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Choi, Mi-Hyun,Kim, Hyung-Sik,Baek, Ji-Hye,Lee, Jung-Chul,Park, Sung-Jun,Jeong, Ul-Ho,Gim, Seon-Young,Kim, Sung-Phil,Lim, Dae-Woon,Chung, Soon-Cheol Williams & Wilkins Co 2015 Medicine Vol.94 No.38
ABSTRACT: In this study, a constant pressure stimulus was applied on the 3 joints (first [p1], second [p2], and third [p3] joints) of 4 fingers (index, middle, ring, and little fingers), and the activation areas within Brodmann area 2 (BA 2) were compared for these different fingers and joints by using functional magnetic resonance imaging.Eight healthy male college students (25.4 ± 1.32 years) participated in the study. Each session was composed of 3 blocks, and each block was composed of a Control phase (30 seconds) and a Pressure phase (30 seconds). No pressure stimulus was applied in the Control phase, during which the subjects would simply lay comfortably with their eyes closed. In the Pressure phase, a pressure stimulus was applied onto one of the joints of the selected finger.For each finger and joint, BA 2 areas activated by the pressure stimulus were extracted by the region of interest method. There was a significant difference in the activation areas for the different fingers (P = .042) as well as for the different joints (P = .050). The activation area decreased in the order of the little, index, and middle fingers, as well as in the order of p1, p3, and p2.
한식의 체내 대사에 미치는 영향에 대한 연구: 소변 유기산 분석을 통한 한식의 효과
신필경(Phil-Kyung Shin),천수경(Sukyung Chun),김명선(Myung Sunny Kim),박선주(Seon-Joo Park),김민정(Min Jung Kim),권대영(Dae Young Kwon),김경철(KyongChol Kim),이해정(Hae-Jeung Lee),최상운(Sang-Woon Choi) 한국영양학회 2020 Journal of Nutrition and Health Vol.53 No.3
소변은 쉽게 채취할 수 있으며 체내의 상태를 파악하기에 좋은 시료라고 할 수 있다. 본 연구에서는 2주간의 한식 섭취 후 변화된 소변 유기산 지표를 찾을 수 있었다. 그 결과 에너지 대사와 관련 있는 대사산물인 succinate, hydroxymethylglutarates 뿐만 아니라 tryptophan 대사물로써 신경전달 물질대사 지표인 5-hydroxyindoleacetate, 비타민 B6, 염증, 면역과도 관련이 있는 kynurenate, 장내세균과 관련 있는 indican이 한식의 섭취를 통해 유의한 차이로 변화하는 것을 확인하여 한식의 효능이 어떤 대사를 통하여 이루어 지는지의 방향 제시를 하였다. 또한 소변 유기산이 한식의 대사에 미치는 영향을 측정하는 생체지표로서의 활용 가능성도 보여주었다. 객관적인 지표로서 확증하기 위해 더욱 큰 표본에서의 연구, 성별, 질병별 다양화한 연구를 통해 관찰된 지표들의 재현성을 확인하여 생체 지표로서의 유효성 검증이 필요하겠다. Purpose: To determine the metabolic influence of the traditional Korean diet (K-diet), which has been regarded as a healthy diet, we investigated the profile of urine organic acids that are intermediates of various types of metabolism including energy metabolism. Methods: Ten women aged 50–60 years were recruited and randomly divided into 2 diet groups, K-diet and control diet, the latter of which is a Westernized Korean diet that is commonly consumed by Koreans nowadays. Before and after the 2-week intervention, 46 urine organic acids were determined using LC/MS/MS, along with clinical parameters. Results: The average concentrations of succinate (4.14 ± 0.84 μg/mg creatinine vs. 1.49 ± 0.11, p = 0.0346) and hydroxymethylglutarate (3.67 ± 0.36 μg/mg creatinine vs. 2.97 ± 0.29, p = 0.0466), both of which are intermediates of energy metabolism, decreased in the K-diet group after the 2-week intervention, but these were not observed in the control diet group. In particular, the average concentration of succinate in the K-diet group was lower than that in the control group (3.33 ± 0.56 μg/mg creatinine vs. 1.49 ± 0.11, p = 0.0284) after 2 weeks. The concentrations of two tryptophan metabolites, 5-hydroxyindolacetate (3.72 ± 0.22 μg/mg creatinine vs. 3.14 ± 0.21, p = 0.0183) and indican (76.99 ± 8.35 μg/mg creatinine vs. 37.89 ± 10.06, p = 0.0205) also decreased only in the K-diet group. After the 2-week intervention, the concentration of kynurenate, another tryptophan metabolite, was lower in the K-diet group than that in the control diet group (3.96 ± 0.51 μg/mg creatinine vs. 2.90 ± 0.22, p = 0.0356). Interestingly, the urine level of kynurenate was positively correlated with BMI (r = 0.61424, p = 0.0003) and total cholesterol (r = 0.46979, p = 0.0088), which decreased only in the K-diet group (239.40 ± 15.14 mg/dL vs. 198.20 ± 13.25, p = 0.0163). Conclusion: The K-diet alters the urinary excretion of organic acids involved in energy metabolism and tryptophan metabolism, suggesting the influence of the K-diet on these types of metabolism. Urine organic acids changed by the K-diet may serve as biomarkers in future studies.
농업인에 적용 가능한 스마트 개인보호장비 개발 동향 분석
채혜선(Hye Seon Chae),고명선(Myung Sun Ko),김효철(Hyo Cher Kim),김경수(Kyung Su Kim),최동필(Dong Phil Choi),김경란(Kyung Ran Kim),이경숙(Kyung Suk Lee) 대한인간공학회 2017 大韓人間工學會誌 Vol.36 No.6
Objective: The purpose of this study is to clarify the implications of development of smart personal protective equipment which can enhance occupational safety for farmers through development trend and development case analysis of smart personal protective equipment (SPPE) applicable to agriculture sector. Background: Most of the farmers work alone in the open far away from home, so their geographical accessibility is low, which may lead to serious disasters due to delayed response in case of an accident. Therefore, it is expected that the life - friendly service that can cope with accidents in rural areas and the spread of work safety equipment using ICT and IOT will improve the welfare of farmers scientifically and efficiently. Method: Patents were searched by year of application from 1990 to 2016 using the New WIPS ON patent information database. Among collected 268 data, 150 valid patents for quantitative trend analysis. Using Google, the prototypes or commercialized products for smart personal protection devices were searched. And a selection of 16 cases of products applicable to the agricultural safety sector was chosen and discussed. Results: The patent applications of smart personal protection equipment, which combines ICT and IoT technologies, have progressed most recently and have been declining since 2012. Only about 31% of the 150 selected valid patents tended to match the body"s wear and protection areas. The smart personal protection equipment uses various biometric information from the combination of devices to allow the wearer to voluntarily recognize danger or escape from danger. Conclusion: The research and development of the Rural Smart Personalization Equipment for Preventing Farming and Disaster Prevention should be established in the Rural Community and the cooperative management system for the safety inspection and crisis responses in the rural communities. Application: The commercialization of smart personal protective equipment and the application of agriculture sector are difficult to solve, but it is expected that it will be a breakthrough in raising industrial disaster response ability in agriculture in the blind spot.
Joon-Pyo Jeun,Phil-Hyun Kang,Byung-Seon Choi,Chang Hyun Roh 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.2
Chelate resin is a resin that has an exchange group which can form chelates with various metal ions. It shows higher selectivity for metal ions than ion exchange resin and can selectively remove characteristic metal ions. In an aqueous solution containing metal ions, chelate resin can adsorb specific metal ions, and the separated chelate resin can desorb the adsorbed metal ions by changing temperature or pH, so chelate resin has the advantage of being reusable. Chelate resin has been used industrially as an adsorbent to adsorb and separate heavy metal ions in wastewater, and is also used for the purpose of recovering precious or rare metals contained in industrial wastewater or industrial waste. Against this background, there is a need to develop chelate resins with higher adsorption capacity. Acrylic fiber is defined as a man-made fiber made from a linear synthetic polymer with fiberforming ability consisting of more than 85% acrylonitrile. It is a man-made fiber that is often used as a substitute for wool because it has good thermal insulation properties like wool and is warm and soft to the touch. It is a fiber rich in cyano groups due to its high content of acrylonitrile, and has the advantage of being able to be used as a variety of functional fibers through modification of cyano groups. In this study, the amination reaction of acrylic fiber was performed using diethylenetriamine, and the adsorption characteristics for metal ions were evaluated according to the reaction conversion rate. In order to improve the amination efficiency, 400 kGy was irradiated using a 2.5 MeV electron beam accelerator, and through this, the crosslinking rate of acrylic fiber was able to be improved up to 80%. Water and ethanol were used as cosolvents for the amination reaction in a ratio of 60/40 vol/vol, respectively, and a reaction yield of 178% was obtained after 120 minutes of reaction. Using the chelate resin prepared in this way, the adsorption performance for metal ions was evaluated through Atomic Absorption Spectrometry analysis.