FA1:La2+ and FA2:Sc2+ color center lasers and color image sensitization at the low coordination (0 0 1)surface of AgBr by ab initio calculations

A.S.Shalabi,I.A.Z.Al-Ansari,K.Kh.Al-Naimi,M.M.Shalaby,W.S.Abdel Halim 한국물리학회 2004 Current Applied Physics Vol.4 No.5

Supraclavicular brachial plexus block: the unsung hero of emergency department regional anesthesia

Shalaby Michael,Sahni Raghav 대한응급의학회 2023 Clinical and Experimental Emergency Medicine Vol.10 No.3

Associations between Single Nucleotide Polymorphisms of COX-2 and MMP-2 Genes and Colorectal Cancer Susceptibility in the Saudi Population

Shalaby, Manal Ali,Nounou, Howaida Attia,Alanazi, Mohammad Saud,Alharby, Othman,Azzam, Nahla,Saeed, Hesham Mahmoud Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.12

Background: It has been reported that COX-2 expression is associated with MMP-2 expression in thyroid and breast cancers, suggesting that MMPs are linked to COX-2-mediated carcinogenesis. Several polymorphisms within the MMP2 promoter region have been reported in cases with oncogenesis and tumor progression, especially in colorectal carcinogenesis. Materials and Methods: This research evaluated risk of association of the SNPs, including genes for COX-2 (AIG transition at +202) and MMP-2 (Crr transition at-1306), with colorectal cancer in 125 patients and 125 healthy controls. Results and Conclusions: Our data confirmed that MMP2 C-1306 T mutations were significantly more common in colon cancer patients than in our control Saudi population; p=O.0121. On the other hand in our study, there was no significant association between genotype distribution ofthe COX2 polymorphism and colorectal cancer; p=0.847. An elevated frequency ofthe mutated genotype in the control group as compared to the patients subjects indeed suggested that this polymorphism could decrease risk in the Saudi population. Our study confirmed that the polymorphisms that could affect the expressions of MMP-2 and COX-2 the colon cancer patients were significantly higher than that in the COX-2 negative group. The frequency of individuals with MMP2 polymorphisms in colon cancer patients was higher than individuals with combination of COX2 and MMP2 polymorphisms. Our study confirmed that individuals who carried the polymorphisms that could affect the expressions ofCOX2 are more susceptible to colon cancer. MMP2 regulatory polymorphisms could be considered as protective; further studies need to confirm the results with more samples and healthy subjects.

Applying Scrum framework in the IT service support domain

Mohamed Shalaby,Sherif El-Kassas 한국정보기술융합학회 2012 JoC Vol.3 No.1

Outcome of Colorectal Surgery in Elderly Populations

Mostafa Shalaby,Nicola Di Lorenzo,Luana Franceschilli,Federico Perrone,Giulio P. Angelucci,Silvia Quareisma,Achille L. Gaspari,Pierpaolo Sileri 대한대장항문학회 2016 Annals of Coloproctolgy Vol.32 No.4

Purpose: The aim of this study is to investigate the impact of age on short-term outcomes after colorectal surgery in terms of the 30-day postoperative morbidity and mortality rates. Methods: The subjects for the study were patients who had undergone colorectal surgery. Patients were divided into 2 groups according to age; groups A and B patients were ≥80 and <80 years old of age, respectively. Both groups were manually matched for body mass index, American Society of Anesthesiologists score, Charlson Comorbidity Index and procedure performed. Results: A total of 200 patients, 91 men (45.5%) and 109 women (54.5%), were included in this retrospective study. These patients were equally divided into 2 groups. The mean ages were 85 years in group A (range, 80 to 104 years) and 55.3 years in group B (range, 13 to 79 years). The overall 30-day postoperative mortality rate was 1% of total 200 patients; both of these 2 patients were in group A. However, this observation had no statistical significance. No intraoperative complications were encountered in either group. The overall 30-day postoperative morbidity rate was 27% (54 of 200) for both groups. The 30-day postoperative morbidity rates in groups A and B were 28% (28 of 100) and 26% (26 of 100), respectively. However, these differences between the groups had no statistical significance importance. Conclusion: Age alone should not be considered to be more of a contraindication or a worse predictor than other factors for the outcome after colorectal surgery on elderly patients.

Transanal Tube Drainage as a Conservative Treatment for Anastomotic Leakage Following a Rectal Resection

Mostafa Shalaby,Waleed Thabet,Oreste Buonomo,Nicola Di Lorenzo,Mosaad Morshed,Giuseppe Petrella,Mohamed Farid,Pierpaolo Sileri 대한대장항문학회 2018 Annals of Coloproctolgy Vol.34 No.6

Purpose: We evaluate the role of transanal tube drainage (TD) as a conservative treatment for patients with anastomotic leakage (AL). Methods: Patients treated for AL who had undergone a low or an ultralow anterior resection with colorectal or coloanal anastomosis for the treatment of rectal cancer between January 2013 and January 2017 were enrolled in this study. The data were collected prospectively and analyzed retrospectively. The primary outcomes were the diagnosis and the management of AL. Results: Two hundred thirteen consecutive patients, 122 males and 91 females, were included. The mean age was 66.91 ± 11.15 years, and the median body mass index was 24 kg/m2 (range, 20–35 kg/m2). The median tumor distance from the anal verge was 8 cm (range, 4–12 cm). Ninety-three patients (44%) received neoadjuvant therapy for nodal disease and/or locally advanced rectal cancer. Only 13 patients (6%) developed AL. Six patients developed subclinical AL as they had a defunctioning ileostomy at the time of the initial procedure. They were treated conservatively with TD under endoscopic guidance in the endoscopy unit and received intravenous antibiotics. Six weeks after discharge, these 6 patients underwent follow-up flexible sigmoidoscopy which showed a completely healed anastomotic defect with no residual stenosis. Seven patients developed a clinically significant AL and required reoperation with pelvic abscess drainage and Hartmann colostomy formation. Conclusion: These results suggest that TD for management of patients with AL is safe, cheap, and effective. Salvaging the anastomosis will help decrease the need for Hartmann colostomy formation. Proper patient selection is important.

Identification of PlexinD1 and AHDC1 as a putative interactors for Tip-1 protein

Manal Aly Shalaby,Lynne Hampson,Anthony Oliver,Ian Hampson 한국유전학회 2011 Genes & Genomics Vol.33 No.4

The class 1 PDZ domain Tip-1 protein was first identified as a binding partner for the Human T-Cell Leukaemia Virus type 1 (HTLV-1) Tax oncoprotein. It was later shown to interact with: the RhoA signaling effector Rhotekin, the Wnt signaling effector β-catenin and the E6 oncoprotein from high-risk HPV16 but not low-risk HPV6. These observations suggested that Tip-1 may be an important “hub” protein that is involved in pathways with a proven link to carcinogenesis. Based on these findings, it was decided to further characterize the cellular role of Tip-1 by carrying out a yeast two-hybrid screen to identify new binding partners in order to uncover potentially novel functions of this protein. This identified an intracellular fragment of the trans-membrane receptor plexin D1 and a C-terminal fragment of the AT hook DNA binding containing 1 (AHDC1) protein which had a carboxyl terminal PDZ binding domain consensus sequence. Both of these interactions were confirmed by yeast mating assay which was also used to show that mutant constructs of AHDC1 lacking the carboxyl PDZ binding site did not bind Tip-1. Immunofluorescent imaging of these proteins in HPV16 E6 expressing human C33A cervical carcinoma cells suggested they may co-localize.

The role of type II FB (I):Tl+ defect in laser light generation and color image formation at the low coordination surface sites of AgBr: ab initio calculations

A.S. Shalabi,A.S. Algaber,N.K. Madi,Kh.M. Eid,Z.M. Fathy 한국물리학회 2006 Current Applied Physics Vol.6 No.1

The role of type IIFB (I):Tl+ color center at low coordination surface sites of AgBr thin lms in providing tunable laser activitystructure calculations. Clusters of variable sizes were embedded in simulated Coulomb elds that closely approximate the Madelungelds of the host surfaces, and ions that are the nearest neighbors to theFB defect site were allowed to relax to equilibrium in eachcase. The calculated Stokes shifted optical transition bands suggest that laser activity is relatively weak and fades quickly as thecoordination number of the surface ions decreases from 5 (at) to 4 (edge) to 3 (corner). An attempt has been made to explain thesesurfaces were deep below the lower edges of the conduction bands of the ground-state defect-free surfaces indicating that type IIFB(I):Tl+ is suitable laser defect. The probability of orientational destruction of the two centers, attributed to the assumed saddlepoint ion congurations along theh110i axis, was found to decrease as the coordination number of the surface ions decreases. Thepossibility of exciton (energy) transfer between sites of dierent coordination numbers was claried. The GlasnerTompkins empir-ical relation was generalized to include type IIFB (I):Tl+ doped surfaces. As far as photographic sensitization is concerned, a super-sensitizer increases the sensitizing capabilities of the two examined dye molecules by increasing the relative yield of quantumeciencyU.FA sensitizes the low coordination surface sites of the defect free AgBr by lowering the bottoms of the conductionbands. The dierence in the sensitizing capabilities between the two examined dyes was estimated by calculating the quasi Fermilevels.

A Performance Comparison between XEN and KVM Hypervisors While Using Cryptographic Algorithms

Mohammed Al-Shalabi,Waleed K. Abdulraheem,Jafar Ababneh,Nader Abdel Karim International Journal of Computer ScienceNetwork S 2024 International journal of computer science and netw Vol.24 No.1

Cloud Computing is internet-based computing, where the users are provided with whatever service they need from the resources, software, and information. Recently, the security of cloud computing is considered as one of the major issues for both cloud service providers CSP and end-users. Privacy and highly confidential data make many users refuse to store their data within cloud computing, since data on cloud computing is not dully secured. The cryptographic algorithm is a technique which is used to maintain the security and privacy of the data on the cloud. In this research, we applied eight different cryptographic algorithms on Xen and KVM as hypervisors on cloud computing, to be able to measure and compare the performance of the two hypervisors. Response time and CPU utilization while encryption and decryption have been our aspects to measure the performance. In terms of response time and CPU utilization, results show that KVM is more efficient than Xen on average at 11.5% and 11% respectively. While TripleDES cryptographic algorithm shows a more efficient time response at Xen hypervisor than KVM.

F2+ defect based model for tunable laser activity and interaction of atomic halogens (F, Cl and Br) at the low coordinated surfaces of LiH: ab initio calculations

A. S. Shalabi 한국물리학회 2002 Current Applied Physics Vol.2 No.3

The twofold potential ofFþ2 sorption properties for atomic halogens is examined using ab initio calculations.Based on Stokes shifts of the examined clusters, theFþ2 laser activity was very weak, but increases signicantly as the coordination number decreases from 5 (at) to 4 (edge) to 3 (H.corner).The corner site is the least probable for relaxed excited state orientational destruction ofFþ2 .The exciton (energy) transfersurfaces of LiH.TheFþ2 color center change the nature of halogensurface interaction from physical adsorption to chemical ad-sorption.The halogensurface interactions were monotonically increasing functions of the electronegativity of the halogen and theamount of charge transferred between the halogen and the surface.The ‘‘covalent spin pairing’’ mechanism play the dominant rolein the course of adsorbatesubstrate interactions.. 2002 Elsevier Science B.V. All rights reserved.