Vitamin C restores ovarian follicular reservation in a mouse model of aging

Mohammad-Amin Abdollahifar,Nahid Azad,Ensieh Sajadi,Zahra Shams Mofarahe,Fatemeh Zare,Ali Moradi,Fatereh Rezaee,Mohammad Gholamin,Shabnam Abdi 대한해부학회 2019 Anatomy & Cell Biology Vol.52 No.2

Ovarian aging is related to the reduction of oocyte quality and ovarian follicles reservation leading to infertility. Vitamin C is a natural antioxidant which may counteract with adverse effects of aging in the ovary. The aim of this study was to evaluate the possible effect of vitamin C on NMRI mice ovarian aging according to the stereological study. In this experimental study, 36 adult female mice (25–30 g) were divided into two groups: control and vitamin C. Vitamin C (150 mg/kg/day) were administered by oral gavage for 33 weeks. Six animals of each group were sacrificed on week 8, 12, and 33, and right ovary samples were extracted for stereology analysis. Our data showed that the total volume of ovary, cortex, medulla and corpus luteum were significantly increased in vitamin C group in comparison to the control groups (P≤0.05). In addition, the total number of primordial, primary, secondary, and antral follicles as well as granulosa cells were improved in vitamin C group in compared to the control groups (P≤0.05). No significant difference was observed in total volume of oocytes in antral follicles between control and vitamin C groups. Our data showed that vitamin C could notably compensate undesirable effects of ovarian aging in a mouse model.

Assessment of Soil Chemical Properties (EC, SAR, pH) in Downstrems of a Qanat and Well (case Study: Meibod)

Mohammad Hossein Mokhtari,Mohammad Zare Ernani,Mohammad Ali Hakim Zadeh,Safoora Kargar Shoruki 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Efficacy and Safety of Low-Dose-Rate Endorectal Brachytherapy as a Boost to Neoadjuvant Chemoradiation in the Treatment of Locally Advanced Distal Rectal Cancer: A Phase-II Clinical Trial

Mohammad Mohammadianpanah,Shapour Omidvari,Shadi Zohourinia,Mansour Ansari,Leila Ghahramani,Mohammad Zare-Bandamiri,Ahmad Mosalaei,Niloofar Ahmadloo,Saeedeh Pourahmad,Hamid Nasrolahi,Sayed Hasan Hamed 대한대장항문학회 2015 Annals of Coloproctolgy Vol.31 No.4

Purpose: Despite advances in rectal cancer treatment over the last decade, local control and risk of late side effects due to external beam radiation therapy (EBRT) remain as concerns. The present study aimed to investigate the efficacy and the safety of low-dose-rate endorectal brachytherapy (LDRBT) as a boost to neoadjuvant chemoradiation for use in treating locally advanced distal rectal adenocarcinomas. Methods: This phase-II clinical trial included 34 patients (as the study arm) with newly diagnosed, locally advanced (clinical T3–T4 and/or N1/N2, M0) lower rectal cancer. For comparative analysis, 102 matched patients (as the historical control arm) with rectal cancer were also selected. All the patients were treated with LDRBT (15 Gy in 3 fractions) and concurrent chemoradiation (45–50.4 Gy). Concurrent chemotherapy consisted of oxaliplatin 130 mg/m2 intravenously on day 1 plus oral capecitabine 825 mg/m2 twice daily during LDRBT and EBRT. Results: The study results revealed a significant differences between the study arm and the control arm in terms in the pathologic tumor size (2.1 cm vs. 3.6 cm, P = 0.001), the pathologic tumor stage (35% T3–4 vs. 65% T3–4, P = 0.003), and the pathologic complete response (29.4% vs. 11.7%, P < 0.028). Moreover, a significantly higher dose of EBRT (P = 0.041) was found in the control arm, and a longer time to surgery was observed in the study arm (P < 0.001). The higher rate of treatment-related toxicities, such as mild proctitis and anemia, in the study arm was tolerable and easily manageable. Conclusion: A boost of LDRBT can optimize the pathologic complete response, with acceptable toxicities, in patients with distal rectal cancer.

Predictors of Hepatitis B Preventive Behavioral Intentions in Healthcare Workers

Mohammad ali Morowatishaifabad,Mohammad Javad Zare Sakhvidi,Mahdi Gholianavval,Darioush Masoudi Boroujeni,Mahdi Mirzaei Alavijeh 한국산업안전보건공단 산업안전보건연구원 2015 Safety and health at work Vol.6 No.2

Background: Healthcare workers’ practices regarding hepatitis B have an important effect on the control of this problem in workplaces. Methods: A questionnaire-based cross-sectional study was used to investigate the role of knowledge, cues to action, and risk perceptions as predictors of preventive behavioral intentions for hepatitis B among healthcare works in Broujen, Iran (n ¼ 150). History of hepatitis B vaccination, hepatitis B surface antigen test, and demographic characteristics were investigated. The psychometric properties of the questionnaire were established. Results: Those who had a history of hepatitis B surface antigen test had a statistically significant higher level of risk perceptions (30.89 4.08 vs. 28.41 3.93, p < 0.01) and preventive behavioral intentions (5.05 1.43 vs. 4.45 1.29, p < 0.01). The mean score of cues to action was significantly correlated with age and work history (r ¼ 0.20, p ¼ 0.02 and r ¼ 0.19, p ¼ 0.02). Preventive behavioral intentions were significantly correlated with cues to action and risk perceptions but not with knowledge level. Cognitional factors were responsible for a 17% change in observed variance of preventive behavioral intentions, which was statistically significant. Conclusion: Risk perceptions were the most important determinant of preventive behavioral intentions for hepatitis B among health personnel; thus, emphasizing risk perceptions is recommended in educational programs aimed at increasing health personnel’s practices regarding hepatitis B.

Effects of extrusion of rice bran on performance and phosphorous bioavailability in broiler chickens

Zare-Sheibani, Ali Akbar,Arab, Masoud,Zamiri, Mohammad Javad,Rezvani, Mohammad Reza,Dadpasand, Mohammad,Ahmadi, Farhad Korean Society of Animal Science and Technology 2015 한국축산학회지 Vol.57 No.7

Background: Rice bran is a by-product of the rice-milling process, which remains largely underutilized; however, efficient processing treatments may improve its feeding value for chickens. This is of great economic and environmental importance, as this can lower the production costs, and offer an opportunity for valorization of a low-quality agricultural by-product, to a high-value feed source. Methods: This experiment was conducted to study the effect of extruded rice bran on performance and phosphorous (P) bioavailability in broiler chickens. In a completely randomized design, 200 seven-day-old broilers (Cobb 500) were allotted to five treatments with five replicates per treatment and 8 chicks per replicate, and fed with their respective diet during the starter (8 to 21 days) and grower (22 to 42 days) periods. Diets were a basal corn-soybean based diet (T1), or diets containing 20 % rice bran (T2), 30 % rice bran (T3), 20 % extruded rice bran (T4), or 30 % extruded rice bran (T5). Results: Birds feeding on T4 and T5 diets had a higher body weight gain and lower feed-to-gain ratio compared to those feeding on T2 and T3 diets (p < 0.05). Birds receiving diets containing extruded rice bran had higher total P availability and tibia ash content, as compared with those receiving diets containing un-extruded rice bran (p < 0.05). Relative weight of the pancreas was higher in birds receiving T2 and T3 diets. Conclusions: The results confirmed the beneficial effect of extrusion treatment of rice bran on performance and P availability in broilers. Up to 30 % extruded rice bran may be included in the broiler diet without apparent adverse effects on the performance.

Mixed-pairing superconductivity in 5d Mott insulators with antisymmetric exchange: Application to Sr2IrO4

Zare, Mohammad-Hossein,Biderang, Mehdi,Akbari, Alireza American Physical Society 2017 Physical Review B Vol.96 No.20

<P>We study the symmetry of the potential superconducting order parameter in 5d Mott insulators with an eye toward hole-doped Sr2IrO4. Using a mean-field method, a mixed singlet-triplet superconductivity, d + p, is observed due to the antisymmetric exchange originating from a quasi-spin-orbit coupling. Our calculation on ribbon geometry shows the possible existence of the topologically protected edge states, because of the nodal structure of the superconducting gap. These edge modes are spin polarized and emerge as zero-energy flat bands, supporting a symmetry-protected Majorana state, verified by evaluation of the winding number and Z(2) topological invariant. At the end, a possible experimental approach for observation of these edge states and determination of the superconducting gap symmetry is discussed based on the quasiparticle interference technique.</P>

Determining potential habitat of Kermani Calligonum and Lentil Bead Salmaki in Sistan region of south eastern Iran

Mohammad Reza Moradi,Iraj Amiri,Mohammad Zare,Hassan Fathizad 대한공간정보학회 2017 Spatial Information Research Vol.25 No.2

In this study, potential habitat of two species, Kermani Calligonum and Lentil Bead Salmaki in Sistan region was determined by using geographic information system and measurements of distance techniques. For intraregional study, five habitants were randomly selected and in every location, 10 soil profiles were dug to a depth of 45 cm and soil samples were taken. According to samples taken in each profile parameters such as EC, texture, pH and organic matter in soil other physical parameters at each site such as altitude, temperature, evaporation, results show that Lentil Bead Salmaki in comparison with Kermani Calligonum is able to grow in soils with high salinity, less organic matter and soils with light texture and also tends to thrive and grow in acid soils. Finally, by combining different layers of information for each species, it was found that from total study area of 653,345 ha, three regions including 45,896 ha (7.02%) were suitable for growing Kermani Calligonum. 29,446 ha (4.5%) of this area belongs to habitat of Kermani Calligonum. Approximately remaining 16,450 acres (2.25% of the total area), is potential habitat and the results also indicated that three areas consisting of 8223 ha (1.25%) is suitable for Lentil Bead Salmaki growth. 1962 ha (0.3%) of this area belongs to Lentil Bead Salmaki habitat and the remaining 7546 ha (0.95%) is the area of potential habitat. The accuracy of determining the habitat (finding location) of the mentioned species is estimated to be over 95%.

Design of ionic liquid 1,3-disulfonic acid imidazolium hydrogen sulfate as a dual-catalyst for the one-pot multi-component synthesis of 1,2,4,5-tetrasubstituted imidazoles

Mohammad Ali Zolfigol,Ardeshir Khazaei,Ahmad Reza Moosavi-Zare,Abdolkarim Zare,Zhila Asgari,Vahid Khakyzadeh,Alireza Hasaninejad 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.3

Novel ionic liquid 1,3-disulfonic acid imidazolium hydrogen sulfate {[Dsim]HSO4} efficiently catalyzes the synthesis of 1,2,4,5-tetrasubstituted imidazoles via the one-pot multi-component condensation of benzyl with aldehydes, primary amines and ammonium acetate at 90 8C under solvent-free conditions. Dual hydrogen-bond donors can be used to direct the assembly of this catalyst and the efficiency of it.

Factors Affecting Survival in Patients with Colorectal Cancer in Shiraz, Iran

Zare-Bandamiri, Mohammad,Khanjani, Narges,Jahani, Yunes,Mohammadianpanah, Mohammad Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.1

Background: Colorectal cancer (CRC) is the third most common cancer in the world, and the fourth in Iran in both genders. The aim of this study was to find predictive factors for CRC survival. Materials and Methods: Medical records of 570 patients referred to the radiotherapy oncology department of Shiraz Namazi hospital from 2005 to 2010 were retrospectively analysed. Data were collected by reviewing medical records, and by telephone interviews with patients. Survival analysis was performed using the Cox's regression model with survival probability estimated with Kaplan-Meier curve. The log-rank test was used to compare survival between strata. Data was analyzed with Stata 12. Results: The five-year survival rate and the mean survival time after cancer diagnosis were 58.5% and $67{\pm}4months$. On multivariate analysis, age of diagnosis, disease stage and primary tumor site, lymphovascular invasion and type of treatment (in colon cancer) were significant factors for survival. Conclusions: Age of diagnosis and type of treatment (adjuvant therapy in patients with colon cancer) were two modifiable factors related to survival of CRC patients. Therefore earlier diagnosis might help increase survival.

k-anonymity Diagnosis Centre

Mohammad Reza Zare Mirakabad,Aman Jantan,Stephane Bressan 보안공학연구지원센터 2009 International Journal of Security and Its Applicat Vol.3 No.1

Many efforts have been done in the field of privacy preservation to devise algorithms for data k-anonymization and l-diversification trying to protect privacy, by modification of data, for example. Fewer efforts have been made for devising techniques, tools and methodologies for investigation and evaluation of privacy risks. We are concerned about privacy diagnosis before starting protection. Actually we show privacy leakages threaten data publication. We introduce a Privacy Diagnosis Centre for this purpose. In this paper toward this diagnosis centre we focus on anonymity and, in particular, k-anonymity. Then we aim at k-anonymity diagnosis system. Such a system explores various questions about k-anonymity of data. “For which k is my data k-anonymous?”, “is my data sufficiently k-anonymous?”, “which subset and projection of data can be safely published to guarantee given k?”, “which information, if available from an outside source, threatens the k-anonymity of my data?” are examples of questions can be answered. We leverage two properties of k-anonymity that we express in the form of two lemmas. The first lemma is a monotonicity property that enables us to adapt the a-priori algorithm for k-anonymity. The second lemma, however, is a determinism property that enables us to devise an efficient algorithm for δ-suppression. We illustrate and empirically analyze the performance of the proposed algorithms.