Melittin-Conjugated Polymersomes Induce Anti-Tumor Activity Through Lysosomal Disruption

Jooho MOON,Youngheun CHO,Junhyung KIM,Hyonkoo HAN,Suhyeon PARK,Hyuncheol KIM 한국생물공학회 2023 한국생물공학회 학술대회 Vol.2023 No.10

Regulation of Tumor Microenvironment with Polymer-Modified Melittin

Jooho MOON,Jaeho OH,Hyuncheol KIM 한국생물공학회 2023 한국생물공학회 학술대회 Vol.2023 No.4

The Evolution of Internal IT Applications and e-Government Studies in Public Administration : Research Themes and Methods

Moon, M. Jae,Lee, Jooho,Roh, Chul-Young SAGE Publications 2014 ADMINISTRATION & SOCIETY Vol.46 No.1

<P>This study reviews research themes and methods used in information technology (IT) in government and e-government research. Although IT/e-government studies (including inward aspects of IT applications in government and e-government studies) continue to increase, they are not comprehensively understood as a subfield within public administration. Based on Rosenbloom’s three competing approaches to public administration (managerial, political, and legal), we investigated the major research themes of IT/e-government studies in public administration. We analyzed 248 IT/e-government articles published in six major public administration journals from 1965 to 2010 to examine IT/e-government research trends in terms of research themes and methods.</P>

스피드 스케이팅 500 m 스타트 구간의 운동역학적 분석

송주호 ( Jooho Song ),이돈형 ( Donhyung Lee ),문제헌 ( Jeheon Moon ) 한국스포츠정책과학원(구 한국스포츠개발원) 2017 체육과학연구 Vol.28 No.3

[목적] 본 연구의 목적은 스피드 스케이팅 500m 종목 스타트 구간에서 한국 국가대표선수들과 해외 우수선수들의 기술동작과 파워를 비교하여 경기력 향상을 위한 방안을 제시하고 기록에 영향을 미치는 운동역학적 변인들의 관계를 파악하는 것이다. [방법] 연구대상자는 한국 국가대표 스피드 스케이팅 8명(한국선수), 해외스피드 스케이팅 선수 6명(해외선수)이다. 3차원 동작분석을 위하여 고속카메라 5대를 동원하여 국제대회에 참가한 선수들의 스타트 동작 40 m 구간을 촬영하였다. 분석변인은 키네메틱 체인, 100 m 네트 시간, 9 스트로크까지 소요시간, 스타트 2.5 sec 후 신체중심의 이동거리, 신체중심의 속도, 상체각도 가동범위, 무릎관절 각도 가동범위, 푸시오프 각도 가동범위, 정미 파워 출력, 총 파워 손실로 정하였다. [결과] 한국선수의 올바른 키네메틱 체인 비율은 61.2%로 해외선수의 76.0% 보다 낮았다. 9 스트로크까지 소요시간에서는 한국선수들이 2.82±0.25 sec로 해외선수들 2.53±0.11 sec 보다 통계적으로 유의하게 높았다(p=.001). 푸시오프 각도의 가동범위는 한국선수들이 60.15±2.75°로 해외선수들의 64.76±2.55° 보다 통계적으로 유의하게 낮았다(p=.001). 정미 파워 출력은 한국선수들이 887.2±269.9 W로 해외선수들의 1103±264.1 W 보다 통계적으로 유의하게 낮았다(p=.021). 100 m 네트 시간과 관련이 있는 요인은 2.5 sec 후 신체중심의 이동거리(r=-.956, p=.001), 정미 파워 출력(r=-.931, p=.001), 총 파워 손실(r=-.904, p=.001)이다. [결론] 한국선수들의 스타트 구간 기록 향상을 위해서는 올바른 키네메틱 체인을 구사할 수 있는 기술훈련을 통하여 스케이팅의 효율을 극대화해야 한다. 또한 100 m 네트시간과 관련이 있는 정미 파워 출력이 해외선수 들에 비해 낮은 결과로 나타났기 때문에 하지 근 파워를 향상시킬 수 있는 훈련을 도입해야 할 것이다. [Purpose] The purpose of this study was to compare the technique and power of the Korean national athletes and international athletes in the start phase of the 500 m speed skating to improve the performance and to understand the relationship between the biomechanical variables affecting the record. [Method] The subjects were 8 Korean national athletes (Korean athletes) and 6 international athletes (international athletes). For the three dimensional motion analysis, 5 high-speed cameras were used to capture the 40 m start phase of the athletes participating in the international competition. The variables selected for analysis were the kinematic chain, 100 m net time, time to 9 strokes, horizontal position of center of mass after 2.5 sec, range of motion of trunk, knee, push-off angle, net power output, total power loss. [Results] The correct kinematic chain ratio of Korean athletes was 61.2%, which was lower than 76.0% of international athletes. The time to 9 strokes was 2.82±0.25 sec for Korean athletes, which was significantly lower than 2.53±0.11 sec for international athletes (p=.001). The range of motion of the push-off angle was 60.15±2.75° for Korean athletes, which was significantly lower than 64.76±2.55° for international athletes (p=.001). The net power output was 887.2±269.9 W for Korean players and 1103±264.1 W for international players (p=.021). The variables related to the 100 m net time were the horizontal position of center of mass after 2.5 sec (r=-.956, p=.001), the net power output (r=-.931, p=.001), and the total power loss (r=-.904, p=.001). [Conclusion] In order to improve the start performance of Korean athletes, it is necessary to maximize the efficiency of skating through skill training to use the correct kinematic chain. Also power enhancement training is needed to improve leg power because the net power output related with 100 m net time.

Crack-Release Transfer Method of Wafer-Scale Grown Graphene Onto Large-Area Substrates

Lee, Jooho,Kim, Yongsung,Shin, Hyeon-Jin,Lee, ChangSeung,Lee, Dongwook,Lee, Sunghee,Moon, Chang-Yul,Lee, Su Chan,Kim, Sun Jun,Ji, Jae Hoon,Yoon, Hyong Seo,Jun, Seong Chan American Chemical Society 2014 ACS APPLIED MATERIALS & INTERFACES Vol.6 No.15

<P>We developed a crack-release graphene transfer technique for opening up possibilities for the fabrication of graphene-based devices. Graphene film grown on metal catalysts/SiO<SUB>2</SUB>/Si wafer should be scathelessly peeled for sequent transferring to a target substrate. However, when the graphene is grown on the metal catalyst on a silicon substrate, there is a large tensile stress resulting from the difference of the coefficient of thermal expansion in the catalyst and silicon. The conventional methods of detaching graphene from metal catalysts were found to induce considerable mechanical damage on graphene films during separation processes including metal wet etching. Here we report a new technique wherein bubbles generated by electrolysis reaction separate thin metal catalysts from the SiO<SUB>2</SUB>/Si wafer. The dry attachment of graphene to the target wafer was processed utilizing a wafer to wafer bonding technique in a vacuum. We measured the microscopic image, Raman spectra, and electrical properties of the transferred graphene. The optical and electrical properties of the graphene transferred by the bubbles/dry method are better than those of the graphene obtained by mechanical/wet transfer.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2014/aamick.2014.6.issue-15/am502565z/production/images/medium/am-2014-02565z_0005.gif'></P>

Highly Conductive Ink Jet Printed Films of Nanosilver Particles for Printable Electronics

Kim, Dongjo,Moon, Jooho The Electrochemical Society 2005 Electrochemical and solid-state letters Vol.8 No.11

Rapid advances in antimony triselenide photocathodes for solar hydrogen generation

Yang, Wooseok,Moon, Jooho The Royal Society of Chemistry 2019 Journal of materials chemistry. A, Materials for e Vol.7 No.36

<P>One of the paramount challenges for realizing practical solar hydrogen production is the development of a low-cost semiconductor that is suitable for large-area and high-performance photoelectrochemical devices. Antimony triselenide (Sb2Se3) has emerged as a nearly ideal semiconductor material that satisfies nearly all requirements for effectively generating hydrogen using solar energy. In this report, we highlight the extraordinary characteristics of Sb2Se3 relative to the myriad of other emerging semiconductors, in terms of cost, band gap, optoelectronic properties, photocorrosion stability, and processability. Additionally, we discuss recent studies on Sb2Se3 photocathodes with a focus on their intrinsic properties, use of co-catalysts, and top and bottom interface engineering for enhanced performance. Unresolved issues and future research directions will also be discussed briefly. We believe that the rapid advances in Sb2Se3-photocathode water splitting over the past three years suggest a positive outlook for the cost-effective production of solar hydrogen.</P>

Low-temperature, solution-processed metal oxide thin film transistors

Jeong, Sunho,Moon, Jooho The Royal Society of Chemistry 2012 Journal of materials chemistry Vol.22 No.4

<P>High-performance, solution-processable semiconductors have drawn significant attention for use in low-cost, functional electronic applications. Metal oxide semiconductors are the most promising building blocks for high performance electronic devices because of their electrical properties and solution-processability. However, the major impediment for metal oxide semiconductors is that the electrical properties applicable to electronic devices are activated by chemical/physical structural evolution at high temperatures, which critically limits the practical applications. This article reviews the recent progress in the development of high-performance oxide semiconductors processed at low temperatures which are compatible with plastic substrates and discusses the chemical/physical approaches to lower the annealing temperature.</P> <P>Graphic Abstract</P><P>Metal oxide semiconductors are the most promising building blocks to facilitate the development of high-performance, low-cost electronic devices. The recent progress in resolving the major downfall of metal oxide semiconductors, a high annealing temperature, has yielded high-performance oxide semiconductors processed at low temperature that are even compatible with plastic substrates. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c1jm14452a'> </P>

Development of Lipid Based Nanodrill Antibiotic Inducing Membrane Disturbance

Youngheun CHO,Jooho MOON,Hyuncheol KIM 한국생물공학회 2022 한국생물공학회 학술대회 Vol.2022 No.9

확률적 설계 기법을 적용한 하이브리드 로켓 모터의 신뢰성 분석

문근환(Keunhwan Moon),김완범(Wanbeom Kim),이정표(Jungpyo Lee),최주호(Jooho Choi),김진곤(Jinkon Kim) 한국추진공학회 2013 한국추진공학회 학술대회논문집 Vol.2013 No.5

본 연구에서는 확률적 설계 기법을 적용하여 하이브리드 로켓 모터의 신뢰성 분석을 수행하였다. 하이브리드 로켓 모터의 신뢰성 분석을 위해서 실험을 통해 측정된 실험값을 사용하여 입력 변수의 확률적 특성을 모델링 하였다. 이 결과 추력을 확률분포로 구할 수 있었으며, 실제 측정치가 예측한 확률분포의 95% 신뢰구간 내에 있는 것을 확인 할 수 있었다. In this study, reliability analysis is conducted for hybrid rocket motor performance using probabilistic design method. Experimental data are used to model the probability distributions of the input parameters of the equations in the performance evaluation. As a result, distribution of the thrust is predicted and validated by the measured thrust under the 95% confidence level.