http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Seoyeon Chae(Seoyeon Chae),Sunhye Lee(Sunhye Lee) 한국유산균프로바이오틱스학회 2023 Current Topic in Lactic Acid Bacteria and Probioti Vol.9 No.2
Sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, poses a growing public health concern, predominantly affecting the elderly. Recent research has illuminated the pivotal role of the gut-muscle axis in sarcopenia's pathogenesis, suggesting a complex interplay between gut microbiota, metabolic pathways, and muscle health. This review offers a comprehensive examination of the emerging evidence on the gut-muscle axis, delineating its impact on muscle physiology and the onset of sarcopenia. We explore the bidirectional communication between the gut microbiota and skeletal muscles, emphasizing how alterations in gut microbiota composition and functionality can influence muscle metabolism, inflammation, and protein synthesis. Furthermore, the review highlights the mechanistic pathways, including microbial metabolites and gut-derived signals, that modulate muscle homeostasis. We also discuss the age-related changes in the gut microbiota and their corresponding effects on muscle biology. In addition, this review critically evaluates current and potential therapeutic strategies targeting the gut-muscle axis. These include dietary interventions, probiotics, prebiotics, and fecal microbiota transplantation, focusing on their efficacy in modulating the gut microbiota composition and ameliorating sarcopenia symptoms. By integrating insights from various studies, this review underscores the gut-muscle axis as a novel and promising target for therapeutic interventions in sarcopenia, paving the way for future research and clinical applications in managing its age-related conditions.
EEG and EMG recording system for sleep study with a freely moving rat
Youjin Lee,Yena Lee,Seoyoung Hwang,Hee Soo Jeong,Yunjin Kim,Yunbin Lee,Jihoo Lee,Seoyeon Park,Sang Beom Jun 한국실험동물학회 2021 한국실험동물학회 학술발표대회 논문집 Vol.2021 No.7
Sleep is known to play an important role in cognitive functions as well as in physical recovery. Especially, high-quality sleep is closely associated with smooth sleep cycles between NREM (non-rapid eye movement) and REM (rapid eye movement) sleep. It is well known that both sleep stages show clear distinction in electroencephalogram (EEG) and electromyogram (EMG) signals. Therefore, as a first step for sleep study with rodents, a sleep monitoring system must be established for stable measurement of EEG and EMG. There are two challenges for the setup. First, animals should be able to freely move without interruption of EEG or EMG recording cable, so that their natural behavior and sleep can occur. Second, long-term EEG and EMG should be recorded stably. Also, the movements of animals can cause a cable tension and moving artifacts. The movement-related artifacts can interfere with judgment of sleep stages. Also, rodent gnawing of the recording cable frequently leads to early termination of sleep study. In this study, in order to overcome these problems, acrylic cages were developed for sleep monitoring which can minimize the interruption of cables and the artifacts. Principle of lever mechanics is applied to rotational cover of the cage, and it rotates vertically in synchronization with rat’s movement. When the rat stand up, the cage cover opens up to prevent the cable from loosening. Therefore, cable tension can be stably maintained, allowing the rat to move freely without causing artifact. As a result, long-term EEG and EMG recordings are successful performed, and specific characteristics of each sleep stages can be extracted due to the high-quality recorded signals. We expected that the developed sleep monitoring setup can be applied to various long-term in vivo experiments with rats.
Seoyeon Yuk,Byoung Cheon Lee,Seulgi Kim,Woo Kyu Kang,Dongju Lee 대한금속·재료학회 2024 ELECTRONIC MATERIALS LETTERS Vol.20 No.2
Eff orts to improve the properties of composites have involved extensive studies regarding the eff ective incorporationof a polymer matrix and inorganic fi llers. In this work, we generated a stable organosilica sol with high concentrationand high purity by surface modifi cation with silane coupling agents, then integrated it with an epoxy matrix. The silicananoparticle/epoxy composite exhibited improved tensile strength because of the uniform distribution of silica in the matrix,as well as the interfacial chemical bonding between polymer and silica nanoparticles; these factors resulted in eff ective loadtransfer from matrix to fi llers. Additionally, the application of copper-clad laminates (CCLs) with prepreg-containing silicananoparticles led to substantial improvements in mechanical properties, including peel strength (0.46 kgf/cm) and storagemodulus (30.0 GPa), compared with conventional CCLs lacking silica nanoparticles. These results suggest that prepregscontaining surface-modifi ed silica nanoparticles have great potential for use as printed circuit board substrate materials inhigh-performance electronics.
Lee, Wonhee,Kim, Gi Mihn,Baik, Seoyeon,Lee, Jae W. Elsevier 2016 ELECTROCHIMICA ACTA Vol.210 No.-
<P><B>Abstract</B></P> <P>This study investigates the effect of boron/nitrogen (B/N) dual doping on the electrocatalytic activity for oxygen reduction reaction (ORR) of carbon materials that are derived from gaseous carbon dioxide (CO<SUB>2</SUB>) at 1atm. In the presence of NaBH<SUB>4</SUB>, CO<SUB>2</SUB> was converted to a B-doped carbon material which was further treated with urea at 850°C for N-doping. Through RDE and RRDE measurements, the enhanced ORR activity of the B/N dual-doped carbon was confirmed in terms of both early onset potentials and large current densities. This arose from the existence of B-N related bond and pyridinic N in the carbon network. As the amount of N content increased, the carbon material became more crystalline and the B/N dual doping led to an increase in the electron transfer number of the carbon materials, implying that the ORR occurred through a dominant four-electron transfer pathway. By utilizing the abundant greenhouse gas as a carbon source, this study provides a facile means by which to synthesize B/N dual-doped carbon for enhanced electrocatalysis.</P>