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      • KCI등재

        Investigation of key parameters influence on performance of direct ethanol fuel cell (DEFC)

        Saeed Heysiattalab,Mehdi Safari,Mohsen Shakeri,M.M. Keikha 한국공업화학회 2011 Journal of Industrial and Engineering Chemistry Vol.17 No.4

        Direct ethanol fuel cell has been declared as a new alternative for other fuel cells such as direct methanol fuel cell and proton exchange membrane fuel cells. In this paper, effects of key parameters such as temperature, anode and cathode flow rate, molarity and cathode pressure have been investigated on ethanol fuel cell performance. Maximum power density and fuel cell performance will increase by temperature rising because of ion conductivity, diffusion and reaction rate increase. Molarity augmentation will increase ethanol concentration in catalyst layer and reaction rate which leads to better performance of the cell. Anode and cathode flow rate and cathode pressure will slightly increase fuel cell performance.

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        The Effects of Air Pollution on Ischemic Stroke Admission Rate

        Hossein Alimohammadi,Sara Fakhri,Hojjat Derakhshanfar,Seyed-Mostafa Hosseini-Zijoud,Saeed Safari,Hamid Reza Hatamabadi 전남대학교 의과학연구소 2016 전남의대학술지 Vol.52 No.1

        The present study aimed to determine the relationship between the level of air pollutantsand the rate of ischemic stroke (IS) admissions to hospitals. In this retrospectivecross-sectional study, stroke admissions (January-March 2012 and 2013) to an emergencydepartment and air pollution and meteorological data were gathered. The relationshipbetween air pollutant levels and hospital admission rates were evaluated usingthe generalize additive model. In all 379 patients with IS were referred to the hospital(52.5% male; mean age 68.2±13.3 years). Both transient (p<0.001) and long-term(p<0.001) rises in CO level increases the risk of IS. Increased weekly (p<0.001) andmonthly (p<0.001) average O3 levels amplifies this risk, while a transient increase inNO2 (p<0.001) and SO2 (p<0.001) levels has the same effect. Long-term changes inPM10 (p<0.001) and PM2.5 (p<0.001) also increase the risk of IS. The findings showedthat the level of air pollutants directly correlates with the number of stroke admissionsto the emergency department.

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        Muscimol as a treatment for nerve injury-related neuropathic pain: a systematic review and meta-analysis of preclinical studies

        Hamzah Adel Ramawad,Parsa Paridari,Sajjad Jabermoradi,Pantea Gharin,Amirmohammad Toloui,Saeed Safari,Mahmoud Yousefifard 대한통증학회 2023 The Korean Journal of Pain Vol.36 No.4

        Background: Muscimol’s quick onset and GABAergic properties make it a promising candidate for the treatment of pain. This systematic review and meta-analysis of preclinical studies aimed at summarizing the evidence regarding the efficacy of muscimol administration in the amelioration of nerve injury-related neuropathic pain. Methods: Two independent researchers performed the screening process in Medline, Embase, Scopus and Web of Science extracting data were extracted into a checklist designed according to the PRISMA guideline. A standardized mean difference (SMD [95% confidence interval]) was calculated for each. To assess the heterogeneity between studies, I2 and chi-square tests were utilized. In the case of heterogeneity, meta-regression and subgroup analyses were performed to identify the potential source. Results: Twenty-two articles met the inclusion criteria. Pooled data analysis showed that the administration of muscimol during the peak effect causes a significant reduction in mechanical allodynia (SMD = 1.78 [1.45–2.11]; P < 0.0001; I2 = 72.70%), mechanical hyperalgesia (SMD = 1.62 [1.28–1.96]; P < 0.0001; I2 = 40.66%), and thermal hyperalgesia (SMD = 2.59 [1.79–3.39]; P < 0.0001; I2 = 80.33%). This significant amendment of pain was observed at a declining rate from 15 minutes to at least 180 minutes post-treatment in mechanical allodynia and mechanical hyperalgesia, and up to 30 minutes in thermal hyperalgesia (P < 0 .0001). Conclusions: Muscimol is effective in the amelioration of mechanical allodynia, mechanical hyperalgesia, and thermal hyperalgesia, exerting its analgesic effects 15 minutes after administration for up to at least 3 hours.

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        Frequency of posttrauma complications during hospital admission and their association with Injury Severity Score

        Dasdar Shayan,Yousefifard Mahmoud,Ranjbar Mehri Farhang,Forouzanfar Mehdi,Mazloom Hamid,Safari Saeed 대한응급의학회 2023 Clinical and Experimental Emergency Medicine Vol.10 No.4

        Objective Multiple trauma is associated with a remarkable risk of in-hospital complications, which harm healthcare services and patients. This study aimed to assess the incidence of posttrauma complications, their relationship with poor outcomes, and the effect of the Injury Severity Score (ISS) on their occurrence.Methods This retrospective cohort study was conducted at a pair of trauma centers, between January 2020 and December 2022. All hospitalized adult patients with multiple trauma were included in this study. Multivariable logistic regression was used to identify factors related to posttrauma complications.Results Among 727 multiple trauma patients, 90 (12.4%) developed in-hospital complications. The most frequent complications were pneumonia (4.8%), atelectasis (3.7%), and superficial surgical site infection (2.5%). According to multivariable logistic regression, ISS, the length of stay in the intensive care unit (ICU), the length of stay in the hospital, and mortality were significantly associated with complications. The complication rate increased by 17% with every single-unit increase in ISS (adjusted odds ratio [OR], 1.17; 95% confidence interval [CI], 1.00–1.38). Per every 1-day increase in the ICU or hospital stay, the complication rate increased by 65% (adjusted OR, 1.65; 95% CI, 1.00–2.73) and 20% (adjusted OR, 1.20; 95% CI, 1.03–1.41), respectively. Posttrauma complications were also significantly more common in patients with mortality (adjusted OR, 163.30; 95% CI, 3.04–8,779.32). In multiple trauma patients with a higher ISS, the frequency, severity, and number of complications were significantly increased.Conclusion In-hospital complications in multiple trauma patients are frequent and associated with poor outcomes and mortality. ISS is an important factor associated with posttrauma complications.

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