http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
THALLIUM-201 PER-RECTAL SCINTIGRAPHY FOR EVALUATING PORTAL CIRCULATION AFTER TREATMENT
Nakajima, Kenichi,Tonami, Norihisa,Watanabe, Naoto,Yokoyama, Kunihiko,Seto, Mikito,Seki, Hiroyasu,Takayama, Teruhiko,Koizumi, Kiyoshi,Kanai, Kinichi Hisada Masanobu,Hinoue, Yoshinobu,Kobayashi, Yashir 대한핵의학회 1984 핵의학 분자영상 Vol.18 No.1
MRI Reveals Edema in Larynx (But Not in Brain) During Anaphylactic Hypotension in Anesthetized Rats
Ichiro Toyota,Mamoru Tanida,Toshishige Shibamoto,Mofei Wang,Yasutaka Kurata,Hisao Tonami 대한천식알레르기학회 2013 Allergy, Asthma & Immunology Research Vol.5 No.6
Purpose: Anaphylactic shock is sometimes accompanied by local interstitial edema due to increased vascular permeability. We performed magneticresonance imaging (MRI) to compare edema in the larynx and brain of anesthetized rats during anaphylactic hypotension versus vasodilator-inducedhypotension. Methods: Male Sprague Dawley rats were subjected to hypotension induced by the ovalbumin antigen (n=7) or a vasodilator sodiumnitroprusside (SNP; n=7). Apparent diffusion coefficient (ADC) and T2-relaxation time (T2RT) were quantified on MRI performed repeatedly for upto 68 min after the injection of either agent. The presence of laryngeal edema was also examined by histological examination. Separately, the occurrenceof brain edema was assessed by measuring brain water content using the wet/dry method in rats with anaphylaxis (n=5) or SNP (n=5) andthe non-hypotensive control rats (n=5). Mast cells in hypothalamus were morphologically examined. Results: Mean arterial blood pressure similarlydecreased to 35 mmHg after an injection of the antigen or SNP. Hyperintensity on T2-weighted images (as reflected by elevated T2RT) was foundin the larynx as early as 13 min after an injection of the antigen, but not SNP. A postmortem histological examination revealed epiglottic edema inthe rats with anaphylaxis, but not SNP. In contrast, no significant changes in T2RT or ADC were detectable in the brains of any rats studied. In separateexperiments, the quantified brain water content did not increase in either anaphylaxis or SNP rats, as compared with the non-hypotensive controlrats. The numbers of mast cells with metachromatic granules in the hypothalamus were not different between rats with anaphylaxis and SNP,suggesting the absence of anaphylactic reaction in hypothalamus. Conclusion: Edema was detected using the MRI technique in the larynx duringrat anaphylaxis, but not in the brain.