http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Titania nanopores with dual micro-/nano-topography for selective cellular bioactivity
Gulati, Karan,Moon, Ho-Jin,Li, Tao,Sudheesh Kumar, P.T.,Ivanovski, Saš,o Elsevier 2018 Materials Science and Engineering C Vol.91 No.-
<P><B>Abstract</B></P> <P>This letter describes a simple surface modification strategy based on a single-step electrochemical anodization towards generating dual micro- and nano-rough horizontally-aligned TiO<SUB>2</SUB> nanopores on the surface of clinically utilized micro-grooved titanium implants. Primary macrophages, osteoblasts and fibroblasts were cultured on the nano-engineered implants, and it was demonstrated that the modified surfaces selectively reduced the proliferation of macrophages (immunomodulation), while augmenting the activity of osteoblasts (osseo-integration) and fibroblasts (soft-tissue integration). Additionally, the mechanically robust nanopores also stimulated osteoblast and fibroblast adhesion, attachment and alignment along the direction of the pores/grooves, while macrophages remained oval-shaped and sparsely distributed. This study for the first time reports the use of cost-effectively prepared nano-engineered titanium surface via anodization, with aligned multi-scale micro/nano features for selective cellular bioactivity, without the use of any therapeutics.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Single-step fabrication of dual micro-rough and nanoporous titanium surfaces </LI> <LI> Mechanically robust aligned nanopores with preserved underlying micro-features </LI> <LI> Upregulated attachment and adhesion of osteoblasts and fibroblasts </LI> <LI> Reduced macrophage proliferation and adherence </LI> <LI> Osteoblasts and fibroblasts align parallel to the nanopore arrangement. </LI> </UL> </P>
Sudheesh Kumar C. P.,Sujatha C.,Shankar Krishnapillai 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.10
Dynamic responses of simply supported non-uniform beams traversed by a moving oscillator are analysed in this paper. An approximate analytical method based on Rayleigh-Ritz (R-R) formulation is developed. The fundamental approximate mode obtained from R-R method is used in the present formulation to determine the responses of the beam and the oscillator. Effects of surface irregularities on the displacement and acceleration responses of the beam and the vehicle are also analysed. The results are compared with those obtained using Finite element method (FEM). A numerical example is provided to illustrate the validity of the present method which shows that the proposed method is simple, computationally more efficient compared to FEM and gives fairly good results. Though the single-mode approach used in the present paper is a classical one and numerous studies on the responses of uniform beams under moving loads have been reported in the past, its application to non-uniform beams (for which there does not exist any closed form expression for mode shapes) under a moving load, especially a moving oscillator, is presented for the first time.
Goodness of fit test for uniform distribution with censored observation
Sreedevi E. P.,Kattumannil Sudheesh K. 한국통계학회 2023 Journal of the Korean Statistical Society Vol.52 No.2
We develop new goodness of fit test for uniform distribution based on a conditional moment characterization. We study the asymptotic properties of the proposed test statistic. We also present a goodness of fit test for uniform distribution to incorpo-rate the right censored observations and studied its properties. A Monte Carlo simu-lation study is carried out to evaluate the finite sample performance of the proposed tests. We illustrate the test procedures using real data sets.
K.N. Sharafudeen,A. Adithya,S. Vijayakumar,P. Sudheesh,B. Kalluraya,K. Chandrasekharan 한국물리학회 2011 Current Applied Physics Vol.11 No.4
The nonlinear optical characteristics of some organic materials namely coumarin derivatives [3-[(2E)-3-phenylprop-2-enoyl]-2H-chromen-2-one(Cm1) and 3-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-enoyl}-2H-chromen-2-one (Cm2)] doped in a polymer matrix of polymethylmethacrylate (PMMA) have been studied. The Z-scan study on these composite films reveals that the compounds exhibit a self-focusing effect at 532 nm. The nonlinear absorption coefficient, nonlinear refractive index and second-order molecular hyperpolarizability are measured. The optical power limiting experiment is carried out and it is attributed to reverse saturable absorption due to excited state absorption in the samples. This article also reports the enhancement of third-order nonlinearity by substituting with an electron donor group and hence establishes the electronic nature of nonlinearity.