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        Epidemiologic characteristics and a prognostic nomogram for patients with vulvar cancer: results from the Surveillance, Epidemiology, and End Results (SEER) program in the United States, 1975 to 2016

        Shiyuan Wei,Lu Li,Tingting Yi,Licong Su,Qi Gao,Liangzhi Wu,Zhenbo OuYang 대한부인종양학회 2023 Journal of Gynecologic Oncology Vol.34 No.6

        Objective: To elucidate clinical characteristics and build a prognostic nomogram for patients with vulvar cancer. Methods: The study population was drawn from the Surveillance, Epidemiology, and End Results (SEER) database. Patients were randomly assigned to training and validation sets. Cox proportional hazards model and competing risk model were used to identify the prognostic parameters of overall survival (OS) and cancer-specific survival (CSS) to construct a nomogram. The nomogram was assessed by concordance index (C-index), area under the curve (AUC), calibration plot, and decision curve analysis (DCA). Results: A total of 20,716 patients were included in epidemiological analysis, of whom 7,025 patients were selected in survival analysis, including 4,215 and 2,810 in training and validation sets, respectively. The multivariate Cox model showed that the predictors for OS were age, marital status, histopathology, differentiation and tumor node metastasis (TNM) stages, whether to undergo surgery and chemotherapy. However, the predictors for CSS were age, race, differentiation and TNM stages, whether to undergo surgery and radiation. The C-index for OS and CSS in the training set were 0.76 and 0.80. The AUC in the training set for 1-, 3- and 5-year OS and CSS were 0.84, 0.81, 0.80 and 0.88, 0.85, 0.83, respectively, which was similar in the validation set. The calibration curves showed good agreement between prediction and actual observations. DCA revealed that the nomogram had a better discrimination than TNM stages. Conclusions: The nomogram showed accurate prognostic prediction in OS and CSS for vulvar cancer, which could provide guidance to clinical practice.

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        Modelling and Prediction of Stress Relaxation for Thermal Bonded Nonwoven Geotextiles

        Shiyuan Sun,Xiaoping Gao,Chunhong Fu,Yudong Zhou,Xiaoying Wei,Jiaxin Li,Yiping Qiu 한국섬유공학회 2020 Fibers and polymers Vol.21 No.7

        Stress relaxation experiments were performed on three types of thermal bonded nonwoven geotextiles in this studyto model and predict their stress relaxation behaviors. Four mechanical models, including the standard linear solid mechanicsmodel, Eyring’s model, the modified two-Maxwell-unit model and the modified three-Maxwell-unit model were used topredict stress values for 600 h based on 3 and 90 h experimental relaxation data. Results indicated that Eyring’s model and themodified three-Maxwell-unit model fitted the experimental results better than the other two. Estimation using modified three-Maxwell-unit model seemed to construct an upper bound while that using Eyring’s model form a lower bound for thecorresponding experimental data. In addition, predicted curves were much closer to the experimental curve when equationsof the two models were built with the 90 h experimental data than those data of 3 h. Thus, the prediction capability of the twomodels can be substantially improved by employing the data with longer time. In summary, the combination of the modifiedthree-Maxwell-unit model and Eyring’s model can well forcast the range of actual stress during stress relaxation experimentswith the longer term experimental data.

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        Effect of Ultrasonic Power on the Microstructure and Properties of 304 Stainless Steel Welded Joints Through Cold Metal Transfer Welding Assisted with Ultrasonication

        Fei Li,Furong Chen,Peihu Gao,Wei Wang,Chenlong Yang,Shiyuan Liu 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.10

        With the development of welding technology, low heat input and high efficiency cold metal transfer welding have become the main methods of thin plate welding. However, low heat input easily forms columnar crystals, which will endanger the mechanical properties of joints. Therefore, ultrasonication treatment was applied to the cold metal transfer welding of 304 stainless steel to conduct cold metal transfer welding assisted with ultrasonication in this paper. The comparison between cold metal transfer welding assisted with ultrasonication and cold metal transfer showed that the weld grain diameter obtained by cold metal transfer welding assisted with ultrasonication was finer. In the welded joint, the maximum grain size diameter of the weld seam in cold metal transfer welding assisted with ultrasonication decreased to 375 μm, and the maximum tensile strength of cold metal transfer welding assisted with ultrasonication increased to 734 MPa. The texture intensity of the weld seam in cold metal transfer was significantly greater than that of the weld seam in cold metal transfer welding assisted with ultrasonication, which was ascribed to the improvement of the microstructure of the weld seam in cold metal transfer welding assisted with ultrasonication. In cold metal transfer welding assisted with ultrasonication, the flow performance of the welding pool increased, and the ultrasonic cavitation degree was intensified. This resulted in the significant refinement of the weld grain, the reduction of texture intensity, and an increase in the tensile strength.

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