Stereotactic Body Radiation Therapy in Stage I Non-small Cell Lung Cancer Patients with Peripheral Tumors in Vietnam

( Luan Pham Van ),( Tien Nguyen Dinh ),( Ha Le Ngoc ),( Son Mai Hong ),( Bieu Bui Quang ),( Tuan Nguyen Van ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-

Objective Stereotactic Body Radiation Therapy (SBRT) was indicated for early-stage non-small cell lung cancer (NSCLC) patients inoperable. The purpose of the study was evaluated the result of SBRT in stage I NSCLC patients (T1-2aN0M0) with peripheral tumors. Methods Prospective, follow-up 23 patients with stage T1-2aN0M0 NSCLC with peripheral tumor, who were received SBRT, followup and evaluated from January, 2015 to January, 2020. The primary endpoints were Objective Response Rate (ORR), Disease Control Rate (DCR), Progression Free Survival (PFS), the second endpoints were Overall Survival (OS) and Toxicity. Results The average age was 65.13 years-old, the mean of diameter was 3.31cm, the mean of SUVmax value was 7.77. The stage of the tumor is mostly T2a (60,9%). The median of follow-up was 26 months, ORR was 91.3%, DCR was 95.7%. The median PFS was 26 months, median OS was 58 months, the ratio of OS in 1 year, 2 years, 3 years, 4 years, 5 years were 95.7%, 65.2%, 39.1%, 26.1% and 17.4%, respectively. The common of adverse events was pneumonitis due to SBRT at 9 patients, but mainly was grade 1, no patients have pneumonitis grade 4 and 5. No clinically significant changes in pulmonary function following SBRT for earlystage NSCLC. Conclusion SBRT was a good option for patients with stage I NSCLC, there was no significant difference in survival between patients who refused surgery and those who have medical inoperable and this is a safe treatment for patients.

Mechanisms of Methylene Blue Degradation by Nano-Sized β-MnO2 Particles

Van Luan Pham,김도군,고석오 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.5

Degradation of a dye by 1-D nano-sized β-MnO2 particles was investigated to understand the mechanisms involved. Batch experiments were performed in a system of β-MnO2, hydrogen peroxide (H2O2), methylene blue (MB), and radical scavengers. The prepared β-MnO2 had a 1-dimensional nano-sized structure and showed a negative zeta potential at pH higher than 3.7. In the presence of H2O2, MB was rapidly degraded by β-MnO2. The rate of MB degradation was not significantly inhibited by the initial pH values from 6.05 to 10.02, but notably decreased at pH 3.04, at which point the β-MnO2 particles dissolved. The effect mechanisms of operational parameters (i.e., H2O2, catalyst dose) in β-MnO2/MB/H2O2 system were investigated. The removal rate of MB was remarkably reduced in the existence of p-quinone and was even more affected when sodium azide was added, indicating that the singlet oxygen radical (1O2) plays an important role. The obtained results point out that MB degradation by nano-sized β-MnO2 is due to the catalytic oxidation of H2O2 on β-MnO2surface reactive sites, rather than surface oxidation or adsorption. The reusability of nano-sized β-MnO2 was also examined after five times of recycling to evaluate the applicability of β-MnO2 for wastewater treatment.

Fabrication of 3D structured ZnO nanorod/reduced graphene oxide hydrogels and their use for photo-enhanced organic dye removal

Luan, Van Hoang,Tien, Huynh Ngoc,Hur, Seung Hyun Elsevier 2015 JOURNAL OF COLLOID AND INTERFACE SCIENCE - Vol.437 No.-

<P><B>Abstract</B></P> <P>Hybrid 3-dimensional (3D) structures composed of zinc oxide (ZnO) nanorods and reduced graphene oxide hydrogel (rGOH) were fabricated by chemical reaction between Zn ions and GO followed by <I>in-situ</I> lateral growth of ZnO nanorods using Zn ions as seed points. The 3D networked ZnO nanorod–rGOH (ZNR–rGOH) fabricated in this study exhibited excellent methylene blue (MB) removal efficiency due to efficient physical adsorption of dye molecules because of electrostatic attractive forces and enhanced photocatalytic activity by the laterally grown ZnO nanorods. The Langmuir–Hinshelwood rate constant of ZNR–rGOH was 4-fold higher than that of pristine rGO due to the enhanced photocatalytic effects obtained by incorporating laterally grown ZnO nanorods inside the rGOH network.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The Covalently-bonded 3D networked graphene hydrogel was fabricated using Zn ions. </LI> <LI> ZnO nanorods were laterally grown inside rGOH networks using hydrothermal synthesis. </LI> <LI> Dye removal efficiency was highly enhanced by using hybrid structures. </LI> <LI> Visible light photocatalytic activity was also observed in the hybrid structures. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Oxidative Degradation of a Pharmaceutical by Carbocatalysts: Radical versus non-Radical Pathways

Van Luan PHAM,Do Gun KIM,Seok Oh KO 대한환경공학회 2019 대한환경공학회 학술발표논문집 Vol.2019 No.-

Enhanced capacitance of three dimensional graphene oxide hydrogel and silver nanowire hybrid structures

Van Hoang LUAN,Miri SEO,Yiseul SONG,Seung Hyun HUR 한국진공학회 2016 한국진공학회 학술발표회초록집 Vol.2016 No.8

Enhanced Capacitance of Three Dimensional Graphene Oxide Hydrogel by the Hybridization with Silver Nanowire

Luan, Van Hoang,Son, Hye Jeong,Chung, Jin Suk,Hur, Seung Hyun American Scientific Publishers 2017 Journal of Nanoscience and Nanotechnology Vol.17 No.10

<P>Herein, a three-dimensional (3D) reduced graphene oxide hydrogel (rGOH) was fabricated by crosslinking ethylene diamine (EDA) and the functional groups of GO in the presence of one-dimensional (1D) Ag nanowires (NWs). The Ag NWs increased the electrical conductivity and the pore size of the final 3D structures. The capacitance of Ag-rGOH (369 F g(-1)) was 1.7 times higher than that of EDA-rGOH (218 F g(-1)) and 1.3 times higher than that of a physically mixed sample with the same Ag content. Moreover, the Ag-rGOH electrode also exhibits excellent long-term stability with a capacitance retention of more than 90% over 1,000 cycles and a high energy of 2.2 Wh kg(-1) at 900 W kg(-1).</P>

Mussel-inspired dopamine-mediated graphene hybrid with silver nanoparticles for high performance electrochemical energy storage electrodes

Luan, Van Hoang,Bae, Daeryeong,Han, Jong Hun,Lee, Wonoh Elsevier 2018 Composites Part B, Engineering Vol.134 No.-

<P><B>Abstract</B></P> <P>To facilitate the immobilization of the silver nanoparticles with high crystallinity and stability, the mussel-inspired dopamine is functionalized on the surface of the graphene. Considering the unique adhesive property of a catechol group in the dopamine toward metallic ions, a large amount of silver nanoparticles can be coated on the surface of the dopamine-functionalized graphene. To use the high surface area of graphene, large-sized graphene sheets are prepared using the microwave heat treatment of graphite powder followed by chemical oxidation and exfoliation. In addition, the large-area graphene sheets are selectively collected by a pH-assisted fractionation technique and are confirmed by the green-light filtered optical microscopic images. The dopamine-mediated graphene hybrid with silver nanoparticles shows superior electrochemical activity with enhanced electrical conductivity by promoting the decoration of stable silver nanoparticles on the surface of graphene. The resulting hybrid exhibits 7.6 times and 1.6 times higher electrochemical capacitance than that of the bare and graphene/silver hybrid-modified glassy carbon electrodes, respectively.</P>

Highly porous and capacitive copper oxide nanowire/graphene hybrid carbon nanostructure for high-performance supercapacitor electrodes

Luan, Van Hoang,Han, Jong Hun,Kang, Hyun Wook,Lee, Wonoh Elsevier Science Ltd 2019 Composites Part B, Engineering Vol.178 No.-

<P><B>Abstract</B></P> <P>Three-dimensionally porous carbon nanostructures have been widely used in energy storage applications owing to their large specific surface areas and excellent electrical properties. In addition, copper oxide has been considered as an effective pseudocapacitive material to significantly increase the energy density. In this paper, we introduce the synergetic combination of one-dimensional copper oxide nanowires and two-dimensional graphene sheets to fabricate a highly porous and electrically conductive three-dimensional hybrid nanostructure for high-performance supercapacitor electrodes with increased capacitances. The copper oxide nanowires were synthesized by reduction of copper nitrate and sequential oxidation at a high temperature. The copper oxide nanowire/graphene hybrid three-dimensional nanostructure was obtained by a self-assembly technique through a simple hydrothermal treatment. The hybrid nanostructure had an acceptable surface area and increased thermal stability. The porous hybrid nanostructure utilized as a supercapacitor electrode provided 1.6 times higher electrochemical capacitance than that of a graphene-only nanostructure-based electrode as well as superior capacitance stability with a retention of 91.2% retention after 5,000 charge−discharge cycles. Owing to the increased capacitance, the manufactured electrode exhibited high a specific energy density of 50.6 Wh kg<SUP>−1</SUP> at a power density of 200 W kg<SUP>−1</SUP>, which demonstrates its potential for use in electrochemical energy storage devices.</P>

The Multidimensional Masculinity in Nguyễn Huy Thiệp’s Short Stories

( Van Thuan Nguyen ),( Anh Dan Nguyen ),( Van Luan Nguyen ) 부산외국어대학교 아세안연구원 2024 Suvannabhumi Vol.16 No.1

Nguyễn Huy Thiệp is a pillar in Vietnamese cultural life after the Second Indochina War, and the fates of men and women at the beginning of Đổi mới (Renovation) is one of the prominent themes in his short stories. To show off sexual power, seek glory, and maintain his dominant position, Thiệp’s heroes engage in a game of oppressing the weak, hunting animals, and harassing women. However, due to the complex changes in social life, moral values, and gender inequality, men in the postwar period quickly experienced the feeling of humiliation, impotence, and failure. In turn, the sophisticated aspects of masculinity demonstrate the cultural and ethical concerns of contemporary Vietnamese society. By exploring the multidimensional nature of masculinity expressed in Thiệp’s stories, this study aims to resolve misconceptions about gender and the relationship between men and women in his work.

Oxidative degradation of the antibiotic oxytetracycline by Cu@Fe₃O₄ core-shell nanoparticles

Pham, Van Luan,Kim, Do-Gun,Ko, Seok-Oh Elsevier 2018 The Science of the total environment Vol.631 No.-

<P><B>Abstract</B></P> <P>A core-shell nanostructure composed of zero-valent Cu (core) and Fe<SUB>3</SUB>O<SUB>4</SUB> (shell) (Cu@Fe<SUB>3</SUB>O<SUB>4</SUB>) was prepared by a simple reduction method and was evaluated for the degradation of oxytetracycline (OTC), an antibiotic. The Cu core and the Fe<SUB>3</SUB>O<SUB>4</SUB> shell were verified by X-ray diffractometry (XRD) and transmission electron microscopy. The optimal molar ratio of [Cu]/[Fe] (1/1) in Cu@Fe<SUB>3</SUB>O<SUB>4</SUB> created an outstanding synergic effect, leading to >99% OTC degradation as well as H<SUB>2</SUB>O<SUB>2</SUB> decomposition within 10min at the reaction conditions of 1g/L Cu@Fe<SUB>3</SUB>O<SUB>4</SUB>, 20mg/L OTC, 20mM H<SUB>2</SUB>O<SUB>2</SUB>, and pH3.0 (and even at pH9.0). The OTC degradation rate by Cu@Fe<SUB>3</SUB>O<SUB>4</SUB> was higher than obtained using single nanoparticle of Cu or Fe<SUB>3</SUB>O<SUB>4</SUB>. The results of the study using radical scavengers showed that OH is the major reactive oxygen species contributing to the OTC degradation. Finally, good stability, reusability, and magnetic separation were obtained with approximately 97% OTC degradation and no notable change in XRD patterns after the Cu@Fe<SUB>3</SUB>O<SUB>4</SUB> catalyst was reused five times. These results demonstrate that Cu@Fe<SUB>3</SUB>O<SUB>4</SUB> is a novel prospective candidate for the pharmaceutical and personal care products degradation in the aqueous phase.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Cu@Fe<SUB>3</SUB>O<SUB>4</SUB> core-shell nanostructure was synthesized by a simple reduction method. </LI> <LI> The optimal moles ratio of [Cu]/[Fe] in Cu@Fe<SUB>3</SUB>O<SUB>4</SUB> was found is 1/1. </LI> <LI> Cu@Fe<SUB>3</SUB>O<SUB>4</SUB> shows superior catalytic activity than the single Cu NPs and Fe<SUB>3</SUB>O<SUB>4</SUB> NPs. </LI> <LI> Cu@Fe<SUB>3</SUB>O<SUB>4</SUB> possesses less pH dependent and maintain high activity even at pH=9.0. </LI> <LI> Cu NPs was major contributed in the Cu@Fe<SUB>3</SUB>O<SUB>4</SUB>/H<SUB>2</SUB>O<SUB>2</SUB> system for OTC degradation. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>