In-line Automatic Defect Repair System for TFT-LCD Production

Arai, Takeshi,Nakasu, Nobuaki,Yoshimura, Kazushi,Edamura, Tadao The Korean Infomation Display Society 2009 Journal of information display Vol.10 No.4

An automated circuit repair system was developed for enhancing the yield of nondefective liquid crystal panels, focusing on the resist patterns on the circuit material layer of thin-film transistor (TFT) substrates prior to etching. The developed system has an advantage over the parallel conventional system: In the former, the repair conditions depend on the type of resist whereas in the latter, the repair parameters must be fine-tuned for each circuit material. The developed system consists of a resist pattern defect inspection system and a pattern repair system for short and open defects. The repair system performs fine corrections of abnormal areas of the resist pattern. The open-repair system is equipped with a syringe to dispense resist. To maintain a stable resist diameter, a thermal insulator was installed in the syringe system. As a result, the diameter of the dispensed resist became much more stable than when no thermal insulator was used. The resist diameter was kept within the target of $400{\pm}100{\mu}m$. Furthermore, a prototype system was constructed, and using a dummy pattern, it was confirmed that the system worked automatically and correctly.

In-line Automatic Defect Repair System for TFT-LCD Production

Takeshi Arai,Nobuaki Nakasu,Kazushi Yoshimura,Tadao Edamura 한국정보디스플레이학회 2009 Journal of information display Vol.10 No.4

An automated circuit repair system was developed for enhancing the yield of nondefective liquid crystal panels, focusing on the resist patterns on the circuit material layer of thin-film transistor (TFT) substrates prior to etching. The developed system has an advantage over the parallel conventional system: In the former, the repair conditions depend on the type of resist whereas in the latter, the repair parameters must be fine-tuned for each circuit material. The developed system consists of a resist pattern defect inspection system and a pattern repair system for short and open defects. The repair system performs fine corrections of abnormal areas of the resist pattern. The open-repair system is equipped with a syringe to dispense resist. To maintain a stable resist diameter, a thermal insulator was installed in the syringe system. As a result, the diameter of the dispensed resist became much more stable than when no thermal insulator was used. The resist diameter was kept within the target of 400±100 µm. Furthermore, a prototype system was constructed, and using a dummy pattern, it was confirmed that the system worked automatically and correctly.

Reflux-related Extraesophageal Symptoms Until Proven Otherwise: A Direct Measurement of Abnormal Proximal Exposure Based on Hypopharyngeal Multichannel Intraluminal Impedance as a Reliable Indicator for Successful Treatment Outcomes

( Takeshi Suzuki ),( Yosuke Seki ),( Tomoaki Matsumura ),( Makoto Arai ),( Toyoyuki Hanazawa ),( Yoshitaka Okamoto ),( Haruhiko Suzuki ),( Kazunori Kasama ),( Akiko Umezawa ),( Yoshimoti Kurokawa ),( 대한소화기기능성질환·운동학회 2022 Journal of Neurogastroenterology and Motility (JNM Vol.28 No.1

Background/Aims The Lyon Consensus defined parameters based on upper endoscopy and 24-hour combined multichannel intraluminal impedancepH (MII-pH), that conclusively establish the presence of gastroesophageal reflux disease (GERD). However, the true role of upper endoscopy and MII-pH to evaluate patients with extraesophageal symptoms (EES) has not been well established. Hypopharyngeal MII (HMII), which directly measures laryngopharyngeal reflux (LPR) events, has been utilized to evaluate patients with EES suggestive of LPR. Methods This was a retrospective study involving patients with EES for > 12 weeks despite proton pump inhibitor therapy, and had no endoscopic confirmatory evidence for GERD and negative MII-pH. All patients were subsequently referred for further evaluation of EES with “unknown” etiology and underwent laryngoscopy and HMII. Based on HMII, abnormal proximal exposure (APE) was defined as LPR ≥ 1/day and/or full column reflux (reflux 2 cm distal to the upper esophageal sphincter) > 4/day. Patients with APE were offered antireflux surgery (ARS) and the outcome of ARS was objectively assessed using Reflux Symptom Index. Results Of 21 patients with EES which was thought to be GERD-unrelated based on endoscopy and MII-pH, 17 patients (81%) had APE. Eight patients with APE who had undergone ARS had significant symptomatic improvement in the Reflux Symptom Index score (19.6 ± 4.9 pre-ARS to 5.8 ± 1.4 post-ARS, P = 0.008). Conclusions A conventional diagnostic approach using endoscopy and MII-pH may not be sufficient to evaluate patients with EES suggestive of LPR. HMII is essential to evaluate patients with EES, and APE could be a reliable indicator for successful treatment outcomes. (J Neurogastroenterol Motil 2022;28:69-77)

Clinical Incidence of Sacroiliac Joint Arthritis and Pain after Sacropelvic Fixation for Spinal Deformity

Seiji Ohtori,Takeshi Sainoh,Masashi Takaso,Gen Inoue,Sumihisa Orita,Yawara Eguchi,Junichi Nakamura,Yasuchika Aoki,Tetsuhiro Ishikawa,Masayuki Miyagi,Gen Arai,Hiroto Kamoda,Miyako Suzuki,Gou Kubota,Yos 연세대학교의과대학 2012 Yonsei medical journal Vol.53 No.2

Purpose: Sacroiliac fixation using iliac screws for highly unstable lumbar spine has been reported with an improved fusion rate and clinical results. On the other hand, there is a potential for clinical problems related to iliac fixation, including late sacroiliac joint arthritis and pain. Materials and Methods: Twenty patients were evaluated. Degenerative scoliosis was diagnosed in 7 patients, failed back syndrome in 6 patients, destructive spondyloarthropathy in 4 patients, and Charcot spine in 3 patients. All patients underwent posterolateral fusion surgery incorporating lumbar, S1 and iliac screws. We evaluated the pain scores, bone union, and degeneration of sacroiliac joints by X-ray imaging and computed tomography before and 3 years after surgery. For evaluation of low back and buttock pain from sacroiliac joints 3 years after surgery, lidocaine was administered in order to examine pain relief thereafter. Results: Pain scores significantly improved after surgery. All patients showed bone union at final follow-up. Degeneration of sacroiliac joints was not seen in the 20 patients 3 years after surgery. Patients showed slight low back and buttock pain 3 years after surgery. However, not all patients showed relief of the low back and buttock pain after injection of lidocaine into the sacroiliac joint, indicating that their pain did not originate from sacroiliac joints. Conclusion: The fusion rate and clinical results were excellent. Also, degeneration and pain from sacroiliac joints were not seen within 3 years after surgery. We recommend sacroiliac fixation using iliac screws for highly unstable lumbar spine.

An SOFC Cathode Composed of LaNi0.6Fe0.4O3 and Ce(Ln)O2 (Ln=Sm, Gd, Pr)

Reiichi Chiba,Takeshi Komatsu,Himeko Orui,Hiroaki Taguchi,Kazuhiko Nozawa,Hajime Arai 한국세라믹학회 2008 한국세라믹학회지 Vol.45 No.12

We fabricated single cells with a cathode consisting of a LaNi0.6Fe0.4O3-Ce0.8Sm0.2O1.9 composite (LNF-S20DC composite) active layer and an LNF current collecting layer on a 0.89ZrO2-0.10Sc2O3 -0.01Al2O3 electrolyte sheet. The cathode layers were prepared by the screen-printing method. The cathode properties of these cells were measured by the AC impedance method at 800oC. The cathodes with the ceria-LNF composite active layer exhibited high power performance prior to current loading. We investigated the influence of the mixture ratio of LNF and S20DC on the cathodes properties. The Sm in the ceria particles of the composite cathode was substituted with other rare-earth elements. Cathodes with Pr and Gd co-doped ceria in the active layer provided the better performance than those with Sm- or Gd-doped ceria. We fabricated single cells with a cathode consisting of a LaNi0.6Fe0.4O3-Ce0.8Sm0.2O1.9 composite (LNF-S20DC composite) active layer and an LNF current collecting layer on a 0.89ZrO2-0.10Sc2O3 -0.01Al2O3 electrolyte sheet. The cathode layers were prepared by the screen-printing method. The cathode properties of these cells were measured by the AC impedance method at 800oC. The cathodes with the ceria-LNF composite active layer exhibited high power performance prior to current loading. We investigated the influence of the mixture ratio of LNF and S20DC on the cathodes properties. The Sm in the ceria particles of the composite cathode was substituted with other rare-earth elements. Cathodes with Pr and Gd co-doped ceria in the active layer provided the better performance than those with Sm- or Gd-doped ceria.

Tester Structure Expression Language and Its Application to the Environment for VLSI Tester Program Development

Sato, Masayuki,Wakamatsu, Hiroki,Arai, Masayuki,Ichino, Kenichi,Iwasaki, Kazuhiko,Asakawa, Takeshi Korea Information Processing Society 2008 Journal of information processing systems Vol.4 No.4

VLSI chips have been tested using various automatic test equipment (ATE). Although each ATE has a similar structure, the language for ATE is proprietary and it is not easy to convert a test program for use among different ATE vendors. To address this difficulty we propose a tester structure expression language, a tester language with a novel format. The developed language is called the general tester language (GTL). Developing an interpreter for each tester, the GTL program can be directly applied to the ATE without conversion. It is also possible to select a cost-effective ATE from the test program, because the program expresses the required ATE resources, such as pin counts, measurement accuracy, and memory capacity. We describe the prototype environment for the GTL and the tester selection tool. The software size of the prototype is approximately 27,800 steps and 15 manmonths were required. Using the tester selection tool, the number of man-hours required in order to select an ATE could be reduced to 1/10. A GTL program was successfully executed on actual ATE.

Prognostication of early-onset endometrioid endometrial cancer based on genome-wide DNA methylation profiles

Takuro Hirano,Eri Arai,Mao Fujimoto,Yuji Nakayama,Ying Tian,Nanako Ito,Takeshi Makabe,Wataru Yamagami,Nobuyuki Susumu,Daisuke Aoki,Yae Kanai 대한부인종양학회 2022 Journal of Gynecologic Oncology Vol.33 No.6

Objective: The aim of this study was to establish criteria that would indicate whether fertility preservation therapy would likely be safe for patients aged 40 years or less with endometrioid endometrial cancer based on their DNA methylation profile. Methods: Forty-nine fresh-frozen tissue samples from patients with endometrial cancer from an initial cohort and 31 formalin-fixed paraffin-embedded tissue samples from a second cohort were subjected to genome-wide DNA methylation analysis using the Infinium MethylationEPIC BeadChip. Results: Epigenomic clustering of early-onset endometrial cancer was correlated with the widely used recurrence risk classification. Genes showing differences in DNA methylation levels between the low-recurrence-risk category and intermediate- and high-risk categories were accumulated in pathways related to fibroblast growth factor and nuclear factor-κB signaling. DNA hypomethylation and overexpression of were frequently observed in the low-risk category. Eight hundred thirty-one marker CpG probes showed area under the curve values of >0.7 on the receiver operating characteristic curve for discrimination of patients belonging to the low-risk category. By combining marker CpG sites, seven panels for placing patients into the low-risk category with 91.3% or more sensitivity and specificity in both the initial and second cohorts were established. Conclusions: DNA methylation diagnostics criteria using up to 6 of 8 CpG sites for ,and may be applicable to recurrence risk,,,,estimation for patients aged 40 years or less with endometrial cancer, regardless of tumor cell content, even if formalin-fixed paraffin-embedded biopsy or curettage materials are used.

An SOFC Cathode Composed of LaNi_0.6Fe_0.4O₃ and Ce(Ln)O₂ (Ln=Sm, Gd, Pr)

Chiba, Reiichi,Komatsu, Takeshi,Orui, Himeko,Taguchi, Hiroaki,Nazawa, Kazuhiko,Arai, Hajime The Korean Ceramic Society 2008 한국세라믹학회지 Vol.45 No.12

We fabricated single cells with a cathode consisting of a $LaNi_{0.6}Fe_{0.4}O_3-Ce_{0.8}Sm_{0.2}O_{1.9}$ composite (LNF-S20DC composite) active layer and an LNF current collecting layer on a ${0.89ZrO_2}-{0.10Sc_2}{O_3}-0.01{Al_2}{O_3}$ electrolyte sheet. The cathode layers were prepared by the screen-printing method. The cathode properties of these cells were measured by the AC impedance method at $800^{\circ}C$. The cathodes with the ceria-LNF composite active layer exhibited high power performance prior to current loading. We investigated the influence of the mixture ratio of LNF and S20DC on the cathodes properties. The Sm in the ceria particles of the composite cathode was substituted with other rare-earth elements. Cathodes with Pr and Gd co-doped ceria in the active layer provided the better performance than those with Sm- or Gd-doped ceria.

A Case of a Meningeal Carcinomatosis of the Internal Auditory Meatus Treated as Sudden Deafness

Fumiyuki Goto,Miki Arai,Takeshi Wakabayashi,Tomoko Otomo,Ryoto Nagai,Shuujiro Minami,Takanobu Shimada,Masato Fujii 대한평형의학회 2015 Research in Vestibular Science Vol.14 No.4

We describe a case of meningeal carcinomatosis of the internal auditory meatus presenting as sudden deafness accompanied by dizziness. A 54-year-old woman complained of acute right-side hearing loss in October 2014. The pure tone audiometry test revealed right-side hearing loss of 47.5 dB. She was treated with oral steroids. Her hearing as well as her symptoms of dizziness worsened and she was admitted for further examination. Her right and left-side hearing had worsened to 105.0 dB and 47.5 dB, respectively. A magnetic resonance imaging scan of the head revealed bilateral enhancement of the internal auditory canal and multiple brain metastases. The chest radiograph revealed a mass in the left lung. Adenocarcinoma of the lung was diagnosed. Lumbar puncture yielded no evidence of carcinoma cells in the cerebrospinal fluid, but an increased number of lymphocytes was confirmed. A diagnosis of multiple brain metastases and leptomeningeal metastasis from the adenocarcinoma of the lung was considered. Whole-brain radiation therapy (30 Gr/10 fractions) was administered. Progressive bilateral hearing loss is a rare first manifestation of meningeal carcinomatosis. It is quite important to consider the possibility of this condition when patients present with sudden deafness.Res Vestib Sci 2015;14(4):139-142

Multiple Shock Wave / Turbulent Boundary Layer Interactions and Turbulence Phenomena in a Supersonic Rectangular Duct

Hiromu Sugiyama,Takakage Arai,Takeshi Kagawa 대한기계학회 1998 KSME/JSME THERMAL and FLUID Engineering Conference Vol.1 No.1