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RISS 인기검색어
- 검색키워드
- 저자 : Sudheesh Kumar, P.T. (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
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Sudheesh Kumar C. P.,Sujatha C.,Shankar Krishnapillai 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.10
Dynamic responses of simply supported non-uniform beams traversed by a moving oscillator are analysed in this paper. An approximate analytical method based on Rayleigh-Ritz (R-R) formulation is developed. The fundamental approximate mode obtained from R-R method is used in the present formulation to determine the responses of the beam and the oscillator. Effects of surface irregularities on the displacement and acceleration responses of the beam and the vehicle are also analysed. The results are compared with those obtained using Finite element method (FEM). A numerical example is provided to illustrate the validity of the present method which shows that the proposed method is simple, computationally more efficient compared to FEM and gives fairly good results. Though the single-mode approach used in the present paper is a classical one and numerous studies on the responses of uniform beams under moving loads have been reported in the past, its application to non-uniform beams (for which there does not exist any closed form expression for mode shapes) under a moving load, especially a moving oscillator, is presented for the first time.
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Sudheesh Kannan,Nethra S Surhonne,Chethan Kumar R,Kavitha B,Devika Rani D,Raghavendra Rao R S 대한마취통증의학회 2018 Korean Journal of Anesthesiology Vol.71 No.2
Background: Bilateral superficial cervical plexus block (BSCPB) provides good postoperative analgesia, but its effect on anesthetic consumption is unknown. This study evaluated the effects of BSCPB on sevoflurane consumption during thyroid surgery. Methods: Fifty patients were randomly allocated into groups A and B of 25 each in this prospective double-blind study. Group A received BSCPB with 20 ml 0.25% bupivacaine, whereas group B received 20 ml saline immediately before entropy-guided general anesthesia. Intraoperative hemodynamic parameters, end-tidal sevoflurane concentration, minimum alveolar concentration, and sevoflurane consumption were recorded. Postoperative pain was assessed using a visual analog scale, and the time of the first request for analgesia was noted. All side effects were recorded. Results: Demographics were comparable. Mean sevoflurane consumption [for 30 min: group A = 7.2 (1.1) ml, group B = 8.8 (2.0) ml, P = 0.001; for 60 min: group A = 13.5 (1.7) ml, group B = 16.5 (3.9) ml, P = 0.002] and mean end-tidal sevoflurane concentration [for 30 min: group A = 1.2% (0.2%), group B = 1.4% (0.2%), P = 0.008; for 60 min: group A = 1.2% (0.1%), group B = 1.4% (0.2%), P = 0.010] were significantly lower in group A. Patients in group A had a longer duration of analgesia [361.6 (79.5) min vs. 151.0 (60.2) min, P < 0.001] compared to those in group B. Conclusions: Preinduction BSCPB during thyroid surgery significantly reduced sevoflurane consumption and increased the duration of postoperative analgesia.
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Titania nanopores with dual micro-/nano-topography for selective cellular bioactivity
Gulati, Karan,Moon, Ho-Jin,Li, Tao,Sudheesh Kumar, P.T.,Ivanovski, Saš,o Elsevier 2018 Materials Science and Engineering C Vol.91 No.-
<P><B>Abstract</B></P> <P>This letter describes a simple surface modification strategy based on a single-step electrochemical anodization towards generating dual micro- and nano-rough horizontally-aligned TiO<SUB>2</SUB> nanopores on the surface of clinically utilized micro-grooved titanium implants. Primary macrophages, osteoblasts and fibroblasts were cultured on the nano-engineered implants, and it was demonstrated that the modified surfaces selectively reduced the proliferation of macrophages (immunomodulation), while augmenting the activity of osteoblasts (osseo-integration) and fibroblasts (soft-tissue integration). Additionally, the mechanically robust nanopores also stimulated osteoblast and fibroblast adhesion, attachment and alignment along the direction of the pores/grooves, while macrophages remained oval-shaped and sparsely distributed. This study for the first time reports the use of cost-effectively prepared nano-engineered titanium surface via anodization, with aligned multi-scale micro/nano features for selective cellular bioactivity, without the use of any therapeutics.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Single-step fabrication of dual micro-rough and nanoporous titanium surfaces </LI> <LI> Mechanically robust aligned nanopores with preserved underlying micro-features </LI> <LI> Upregulated attachment and adhesion of osteoblasts and fibroblasts </LI> <LI> Reduced macrophage proliferation and adherence </LI> <LI> Osteoblasts and fibroblasts align parallel to the nanopore arrangement. </LI> </UL> </P>
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