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Jixiang Chen,Weili Jiang,Hongyan Hu,Xiaoyan Ma,Qian Li,Xianpeng Song,Xiangliang Ren,Yan Ma 한국응용곤충학회 2019 Journal of Asia-Pacific Entomology Vol.22 No.3
The joint action and sublethal effects of methoxyfenozide and lufenuron were measured against Spodoptera exigua. Methoxyfenozide and lufenuron exhibited optimum synergistic toxicity on S. exigua at a mass ratio of 4:6, and the co-toxicity coefficient (CTC) was 165.705. Third instars larvae of S. exigua were treated with methoxyfenozide (LC 15 = 21.004 ng/cm 2 ), lufenuron (LC 15 = 27.134 ng/cm 2 ), or a mixture of methoxyfenozide and lufenuron (MML, LC 15 = 16.503 ng/cm 2 ) through feeding for 72 h. Ingestion of MML by larvae significantly inhibited larval and pupal weights and pupation rate, and prolonged the larval and pupal development of S. exigua compared to individual treatment ofmethoxyfenozide or lufenuron. Both methoxyfenozide and MML treatments significantly decreased the fertility of female S. exigua. No significant changes were observed in case of adult emergence and egg hatching for different treatments. The MML-treated S. exigua exhibited significantly lower activities of polyphenol oxidase (PPO) and cytochrome P450 (CYP450) than those in S. exigua treated separately with methoxyfenozide or lufenuron. Finally, methoxyfenozide, lufenuron, and MML treatments decreased chitinase, acetylcholinesterase (AChE), carboxylesterase (CarE), and glutathione-s-transferase (GST) activities in S. exigua.
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Cyclooxygenase-2 Polymorphisms and Susceptibility to Colorectal Cancer: A Meta-Analysis
Jun Wang,Xufeng Guo,Jixiang Zhang,Jia Song,Mengyao Ji,Shijie Yu,Jing Wang,Zhuo Cao,Weiguo Dong 연세대학교의과대학 2013 Yonsei medical journal Vol.54 No.6
Purpose: Four polymorphisms, -765G>C, -1195G>A, 8473T>C, and Val511Ala, in the cyclooxygenase-2 (COX-2) gene were identified to be associated with colorectal cancer (CRC) risk. However, the results are inconsistent. The objective of this meta-analysis was to evaluate the association between these four polymorphisms and the risk of CRC. Materials and Methods: All eligible case-control studies published up to December 2012 on the association between the four polymorphisms of COX-2 and CRC risk were identified by searching PubMed and Web of Science. The CRC risk associated with the four polymorphisms of the COX-2 gene was estimated for each study by odds ratio (OR) together with its 95% confidence interval (CI), respectively. Results: A total of 15 case-control studies were included. Overall, no evidence has indicated that the -1195A allele, -765C allele, 8473C allele, and 511Ala allele are associated with susceptibility to CRC (-1195G>A: OR=1.11, 95% CI: 0.82-1.51, p=0.78; -765G>C: OR=1.08, 95% CI: 0.96-1.21, p=0.07; 8473T>C: OR=1.03, 95% CI: 0.89-1.18, p=0.91; Val511Ala:OR=0.71, 95% CI: 0.46-1.09, p=0.94). However, stratified analysis with ethnicity indicated that individuals with -765GC or GC/CC genotypes had an increased risk of CRC among Asian populations (GC vs. GG: OR=1.05, 95% CI: 0.87-1.28, p=0.03; GC+CC vs. GG: OR=1.08, 95% CI: 0.96-1.21, p=0.07). Conclusion: This meta-analysis indicated that -765G>C polymorphism was significantly associated with susceptibility to CRC in Asian populations.
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Li Yilun,Guo Shuangxi,Guo Yucheng,Yu Xiaoqi,Chen Weimin,Song Jixiang 대한조선학회 2023 International Journal of Naval Architecture and Oc Vol.15 No.-
As the exploration and exploitation of deep-sea oil and gas, along with promising polymetallic nodule&sulfides mining, have been developing toward ultra-deep waters, some innovative concepts of marine cable configuration suitable for ultra-deepwater are proposed, such as stepped cable, hybrid cable and double-stepped cable. For deep-water cables with complex configurations, the structural responses become more complicated due to their non-uniform structural properties. Because the distributed buoyancy modules along cable length might introduce more significant local bending segments. Moreover, the impacts of moving boundary, caused by the motions of top vessel and bottom mining vehicle, should be considered. Through combing the finite element simulations with the hydrodynamic models, the dynamic response analysis approach of ultra-deepwater cables is established in this study. Then the double-stepped cable responses, including axial tension, displacement along with the change of overall configurations caused by moving top vessel and bottom mining vehicle, are calculated. Moreover, wave propagation behaviors during cable response are comprehensively examined, and the influences of non-uniform structural properties on cable response and wave propagation are analyzed using the wave propagation theory of structure with axially varying properties based on the Bessel function. The results show that the presented double-stepped cable can provide suitable configurations during the dynamic response, which has good compliance performance and can effectively buffer its response caused by moving boundary excitation. Finally, we found that the response spatial-temporal evolutions present some interesting phenomena, such as the axially non-uniform characteristics lead to non-monotonic changes in response amplitude and wavelength, with local peaks occurring in the low-tension region, owing to the distributed buoyancy modules, along with axiallyvarying and discontinuous structural properties. And, there exists significant mixed effect coming from both standing waves and traveling waves.
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