Socioeconomic Disparities in Colorectal Cancer Screening in Korea : A Nationwide Cross-Sectional Study

Suh, Mina,Choi, Kui Son,Lee, Hoo-Yeon,Hahm, Myung-Il,Lee, Yoon Young,Jun, Jae Kwan,Park, Eun-Cheol Wolters Kluwer Health 2015 Medicine Vol.94 No.39

<P><B>Abstract</B></P><P>Colorectal cancer (CRC) is a common cancer worldwide. The incidence and mortality rates of CRC are higher among lower socioeconomic status (SES) populations.</P><P>We investigated the association between different indicators of SES and CRC screening rates in Korea. The eligible study population included males and females aged 50 to 74 years who participated in a nationwide cross-sectional survey (2010–2012). The “compliance with recommendation” category was applicable to participants who had undergone a fecal occult blood test (FOBT), double-contrast barium enema, or colonoscopy within 1, 5, or 10 years, respectively.</P><P>In total, 6221 subjects (51.4% female, 55.6% aged 50 years) were included in the final analysis. Lower household income was significantly negatively related to compliance with screening recommendations (<I>P</I> for trend < 0.01) and marginally significantly related to noncompliance with recommendations (<I>P</I> for trend = 0.07). Older age and poor self-reported health were associated with the screening rate using the FOBT; male sex, older age, higher household income, having supplemental insurance, family history of cancer, and poor self-reported health were associated with a higher screening rate using colonoscopy.</P><P>Lower household income was associated with a higher screening rate using the FOBT and with a lower screening rate using colonoscopy. To increase the rate of CRC screening using colonoscopy, efforts should be made toward improving the education and promotion of screening to the low household income target population.</P>

Prevalence of Allergic Diseases among Korean School-age Children: A Nationwide Cross-Sectional Questionnaire Study

Suh, Mina,Kim, Ho-Hyun,Sohn, Myung Hyun,Kim, Kyu-Earn,Kim, Changsoo,Shin, Dong Chun The Korean Academy of Medical Sciences 2011 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.26 No.3

<P>The purpose of this study was to investigate the nationwide prevalence of childhood asthma, eczema and other allergic diseases in Korean school-age children (8-11 yr old) and to assess the difference between residential areas. Among 6,279 elementary schools, 427 schools were randomly selected according to residential area (metropolitan, provincial, rural, and industrial area) by the cluster sampling method. Parents of students completed a modified Korean version of a questionnaire formulated by the International Study of Asthma and Allergies in Childhood (ISAAC). Among 50,200 subjects, 31,026 (61.8%) responded, and 30,893 (99.6%) were analyzed. The 12-month prevalence of wheeze, flexural rash, and allergic rhinitis symptoms were 4.8%, 15.3%, and 32.9%, respectively. The prevalence of diagnosis of allergic diseases in boys was higher than that in girls, with the exception of eczema. In both boys and girls, the difference of the prevalence of allergic diseases among industrial, metropolitan and provincial areas was not statistically significant, but the differences between rural area and other areas were significant. Our results support the importance of contextual effect associated with residential area as causative agents of allergic diseases among Korean school-age children.</P>

Cancer Screening in Korea, 2012: Results from the Korean National Cancer Screening Survey

Suh, Mina,Choi, Kui Son,Lee, Yoon Young,Park, Boyoung,Jun, Jae Kwan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

We investigated the cancer screening rates for five types of cancer (stomach, liver, colorectal, breast, and cervix uteri) using data from the Korean National Cancer Screening Survey (KNCSS), which is a nationwide, annual cross-sectional survey. The eligible study population included cancer-free men 40 years of age and older and women 30 years of age and older. The lifetime screening rate and screening rate with recommendation were calculated. The lifetime screening rates for gastric, liver, colorectal, breast, and cervical cancers were 77.9%, 69.9%, 65.8%, 82.9%, and 77.1%, respectively. The screening rates with recommendation were 70.9%, 21.5%, 44.7%, 70.9%, and 67.9%, respectively. The most common reason for all types of cancer was "no symptoms", followed by "lack of time" and "fear of the examination procedure". Efforts to facilitate participation in liver and colorectal cancer screening among Korean men and women are needed.

Trends in Participation Rates for the National Cancer Screening Program in Korea, 2002-2012

Suh, Mina,Song, Seolhee,Cho, Ha Na,Park, Boyoung,Jun, Jae Kwan,Choi, Eunji,Kim, Yeol,Choi, Kui Son Korean Cancer Association 2017 Cancer Research and Treatment Vol.49 No.3

<P><B>Purpose</B></P><P>The National Cancer Screening Program (NCSP) in Korea supports cancer screening for stomach, liver, colorectal, breast, and cervical cancer. This study was conducted to assess trends in participation rates among Korean men and women invited to undergo screening via the NCSP as part of an effort to guide future implementation of the program in Korea.</P><P><B>Materials and Methods</B></P><P>Data from the NCSP for 2002 to 2012 were used to calculate annual participation rates with 95% confidence intervals (CI) by sex, insurance status, and age group for stomach, liver, colorectal, breast, and cervical cancer screening.</P><P><B>Results</B></P><P>In 2012, participation rates for stomach, liver, colorectal, breast, and cervical cancer screening were 47.3%, 25.0%, 39.5%, 51.9%, and 40.9%, respectively. The participation rates increased annually by 4.3% (95% CI, 4.0 to 4.6) for stomach cancer, 3.3% (95% CI, 2.5 to 4.1) for liver cancer, 4.1% (95% CI, 3.2 to 5.0) for colorectal cancer, 4.6% (95% CI, 4.1 to 5.0) for breast cancer, and 0.9% (95% CI, –0.7 to 2.5) for cervical cancer from 2002 to 2012.</P><P><B>Conclusion</B></P><P>Participant rates for the NCSP for the five above-mentioned cancers increased annually from 2002 to 2012.</P>

Predictive value of sperm motility before and after preparation regarding pregnancy outcome of intrauterine insemination cycle: a retrospective cohort study

( Mina Jeong ),( Hoon Kim ),( Seung Yup Ku ),( Chang Suk Suh ),( Seok Hyun Kim ),( Young Min Choi ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-

Objective: To investigate the value of sperm motility before and after preparation for predicting pregnancy outcome in couples with intrauterine insemination (IUI) cycles. Methods: This retrospective cohort study included 187 infertile couples who underwent 300 IUI cycles with ovarian stimulation from January 2012 to December 2017 at a single tertiary center. Patients with severe endometriosis or severe male factor infertility were excluded from analysis. The main outcomes measured were clinical pregnancy and live birth. Sperm characteristics, especially motility before and after sperm preparation on insemination day, were assessed and compared according to the pregnancy outcome. Results: Overall clinical pregnancy rate was 15.3% and live birth rate was 10.3%. Patient and cycle characteristics were not significantly different according to the pregnancy outcome. Initial or inseminated total motile sperm count (TMC), and post-preparation sperm motility showed no significant difference according to the pregnancy outcome. Sperm motility (%) before preparation was significantly higher in patients with live birth than in those without live birth (71.60 ± 12.58 vs. 67.27 ± 11.68, p<.05). Probably in the same vein, change of the sperm motility through preparation process was significantly less in patients with live birth than in those without live birth. These relationships were still significant after adjusting for confounding variables such as female age or level of Anti-Mullerian hormone (AMH). According to the logistic regression analysis, predicted odds of live birth was the greatest when pre-preparation sperm motility was at least 75% (aOR=2.686, 95% CI: 1.222-5.902). Conclusion: Motility of the inseminated sperm dose not reliably predict the pregnancy outcome in intrauterine insemination cycles. Sperm motility before preparation, especially when higher than 75%, predicts the probability of live birth fairly well regardless of the degree of improvement in motility before and after sperm preparation.

Improving Diagnostic Performance of MRI for Temporal Lobe Epilepsy With Deep Learning-Based Image Reconstruction in Patients With Suspected Focal Epilepsy

Suh Pae Sun,Park Ji Eun,Roh Yun Hwa,Kim Seonok,Jung Mina,Koo Yong Seo,Lee Sang-Ahm,Choi Yangsean,Kim Ho Sung 대한영상의학회 2024 Korean Journal of Radiology Vol.25 No.4

Objective: To evaluate the diagnostic performance and image quality of 1.5-mm slice thickness MRI with deep learningbased image reconstruction (1.5-mm MRI + DLR) compared to routine 3-mm slice thickness MRI (routine MRI) and 1.5-mm slice thickness MRI without DLR (1.5-mm MRI without DLR) for evaluating temporal lobe epilepsy (TLE). Materials and Methods: This retrospective study included 117 MR image sets comprising 1.5-mm MRI + DLR, 1.5-mm MRI without DLR, and routine MRI from 117 consecutive patients (mean age, 41 years; 61 female; 34 patients with TLE and 83 without TLE). Two neuroradiologists evaluated the presence of hippocampal or temporal lobe lesions, volume loss, signal abnormalities, loss of internal structure of the hippocampus, and lesion conspicuity in the temporal lobe. Reference standards for TLE were independently constructed by neurologists using clinical and radiological findings. Subjective image quality, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were analyzed. Performance in diagnosing TLE, lesion findings, and image quality were compared among the three protocols. Results: The pooled sensitivity of 1.5-mm MRI + DLR (91.2%) for diagnosing TLE was higher than that of routine MRI (72.1%, P < 0.001). In the subgroup analysis, 1.5-mm MRI + DLR showed higher sensitivity for hippocampal lesions than routine MRI (92.7% vs. 75.0%, P = 0.001), with improved depiction of hippocampal T2 high signal intensity change (P = 0.016) and loss of internal structure (P < 0.001). However, the pooled specificity of 1.5-mm MRI + DLR (76.5%) was lower than that of routine MRI (89.2%, P = 0.004). Compared with 1.5-mm MRI without DLR, 1.5-mm MRI + DLR resulted in significantly improved pooled accuracy (91.2% vs. 73.1%, P = 0.010), image quality, SNR, and CNR (all, P < 0.001). Conclusion: The use of 1.5-mm MRI + DLR enhanced the performance of MRI in diagnosing TLE, particularly in hippocampal evaluation, because of improved depiction of hippocampal abnormalities and enhanced image quality.

Diverse Patterns of Perilymphatic Space Enhancement in the Rat Inner Ear after Intratympanic Injection of Two Different Types of Gadolinium: A 9.4-Tesla Magnetic Resonance Study

Park, Mina,Lee, Ho Sun,Choi, Jun-Jae,Kim, Hyeonjin,Lee, Jun Ho,Oh, Seung Ha,Suh, Myung-Whan S. Karger AG 2015 Audiology & neuro-otology Vol.20 No.2

<P>Abstract</P><P><B><I>Objective:</I></B> To compare the quality of perilymphatic enhancement in the rat inner ear after intratympanic injection of two types of gadolinium with a 9.4-tesla micro-MRI. <B><I>Materials and Methods:</I></B> Gadolinium was injected into the middle ear in 6 Sprague-Dawley rats via the transtympanic route. The left ear was injected with Gd-DO3A-butrol first, and then the right ear was injected with Gd-DOTA. MR images of the inner ear were acquired 1.0, 1.5, 2.0, 2.5, 3.0, 3.5, and 4 h after intratympanic (IT) injection using an Agilent MRI system 9.4T/160/AS. The normalized signal intensity was quantitatively analyzed at the scala vestibuli (SV), scala media, and scala tympani (ST) using a Marosis M-view system. Then the normalized signal intensities (SIs) were compared between the two contrast agents. <B><I>Results:</I></B> For Gd-DO3A-butrol, the SI was as low as 1.0-1.5 throughout 1-4 h at the SV and ST of the basal turn. The maximum SI was 1.5 ± 0.5 at the SV (2 h) and 1.3 ± 0.5 at the ST (2 h). For Gd-DOTA, the 1-hour postinjection SI at the basal turn was 2.5 ± 0.5 at the SV, 1.6 ± 0.3 at the ST, and 1.2 ± 0.3 at the scala media. In the apical turn, the maximum SI was reached after 2.5 h. The maximum SI in the apical turn was 1.8 ± 0.4 at the SV (3.5 h), 1.8 ± 0.4 at the ST (4 h), and 1.4 ± 0.3 at the scala media (4 h). <B><I>Conclusions:</I></B> We were able to clearly visualize and separate the ST and SV using IT Gd and 9.4-tesla micro-MRI. We recommend using Gd-DO3A-butrol over Gd-DOTA and to perform the MRI 2.5 h after using IT Gd in the rat inner ear.</P><P>© 2015 S. Karger AG, Basel</P>

Multimodal Imaging Findings of Cerebral Amyloid Angiopathy Related Inflammation With Unusual Clinical Manifestation: A Case Report

Jalim Koo,Mina Park,Han Soo Yoo,Bio Joo,Sung Jun Ahn,Jae-Hoon Lee,Young Hoon Ryu,Sang Hyun Suh 대한자기공명의과학회 2023 Investigative Magnetic Resonance Imaging Vol.27 No.1

Cerebral amyloid angiopathy-related inflammation (CAA-RI) is a rare encephalopathy characterized by the coexistence of a perivascular inflammatory reaction in patients with cerebral amyloid angiopathy. CAA-RI diagnosis is challenging as its final diagnosis requires invasive procedures such as autopsy or brain biopsy. Therefore, multimodal imaging approaches with clinical considerations are essential for the probable diagnosis of CAA-RI. In particular, in the case of CAA-RI presented with uncommon clinical symptoms, the need for imaging in diagnosis is further highlighted by difficulties of clinical approaches. Herein, we report a case of CAA-RI with unusual clinical manifestation diagnosed using multimodal imaging including magnetic resonance imaging (MRI) and amyloid positron emission tomography-computed tomography (PET-CT). Multimodal imaging approaches using adequate MRI sequences and PET-CT scans could facilitate the diagnosis of CAA-RI without requiring invasive pathological confirmation.

도금용 억제제가 도금 구리 박막의 반사율에 미치는 영향

서호영(Hoyoung Suh),허미나(Mina Heo),홍기민(Kimin Hong) 한국물리학회 2022 새물리 Vol.72 No.5

구리도금용 전해액에 유기첨가제인 Ralufon#14을 가하여 평판 구리 박막을 제작하고 구리 박막의 결정구조, 입도, 비저항, 표면거칠기 및 반사계수를 분석하였다. 전해액만으로 도금한 구리 박막에 비해 Ralufon#14을 첨가하면 구리의 결정성과 표면거칠기가 변화하며 비저항이 크게 감소한다. 또한 순수 전해액으로만 제작한 구리 박막과 비교하였을 때 Ralufon#14를 첨가하여 제작한 구리 박막의 반사계수는 크게 증가한다. Ralufon#14의 첨가 여부는 도금 구리 박막의 물성에는 큰 변화를 야기하지만 그 변화는 Ralufon#14의 농도에는 의존하지 않는다. We have fabricated copper thin films by using an electroplating method. Specifically, we added an organic additive, Ralufon#14, in the plating electrolyte and observed the variation of the material property of the plated copper caused by Ralufon#14 in the electrolyte. By the addition of Ralufon#14 the crystalline orientation, grain size, and electrical resistivity changed significantly. In addition, compared to the thin films plated with pure electrolyte, the films prepared with Ralufon#14 exhibited considerable increase of the optical reflectance. The changes in crystalline orientation, grain size, and optical reflectance do not show noticeable variation when we increase the concentration of Ralufon#14 in the electrolytes.

Guideline Adherence to Colonoscopic Surveillance Intervals after Polypectomy in Korea: Results from a Nationwide Survey

( Seri Hong ),( Mina Suh ),( Kui Son Choi ),( Boyoung Park ),( Jae Myung Cha ),( Hyun-soo Kim ),( Jae Kwan Jun ),( Dong Soo Han ) 대한간학회 2018 Gut and Liver Vol.12 No.4

Background/Aims: People around the world are increasingly choosing to undergo colorectal cancer screening via colonoscopy. As a result, guideline adherence to postpolypectomy colonoscopy surveillance has drawn increasing attention. The present study was performed to assess recognition and adherence to guidelines among primary care physicians and gastroenterologists and to identify characteristics associated with compliance. Methods: A nationwide sample of primary care physicians employed at cancer screening facilities and registered members of the Korean Society of Gastrointestinal Endoscopy were recruited. Participants were asked to complete a survey of six hypothetical clinical scenarios designed to assess their potential course of action in response to screening or follow-up colonoscopy results. Frequencies and odds ratios and 95% confidence intervals for guideline adherence were estimated. Results: The proportions of doctors recommending shortened colonoscopy surveillance intervals for low- and high-risk adenomas were greater than 90% among primary physicians and were much lower among gastroenterologists. Guideline adherence was relatively good among groups of doctors who were young, had a specialty in gastroenterology, worked at tertiary hospitals, and cared for an appropriate number of patients. Conclusions: The present study reveals a remaining discrepancy between practitioner recommendations and current guidelines for postpolypectomy surveillance. Several factors were shown to be related to guideline adherence, suggesting a need for appropriate control and continuing education or training programs among particular groups of practitioners. (Gut Liver 2018;12:426-432)