PRACTICAL ACTIVE POWER FILTERS USING SI-THYRISTORS

S.ATOH,T.SHIOTA,T.YAMADA,S.ARAKI,M.KOHATA 전력전자학회 1989 ICPE(ISPE)논문집 Vol.- No.-

We have developed a practical active power filters using SI(Static Induction)-Thyristors, a self-turn-off device excellent in high speed switching characteristics. This active filter was applied to VVVF inverter-driven water distribution system and has operated in the best conditions since the end of the last year. The active filter we have devel­oped uses the compensating algorithm based on the instantaneous spatial vector theory and achieves nig11 speed and high accuracy controls by perform­ing the on-line arithmetic operation with a digital signal processor. As for compensating perform­ances suppression effects within 2% have been a-chieved as compared with the fundamental compo­nents at the 5th to 19th harmonics components of inverter current contained in the input current of inverter system.<br/>

Effect of Surface Treatment on Bonding Strength of Zirconia Ceramics to Resin Cements

Sato H,Yamasaki Y 대한치과재료학회 2011 대한치과기재학회 학술대회 Vol.2011 No.5

Early Flowering and Increased Expression of a FLOWERING LOCUS T-like Gene in Chrysanthemum Transformed with a Mutated Ethylene Receptor Gene mDG-ERS1(etr1-4)

Shigeru Satoh,Yuino Murakoshi,Ai Hojo,Keiko Chisaka,Taro Harada,Shigeru Satoh 한국식물학회 2012 Journal of Plant Biology Vol.55 No.5

Ethylene has an inhibitory effect on flowering in a short-day (SD) plant chrysanthemum (Chrysanthemum morifolium Ramat.). In this study, we used a hexaploid chrysanthemum ‘Sei-Marine’and found that its transgenic lines transformed with a mutated ethylene receptor gene mDGERS1(etr1-4), which conferred reduced ethylene sensitivity (J. Plant Biol. 51: 424-427, 2008), opened flowers earlier than the non-transformed control. We examined whether the accelerated flower induction in the transformant occurred through the enhanced expression of chrysanthemum genes homologous to FLOWERING LOCUS T (FT), a floral inducer gene in Arabidopsis. We cloned three cDNAs for FT homologs (CmFTL1, CmFTL2, and CmFTL3) from ‘Sei-Marine’. CmFTL2 putatively encodes a non-functional gene product due to a frame shift caused by a 2 bp-deletion in the coding region. RT-PCR analysis revealed differential expression patterns of CmFTL genes in the transgenic and control lines,suggesting that these genes might be under the control of ethylene. CmFTL1/2 mRNA level was lower in a SD condition than a long-day (LD) condition. CmFTL3 mRNA accumulated abundantly under SD condition as compared with LD condition in the transgenic line. These results suggest the association of increased expression of CmFTL3gene with the accelerated flowering in the transgenic line with reduced ethylene sensitivity.

RECENT ADVANCES IN HEPATOTOXICITY STUDIES

Satoh, Tetsuo Korean Society of ToxicologyKorea Environmental Mu 1991 Toxicological Research Vol.7 No.2

Hepatotoxicity has many facets. Those to be discussed in this review include the mechanism for the hepatotoxic effects, nature of the injury, and animal models of hepatotoxicity suitable for the detection of chemical injury. Some therapeutic drugs used for treatment of hepatitis are also presented. In addition, as an important and serious problem in future, alternative toxicity testing is discussed.

Two Ethylene Signaling Pathways in Senescing Carnation Petals: Exogenous Ethylene-induced Expression of Genes for 1-Aminocyclopropane-1-Carboxylate (ACC) Synthase and ACC Oxidase is Different from That of the Gene for Cysteine Proteinase

Satoh, Shigeru,Kosugi, Yusuke,Iwazaki, Yujiro,Shibuya, Kenichi,Waki, Keisuke The Korean Society of Plant Biotechnology 2000 Plant molecular biology and biotechnology research Vol.2 No.2

Carnation petals exhibit autocatalytic ethylene production and wilting during senescence. The autocatalytic ethylene production is induced by the expression of 1-aminocyclopropane-1-carboxylate (ACC) synthase and ACC oxidase genes, whereas the wilting of petals is related to expression of the cysteine proteinase (CP) gene. Until recently, it has been believed that these two phenomena, autocatalytic ethylene production and wilting, are regulated in concert in senescing carnation petals, since the two phenomena occurred closely in parallel. Our studies with petals of a transgenic carnation harboring a sense ACC oxidase transgene and petals of carnation flowers treated with 1,1-dimethyl-4-(phenylsulfonyl) semicarbazide showed that the expression of ACC synthase and ACC oxidase genes and that of CP are regulated differently in carnation psanetals. Interestingly, in the petals of transgenic carnation, the transcript for CP was accumulated but the transcripts for ACC synthase and ACC oxidase were not accumulated in response to exogenous ethylene. Based on these results, we hypothesized that two ethylene signaling pathways, one leading to the expression of ACC synthase and ACC oxidase genes and the other leading to the expression of CP gene, are functioning in senescing carnation petals.

The damage resistance of triple liner system against the local pressure on the uneven ground surface in the sea area landfill site

Satoh, Takeshi,Akai, Tomoyuki,Kamon, Masashi Korean Geotechnical Society 2006 지반 : 한국지반공학회지 Vol.22 No.12

Randomized phase II trial of nimotuzumab plus irinotecan versus irinotecan alone as second-line therapy for patients with advanced gastric cancer

Satoh, Taroh,Lee, Kyung Hee,Rha, Sun Young,Sasaki, Yasutsuna,Park, Se Hoon,Komatsu, Yoshito,Yasui, Hirofumi,Kim, Tae-You,Yamaguchi, Kensei,Fuse, Nozomu,Yamada, Yasuhide,Ura, Takashi,Kim, Si-Young,Muna Springer Japan 2015 Gastric cancer Vol.18 No.4

<P><B>Background</B></P><P>This multicenter, randomized phase II trial was conducted to compare the efficacy and safety of nimotuzumab plus irinotecan (N-IRI) versus irinotecan alone (IRI) in patients with advanced gastric cancer (AGC) showing disease progression after previous 5-fluorouracil-based therapy.</P><P><B>Methods</B></P><P>Irinotecan-naive patients (<I>n</I> = 82) received N-IRI (nimotuzumab 400 mg weekly plus irinotecan 150 mg/m<SUP>2</SUP> biweekly) or IRI (irinotecan 150 mg/m<SUP>2</SUP> biweekly) until disease progression. The primary endpoint was progression-free survival (PFS), and the secondary endpoints were overall survival (OS), response rate (RR), safety, tolerability, and the correlation between efficacy and tumor epidermal growth factor receptor (EGFR) expression.</P><P><B>Results</B></P><P>Of 83 patients, 40 and 43 patients were randomly assigned to the N-IRI and IRI groups, respectively. In the N-IRI/IRI treatment group, median PFS was 73.0/85.0 days (<I>P</I> = 0.5668), and median OS and RR at 18 months were 250.5/232.0 days (<I>P</I> = 0.9778) and 18.4/10.3 %, respectively. Median PFS and OS in the EGFR 2+/3+ subgroups were 118.5/59.0 and 358.5/229.5 days, respectively. The RR was 33.3/0.0 % in the N-IRI/IRI treatment group. The incidence of grade 3 or higher adverse events was 77.5/64.3 %. No adverse events of grade 3 or higher skin rash or grade 3 or higher infusion-related reaction were reported.</P><P><B>Conclusions</B></P><P>There was no superiority of N-IRI over IRI alone in terms of PFS in 5-fluorouracil-refractory AGC patients. However, N-IRI showed potential improvement in the EGFR 2+/3+ subgroup based on improved RR, PFS, and OS.</P>

Gender-Related Differences in a Process of the Age-Dependent Alterations of the Elements in Monkey Sino-Atrial Node

Satoh, Hiroyasu,Tohno, Setsuko,Minami, Takeshi,Oishi, Takao,Hayashi, Motoharu,Tohno, Yoshiyuki The Korean Society of Pharmacology 2010 The Korean Journal of Physiology & Pharmacology Vol.14 No.5

Gender differences in the trace elements of monkey sino-atrial (SA) node were investigated in a process of age-dependent alterations. Sixty hearts from Japanese and rhesus monkeys (30 male and 30 female) used were aged ranging from 1-day- to 30-year-old. The elements were analyzed using an inductively coupled plasma-atomic emission spectrometer (ICP-AES). Advancing age decreased all the trace elements. Ca, P, S and Mg significantly decreased. The correlation coefficients of Ca and P were $-0.178{\pm}0.081$ (p<0.05) and $-0.088{\pm}0.022$ (p<0.05) in male (n=30), and $-0.095{\pm}0.026$ (p<0.05) and $-0.069{\pm}0.017$ (p<0.05) in female (n=30), respectively. The age-dependent coefficients for Fe/Ca, Zn/Ca, Fe/P, Fe/S, Zn/S, Fe/Mg and Zn/Mg were exhibited markedly in male, but all was less in female. In gender-related differences, only a ratio of P/Ca (p<0.05) was significantly observed with ageing. The trace elements such as Cu, Se and Sn were less detected in the SA nodes. These results indicate that the age-dependent changes in the ratios of elements are appeared more rapidly in male monkey SA node, and the gender difference is observed in ratio of P/Ca. The different attenuations may be involved with the age- and gender-related SA nodal functions.

Whole learning algorithm of the neural network for modeling nonlinear and dynamic behavior of RC members

Satoh, Kayo,Yoshikawa, Nobuhiro,Nakano, Yoshiaki,Yang, Won-Jik Techno-Press 2001 Structural Engineering and Mechanics, An Int'l Jou Vol.12 No.5

A new sort of learning algorithm named whole learning algorithm is proposed to simulate the nonlinear and dynamic behavior of RC members for the estimation of structural integrity. A mathematical technique to solve the multi-objective optimization problem is applied for the learning of the feedforward neural network, which is formulated so as to minimize the Euclidean norm of the error vector defined as the difference between the outputs and the target values for all the learning data sets. The change of the outputs is approximated in the first-order with respect to the amount of weight modification of the network. The governing equation for weight modification to make the error vector null is constituted with the consideration of the approximated outputs for all the learning data sets. The solution is neatly determined by means of the Moore-Penrose generalized inverse after summarization of the governing equation into the linear simultaneous equations with a rectangular matrix of coefficients. The learning efficiency of the proposed algorithm from the viewpoint of computational cost is verified in three types of problems to learn the truth table for exclusive or, the stress-strain relationship described by the Ramberg-Osgood model and the nonlinear and dynamic behavior of RC members observed under an earthquake.

Overview of Anti - Rheumatoid Drugs

Satoh, Tetsuo 서울시립대학교 산업기술연구소 2001 산업기술연구소논문집 Vol.9 No.2