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Hyun Jun Ahn,Jungmin Moon,Sungho Koh,Yujin Seo,Choong-Ki Kim,Il Cheol Rho,Choon Hwan Kim,Wan Sik Hwang,Byung Jin Cho Institute of Electrical and Electronics Engineers 2016 IEEE transactions on electron devices Vol. No.
<P>Erbium carbide (ErC<SUB>2</SUB>) prepared by atomic layer deposition (ALD) is successfully demonstrated for the first time as a novel work function (WF) metal for nMOSFET applications. The prepared ErC<SUB>2</SUB> shows a very low effective WF (eWF), as low as 3.9 eV on HfO<SUB>2</SUB>, yet with excellent thermal stability. In addition, it did not show significant Fermi-level pinning on high-k dielectrics even after high-temperature annealing. The low eWF property of ErC<SUB>2</SUB> originates from the properties of the lanthanide family, while its good thermal stability is attributed to the properties of metal carbides. ALD-ErC<SUB>2</SUB> has superior conformality over other deposition methods, and thus is a strong candidate for 3-D structure devices.</P>
임종호(Jongho Lim),조한슬(Hanseul Cho),고인석(Inseok Koh),서성호(Sungho Seo),유용재(Yongjae Yoo),최승문(Seungmoon Choi) 한국HCI학회 2017 한국HCI학회 학술대회 Vol.2017 No.2
본 연구에서는 정전기 촉감 디스플레이가 적용된 태블릿을 이용, 시각 장애인이 스스로 사진을 찍고 고대비 시각화 및 촉각의 다중감각으로 감상할 수 있는 시스템을 구현하였다. 태블릿 상의 어플리케이션으로 구현된 시스템은 촬영 보조와 감상의 두 가지 기능을 제공한다. 촬영 보조 기능은 피사체 (얼굴)을 추적하고, 피사체가 사진 중앙에 오도록 음성 안내를 통하여 유도한다. 감상기능에서는 사용자가 촬영한 사진을 윤곽선 추출 알고리즘을 이용하여 시각적으로는 고대비 변환된 이미지를 제공하며, 태블릿 화면상의 윤곽선 주변을 터치 시 정전기 진동촉감을 제공, 사진을 촉각적으로 만질 수 있도록 함으로써 시각 장애인들이 사진을 감상할 수 있도록 구현하였다.
Methylation quantitative trait loci analysis in Korean exposome study
Jaehyun Park,Sung Ok Kwon,San‑Ha Kim,Seung Jun Kim,Eun Jung Koh,Sungho Won,Woo Jin Kim,Seung Yong Hwang 대한독성 유전단백체 학회 2020 Molecular & cellular toxicology Vol.16 No.2
Background Environmental exposure and genotype variation influence DNA methylation. Studies on the effects of genotype variation were performed mainly on European ancestries. We analyzed the genetic effects on cord blood methylation of Koreans. Methods As part of the Korean Exposome study project, DNA was extracted from 192 cord blood samples for analysis. Cord blood samples were genotyped via Asian Precision Medicine Research Array analysis and methylation was measured using the Methylation EPIC Beadchip kits. The associations between genotypes and CpG methylation were analyzed with matrix eQTL. Results Conditional analysis revealed 34,425 methylation quantitative trait loci (mQTLs), and trans-mQTLs constituted 7.2% of all the associated CpG sites. About 80% of the total trans-associations were trans-chromosomal and the related SNPs were concentrated on chromosome 19. According to the results of DAVID, cis-mQTL-related SNPs resulting in amino acid substitutions were related to signal peptides or glycosylation. Conclusion We identified genotype variations associated with DNA methylation in the cord blood obtained from Koreans.