Neurocognitive and psychological profiles in pediatric arachnoid cyst

Park, Young Seok,Eom, Soyong,Shim, Kyu-Won,Kim, Dong-Seok Springer-Verlag 2009 Child's nervous system Vol.25 No.9

Exposure to lead and mercury through breastfeeding during the first month of life: A CHECK cohort study

Park, Yelim,Lee, Aram,Choi, Kyungho,Kim, Hai-Joong,Lee, Jeong Jae,Choi, Gyuyeon,Kim, Sungjoo,Kim, Su Young,Cho, Geum Joon,Suh, Eunsook,Kim, Sung Koo,Eun, So-Hee,Eom, Soyong,Kim, Seunghyo,Kim, Gun-Ha,M Elsevier 2018 Science of the Total Environment Vol.612 No.-

<P><B>Abstract</B></P> <P>Mercury and lead are naturally occurring toxicants and are responsible for various health issues including neurobehavioral and developmental disorders. Because of crucial synchronized developmental processes occurring at the early stage of life, infancy and childhood are considered as among the most susceptible windows to the exposure to these metals. Breastmilk is often the only source of nutrition during the first months of life. As breastmilk can be contaminated with these metals, breastfeeding may serve as a significant route of heavy metal exposure among infants. In order to understand current levels of exposure to mercury and lead through breastfeeding, and their associated risks, a total of 157 lactating mothers were recruited from Children's Health and Environmental Chemicals of Korea (CHECK) cohort, and breastmilk samples were collected at 15 and 30days after delivery (<I>n</I> =207). Mercury was detected from 100% of breastmilk with a median concentration of 0.59μg/L, and lead was detected in 77% of the samples with a median at 4.71μg/L. Higher concentrations of lead were found in the 30- day breastmilk than in the 15-day. Up to 45% of the breastmilk samples exceeded the normal range of the breastmilk lead suggested by WHO. Based on Monte Carlo simulation, about 71% of 15days old infants and 56% of 30days old infants were estimated at risk due to lead exposure through breastfeeding. Considering vulnerability of infants and well-known neurological toxicity of these metals, further studies to identify major exposure sources that contribute the lead concentration in breastmilk and health implication of early life stage exposure to lead among the breastfed infants are warranted.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We analyzed mercury and lead in 207 breastmilk collected at 15 and 30days after delivery. </LI> <LI> Mercury was detected from 100% of breastmilk with the median of 0. 59μg/L. </LI> <LI> Lead was detected in 77 % of breastmilk with the median of 4.71μg/L. </LI> <LI> The hazard quotient of lead exceeded 1.0 for 71% of 15days and for 56% for 30days old infants from breastfeeding. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Screening of Tuberous Sclerosis-Associated Neuropsychiatric Disorders in Korea Using the TAND Checklist

Soyoung Park,Soyong Eom,Hoon-Chul Kang,Joon Soo Lee,Heung Dong Kim,Hee Jung Chung 대한소아신경학회 2021 대한소아신경학회지 Vol.29 No.1

Purpose: The present study aimed to elucidate the clinical characteristics of children with tuberous sclerosis complex (TSC) in Korea using the Tuberous Sclerosis-Associated Neuropsychiatric Disorders (TAND) checklist to evaluate the comorbidities of neurocognitive and socioemotional problems in the Korean clinical setting. Methods: A survey based on the TAND checklist was administered to 58 children with TSC receiving treatment on an outpatient basis. Their medical records and test results were retrospectively examined. Results: At the time of TAND administration, 35 (64.8%) of the participants had focal epilepsy, three (5.6%) had generalized epilepsy, six (11.1%) had infantile spasms, and seven (13.0%) had Lennox-Gastaut syndrome. The most frequently reported behavioral problem was difficulty getting on with other people of similar age (38/58, 65.5%). Twenty patients had received previous diagnoses of psychiatric disorders, six of whom had received two or more concurrent diagnoses. A further evaluation after testing with the TAND checklist identified new psychiatric disorders in two patients. Among the 35 children who underwent a formal evaluation of intelligence, 27 (77.1%) exhibited intellectual disability. Of the school-aged patients, 65.6% (21/32) experienced difficulties with mathematics and 56.3% (18/32) with spelling. Difficulty dual-/multi-tasking (27/58, 46.6%) and low self-esteem (18, 31.0%) were the most frequent neuropsychological and psychosocial issues, respectively. Conclusion: Our findings indicate that patients with TSC tend to experience neurocognitive and socioemotional difficulties, and regular screening for TAND using the TAND checklist can be helpful for managing children with TSC in the clinical setting.

A case of laryngeal cancer induced by exposure to asbestos in a construction site supervisor

Sooyong Roh,Soyong Park,Gyeong Tae,Jaechul Song 대한직업환경의학회 2016 대한직업환경의학회지 Vol.28 No.-

Background: Construction site supervisors are exposed to many chemicals, dusts, and metals including asbestos. Asbestos is a hazardous chemical that is carcinogenic. Laryngeal cancer is not a rare disease in Korea. The most common causes of this disease are tobacco and alcohol, and representative occupational cause is asbestos. However, up to now, no case of laryngeal cancer induced by asbestos has been reported in Korea. In this study, we report such a case in a construction site supervisor. Case presentation: A 60-year-old man who had been experiencing hoarseness for 2 months was diagnosed with laryngeal cancer. The pathologic diagnosis was squamous cell carcinoma in situ, based on examination of a biopsy specimen obtained by resection of the lesion. The patient had been exposed to asbestos for 38 years at construction sites where he worked until diagnosed with laryngeal cancer. He had been exposed to asbestos when demolishing buildings and inspecting materials. Conclusion: The patient in this case worked with construction materials including asbestos and supervised construction for 38 years, and was thus exposed to asbestos at construction sites. Much of the asbestos was highly concentrated especially during demolition processes. We therefore consider the laryngeal cancer of this patient to be a work-related disease.

BLAC 모터 구동의 안전성을 위한 센서리스 제어 방식의 연구

조태호(Taeho Cho),박상준(SangJoon Park),이종철(JongCheol Lee),김준희(JunHee Kim),김연호(YonHo Kim),임동환(DongHwan Lim),박소영(SoYong Park),김현민(HyeonMin Kim) 항공우주시스템공학회 2016 항공우주시스템공학회 학술대회 발표집 Vol.2016 No.11

부모의 성격특성과 아동의 내재화, 외현화 문제

윤영 ( Young Yun ),박서현 ( Seohyun Park ),엄소용 ( Soyong Eom ) 한국영유아아동정신건강학회 2012 영유아아동정신건강연구 Vol.5 No.2

본 연구는 아동의 내재화, 외현화 문제와 부모의 성격 특성간의 관련성을 알아보고, 부모 자녀 관계에 대한 이해를 마련하는 기초자료를 제공하고자 하였다. 이를 위해 서울 소재 대학병원 소아정신과를 내원한 만 6세에서 17세에 해당하는 아동 중 심리 평가에 의뢰된 환아 60명, 이들의 어머니 60명, 아버지 60명을 대상으로 아동 청소년 행동 평가 척도(K-CBCL-Child Behavior Checklist)와 다면적 인성 검사 척도(MMPI-Minnesota Multiphasic Personality Inventory)를 사용 하여 자료를 수집, 분석하였다. 분석 결과, 첫째, 어머니의 건강염려증척도와 경조증척도는 아동의 외현화 문제와 정적인 상관을 나타냈으며, 어머니의 성격적인 특성과 아동의 내재화 문제와의 상 관은 유의미한 수준에 이르지 않았다. 둘째, 아버지의 강박증척도와 정신분열증척도는 아동의 외현 화 문제와 정적인 상관을 나타냈으며, 아버지의 반사회성척도와 편집증 척도는 아동의 내재화 문제와 정적인 상관을 나타내었다. 부모의 성격특성이 아동의 문제 행동에 영향을 미치는 정도를 알아보기 위해 회귀 분석을 한 결과, 아버지의 반사회적 척도, 편집증적 척도, 강박증적 척도, 어머니의 건강염려증 척도, 경조증 척도는 유의미한 수준에서 영향을 미치고 있는 것으로 나타내었다. 이러한 결과는 아동의 내재화 및 외현화 문제가 부모의 심리적 특성과의 양상을 보여주는 것으로, 부모의 성격특성과 아동의 문제 행동과의 관련성에 대한 좀 더 구체적인 이해에 기반을 제공하고 자 하였다. 특히 아버지의 영향력 또한 어머니의 영향력 못지않게 아동의 문제 행동과 관련성이 높다는 것을 제언하였다. This research intends to provide preliminary data to understand parent-child relationship through investigation of internalizing as well as externalizing problems of children and personality traits of parents. For this purpose, we gathered and analyzed K-CBCL (Child Behavior Checklist) and MMPI (Minnesota Multiphase Personality Inventory) for sixty children, who were requested for assessment among the children between age of six and seventeen who visited the child psychology department of a university hospital in Seoul, and their mothers and fathers(sixty each). The results are as follows. First, the Hypochondriasis index and the Hypomania index of mothers showed a positive relationship with children's externalizing problem, and no significant result was found between mothers' character traits and children’s internalizing problems. Second, the Psychasthenia and Schizophrenia indices of fathers had a positive relationship with children's externalizing problems, and the Psychopathic Deviate and Paranoid indices of fathers showed a positive relationship with children’s internalizing problems. These results imply that children’s internal and external problems have relations with the psychological nature of parents, providing a basis for more specific understanding about the relationship between parents’ character traits and children's problem behaviors. The results especially point out that fathers' influence on children is as important as mothers'.