http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
SUGIYAMA, KOICHIRO,YONEKURA, YOSHINORI,MOTOGI, KAZUHITO,SAITO, YU,FUJISAWA, KENTA,ISHII, SHOTA,MOMOSE, MUNETAKE,HONMA, MAREKI,TAZAKI, FUMIE,TANAKA, KEI E.I.,HOSOKAWA, TAKASHI,UCHIYAMA, MIZUHO,INAYOSHI The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2
We have initiated single-dish monitoring observations of ~400 methanol maser sources at 6.7 GHz using the Hitachi 32-m radio telescope from December 2012 to systematically research periodic flux variations, which are observed in some methanol maser sources associated with high-mass (proto-)stars. In our monitoring, we have made daily monitoring, so that each source has been observed every nine days with an integration time of 5 min (typical $3{\sigma}$ detection sensitivities of 0.9 Jy). The monitoring observations help us statistically understand periodic flux variations with a period longer than 50 days. As an initial result, we present a new detection of periodic flux variations in the 6.7 GHz methanol maser source G 036.70+00.09. The period of the flux variations is ~53 days (~0.019 cycles $day^{-1}$), and seems to be stable over 9 cycles, at least until the middle of August 2014.
Prediction of Wear Depth Distribution by Slurry on a Pump Impeller
Sugiyama, Kenichi,Nagasaka, Hiroshi,Enomoto, Takeshi,Hattori, Shuji Korean Society for Fluid machinery 2009 International journal of fluid machinery and syste Vol.2 No.1
Slurry wear with sand particles in rivers is a serious problem for pump operation. Therefore, a technique to predict wear volume loss is required for selecting wear resistant materials and determining specifications for the maintenance period. This paper reports a method for predicting the wear depth distribution on the blade of an impeller. Slurry wear tests of an aluminum pump impeller were conducted. Prediction results of wear depth distribution approximately correspond with the results of slurry wear tests. This technique is useful for industrial application.
The Nutrition Assessment and Care for the Elderly in Japan
Sugiyama, Michiko,Nishimura, Akio,Koyama, Hideo Korean Society of Community Nutrition 2000 Journal of community nutrition Vol.2 No.1
In Japan, a new nursing insurance system was enforced in April 2000, where premiums were paid according to the level of necessary care. Our project, Nutrition Care and Management(NCM) for the elderly was started in 1995, funded by the Ministry of Health and Welfare of Japan. The NCM project was to provide appropriate nutrition care for the elderly and to see that it effectively functions as part of the health care services. There were 4 stages to the project : the first stage was to find out the PEM status among the elderly patients in hospital and home-care settings in Japan. The 2nd stage was to develop and evaluate nutritional assessment methods, anthropometry, resting energy expenditure measuring methods using of portable indirect calorimeter, and the convenient protein energy intake assessment methods, etc. for the elderly patients with PEM risk. The 3rd stage was to examine the effectiveness of the nutrition care plan induced of protein energy supplement and team care in improving nutrition among the elderly patients. The last stage was to develop the NCM set for the elderly patient based on the past three years of scientific evidence. it is expected that the NCM system for the elderly will provide adequate nutritional care management, improve the elderly care environment and create effective resource management.
Photocurrent attenuation by a single polar-to-nonpolar point mutation of channelrhodopsin-2
Sugiyama, Yuka,Wang, Hongxia,Hikima, Takuya,Sato, Minami,Kuroda, Jun,Takahashi, Tetsuo,Ishizuka, Toru,Yawo, Hiromu Korean Society of Photoscience 2009 Photochemical & photobiological sciences Vol.8 No.3
Channelrhodopsin-2 (ChR2), one of the algal light-gated cation channel rhodopsins, contains five peculiar glutamic acid residues in the N-terminal region corresponding to the second to third transmembrane helices. Here we made systematic mutations of these polar amino acid residues of ChR2 into nonpolar alanine, and evaluated their photocurrent properties. Amongst them, the photocurrent generated by the E97A mutation, ChR2(E97A), was much smaller than expected from its expression. The ChR2(E97A) photocurrent was similar to wild-type ChR2 in the kinetic profiles, the reversal potential and the dependency to the light power density. Our results suggest that the residue E97 is one of the molecular determinants involved in the ion flux regulation.
Ethnic Differences of two Non-synonymous Single Nucleotide Polymorphisms in CDA Gene
Sugiyama, E.,Lee, S.J.,Lee, S.S.,Kim, W.Y.,Kim, S.R.,Tohkin, M.,Hasegawa, R.,Okuda, H.,Kawamoto, M.,Kamatani, N.,Sawada, J.i.,Kaniwa, N.,Saito, Y.,Shin, J.G. 日本藥物動態學會 2009 DRUG METABOLISM AND PHARMACOKINETICS Vol.24 No.6
Cytidine deaminase, encoded by the CDA gene, catalyzes anti-cancer drugs gemcitabine and ara-C into their respective inactive metabolites. In CDA, two functionally significant non-synonymous polymorphisms, 79A>C (Lys27Gln) and 208G>A (Ala70Thr), have been found and their minor allele frequencies (MAFs) were reported in Japanese and Chinese patients and a relatively small numbers of healthy volunteers in Caucasians and Africans. In this study, we determined the MAFs of both polymorphisms in 200 healthy volunteers of Koreans, along with 206 Japanese, 200 Chinese-Americans, 150 Caucasian-Americans and 150 African-Americans to reveal ethnic differences. MAFs of 79A>C (Lys27Gln) were 0.153 in Koreans and 0.327 in Caucasian-Americans, 0.204 in Japanese, 0.155 in Chinese-Americans and 0.087 in African-Americans. MAFs of 208G>A (Ala70Thr) were 0.005 in Koreans and 0.022 in Japanese and the minor allele was not detected in Chinese-Americans, Caucasian-Americans or African-Americans. Thus possibly, MAF of 208G>A in Japanese is likely to be somewhat higher than in Koreans and Chinese-Americans. These data would provide fundamental and useful information for pharmacogenetic studies on cytidine deaminase-catalyzing drugs.
Sugiyama, Minetaka,Baek, Seong Yeol,Takashima, Shohei,Miyashita, Natsumi,Ishida, Kei,Mun, Jiyoung,Yeo, Soo-Hwan Elsevier 2018 Journal of bioscience and bioengineering Vol.126 No.6
<P>The yeast <I>Pichia kudriavzevii</I> N77-4 was isolated from the Korean traditional fermentation starter <I>nuruk</I>. In this study, fermentation performance and stress resistance ability of N77-4 was analyzed. N77-4 displayed superior thermotolerance (up to 44°C) in addition to enhanced acetic acid resistance compared to <I>Saccharomyces cerevisiae</I>. Moreover, N77-4 produced 7.4 g/L of ethanol with an overall production yield of 0.37 g/g glucose in 20 g/L glucose medium. However, in 250 g/L glucose medium the growth of N77-4 slowed down when the concentration of ethanol reached 14 g/L or more and ethanol production yield also decreased to 0.30 g/g glucose. An ethanol sensitivity test indicated that N77-4 was sensitive to the presence of 1% ethanol, which was not the case for <I>S. cerevisiae</I>. Furthermore, N77-4 displayed a severe growth defect in the presence of 6% ethanol. Because inositol biosynthesis is critical for ethanol resistance, expression levels of the <I>PkINO1</I> encoding a key enzyme for inositol biosynthesis was analyzed under ethanol stress conditions. We found that ethanol stress clearly repressed <I>PkINO1</I> expression in a dose-dependent manner and overexpression of <I>PkINO1</I> improved the growth of N77-4 by 19% in the presence of 6% ethanol. Furthermore, inositol supplementation also enhanced the growth by 13% under 6% ethanol condition. These findings indicate that preventing downregulation in <I>PkINO1</I> expression caused by ethanol stress improves ethanol resistance and enhances the utility of <I>P. kudriavzevii</I> N77-4 in brewing and fermentation biotechnology.</P>
Sugiyama, Masashi,Liu, Song,du Plessis, Marthinus Christoffel,Yamanaka, Masao,Yamada, Makoto,Suzuki, Taiji,Kanamori, Takafumi Korean Institute of Information Scientists and Eng 2013 Journal of Computing Science and Engineering Vol.7 No.2
Approximating a divergence between two probability distributions from their samples is a fundamental challenge in statistics, information theory, and machine learning. A divergence approximator can be used for various purposes, such as two-sample homogeneity testing, change-point detection, and class-balance estimation. Furthermore, an approximator of a divergence between the joint distribution and the product of marginals can be used for independence testing, which has a wide range of applications, including feature selection and extraction, clustering, object matching, independent component analysis, and causal direction estimation. In this paper, we review recent advances in divergence approximation. Our emphasis is that directly approximating the divergence without estimating probability distributions is more sensible than a naive two-step approach of first estimating probability distributions and then approximating the divergence. Furthermore, despite the overwhelming popularity of the Kullback-Leibler divergence as a divergence measure, we argue that alternatives such as the Pearson divergence, the relative Pearson divergence, and the $L^2$-distance are more useful in practice because of their computationally efficient approximability, high numerical stability, and superior robustness against outliers.