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천핑위안 민족문학사학회 2000 민족문학사연구 Vol.16 No.-
The essay, dealing with heroic novels of Jin-Yong(金庸), is extracted from professor Chen's latest work, the Form and the Structure of the History of Literature(1999.3, Guangsi Education Publishing). The author of the essay, Chen Ping-Yuan received M. A in literature at Zhongshan University and Ph. D at Beijing University and presently he is the professor of the Chinese literature department and the academic adviser of the doctor's course in Beijing University. His academic concern has wide range, such as 20th century's Chinese literature, modem Chinese history of science, Chines novel and Chinese prose, and it came out in his writings, like Narrative Form of Chinese Novel and Chines Novel of 20th Century. Hitherto, Chinese heroic novel was always under-valued in the field of literature but the enormous popularity of one writer, Jin-Yong, was so powerful that his heroic novel became the matter of scientific concern not mention in Chinese academic world but in the international academic world. The essay, with reflection, criticizes his success from the viewpoint of modern Chinese literature so its subject is the interior case of the Chinese literature. For all, some issues, like the problem of vulgarity in literature, the excessive inclination toward pure literature and the inheritance of the literary tradition, which arise from argument on Chinese heroic novel, are crucial points of the history of Korean new literature. Therefore, our reviewing this essay can be a lesson for studying the history of modern Korean literature.
Israeli Acute Paralysis Virus: Epidemiology, Pathogenesis and Implications for Honey Bee Health
Chen, Yan Ping,Pettis, Jeffery S.,Corona, Miguel,Chen, Wei Ping,Li, Cong Jun,Spivak, Marla,Visscher, P. Kirk,DeGrandi-Hoffman, Gloria,Boncristiani, Humberto,Zhao, Yan,vanEngelsdorp, Dennis,Delaplane, Public Library of Science 2014 PLoS pathogens Vol.10 No.7
<▼1><P><I>Israeli acute paralysis virus</I> (IAPV) is a widespread RNA virus of honey bees that has been linked with colony losses. Here we describe the transmission, prevalence, and genetic traits of this virus, along with host transcriptional responses to infections. Further, we present RNAi-based strategies for limiting an important mechanism used by IAPV to subvert host defenses. Our study shows that IAPV is established as a persistent infection in honey bee populations, likely enabled by both horizontal and vertical transmission pathways. The phenotypic differences in pathology among different strains of IAPV found globally may be due to high levels of standing genetic variation. Microarray profiles of host responses to IAPV infection revealed that mitochondrial function is the most significantly affected biological process, suggesting that viral infection causes significant disturbance in energy-related host processes. The expression of genes involved in immune pathways in adult bees indicates that IAPV infection triggers active immune responses. The evidence that silencing an IAPV-encoded putative suppressor of RNAi reduces IAPV replication suggests a functional assignment for a particular genomic region of IAPV and closely related viruses from the Family <I>Dicistroviridae</I>, and indicates a novel therapeutic strategy for limiting multiple honey bee viruses simultaneously and reducing colony losses due to viral diseases. We believe that the knowledge and insights gained from this study will provide a new platform for continuing studies of the IAPV–host interactions and have positive implications for disease management that will lead to mitigation of escalating honey bee colony losses worldwide.</P></▼1><▼2><P><B>Author Summary</B></P><P>The mysterious outbreak of honey bee Colony Collapse Disorder (CCD) in the US in 2006–2007 has attracted massive media attention and created great concerns over the effects of various risk factors on bee health. Understanding the factors that are linked to the honey bee colony declines may provide insights for managing similar incidents in the future. We conducted this study to elucidate traits of a key honey bee virus, Israeli acute paralysis virus. We then developed an innovative strategy to control virus levels. The knowledge and insights gained from this study will have positive implications for bee disease management, helping to mitigate worldwide colony losses.</P></▼2>
Yong-Ping Chen,Feng-Bin Lu,Da-Zhi Chen,Lu Chen,En-De Hu,Jin-Lu Wu,Hui Li,Yue-Wen Gong,Zhuo Lin,Xiao-Dong Wang,Ji Li,Xiao-Ya Jin,Lan-Man Xu 한국분자세포생물학회 2019 Molecules and cells Vol.42 No.12
MicroRNA-223-3p (miR-223-3p) is one of the potential microRNAs that have been shown to alleviate inflammatory responses in pre-clinical investigations and is highly encased in exosomes derived from bone mesenchymal stem cells (MSC-exosomes). MSC-exosomes are able to function as carriers to deliver microRNAs into cells. Autoimmune hepatitis is one of the challenging liver diseases with no effective treatment other than steroid hormones. Here, we examined whether MSC-exosomes can transfer miR-223-3p to treat autoimmune hepatitis in an experimental model. We found that MSC-exosomes were successfully incorporated with miR-223-3p and delivered miR-223-3p into macrophages. Moreover, there was no toxic effect of exosomes on the macrophages. Furthermore, treatments of either exosomes or exosomes with miR-223-3p successfully attenuated inflammatory responses in the liver of autoimmune hepatitis and inflammatory cytokine release in both the liver and macrophages. The mechanism may be related to the regulation of miR-223-3p level and STAT3 expression in the liver and macrophages. These results suggest that MSC-exosomes can be used to deliver miR-223-3p for the treatment of autoimmune hepatitis.
Monoview/dual-view switchable liquid crystal display.
Chen, Chao Ping,Lee, Joong Ha,Yoon, Tae-Hoon,Kim, Jae Chang Optical Society of America 2009 Optics letters Vol.34 No.14
<P>We present an optical device capable of displaying in two distinct viewing modes, i.e., monoview and dual-view modes. The monoview mode has a joint viewing cone and allows only the same image or video content to be displayed. The dual-view mode splits one viewing cone into two so that two different pieces of information can be displayed simultaneously in the left and the right viewing directions from the screen. Each viewing mode can be mutually switched through the modulation of the birefringence of liquid crystals. This proposed device has technical advantages of easy operation, low cost, and versatility of applications.</P>
Development of a Small Tea Plucking Machine
( Ping-lang Yen ),( Nai-wen Chang ),( Chen-ya Chen ),( Hong-xuan Wei ),( Shih-fangchen ),( Wei-yang Hwang ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1
Tea plucking in Taiwan suffers of serious labor shortage due to agricultural population decreasing and aging. The problems become even worse in hot season of tea plucking and cause tremendous economic loses for farmers. Current solutions of introducing tea harvesting machinery to substitute human power were not adequately suitable to Taiwan's geographical specialty. These machines were found difficult to operate efficiently in mountain areas, or in small tea farms, and farms with narrow ridge to ridge. This paper has proposed a tea plucking prototype that is specially designed to operate in mountain areas and for small scale tea farm. The machine contains a carrier, a tea cutter and a motorized mechanism. The carrier of small size was able to be moved by human and its tea plucking module is motorized. At the same time the height of cutter was automatically adjusted by the controller so that tea leaves can be evenly trimmed during the carrier movement. The prototype successfully demonstrated the efficiency of tea plucking can be increased and workload for human could be significantly reduced. In conclusion, the developed small electrical tea plucking machine was proved feasible for the release of labor shortage problem in Taiwan’s tea plucking industry.
Double-layer Fabry-P$\acute{e}$rot filter interferometric modulator display
Chen, Chao Ping,Xiong, Yuan,Yang, Yuxing,Li, Xiao,Li, Hongjing,He, Gufeng,Lu, Jiangang,Su, Yikai 한국정보디스플레이학회 2013 Journal of information display Vol.14 No.4
Presented is an interferometric modulator display characterized by double layers of liquid crystal (LC) Fabry-P$\acute{e}$rot filters. With this design, no polarizers and color filters are needed, and both the color and amplitude can be tuned by electrically controlling the LC's birefringence. Instead of the conventional RGB trisubpixel color scheme, a bisubpixel structure is proposed to render a super-wide color gamut. Through simulations, the device performance was numerically studied. The device was proven to be quite suitable for green-display application.
Chen, Jin-Lian,Sun, Shi-Zhong,Miao, Cui-Ping,Wu, Kai,Chen, You-Wei,Xu, Li-Hua,Guan, Hui-Lin,Zhao, Li-Xing The Korean Society of Ginseng 2016 Journal of Ginseng Research Vol.40 No.4
Background: Biocontrol agents are regarded as promising and environmental friendly approaches as agrochemicals for phytodiseases that cause serious environmental and health problems. Trichoderma species have been widely used in suppression of soil-borne pathogens. In this study, an endophytic fungus, Trichoderma gamsii YIM PH30019, from healthy Panax notoginseng root was investigated for its biocontrol potential. Methods: In vitro detached healthy roots, and pot and field experiments were used to investigate the pathogenicity and biocontrol efficacy of T. gamsii YIM PH30019 to the host plant. The antagonistic mechanisms against test phytopathogens were analyzed using dual culture, scanning electron microscopy, and volatile organic compounds (VOCs). Tolerance to chemical fertilizers was also tested in a series of concentrations. Results: The results indicated that T. gamsii YIM PH30019 was nonpathogenic to the host, presented appreciable biocontrol efficacy, and could tolerate chemical fertilizer concentrations of up to 20%. T. gamsii YIM PH30019 displayed antagonistic activities against the pathogenic fungi of P. notoginseng via production of VOCs. On the basis of gas chromatography-mass spectrometry, VOCs were identified as dimethyl disulfide, dibenzofuran, methanethiol, ketones, etc., which are effective ingredients for antagonistic activity. T. gamsii YIM PH30019 was able to improve the seedlings' emergence and protect P. notoginseng plants from soil-borne disease in the continuous cropping field tests. Conclusion: The results suggest that the endophytic fungus T. gamsii YIM PH30019 may have a good potential as a biological control agent against notoginseng phytodiseases and can provide a clue to further illuminate the interactions between Trichoderma and phytopathogens.