-21 mimics reversed the phenotype of MEG3-overexpression in imatinib-resistant K562 cells. Taken together, MEG3 is involved in imatinib resistance in CML and possibly contributes to imatinib resistance through regulating miR-21, and subsequent cell proliferation, apoptosis and expression of multidrug resistant transporters.

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