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( Moon Kyung Shin ),( Yoo Sun Kim ),( Jung Hyun Kim ),( Sung Hoon Kim ),( Yuri Kim ) 한국임상영양학회 2015 Clinical Nutrition Research Vol.4 No.4
The aim of this study was to examine dietary pattern, nutritional intake, and diet quality of Korean pregnant women with ges-tational diabetes mellitus (GDM). Between October 2008 and May 2012, 166 pregnant women diagnosed with GDM completed a questionnaire and dietary intake was assessed using a 3-day food record. Blood pressure, fasting plasma glucose, and gly-cated hemoglobin (HbA1c) concentrations were measured and oral glucose tolerance test (OGTT) was performed. Two major dietary patterns (“carbohydrate and vegetable” and “western” patterns) were identified through factor analysis. Dietary pattern scores for each dietary pattern were categorized into tertiles. The dietary quality index-international (DQI-I) was used to mea-sure overall diet quality. Subjects with higher carbohydrate and vegetable pattern scores reported less physical activity (p < 0.05) and have higher diastolic blood pressure levels (p = 0.05). After adjusting for age and energy intake, higher carbohydrate and vegetable pattern scores were associated with higher sodium intakes (p = 0.02), but lower intakes of fat (p = 0.002) and other micronutrients. On the other hand, higher western pattern scores were associated with higher fat intake (p = 0.0001), but lower intakes of sodium (p = 0.01) and other micronutrients. Higher scores for both dietary patterns were associated with lower scores in the moderation category of the DQI-I (p < 0.0001). HbA1c and fasting plasma glucose levels were significantly lower among participants with high DQI-I than those with low DQI-I (p < 0.05). The study findings suggest that many Korean women with GDM do not consume nutritionally adequate or balanced diets, regardless of dietary pattern.
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( Sung Min Park ),( Jeong Min Kim ),( Gun Wook Kim ),( Margaret Song ),( Hoon Soo Kim ),( Hyun Chang Ko ),( Moon Bum Kim ),( Byung Soo Kim ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2
Background: Pruritus is common in psoriasis, but the pathogenesis of pruritus in psoriasis remains unclear. Moreover, reliable information on the characteristics of pruritus according to psoriasis clinical phenotypes is lacking. Objectives: To investigate the clinical characteristics of pruritus according to clinical phenotypes of psoriasis and to determine its association with inflammatory mediators related to pruritus.Methods: Clinical data on pruritus were collected by questionnaire including Leuvin itch scale. Quantitative measurement of serum neuropeptides and cytokines including substance P (SP), histamine, vasoactive intestinal peptide (VIP), neuropeptide Y (NPY), calcitonin gene related peptide (CGRP) and interleukin-31 (IL-31) were analyzed. Results: Eighty-four patients with psoriasis (56 men, 28 women; mean age, 48.1 years) were divided into two groups according to clinical phenotype: chronic stable and eruptive inflammatory. There was no significant difference of pruritus intensity, psoriasis area severity index, and serum level of SP, histamine, VIP, NPY, CGRP, IL-31 between two groups. Serum SP level was significantly higher in patients with pruritus compared with patients without pruritus and normal controls. Conclusion: Substance P may play a role in pruritus of psoriasis as a systemic factor. However, characteristics of pruritus, serum neuropeptides related to pruritus did not differ according to clinical phenotype of psoriasis.
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( Sung Woo Moon ),( Sang Hoon Lee ),( Ho Il Yoon ),( Moo Suk Park ),( Young Sam Kim ),( Joon Jang ),( Jae Ho Lee ),( Choon Taek Lee ),( Jin Haeng Jung ),( Hyo Sup Shim ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-
Background: In non-small cell lung cancer (NSCLC) patients, concomitant idiopathic pulmonary fibrosis (IPF) or emphysema is related to poor survival independently. Combined pulmonary fibrosis and emphysema (CPFE) is a condition with features of both pulmonary fibrosis and emphysema. Here, we evaluated the effect of CPFE and IPF alone on the outcomes of NSCLC patients. Patients and Methods: We retrospectively evaluated 283 patients with CPFE or IPF who were diagnosed with NSCLC between November 2003 and February 2018 at two tertiary care hospitals in South Korea. Patients were classified into the CPFE and IPF groups according to chest computed tomography findings. Results: One-hundred-and-seven patients (37.8%; mean age: 70.1 years; men 97.2%) had CPFE. Compared with IPF patients, CPFE patients had higher smoking history; lower DLco (78.0% vs 64.8%, p< 0.001), lower forced expiratory volume in 1 second. Of all patients with NSCLC, 71.7% died during the follow-up period; 71.6% died in the CPFE group and 72.0% in the IPF group. Multivariate logistic regression analysis showed that CPFE (odds ratio [OR]: 2.26, 95% confidence interval [CI]: 1.09-4.69; P = 0.029) was significantly correlated with acute exacerbations (AEs). In a Cox proportional hazards analysis, stage >III NSCLC, higher Eastern Cooperative Oncology Group performance status, and higher gender-age-physiology index score was related to higher mortality. However, CPFE was not related to a higher mortality rate in univariate (hazard ratio [HR]: 1.04; 95% CI: 0.78-1.38, P = 0.799) or multivariate analysis (HR: 0.92; 95% CI: 0.68-1.26, P = 0.610). Conclusions: AE risk was higher in patients with CPFE and NSCLC, but all-cause mortality was not higher in patients with CPFE and NSCLC than in those with IPF and NSCLC. Physicians should be aware of the exaggerated risk of AE in patients with concomitant CPFE and NSCLC.
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( Sung Min Park ),( Gun Wook Kim ),( Hyun Ho Cho ),( Won Jeong Kim ),( Je Ho Mun ),( Margaret Song ),( Hoon Soo Kim ),( Byung Soo Kim ),( Moon Bum Kim ),( Hyun Chang Ko ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: Dermatologic diseases are generally managed on outpatient clinic and most of them show very low mortality. However, some severe dermatologic diseases are life- threatening. Objectives: To investigate the dermatological diseases leading to death and related factors. Methods: A retrospective study was conducted by reviewing medical records of patients who died in the dermatology ward, Pusan National University Hospital from 1998 to 2014. Patients`` demographics, their dermatologic diseases, immediate causes of death, comorbidities, and factors related death were investigated. Results: The total number of inpatients on dermatology during the study period was 3,142. Fourteen patients (6 males, and 8 females) expired while in hospital. The median age was 63.8 years (ranged 18 to 86), and the maximum number of death occurred in the age group more than 70 years old. Drug reaction was the most common underlying dermatologic disease, followed by bullous disease, generalized pustular psoriasis, dermatomyositis. Sepsis due to infection was the most common immediate cause of death. All patients had at least one comorbidities including hypertension, diabetes mellitus, kidney disease, and angina. Conclusion: Old age, comorbidities and septicemia were important factors which contributed to the mortality. Theintensive care is required during hospitalization in patients with severe dermatologic disease accompanying above risk factors.
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Automatic Welding Robot System for the Horizontal Position in the Shipyard
Sung Hoon Ko,Jeom Goo Kim,Hyeong Soon Moon 제어로봇시스템학회 2012 제어로봇시스템학회 국제학술대회 논문집 Vol.2012 No.10
In the horizontal position welding, a series of trials for automatic welding technique have been carried out. However, their results have been used under some limited scopes. In this study, a welding robot system was developed to automate the horizontal welding in ship building construction. The small mechanical robot incorporates CAN-communication based motor drivers to minimize wiring of the welding robot. In order to weld on various gaps between workpieces, an automatic gap measurement and an algorithm for weld pass design were developed. A database of optimum welding conditions for FCAW(flux cored arc welding) and GMAW(gas metal arc welding) process was also established. The developed welding robot system showed a good performance in the shop test, and it is being optimized in HHI shipyard.
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An analysis of characteristics of pigmented fungiform papillae of the tongue: single center study
( Sung-min Park ),( Tae-wook Kim ),( Hyun-joo Lee ),( Hyunju Jin ),( Hyang-suk Ryu ),( Woo-haing Shim ),( Gun-wook Kim ),( Byung-soo Kim ),( Hyun-chang Ko ),( Moon-bum Kim ),( Hoon-soo Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2
Background: Pigmented fungiform papillae of the tongue (PFPT) is a rare benign pigmentary disorder of the tongue. In dark-skinned individuals, PFPT appears to be relatively common. However, limited data exist on PFPT in Korean patients. Objectives: To investigate the clinical characteristics of PFPT in Korean patients Methods: Patients diagnosed with PFPT between 1995 and 2016 at Pusan National University Hospital were included. Clinical characteristics of PFPT, dermoscopic findings, and comorbidities were reviewed. Results: Eighteen patients diagnosed as PFPT were enrolled. Male to female ratio was 1 : 5. The mean age at diagnosis was 39.6 years (range, 8-65 years). According to Holzwanger’s classification, type I was the most common (88.9%). PFPT was commonly concomitant with pigmentary disorders including mucosal melanotic macules, Laugier-Hunziker syndrome, Melasma, and melanonychia (6/18, 33.3%). Preceding oral inflammatory lesions were found in 3 patients (16.7%), and systemic diseases and infectious diseases existed in 2 patients respectively (11.1%). Dermoscopic examination was performed in 7 patients; Pigmented border with dichotomized vessels (Rose petal pattern, 71.4%), and diffuse pigmentation (cobblestone pattern, 57.1%) were common findings. Conclusion: Our study shows PFPT can coexist with pigmentary disorder. Female predominance, concomitant pigmentary disorders of PFPT shows sex hormone or susceptibility to abnormal pigmentation may play a role in pathogenesis of PFPT.
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Moon, Kyung-Man,Lee, Myung-Hoon,Kim, Ki-Joon,Park, Guen-Hyun,Koh, Sung-Cheol 韓國海洋大學校 附設 海洋科學技術硏究所 2002 硏究論文集 Vol.11 No.1
We have investigated the differences between the general corrosion and microbiological influenced corrosion (MIC) of a steel in terms of electrochemical behavior and surface phenomena. Corrosion potential of a steel in medium solution without SRB (Sulphate Reducing Bacteria) shifted to a low direction continuously as a function of submerging time. The potential caused by MIC with SRB shifted to a noble direction after 20days' incubation, indication the growth of SRB biofilm and the test metal specimens and a formation of corrosion product. In addition, the color of medium inoculated with SRB changed from grey to black., the color change was observed in the medium without SRB inoculation. Moreover, corrosion rated of a steel in MIC were higher than those is the absence of SRB. This is probably because SRB caused be associated with the increasing corrosion rates through increasing cathodic reaction which caused the reducing sulfate to sulphide as well as formation of an oxygen concentration cell. The pitting corrosion was also observed in the of SRB inoculated medium.
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Clonogenic Assay of Gastric Adenocarcinoma Stem Cells
Moon, hee Sook,Kim, Boo Sung,Kim, Hoon Kyo,Kim, Dong Jip,Lee, kyung Shik,Moon, Hanlim CATHOLIC MEDICAL CENTER 1986 Bulletin of the Clinical Research Institute Vol.14 No.1
The clonogenic assay means culturing tumor stem cells, which are responsible for tumor growth by self renewal and differentiation to tumor end cells. Elimination of the malignant stem cells or their self renewal will lead cure of tumor. Thus, their behavior of the stem cells by the clonogenic assay has been correlated with prognosis and outcome of therapy. We studied the clonogenic assay by'means of double agar system for 21 patients with advanced stomach cancer. The colony formation evaluated on 14th day of the culture was grown from 14 of 19 malignant effusions plated and 1 of 2 tumor nodules plated. The number of the colonies ranged from 5 to 96 per petri dish, and the median number was 20. The plating efficiency ranged from 0.001 to 0.036%, and the median was 0.003%. In the morphologic studies, the colonies made of tightly packed cells were grown from the poorly differentiated adenocarcinoma, whereas the colonies made of loosely packed cells with mucin formation were grown from the mucin secreting adenocarcinoma of stomach. The chemosensitivity in vitro tests to cisplatin were performed in 5 patients, and the results showed 4 sensitive and 1 resistant patients. The result of in vivo study with instillation of intraperitoneal cisplatin revealed that 3 patients "in vitro sensitive" were "responsive in vivo", and 1 patient "in vitro resistant" was "non-responsive in vivo". We conclude that the clonogenic assay of stomach cancer is useful method to understand the biology of the stem cell pool and select proper chemotherapy according to the chemosensitivity test.
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Stochastic Integrated Generation and Transmission Planning Incorporating Electric Vehicle Deployment
Moon, Guk-Hyun,Kong, Seong-Bae,Joo, Sung-Kwan,Ryu, Heon-Su,Kim, Tae-Hoon The Korean Institute of Electrical Engineers 2013 Journal of Electrical Engineering & Technology Vol.8 No.1
The power industry is currently facing many challenges, due to the new environment created by the introduction of smart grid technologies. In particular, the large-scale deployment of electric vehicles (EVs) may have a significant impact on demand for electricity and, thereby, influence generation and transmission system planning. However, it is difficult to deal with uncertainties in EV charging loads using deterministic planning methods. This paper presents a two-stage stochastic decomposition method with Latin-hyper rectangle sampling (LHRS) to solve the integrated generation and transmission planning problem incorporating EV deployment. The probabilistic distribution of EV charging loads is estimated by Latin-hyper rectangle sampling (LHRS) to enhance the computational performance of the proposed method. Numerical results are presented to show the effectiveness of the proposed method.
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