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Directing Government Procurement as an Incentive of Production
( Xiang Qun Chen ) 세종대학교 경제통합연구소 1995 Journal of Economic Integration Vol.10 No.1
Due to the inefficacy of current government procurement policy (Baldwin [1970, 1984], Baldwin and Richardson [1971], and Miyagiwa [1991]), a new policy scheme that embodies the incentive of production is proposed in this paper. The policy, which ties positively the government purchase from each of the domestic firms to its sales to consumers, is found to have the effects of increasing domestic output and reducing imports. Moreover, the optimal policy is such that it induces the domestic firms to produce at the socially optimal level.
Development of Urban and Rural Institutions for the Aged
Xiang Qun Jiang,Nina Liu 한국노인복지학회 2013 International Journal of Welfare for the Aged Vol.29 No.-
In this paper, we aim at discussing the development of urban and rural institutions for the aged on the base of presenting the conditions of them. We maintain that the direction of the development of institutions for the aged is to keep the quantity while expanding, at the same time the government had better pay more attention to the reform of rural institutions for the aged. In addition, in the city, A problem?the imbalance of public, private urban institutions for the aged in supply and demand, need to be settled as soon as possible.
Review and Analysis of China's Population Aging and the Situations of the Elderly
Jiang Xiang Qun,Yang Qing Fang,Zheng Yan Hui 한국노인복지학회 2012 International Journal of Welfare for the Aged Vol.26 No.-
The population age structure has changed obviously in the past 60 years since foundation of P.R China. China`s population aging growth trend emerged in 1970s. In recent years, population aging accelerates and has an important effect on the socio-economic development. China`s population aging in the early time is dominated by the fertility decline, and the influence of mortality decline continues to grow in the later stage. It is limited to solve the problem of population aging by improving the fertility level, because it is a real problem that the number of the elderly is large and it`s a huge increment. The issue of the elderly family`s support decline, and the inadequate economic and social security should be resolved by society development and distribution system, etc.
ZNF424, a novel human KRAB/C2H2 zinc finger protein, suppresses NFAT and p21 pathway
( Yue Qun Wang ),( Jun Mei Zhou ),( Xiang Li Ye ),( Yong Qi Wan ),( Yong Qing Li ),( Xiao Yan Mo ),( Wu Zhou Yuan ),( Yan Yan ),( Na Luo ),( Ze Qun Wang ),( Xiong Wei Fan ),( Yun Deng ),( Xiu Shan Wu 생화학분자생물학회 2010 BMB Reports Vol.43 No.3
Zinc finger-containing transcription factors are the largest single family of transcriptional regulators in mammals, which play an essential role in cell differentiation, cell proliferation, apoptosis, and neoplastic transformation. Here we have cloned a novel KRAB-related zinc finger gene, ZNF424, encoding a protein of 555aa. ZNF424 gene consisted of 4 exons and 3 introns, and mapped to chromosome 19p13.3. ZNF424 gene was ubiquitously expressed in human embryo tissues by Northern blot analysis. ZNF424 is conserved across species in evolution. Using a GFP-labeled ZNF424 protein, we demonstrate that ZNF424 localizes mostly in the nucleus. Transcriptional activity assays shows ZNF424 suppresses transcriptional activity of L8G5-luciferase. Overexpression of ZNF424 in HEK- 293 cells inhibited the transcriptional activity of NFAT and p21, which may be silenced by siRNA. The results suggest that ZNF424 protein may act as a transcriptional repressor that suppresses NFAT and p21 pathway to mediate cellular functions. [BMB reports 2010; 43(3): 212-218]
China's Population Aging and the Status of the Elderlyin the Past Decade
Jiang Xiang Qun,Yang Qing Fang 한국노인복지학회 2011 International Journal of Welfare for the Aged Vol.25 No.-
The population age structure has changed obviously in the past 60 years since foundation of P.R China. China`s population aging growth trend emerged in 1970s. In recent years, population aging accelerates and has an important effect on the socio-economic development. China`s population aging in the early time is dominated by the fertility decline, and the influence of mortality decline continues to grow in the later stage. It is limited to solve the problem of population aging by improving the fertility level, because it is a real problem that the number of the elderly is large and it`s a huge increment. The issue of the elderly family`s support decline, and the inadequate economic and social security should be resolved by society development and distribution system, etc.
An Introductory Study of China`s Population Aging and the Current Elderly Status
( Jiang Xiang Qun ) 한남대학교 사회과학연구소 2014 사회과학연구 Vol.23 No.-
In this century, the population age structure has changed obviously in the past 60 years since foundation of P.R China. China``s population aging growth trend emerged in 1970s. In recent years, population aging accelerates and has an important effect on the socio-economic development. It is limited to solve the problem of population aging by improving the fertility level, because it is a real problem that the number of the elderly is large and it``s a huge increment. The issue of the elderly family``s support decline, and the inadequate economic and social security should be resolved by society development and distribution system, etc. China``s population aging in the early time is dominated by the fertility decline, and the influence of mortality decline continues to grow in the later stage. Overall, we project rapid population growth in the China``s eldelry.
CK2 phosphorylates AP-2α and increases its transcriptional activity
( Kai Qun Ren ),( Shuang Lin Xiang ),( Fang Li He ),( Wen Feng Zhang ),( Xiao Feng Ding ),( Yan Yang Wu ),( Li Ping Yang ),( Jian Lin Zhou ),( Xiang Gao ),( Jian Zhang ) 생화학분자생물학회 2011 BMB Reports Vol.44 No.7
Transcription factor AP-2α involves in the process of mammalian embryonic development and tumorigenesis. Many studies have shown that AP-2α functions in association with other interacting proteins. In a two-hybrid screening, the regulatory subunit β of protein casein kinase 2 (CK2β) was identified as an interacting protein of AP-2α; we confirmed this interaction using in-vitro GST pull-down and in-vivo co-immunoprecipitation assays; in an endogenous co-immunoprecipitation experiment, we further found the catalytic subunit α of protein casein kinase 2 (CK2α) also exists in the complex. Phosphorylation analysis revealed that AP-2α was phosphorylated by CK2 kinase majorly at the site of Ser429, and such phosphorylation could be blocked by CK2 specific inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) in a dose-dependent manner. Luciferase assays demonstrated that both CK2α and CK2β enhanced the transcription activity of AP-2α; moreover, CK2β increased the stability of AP-2α. Our data suggest a novel cellular function of CK-2 as a transcriptional co-activator of AP-2α.