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Dong Woo Chang,Bong Kyung Kim,Jae Hoon Shin,Young Min Yoon,Seung Hyun Oh,Yeo Sung Yoon,Sung-Hyeok Hong,Ki Chang Lee,Young Won Lee,Kang Moon Seo,Oh-Kyeong Kweon,Jung Hee Yoon,Nam-Shik Shin,Kyu Ho Lee,J 대한해부학회 2010 Anatomy & Cell Biology Vol.43 No.2
In order to study the treatment of aneurysms, the technique of making experimental aneurysms in laboratory animals must be established. In our study, to examine the feasibility of making experimental aneurysm and selective angiography on the common carotid artery in rabbits and to determine the size of experimental aneurysm after surgery, saccular aneurysms were fashioned on the right common carotid artery in 17 rabbits using a vein pouch technique. Selective angiography of the common carotid artery was performed immediately after surgery, and at 1 week, 4 weeks, and 8 weeks after surgery. Also, histological changes in the aneurysms were observed. In 16 rabbits with established successful experimental aneurysm, no differences were found in diet intake and behavior before and after surgery. The patency of the carotid artery was confirmed by selective angiography. The average size of the aneurysm immediately after surgery was similar to that of 1 week postoperatively in selective angiography, however it increased with time at 4weeks and 8 weeks. Histologically, infiltration of inflammatory cells and hemorrhage were found at the junction of the carotid artery and the vein pouch at 1 week, which disappeared at 4 weeks and 8 weeks. This study suggests experimental saccular aneurysm using the vein pouch technique might form aneurysms similar to that of the human in its properties such as increment of size, and selective angiography might be suitable for assessment of experimental aneurysm. Therefore, this animal model may be suitable for investigating new treatment methodologies for human aneurysms.
$Preventic^{\circledR}$를 섭취한 개에 발생한 위확장증 1례
양현국,홍성혁,박재헌,서강문,권오경,남치주,Yang Hyun-Gouk,Hong Sung-Hyeok,Park Jae-Heoun,Seo Kang-Moon,Kweon Oh-Kyeong,Nam Tchi-Chou 한국임상수의학회 1993 한국임상수의학회지 Vol.10 No.1
A German shepherd dog, male, seven-month-old, with gastric dilatation was examined clinicopathologically and radiographically. X-ray findings showed radiopaque linear materials, which were identified a number of pieces of commercial antiparasitic collar, $Preventic^{\circledR}$(Amitraz, Virbac) by gastrotomy. The dog became good a day after removal of the materials in the stomach. It was considered that the gastric dilatation was caused by rapid absorption of the amitraz which could induce paralysis of stomach.