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Yi Luan,Wenbin Zhang,Min Wang,Pei Zhang,Zhimin Xue,Guosheng Fu,Junbo Ge 한국유전학회 2016 Genes & Genomics Vol.38 No.9
The methylenetetrahydrofolate reductase (MTH FR) gene variant 677C?T is considered a risk factor for myocardial infarction (MI) in Caucasians, but it remains unclear whether this applies to Chinese or other Asian populations. A total of 551 controls and 304 age-matched Chinese MI patients were recruited. MTHFR genotypes were determined. A subsequent meta-analysis was performed to determine the association between MTHFR and MI in Asia. Conventional risk factors such as hypertension, diabetes mellitus and low-density lipoprotein exhibited no significant differences between the two groups. Genotype frequencies among cases and controls were compatible with Hardy– Weinberg equilibrium. The frequencies of CC, CT and TT genotypes were 28, 46 and 26 % for patients with MI and 31, 52 and 17 % for the matched control group (p = 0.006). T-allele frequency in MI patients was higher than in controls (49 vs. 43 %, odds ratio = 0.785, 95 % confidence interval = 0.644–0.958, p = 0.017). A total of 16 studies including ours were identified, involving 4053 patients and 6791 controls. A recessive genotype model of MTHFR 677C?T polymorphism, but not a dominant genotypemodel, was significantly associated with greater MIrisk in Asians. MI risk increased 48, 37 and 47 % for the TT homozygote compared with the CC wild type, CT heterozygote and the combination of CT and CC. Thus, we conclude that the MTHFR gene variant 677C?T is a risk factor for MI in the Chinese population and the TT genotype is associated with a significant increase in MI risk in Asia.
Zhang Xin,Li Chunzhi,Xue Ming,Wang Wenbin,Zhu Lihua 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.3
The suppression of vibration and noise is one of the critical problems in the optimal design of the motor. The vibration and noise caused by the magnetostrictive effect can not be ignored. In this paper, the vibration and noise caused by the magnetostrictive effect are suppressed by drilling holes in the stator and filling the holes with negative magnetostrictive material. Firstly, the electromagnetic–mechanical coupling model is established. By traversing all the drilling positions by finite element analysis (FEA), the stress value is calculated, and the drilling position corresponding to the minimum local stress is determined. It is found that the resource consumed by FEA is expensive, and the calculation time is prolonged. Deep learning is introduced as an alternative model to calculate the hole’s position and size. The Pix2Pix, Pix2PixHD, CycleGAN, and StarGAN are experimented with based on the PyTorch environment. Through the experiment, it is found that deep learning has an absolute advantage over the FEA in time which ensures a high accuracy rate. Finally, an experimental platform for measuring the strain of the motor stator is designed. According to the best positions and apertures of holes are obtained by the simulation and the actual situation, we drill holes in the motor stator and fill the holes with Ni, a negative magnetostrictive material. The result shows that the stator’s local stress is reduced by about 16%. The vibration and noise caused by the magnetostrictive effect are suppressed effectively.
Wang, Hongchao,Hwang, Junphil,Zhang, Chao,Wang, Teng,Su, Wenbin,Kim, Hoon,Kim, Jungwon,Zhai, Jinze,Wang, Xue,Park, Hwanjoo,Kim, Woochul,Wang, Chunlei Royal Society of Chemistry 2017 Journal of Materials Chemistry A Vol.5 No.27
<P>SnTe alloys, which have the same crystal structure as PbTe, have attracted increasing attention. Here, we demonstrate that the synergistic effect of band structure modification and chemical bond softening can be realized simultaneously in In & Mn doped SnTe bulk alloys. The Seebeck coefficient and power factor are synergistically improved by co-doping of In and Mn. In doping is known to introduce a resonance level. Mn doping reduces the separation of light- and heavy-valence bands. The combination of these effects significantly enhances the Seebeck coefficient at room temperature owing to around a factor of five times increase in the band effective mass. The reduction of thermal conductivity is from the decrease of both the electronic and phononic parts. The electronic thermal conductivity is decreased by the increase in defect scattering, as can be confirmed by the carrier mobility. The force constant of the bonds around the Te site is decreased due to the co-doping of In & Mn, which indicates that the chemical bonds are softened, which leads to low sound velocity and lower lattice thermal conductivity. As a result, the peak thermoelectric figure of merit,<I>zT</I>= 1.03 has been achieved for Sn0.89In0.01Mn0.1Te at 923 K. This strategy of using the synergistic effect of band structure modification and chemical bond softening could be applicable to other thermoelectric materials.</P>