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RISS 인기검색어
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- 저자 : Wang Xinxia (검색결과 4 건)
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Dual-Phase Shifting Strategy for CLLC Resonant Converters
Wang Dangshu,Zhao Licong,Chang Menghu,Yang Yuxuan,Guan Zhimin,Zhang Ruchuan,Wang Xinxia 대한전기학회 2024 Journal of Electrical Engineering & Technology Vol.19 No.4
The CLLC resonant converter has the advantages of bidirectional power transmission, natural soft switching, and wide range voltage output. However, the gain curve is relatively smooth during high-frequency light-load operation, and it is diffi cult to adjust through frequency conversion; the traditional fundamental harmonic approximation (FHA) method has a large error in calculating the gain at a position away from the resonance point, which brings diffi culties to the design. In order to better design the converter, this paper proposes a dual phase-shift (DPS) control method based on time-domain analysis, which can achieve a wide voltage range output without losing soft switching, and has constant current source output characteristics. Firstly, the time-domain model of the CLLC converter is analyzed, and the output voltage gain and soft switching range under DPS control are solved; then a simulation is built for verifi cation; fi nally, a 200/80 V, rated power 500 W full-bridge CLLC resonant converter experimental prototype is built. The experimental results prove that the converter has good soft switching range and constant current source output characteristics.
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Targeted Editing of Myostatin Gene in Sheep by Transcription Activator-like Effector Nucleases
Zhao, Xinxia,Ni, Wei,Chen, Chuangfu,Sai, Wujiafu,Qiao, Jun,Sheng, Jingliang,Zhang, Hui,Li, Guozhong,Wang, Dawei,Hu, Shengwei Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.3
Myostatin (MSTN) is a secreted growth factor expressed in skeletal muscle and adipose tissue that negatively regulates skeletal muscle mass. Gene knockout of MSTN can result in increasing muscle mass in sheep. The objectives were to investigate whether myostatin gene can be edited in sheep by transcription activator-like effector nucleases (TALENs) in tandem with single-stranded DNA oligonucleotides (ssODNs). We designed a pair of TALENs to target a highly conserved sequence in the coding region of the sheep MSTN gene. The activity of the TALENs was verified by using luciferase single-strand annealing reporter assay in HEK 293T cell line. Co-transfection of TALENs and ssODNs oligonucleotides induced precise gene editing of myostatin gene in sheep primary fibroblasts. MSTN gene-edited cells were successfully used as nuclear donors for generating cloned embryos. TALENs combined with ssDNA oligonucleotides provide a useful approach for precise gene modification in livestock animals.
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Guangdong Yang,Gaohui Wang,Wenbo Lu,Peng Yan,Ming Chen,Xinxia Wu 대한토목학회 2018 KSCE Journal of Civil Engineering Vol.22 No.8
The damage prediction of high dams under the attacks of earth-penetrating weapons has gained significant importance in recentyears. For this purpose, a SPH-Lagrangian-Eulerian coupled approach is proposed to describe the damage processes of concretegravity dams subjected to the combined action of the penetration and explosion. The SPH method is used to model the concretematerial with the large deformation near the penetration and explosion regions. The Lagrangian algorithm is adopted to simulate thehigh-velocity projectile and dam body with the small distortion. And the Eulerian algorithm is employed to describe the dynamicbehavior of the water and air media. The validity of the penetration model is calibrated against a previous penetration test. Meanwhile, the SPH-Lagrangian-Eulerian coupled method is verified by implementing an underwater explosion test in a concretecube. The computed distribution of cracking damage is consistent with the result of the experimental test, which validates the validityof the proposed SPH-Lagrangian-Eulerian coupling method. Subsequently, the penetration processes of a concrete gravity dam underthe high-velocity projectile are presented. After the rapid penetration, the explosives are detonated in the dam with the initialpenetration damage. The shock wave propagation characteristics in the dam and reservoir water are discussed. The failure processesand dynamic responses of the dam subjected to the combined action of the penetration and explosion are investigated. The influenceof the initial penetration damage and the reservoir water on the failure processes of the dam subjected to the internal blast loading is alsodiscussed. The results show that the penetration of the high-velocity projectile only causes a local damage to the concrete gravity dam. However, the combined effects of the penetration and explosion cause significantly more damage to the upper region of the dam.
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