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Nobuhiko Henmi,Yuta Sumi,Michihiko Tanaka 대한기계학회 2010 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.24 No.1
A displacement magnification mechanism which uses flexure motion guide using elastic hinges can realize smooth frictionless motion but has poor vibration damping capability. An impact damper is a damping mechanism which uses collision energy to dissipate vibration energy. If the damper is used for vibration control of the flexure mechanism, it may be able to dissipate unexpected vibration without killing the merits of the flexure mechanism. In the paper, a loading type impact damper is applied to settle down transient vibration of a displacement magnification mechanism. We investigate differences of damping effect by setting conditions of the damper. It is shown that the impact damper can eliminate residual vibration at step response effectively without steady state error. The experimental displacement magnification mechanism with impact damper can settle down less than 1/5 of the response without the damper under appropriate setting conditions. Influence of natural frequency ratio between damper and displacement magnification mechanism is investigated. Influences of indentation at impact point are also examined.
An Open-Loop Method for Point-to-Point Positioning of a Piezoelectric Actuator
Nobuhiko Henmi,Michihiko Tanaka 한국정밀공학회 2007 International Journal of Precision Engineering and Vol.8 No.2
We describe how to control a piezoelectric actuator using the open-loop method for point-to-point positioning. Since piezoelectric actuators have nonlinear characteristics due to hysteresis and creep between the input voltage and the resulting displacement, a special method is required to eliminate this nonlinearity for an open-loop drive. We have introduced open-loop driving methods for piezoelectric actuators in the past, which required a large input voltage and an initializing motion sequence to reset the state of the actuator before each movement. In this paper, we propose a new driving method that uses the initializing state. This method also utilizes the overshoot from both the upward and downward stepwise drives. Applying this method, we obtained precise point-to-point positioning without the influence of hysteresis and creep.
An Open-Loop Method for Point-to-Point Positioning of a Piezoelectric Actuator
Henmi, Nobuhiko,Tanaka, Michihiko Korean Society for Precision Engineering 2007 International Journal of Precision Engineering and Vol.8 No.2
We describe how to control a piezoelectric actuator using the open-loop method for point-to-point positioning. Since piezoelectric actuators have nonlinear characteristics due to hysteresis and creep between the input voltage and the resulting displacement, a special method is required to eliminate this nonlinearity for an open-loop drive. We have introduced open-loop driving methods for piezoelectric actuators in the past, which required a large input voltage and an initializing motion sequence to reset the state of the actuator before each movement. In this paper, we propose a new driving method that uses the initializing state. This method also utilizes the overshoot from both the upward and downward stepwise drives. Applying this method., we obtained precise point-to-point positioning without the influence of hysteresis and creep.
Ken Yoshida,Hideya Yamazaki,Satoaki Nakamura,Koji Masui,Tadayuki Kotsuma,Hironori Akiyama,Eiichi Tanaka,Nobuhiko Yoshikawa,Yasuo Uesugi,Taiju Shimbo,Yoshifumi Narumi,Yasuo Yoshioka 대한부인종양학회 2015 Journal of Gynecologic Oncology Vol.26 No.3
Objective: To assess actual rates of late vaginal stenosis and identify predisposing factors for complications among patients with previously untreated cervical cancer following high-dose-rate brachytherapy. Methods: We performed longitudinal analyses of 57 patients using the modified Dische score at 6, 12, 18, 24, 36, and 60 months after treatment, which consisted of 15 interstitial brachytherapys and 42 conventional intracavitary brachytherapys, with a median follow-up time of 36 months (range, 6 to 144 months). Results: More than half of the patients developed grade 1 (mild) vaginal stenosis within the first year of follow-up, and grade 2 (97.5%, moderate) to grade 3 (severe) stenosis gradually increased with time. Actual stenosis rates for grade 1, 2, and 3 were 97.5% (95% confidence interval [CI], 92.7 to 97.5), 60.7% (95% CI, 42.2 to 79.3), and 7.4% (95% CI, 0 to 18.4) at 3 years after treatment. Pallor reaction grade 2–3 at 6 months was only a statistically significant predisposing factor for grade 2–3 late vaginal stenosis 3 years or later with a hazard ratio of 3.48 (95% CI, 1.32 to 9.19; p=0.018) by a multivariate Cox proportional hazard model. Patients with grade 0–1 pallor reaction at 6 months showed a grade ≥2 vaginal stenosis rate of 53%, whereas the grade 2–3 pallor reaction group achieved a grade ≥2 vaginal stenosis rate at 3 years at 100% (p=0.001). Conclusion: High-dose-rate brachytherapy was associated with high incidence of late vaginal stenosis. Pallor reaction grade 2–3 at 6 months was predictive of late grade 2–3 vaginal stenosis at 3 years after treatment. These findings should prove helpful for patient counseling and preventive intervention.
Masuya Hiroshi,Usuda Daiki,Nakata Hatsumi,Yuhara Naomi,Kurihara Keiko,Namiki Yuri,Iwase Shigeru,Takada Toyoyuki,Tanaka Nobuhiko,Suzuki Kenta,Yamagata Yuki,Kobayashi Norio,Yoshiki Atsushi,Kushida Tatsu 한국실험동물학회 2021 Laboratory Animal Research Vol.37 No.1
Online databases are crucial infrastructures to facilitate the wide effective and efficient use of mouse mutant resources in life sciences. The number and types of mouse resources have been rapidly growing due to the development of genetic modification technology with associated information of genomic sequence and phenotypes. Therefore, data integration technologies to improve the findability, accessibility, interoperability, and reusability of mouse strain data becomes essential for mouse strain repositories. In 2020, the RIKEN BioResource Research Center released an integrated database of bioresources including, experimental mouse strains, Arabidopsis thaliana as a laboratory plant, cell lines, microorganisms, and genetic materials using Resource Description Framework-related technologies. The integrated database shows multiple advanced features for the dissemination of bioresource information. The current version of our online catalog of mouse strains which functions as a part of the integrated database of bioresources is available from search bars on the page of the Center ( https://brc.riken.jp ) and the Experimental Animal Division ( https://mus.brc.riken.jp/ ) websites. The BioResource Research Center also released a genomic variation database of mouse strains established in Japan and Western Europe, MoG + ( https://molossinus.brc.riken.jp/mogplus/ ), and a database for phenotype-phenotype associations across the mouse phenome using data from the International Mouse Phenotyping Platform. In this review, we describe features of current version of databases related to mouse strain resources in RIKEN BioResource Research Center and discuss future views.