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Tongsong, Theera,Tinnangwattana, Dangcheewan,Vichak-ururote, Linlada,Tontivuthikul, Paponrad,Charoenratana, Cholaros,Lerthiranwong, Thitikarn Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.9
Background: To compare diagnostic performance in differentiating benign from malignant ovarian masses between IOTA (the International Ovarian Tumor Analysis) simple rules and subjective sonographic assessment. Materials and Methods: Women scheduled for elective surgery because of ovarian masses were recruited into the study and underwent ultrasound examination within 24 hours of surgery to apply the IOTA simple rules by general gynecologists and to record video clips for subjective assessment by an experienced sonographer. The diagnostic performance of the IOTA rules and subjective assessment for differentiation between benign and malignant masses was compared. The gold standard diagnosis was pathological or operative findings. Results: A total of 150 ovarian masses were covered, comprising 105 (70%) benign and 45 (30%) malignant. Of them, the IOTA simple rules could be applied in 119 (79.3%) and were inconclusive in 31 (20.7%) whereas subjective assessment could be applied in all cases (100%). The sensitivity and the specificity of the IOTA simple rules and subjective assessment were not significantly different, 82.9% vs 86.7% and 94.0% vs 94.3% respectively. The agreement of the two methods in prediction was high with a Kappa index of 0.835. Conclusions: Both techniques had a high diagnostic performance in differentiation between benign and malignant ovarian masses but the IOTA rules had a relatively high rate of inconclusive results. The IOTA rules can be used as an effective screening technique by general gynecologists but when the results are inconclusive they should consult experienced sonographers.
Diagnosis of Diabetic Retinopathy Using Face-Recognition Techniques
Luis Frazao,Nipon Theera-Umpon,Sansanee Auephanwiriyakul 한국재활복지공학회 2016 한국재활복지공학회 학술대회논문집 Vol.2016 No.11
An automatic diagnostic system to detect diabetic retinopathy in 1200 eye color fundus images from the popular Messidor database was developed with promising results. The innovative methodology was inspired by techniques usually applied in the field of face recognition, namely the Principal Component Analysis (PCA) and the Independent Component Analysis (ICA). The analysis of local retinal features (exudates and red lesions) in addition to the holistic texture features analyzed in this work is expected to improve the system performance.
IOTA Simple Rules in Differentiating between Benign and Malignant Ovarian Tumors
Tantipalakorn, Charuwan,Wanapirak, Chanane,Khunamornpong, Surapan,Sukpan, Kornkanok,Tongsong, Theera Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.13
Background: To evaluate the diagnostic performance of IOTA simple rules in differentiating between benign and malignant ovarian tumors. Materials and Methods: A study of diagnostic performance was conducted on women scheduled for elective surgery due to ovarian masses between March 2007 and March 2012. All patients underwent ultrasound examination for IOTA simple rules within 24 hours of surgery. All examinations were performed by the authors, who had no any clinical information of the patients, to differentiate between benign and malignant adnexal masses using IOTA simple rules. Gold standard diagnosis was based on pathological or operative findings. Results: A total of 398 adnexal masses, in 376 women, were available for analysis. Of them, the IOTA simple rules could be applied in 319 (80.1%) including 212 (66.5%) benign tumors and 107 (33.6%) malignant tumors. The simple rules yielded inconclusive results in 79 (19.9%) masses. In the 319 masses for which the IOTA simple rules could be applied, sensitivity was 82.9% and specificity 95.3%. Conclusions: The IOTA simple rules have high diagnostic performance in differentiating between benign and malignant adnexal masses. Nevertheless, inconclusive results are relatively common.