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당뇨병환자에서 뇨증 Fibronectin농도의 증가에 관한 연구
한승범,조준승,손건영,서성문,박근용,조성래,박규영,박정모,이인규,여준기 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4
Plasma fibronectin is an α₂-glyoprotein, which is produced by vascular endothelial cells. Raised level of plasma fibronectin has been observed in diabetic patients particularly in the presence of microvascular complications. However, no available data exist about urine level of this glycoprotein in diabetic patients. We measured urine fibronectin level by ELISA methods in 54 diabetic patients who have microvascular comlications or not. The following results were obtained. 1) Urine fibronectin level(㎍/g creatinine) in diabetic group(1740.0±678.0) is increased compaired with those in normal control group(471.0±59.0). but this results were not significantly different among two groups(P>0.05). 2) Urine fibronectin level(㎍/g creatinine) was significantly increased in patients with nephropathy (6188.0±3144.0) compared with those in normal control group(471.0±59.0) and patients without nephropathy(645.0±251.0)(P<0.001). 3) There were a significant correlation between BUN, creatinine, creatinine clearance, 24hr urine total protein and urine fibronectin level in diabetic patients. Our data suggest that urine fibronectin excretion level might be used as a sensitive guide for diabectic nephropathy.
Yeo, Seung-Gu,Cho, Moon-June,Kim, Sun-Young,Lim, Seung-Pyung,Kim, Ki-Hwan,Kim, Jun-Sang 충남대학교 암연구소 2006 암연구소 업적집 Vol.5 No.-
Purpose: To evaluate the treatment outcomes of the three-dimensional conformal radiotherapy (3D-CRT), in conjunction with induction chemotherapy, for the treatment of stage III non-small cell lung cancer (NSCLC). Materials and Methods: Between November 1998 and March 2003, 22 patients with histologically proven, clinical stage III NSCLC, treated with induction chemotherapy, followed by 3D-CRT, were retrospectively analyzed. There were 21 males (96%) and 1 female (4%), with a median age of 68.5 (range, 42~79). The clinical cancer stages were IIIA and IIIB in 41 and 59%, respectively. The histologies were squamous cell carcinoma, adenocarcinoma and others in 73,18 and 9%, respectively. Twenty patients (91%) received induction chemotherapy before radiation therapy. The majority of the chemotherapy regimen consisted of cisplatin and gemcitabine. Radiation was delivered with conventional anteroposterior/ posteroanterior fields for 36 Gy, and then 3D-CRT was performed. The total radiation dose was 70.2 Gy. The median follow-up period was 17 months (range, 4~59months). Results: The median overall survival was 19 months. The two and four-year overall survival rates were 37.9 and 30.3%, respectively. The median progression-free survival was 21 months. The two and four-year progression-free survival rates were 42.1 and 21%, respectively. The prognostic factors for overall survival by a univariate analysis were age, histology and T stage (p<0.05). Acute radiation toxicities, as evaluated by the RTOG toxicity criteria, included two cases of grade 3 lung toxicity and one case of grade 2 esophagus toxicity. Conclusion: The radiation dose could be increased without a significant increment in the acute toxicities when using 3D-CRT. It also seems to be a safe, well-tolerated and effective treatment modality for stage III NSCLC. (Cancer Res Treat. 2005;37:273-278)
Simulation of the Optical Transmittance of IPS LC-Cell on Temperature Variation
Yeo, Jun-Ho,Ji, Seung-Hoon,Choi, Hyun Chul,Lee, Seung Hee,Lee, Gi-Dong TaylorFrancis 2009 Molecular Crystals and Liquid Crystals Vol.510 No.1
<P> In this paper we calculated optical transmittance of the In-Plane Switching (IPS) liquid crystal (LC) cell with respect to temperature. By considering temperature energy term in the Gibb's free energy, we could achieve the temperature parameters that need to calculate the temperature dependence on the electro-optic characteristics. The calculated temperature parameters permit us to calculate scalar order parameter S with respect to temperature, so that finally we could calculate the optical transmittance of the IPS LC cell as a function of temperature.</P>
Yeo, Seung-Gu,Cho, Moon-June,Kim, Sun-Young,Lim, Seung-Pyung,Kim, Ki-Hwan,Kim, Jun-Sang 충남대학교 암공동연구소 2006 암공동연구소 업적집 Vol.5 No.
Purpose: To evaluate the treatment outcomes of the three-dimensional conformal radiotherapy (3D-CRT), in conjunction with induction chemotherapy, for the treatment of stage III non-small cell lung cancer (NSCLC). Materials and Methods: Between November 1998 and March 2003, 22 patients with histologically proven, clinical stage III NSCLC, treated with induction chemotherapy, followed by 3D-CRT, were retrospectively analyzed. There were 21 males (96%) and 1 female (4%), with a median age of 68.5 (range, 42~79). The clinical cancer stages were IIIA and IIIB in 41 and 59%, respectively. The histologies were squamous cell carcinoma, adenocarcinoma and others in 73,18 and 9%, respectively. Twenty patients (91%) received induction chemotherapy before radiation therapy. The majority of the chemotherapy regimen consisted of cisplatin and gemcitabine. Radiation was delivered with conventional anteroposterior/ posteroanterior fields for 36 Gy, and then 3D-CRT was performed. The total radiation dose was 70.2 Gy. The median follow-up period was 17 months (range, 4~59months). Results: The median overall survival was 19 months. The two and four-year overall survival rates were 37.9 and 30.3%, respectively. The median progression-free survival was 21 months. The two and four-year progression-free survival rates were 42.1 and 21%, respectively. The prognostic factors for overall survival by a univariate analysis were age, histology and T stage (p<0.05). Acute radiation toxicities, as evaluated by the RTOG toxicity criteria, included two cases of grade 3 lung toxicity and one case of grade 2 esophagus toxicity. Conclusion: The radiation dose could be increased without a significant increment in the acute toxicities when using 3D-CRT. It also seems to be a safe, well-tolerated and effective treatment modality for stage III NSCLC. (Cancer Res Treat. 2005;37:273-278)
여승준(Seung-Jun Yeo),김창중(Chang-Joong Kim),허서원(Seo-Weon Heo),이호경(Ho-Kyoung Lee) 대한전자공학회 2007 대한전자공학회 학술대회 Vol.2007 No.11
본 논문은 MIMO 시스템에서, 두 심볼을 묶어서 전송함으로써 최대 전송률을 유지하는 준직교 시공간 블록 부호 (QOSTBC : quasi orthogonal space time block codes)의 성능을 분석하였다. QOSTBC의 전송 신호를 다차원 신호공간의 성상으로 생각하여 신호를 설계하고, 제안된 신호들의 성능을 분석하였다. 또한 다양한 신호 성화에 대하여 분석한 성능을 모의실험 결과와 비교를 통해 성능분석의 타당성을 입증하였다.
다차원 신호 공간에서 그룹 준직교 시공간 블록 부호의 신호 설계
여승준(Seung-Jun Yeo),허서원(Seo-Weon Heo),이호경(Ho-Kyoung Lee) 대한전자공학회 2008 電子工學會論文誌-TC (Telecommunications) Vol.45 No.3
본 논문은 MIMO 시스템에서, 최대 전송률을 유지하면서 최대 다이버시티를 갖는 준직교 시공간 블록 부호 (QO-STBC : quasi orthogonal space time block codes)를 다차원 신호 공간에서 설계한다. QO-STBC 부호기 중 원형심볼(based-symbols)을 두 개의 신호 쌍으로 묶어서 변형된 새로운 신호를 전송하는 방식을 grouping QO-STBC 라고 한다. 이러한 grouping QO-STBC의 최대 다이버시티 조건을 기하학적으로 살펴보고, 다차원 신호 공간에서 신호를 설계하는 방법을 제안한다. 또한 다양한 신호 성상에 대하여 설계한 부호기의 성능을 분석하고 전산 모의실험을 통하여 성능분석의 타당성을 입증한다. This paper proposes the signal design techniques of quasi-orthogonal space time block codes (QO-STBCs) on the multi-dimensional signal space. In the multiple antenna system(MIMO), QO-STBC achieves the full-diversity and full-rate by grouping two based-symbols. We study the condition for the full-diversity of the grouping QO-STBC geometrically and the performance analysis of codes on the multi-dimensional signal space regarding the various signal constellations. Simulation results show that the way of the performance analysis is validity.
풀러렌의 광중합 반응에 의해 생성된 나노 구조체의 나노 사이즈 효과
여승준(Seung Jun Yeo),박소라(Sora Park),차정옥(Jeong Ok Cha),신진호(Chin Ho Shin),안정선(Jeung Sun Ahn) 한국생산제조학회 2007 한국공작기계학회 춘계학술대회논문집 Vol.2007 No.-
상온~120K의 온도 영역에서 단일 용매(톨루엔, 벤젠, CS₂)에 녹인 fullerene(C??) 분자의 photoluminescence(PL) 스펙트럼을 측정하여 분석한 결과, C?? 분자가 용액의 액체-고체 상변이 과정에서 aggregates을 형성함을 확인하였으며, 이때 형성된 aggregates는 van der Waals 힘에 의한 약한 결합으로 이루어져 있다는 사실을 확인하였다. 또한 상온에서의 혼합 용액(벤젠-에탄올) 중의 C?? 분자의 PL 스펙트럼을 용매의 혼합비를 바꾸어 측정하여, 혼합비에 따른 PL 스펙트럼 형태의 급격한 변화가 C?? aggregates의 형성에 기인함을 알 수 있었다. 혼합용액에서 aggregates의 사이즈가 단일 용매의 액체-고체 상변이 과정에서 생성된 aggregates의 사이즈 비에 훨씬 큰 사이즈를 갖고 있음을 밝혔으며, 이러한 결과는 이들 C?? aggregates에 레이저를 조사하여 광중합반응을 일으킨 후의 고 분해능 투과형 전자 현미경(HRTEM)에 의한 관측 결과와도 일치하였다. 이들 결과는 플러렌의 광중합 반응에 의하여 형성된 새로운 나노 구조체에서의 강한 백색 발광이 내부에 형성된 3차원적인 공유결합의 네트워크로부터 기인한 나노 사이즈 효과임을 시사한다.