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- 저자 : Osman Kose (검색결과 5 건)
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Acute Generalized exanthematous pustulosis Due to oral Use of Blue Dyes
( Osman Sener ),( Osman Kose ),( Ozgur Kartal ),( Mukerrem Safali ) 대한내과학회 2011 The Korean Journal of Internal Medicine Vol.26 No.3
Acute generalized exanthematous pustulosis is a rare severe pustular cutaneous adverse reaction characterized by a rapid clinical course with typical histological findings. It is accompanied by fever and acute eruption of non-follicular pustules overlying erythrodermic skin. The causative agents are most frequently antibacterial drugs. We present a patient with acute generalized exanthematous pustulosis caused by methylene blue and indigotin dyes.
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Health Tourism with Data Mining: Present State and Future Potentials
Gamze Kose,Osman Eralp Colakoglu 한국디지털융합학회 2023 IJICTDC Vol.8 No.1
Health Tourism is a trendy interest area as it allows individuals to travel another country for receiving health services while experiencing touristic opportunities. There are many benefits of health tourism in terms of costs, services, and experiences. By combining both health and tourism area, it welcomes many research directions in not only healthcare and tourism but also marketing and business management. Among these the area of Health Tourism is intensively connected with digital solutions since it is important to reach out individuals in different countries and enabling them to decide and come to the host country for receiving services. So, the data is very important for establishing innovative Health Tourism applications. However, one question arising is about how to analyze, process and use the data effectively within the purposes of such applications. This paper tries to answer this question from the perspective of Data Mining. As the Data Mining allows creating descriptive and predictive new knowledge from the known data, its use in digital Health Tourism applications has a remarkable value. In this context, this paper firstly ensures the connection between Health Tourism and Data Mining, and then discusses about present state as well as the future. It is believed that the outcomes from this paper will be a triggering factor for further research in Data Mining, which is currently a niche application way in Health Tourism.
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Tasargol Omer,Darbaz Isfendiyar,Ergene Osman,Zabitler Feride,Deniz Aziz,Kose Selin Guven,Kose Halil Cihan,Tulgar Serkan 대한마취통증의학회 2023 Korean Journal of Anesthesiology Vol.76 No.2
Background: Animal and other experimental studies have demonstrated increased block time and quality when α- and β-cyclodextrin drugs are combined with local anesthetics. However, to our knowledge, no study has utilized γ-cyclodextrins in such a combination. In the present study, we used an animal model to evaluate the effects of different doses of the combined administration of γ-cyclodextrin (sugammadex) and bupivacaine on the duration of sciatic nerve blocks in rats. Methods: Sciatic nerve blocks were performed with a 0.20 ml mixture in all groups. For the non-experimental groups, this mixture consisted of 0.2 ml saline (Sham group), 0.2 ml sugammadex (Group S), or 0.16 ml bupivacaine 0.5% and 0.04 ml saline (Group B). For the experimental groups, 0.16 ml bupivacaine 0.5% was administered along with 0.01 ml sugammadex and 0.03 ml saline (Group BS1), 0.02 ml sugammadex and 0.02 ml saline (Group BS2), or 0.04 ml sugammadex (Group BS4). Proprioception, nociception, and motor function were evaluated until the sciatic block was completely reversed.Results: Motor, proprioceptive, and nociceptive blockades occurred within 5 min in all experimental groups. In Group BS4, the duration of the motor, proprioceptive, and nociceptive blockades was significantly increased compared with the other experimental groups. However, in Groups BS1 and BS2, only the duration of the nociceptive blockade was significantly increased.Conclusions: The combined administration of sugammadex and bupivacaine for sciatic nerve blocks in rats led to a significant increase in the duration of motor, proprioceptive, and nociceptive blockades.
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Early and Late Complications after Inguinofemoral Lymphadenectomy for Vulvar Cancer
Cirik, Derya Akdag,Karalok, Alper,Ureyen, Isin,Tasci, Tolga,Kalyoncu, Rukiye,Turkmen, Osman,Kose, M Faruk,Tulunay, Gokhan,Turan, Taner Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.13
Background: We aimed to determine the frequency of early and late complications following groin surgery for vulvar cancer and analyze possible risk factors. Materials and Methods: This retrospective cohort study included 99 women who underwent for vulvar cancer. The early (${\leq}1$ month) complications were wound infection, breakdown and lymphocyst and late (>1 month) complications were lower limb lymphedema, incontinence and erysipelas. The risk factors for developing each of the complications were analyzed with regression analysis. Results: In the entire cohort, 29 (29.3%) women experienced early and 12 (12.1%) had late complications. Wound complications including infection and breakdown were the leading early complications (23.2%). In the multivariate analysis, both obesity (body mass index ${\geq}30kg/m^2$) and advanced age (${\geq}65years$) were found as independent predictive factors for early complications. Obese women of advanced age had 6.32 times more risk of experiencing any of the early complications, when compared to non-obese and young women (55.6% vs 8.7%). The most common late complication was lower limb lymphedema (10.1%) that was more frequently seen in young women. However, neither age nor lymph node count were significantly associated with the occurrence of lower limb lymphedema. Conclusions: More than 40% of the women suffered from postoperative complications after inguinofemoral lymphadenectomy in the current study. While advanced age and obesity were the significant predictors for any of the early complications, there was no identified risk factor for lower limb lymphedema.
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Sacit Nuri Gorgel,Yigit Akin,Esra Meltem Koc,Osman Kose,Serkan Ozcan,Yuksel Yilmaz 대한비뇨의학회 2019 Investigative and Clinical Urology Vol.60 No.3
Purpose: Imaging studies can show metastasis in testicular cancer (TCa); however, a test for risk of metastasis in TCa has not been described. The ratio of aspartate aminotransferase to alanine aminotransferase, also called the De Ritis ratio (DRR), is used for many other malignancies. We aimed to evaluate the association between preoperatively assessed DRR and prognosis in patients with TCa. Materials and Methods: One hundred twenty-eight patients with TCa were enrolled in a retrospective study between March 2007 and January 2017. Clinical, biochemical, and pathological data were recorded. Univariate and multivariate logistic regression analyses were used. The prognostic value of DRR and the threshold value were assessed by use of receiver operating characteristic curves. Significance was defined as p<0.05. Results: Mean follow-up was 37±9.7 months. There were 45 and 73 TCa patients with and without lymph node metastasis, respectively. Lung metastases and other solid organ metastases occurred in 14 and 4 patients, respectively. The optimal DRR threshold was 1.30 for both retroperitoneal lymph node involvement and metastasis. DRR was determined as an independent prognostic factor for retroperitoneal lymph node involvement and organ metastasis in univariate and multivariate analyses (p<0.001, p=0.006 and p=0.002, p=0.047, respectively). Conclusions: A preoperative DRR greater than 1.30 may be an independent risk factor for retroperitoneal lymph node involvement and organ metastases in patients with TCa.
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