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      • Development of the ASHRAE Global Thermal Comfort Database II

        ,ldvá,ry Lič,ina, Veronika,Cheung, Toby,Zhang, Hui,de Dear, Richard,Parkinson, Thomas,Arens, Edward,Chun, Chungyoon,Schiavon, Stefano,Luo, Maohui,Brager, Gail,Li, Peixian,Kaam, Soazig Elsevier 2018 Building and environment Vol.142 No.-

        <P><B>Abstract</B></P> <P>Recognizing the value of open-source research databases in advancing the art and science of HVAC, in 2014 the ASHRAE Global Thermal Comfort Database II project was launched under the leadership of University of California at Berkeley's Center for the Built Environment and The University of Sydney's Indoor Environmental Quality (IEQ) Laboratory. The exercise began with a systematic collection and harmonization of raw data from the last two decades of thermal comfort field studies around the world. The ASHRAE Global Thermal Comfort Database II (Comfort Database), now an online, open-source database, includes approximately 81,846 complete sets of objective indoor climatic observations with accompanying “<I>right-here-right-now</I>” subjective evaluations by the building occupants who were exposed to them. The database is intended to support diverse inquiries about thermal comfort in field settings. A simple web-based interface to the database enables filtering on multiple criteria, including building typology, occupancy type, subjects' demographic variables, subjective thermal comfort states, indoor thermal environmental criteria, calculated comfort indices, environmental control criteria and outdoor meteorological information. Furthermore, a web-based interactive thermal comfort visualization tool has been developed that allows end-users to quickly and interactively explore the data.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The scope, development, contents, and accessibility of the Comfort Database is documented. </LI> <LI> The Comfort Database II includes approximately 76,000 complete sets of thermal comfort data. </LI> <LI> The Comfort Database provides access to the collected raw data. </LI> <LI> Web-based interactive visualization tool was developed that allows end-users to interactively explore the data. </LI> </UL> </P>

      • KCI등재

        Tunneling Enhanced Structure for Improving the Performance of Ultraviolet Light-emitting Diodes

        Jinxing Wu,Peixian Li,Xiaowei Zhou 대한전자공학회 2020 Journal of semiconductor technology and science Vol.20 No.6

        The novel AlGaN-based ultraviolet light-emitting diode (UV-LED) with a tunneling enhancement structure is proposed. The tunneling enhanced structure consists of an ITO layer, an extremely thin AlN layer, and a p+-GaN layer. Under forward bias, compared to traditional devices, tunneling enhanced UV-LEDs can shorten the width of the tunneling region. In addition, the dielectric constant of the AlN layer in the tunnel area is small, which can effectively increase the transport of holes from the ITO layer to the MQWs active region. Due to the increased hole concentration and drift speed, for a 300 ㎛ × 254 ㎛ UV-LED chip, the optical output power increased by 19.6% at 120 ㎃. Therefore, the proposed tunneling enhanced structure provides a simple and effective way to increase the light output power of UV-LEDs.

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        Clinical Evidence of Chemotherapy or Endocrine Therapy Maintenance in Patients with Metastatic Breast Cancer: Meta-analysis from Randomized Clinical Trials and Propensity Score Matching of Multicentre Cohort Study

        Wei Ren,Yunfang Yu,Huangming Hong,Ying Wang,Quanlong Gao,Yongjian Chen,Peixian Chen,Jianli Zhao,Qiyun Ou,Dagui Lin,Tuping Fu,Yujie Tan,Chenchen Li,Xinxin Xie,Guolin Ye,Jun Tang,Herui Yao 대한암학회 2022 Cancer Research and Treatment Vol.54 No.4

        Purpose This study aims to comprehensively evaluate the clinical efficacy of chemotherapy or endocrine therapy maintenance in metastatic breast cancer (MBC) patients. Materials and Methods The meta-analysis of randomized clinical trials (RCTs) and propensity score matching of multicenter cohort study evaluated MBC patients who underwent first-line chemotherapy or endocrine therapy maintenance. This study is registered with PROSPERO: CRD42017071858 and ClinicalTrials.gov: NCT04258163. Results A total of 2,867 patients from 15 RCTs and 760 patients from multicenter cohort were included. The results from meta-analysis showed that chemotherapy maintenance improved progression-free survival (PFS) (hazard ratio [HR], 0.63; 95% confidence interval [CI], 0.54 to 0.73; p < 0.001; moderate-quality evidence) and overall survival (OS) (HR, 0.87; 95% CI, 0.78 to 0.97; p=0.016; high-quality evidence) than observation. In the cohort study, for hormone receptor–positive MBC patients, chemotherapy maintenance improved PFS (HR, 0.67; 95% CI, 0.52 to 0.85; p < 0.001) and OS (HR, 0.55; 95% CI, 0.42 to 0.73; p < 0.001) compared with observation, and endocrine therapy maintenance also improved PFS (HR, 0.65; 95% CI, 0.53 to 0.80; p < 0.001) and OS (HR, 0.55; 95% CI, 0.44 to 0.69; p < 0.001). There were no differences between chemotherapy and endocrine therapy maintenance in PFS and OS (all p > 0.05). Regardless of the continuum or switch maintenance therapy, showed prolonged survival in MBC patients who were response to first-line treatment. Conclusion This study provided evidences for survival benefits of chemotherapy and endocrine therapy maintenance in MBC patients, and there was no difference efficacy between chemotherapy and endocrine therapy maintenance for hormone receptor–positive patients.

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