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      • KCI등재후보

        Tests and finite element analysis on the local buckling of 420 MPa steel equal angle columns under axial compression

        G. Shi,Z. Liu,H.Y. Ban,Y. Zhang,Y.J. Shi,Y.Q. Wang 국제구조공학회 2012 Steel and Composite Structures, An International J Vol.12 No.1

        Local buckling can be ignored for hot-rolled ordinary strength steel equal angle compression members, because the width-to-thickness ratios of the leg don’t exceed the limit value. With the development of steel structures, Q420 high strength steel angles with the nominal yield strength of 420 MPa have begun to be widely used in China. Because of the high strength, the limit value of the width-to-thickness ratio becomes smaller than that of ordinary steel strength, which causes that the width-to-thickness ratios of some hot-rolled steel angle sections exceed the limit value. Consequently, local buckling must be considered for 420 MPa steel equal angles under axial compression. The existing research on the local buckling of high strength steel members under axial compression is briefly summarized, and it shows that there is lack of study on the local buckling of high strength steel equal angles under axial compression. Aiming at the local buckling of high strength steel angles, this paper conducts an axial compression experiment of 420MPa high strength steel equal angles, including 15 stub columns. The test results are compared with the corresponding design methods in ANSI/AISC 360-05 and Eurocode 3. Then a finite element model is developed to analyze the local buckling behavior of high strength steel equal angles under axial compression, and validated by the test results. Followingthe validation, a finite element parametric study is conducted to study the influences of a range of parameters, and the analysis results are compared with the design strengths by ANSI/AISC 360-05 and Eurocode 3.

      • SCISCIESCOPUS

        Spontaneous Hepatocellular Carcinoma after the Combined Deletion of Akt Isoforms

        Wang, Q.,Yu, W.N.,Chen, X.,Peng, X.d.,Jeon, S.M.,Birnbaum, M.J.,Guzman, G.,Hay, N. Cell Press 2016 CANCER CELL Vol. No.

        Akt is frequently hyperactivated in human cancers and is targeted for cancer therapy. However, the physiological consequences of systemic Akt isoform inhibition were not fully explored. We showed that while combined Akt1 and Akt3 deletion in adult mice is tolerated, combined Akt1 and Akt2 deletion induced rapid mortality. Akt2<SUP>-/-</SUP> mice survived hepatic Akt1 deletion but all developed spontaneous hepatocellular carcinoma (HCC), which is associated with FoxO-dependent liver injury and inflammation. The gene expression signature of HCC-bearing livers is similar to aggressive human HCC. Consistently, neither Akt1<SUP>-/-</SUP> nor Akt2<SUP>-/-</SUP> mice are resistant to diethylnitrosamine-induced hepatocarcinogenesis, and Akt2<SUP>-/-</SUP> mice display a high incidence of lung metastasis. Thus, in contrast to other cancers, hepatic Akt inhibition induces liver injury that could promote HCC.

      • Automated quality assessment of precast concrete elements with geometry irregularities using terrestrial laser scanning

        Wang, Q.,Kim, M.K.,Cheng, J.C.P.,Sohn, H. Elsevier ; Elsevier Science Pub. Co 2016 AUTOMATION IN CONSTRUCTION - Vol.68 No.-

        Precast concrete elements are popularly used and it is important to ensure that the dimensions of individual elements conforms to design codes. However, the current quality assessment of precast concrete elements is inaccurate and time-consuming. To address the problems, this study presents an automated quality assessment technique which estimates the dimensions of precast concrete elements with geometry irregularities using terrestrial laser scanners (TLS). While the scan data obtained from TLS represent the as-built condition of an element, a Building Information Modeling (BIM) model stores the as-design condition of the element. Taking the BIM model as a reference, the scan data are processed to estimate the as-built dimensions of the element. Experiments on a specimen demonstrated that the proposed technique can estimate the dimensions of elements effectively and accurately. Furthermore, a mirror-aided scanning approach, which aims to achieve reduced incident angles in real scanning environments, is proposed and validated by experiments.

      • SCIESCOPUS

        On complex flutter and buckling analysis of a beam structure subjected to static follower force

        Wang, Q. Techno-Press 2003 Structural Engineering and Mechanics, An Int'l Jou Vol.16 No.5

        The flutter and buckling analysis of a beam structure subjected to a static follower force is completely studied in the paper. The beam is fixed in the transverse direction and constrained by a rotational spring at one end, and by a translational spring and a rotational spring at the other end. The co-existence of flutter and buckling in this beam due to the presence of the follower force is an interesting and important phenomenon. The results from this theoretical analysis will be useful for the stability design of structures in engineering applications, such as the potential of flutter control of aircrafts by smart materials. The transition-curve surface for differentiating the two distinct instability regions of the beam is first obtained with respect to the variations of the stiffness of the springs at the two ends. Second, the capacity of the follower force is derived for flutter and buckling of the beam as a function of the stiffness of the springs by observing the variation of the first two frequencies obtained from dynamic analysis of the beam. The research in the paper may be used as a benchmark for the flutter and buckling analysis of beams.

      • SCIESCOPUSKCI등재

        Efficacy of Cr (III) Supplementation on Growth, Carcass Composition, Blood Metabolites, and Endocrine Parameters in Finishing Pigs

        Wang, M.Q.,He, Y.D.,Lindemann, M.D.,Jiang, Z.G. Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.10

        The study was conducted to evaluate the effects of trivalent chromium from different sources on growth, carcass composition, and serum parameters in finishing pigs. Ninety-six crossbred pigs with an initial average body weight of 65.57${\pm}$1.05 kg were blocked by body weight and randomly assigned to four treatments with three replicates. Pigs were offered one of four diets including a control diet or the control diet supplemented with 200 ${\mu}g/kg$ chromium from either chromium chloride ($CrCl_{3}$), chromium picolinate (CrPic) or chromium nanocomposite (CrNano) for 40 days. After completion of the feeding trial, eight pigs from each treatment were selected to collect blood samples, and slaughtered to measure carcass composition. The results showed that supplemental chromium had no significant effect on growth performance, while CrNano increased carcass lean proportion and loin Longissimus muscle area (p<0.05), and decreased carcass fat proportion and 10th rib backfat depth (p<0.05). CrPic supplementation also resulted in lower fat proportion and larger Longissimus muscle area (p<0.05). The addition of Cr from CrNano or CrPic decreased serum glucose (p<0.05) and increased concentrations of total protein and free fat acid in serum (p<0.05). Serum urea nitrogen, triglyceride and cholesterol were decreased (p<0.05), and serum high density lipoprotein and lipase activity were increased (p<0.05) with the supplementation of CrNano. Serum insulin was decreased (p<0.05) by supplemental Cr from CrNano or CrPic, and serum insulin-like growth factor I was increased significantly in the CrNano treated group. These results suggest that chromium nanocomposite has higher efficacy on carcass composition in pigs compared to the traditional chromium sources.

      • SCIESCOPUSKCI등재

        Genetic Diversity of Chinese Indigenous Pig Breeds in Shandong Province Using Microsatellite Markers

        Wang, J.Y.,Guo, J.F.,Zhang, Q.,Hu, H.M.,Lin, H.C.,Wang, Cheng,Zhang, Yin,Wu, Y. Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.1

        To investigate the genetic diversity of six Chinese indigenous pig breeds in Shandong province (Laiwu Black, Dapulian Black, Licha Black, Yantai Black, Yimeng Black and Wulian Black), explain their genetic relationship and assess their integrity and degree of admixture with three Western commercial breeds (Landrace, Yorkshire and Duroc), 303 individuals from these breeds were genotyped for 26 microsatellite markers. In general, high genetic diversity (observed heterozygosity ranging from 0.5495 to 0.7746) and large breed differentiation ($F_{ST}$ = 0.188) were observed. The indigenous pig breeds in Shandong exhibited consistently higher levels of genetic diversity than the three Western breeds. However, compared with the Western breeds, which have an $F_{ST}$ value of 0.252, the indigenous breeds in Shandong have smaller $F_{ST}$ value of 0.145. The analysis of breed relationship indicated that the six indigenous breeds are classified into two groups. One includes four breeds, Licha, Yantai, Yimeng and Wulian, which have experienced large gene introgression of the Western breeds through progressive crossbreeding as well as gene flow among themselves. The other includes Laiwu and Dapulian, which are less influenced by the Western breeds and other indigenous breeds in Shandong in the recent past. The results show that some measures must be taken to effectively protect these indigenous pig breeds in Shandong.

      • Evaluating the effectiveness of ERS for vessel oil spills using fuzzy evidential reasoning

        Wang, H.Y.,Ren, J.,Yang, J.Q.,Wang, J. Techno-Press 2015 Ocean systems engineering Vol.5 No.3

        An emergency response system (ERS) for vessel oil spills is a complex and dynamic system comprising a number of subsystems and activities. Failures may occur during the emergency response operations, this has negative impacts on the effectiveness of the ERS. Of the classes of problems in analyzing failures, the lack of quantitative data is fundamental. In fact, most of the empirical data collected via questionnaire survey is subjective in nature and is inevitably associated with uncertainties caused by the human being's inability to provide complete judgement. In addition, incomplete information and/or vagueness of the meaning about the failures add difficulties in evaluating the effectiveness of the system. Therefore this paper proposes a framework to evaluate the ERS effectiveness by using the combination of fuzzy reasoning and evidential synthesis approaches. Based on analyzing the procedure of ERS for oil spills, the failures in the system could be identified, using Analytic Hierarchy Process(AHP)to determine the relative weight of identified failures. Fuzzy reasoning combined with evidential synthesis is applied to evaluate the effectiveness of ERS for oil spills under uncertainties last. The proposed method is capable of dealing with uncertainties in data including ignorance and vagueness which traditional methods cannot effectively handle. A case study is used to illustrate the application of the proposed method.

      • SCIESCOPUSKCI등재

        Energy and Ileal Digestible Amino Acid Concentrations for Growing Pigs and Performance of Weanling Pigs Fed Fermented or Conventional Soybean Meal

        Wang, Y.,Lu, W.Q.,Li, D.F.,Liu, X.T.,Wang, H.L.,Niu, S.,Piao, X.S. Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.5

        A new strategy of co-inoculating Bacillus subtilis MA139 with Streptococcus thermophilus and Saccharomyces cerevisiae was used to produce fermented soybean meal (FSBM). Three experiments were conducted to determine the concentration of digestible energy (DE) and metabolizable energy (ME) (Exp. 1), apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of amino acids (AA) (Exp. 2), and feeding value (Exp. 3) of FSBM produced by this new strategy (NFSB) compared with soybean meal (SBM) and conventionally available FSBM (Suprotein). In Exp. 1, twenty-four barrows (initial body weight [BW] of $32.2{\pm}1.7kg$) were randomly allotted to 1 of 4 diets with 6 replicates per diet. A corn basal diet and 3 diets based on a mixture of corn and 1 of 3 soybean products listed above were formulated and the DE and ME contents were determined by the difference method. The results showed that there were no differences in DE and ME between SBM and either FSBM product (p>0.05). In Exp. 2, eight barrows (initial BW of $26.8{\pm}1.5kg$) were fitted with ileal T-cannulaes and used in a replicated $4{\times}4$ Latin square design. Three corn-starch-based diets were formulated using each of the 3 soybean products as the sole source of AA. A nitrogen-free diet was also formulated to measure endogenous losses of AA. The results showed that the SID of all AA except arginine and histidine was similar for NFSB and SBM (p>0.05), but Suprotein had greater (p<0.05) SID of most AA except lysine, aspartate, glycine and proline than NFSB. In Exp. 3, a total of 144 piglets (initial BW of $8.8{\pm}1.2$ kg) were blocked by weight and fed 1 of 4 diets including a control diet with 24% SBM as well as diets containing 6% and 12% NFSB or 12% Suprotein added at the expense of SBM. During d 15 to 28, replacing SBM with 6% NFSB significantly improved average daily gain (ADG) and average daily feed intake (ADFI) (p<0.05) for nursery piglets. During the overall experiment, ADG of piglets fed diets containing 6% NFSB was significantly greater (p<0.05) than that of piglets fed SBM. In conclusion, fermentation with the new strategy did not affect the energy content or the AID and the SID of AA in SBM. However, inclusion of 6% NFSB in diets fed to nursery piglets improved performance after weaning likely as a result of better nutritional status and reduced immunological challenge.

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