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Anti-inflammatory and anti-noceceptive action of the crude extracts of Costus specious on rodents
Md. Ashraful Alam,Nusrat Subhan,Md. Abdul Awal,Md. Shohidul Alam,Kazi Akramudaulla 경희대학교 융합한의과학연구소 2008 Oriental Pharmacy and Experimental Medicine Vol.8 No.3
The effect of alcoholic extracts of Costus specious (Family: Zingiberaceae) was evaluated in experimental models of pain and inflammation. Oral administration of 100, 200 and 300 mg/kg of C. specious extracts were used for the above study. Crude extracts of C. specious (300 mg/kg dose) showed maximum time needed for the response against thermal stimuli (7.242 ± 0.532 s) which is comparable to diclofenac sodium (8.471 ± 0.257 s) in the hot plate test. The MPH (Maximum Possible Analgesia) has been found to be 14.285 for 300 mg/kg dose of the crude extract while the MPH for diclofenac was 15.857 after 60 min of administration in the hot tail-flick method. The crude extract at 300 and 200 mg/kg doses showed significant reduction in acetic acid induced writhings in mice with a maximum effect of 59.661% reduction at 300 mg/kg dose which is comparable to standard diclofenac sodium (73.4%). Alcoholic extract of C. specious showed significant inhibition in serotonin and egg albumin induced hind paw oedema in rats at 100, 200 and 300 mg/kg of the crude extracts respectively (Serotonin induced edema 44.22; 53.75; 58.51%; egg albumin induced edema - 41.317; 53.892; 59.880% inhibition after 4 h respectively). The antiinflammatory effects showed by the extract were comparable to that of standard indomethacin 5 mg/kg (Serotonin induced edema 77.56%; egg albumin induced edema 77.844% inhibition after 4 h). These results suggest that the extract possesses both the anti-inflammatory and analgesic activity on mice and rat model. The effect of alcoholic extracts of Costus specious (Family: Zingiberaceae) was evaluated in experimental models of pain and inflammation. Oral administration of 100, 200 and 300 mg/kg of C. specious extracts were used for the above study. Crude extracts of C. specious (300 mg/kg dose) showed maximum time needed for the response against thermal stimuli (7.242 ± 0.532 s) which is comparable to diclofenac sodium (8.471 ± 0.257 s) in the hot plate test. The MPH (Maximum Possible Analgesia) has been found to be 14.285 for 300 mg/kg dose of the crude extract while the MPH for diclofenac was 15.857 after 60 min of administration in the hot tail-flick method. The crude extract at 300 and 200 mg/kg doses showed significant reduction in acetic acid induced writhings in mice with a maximum effect of 59.661% reduction at 300 mg/kg dose which is comparable to standard diclofenac sodium (73.4%). Alcoholic extract of C. specious showed significant inhibition in serotonin and egg albumin induced hind paw oedema in rats at 100, 200 and 300 mg/kg of the crude extracts respectively (Serotonin induced edema 44.22; 53.75; 58.51%; egg albumin induced edema - 41.317; 53.892; 59.880% inhibition after 4 h respectively). The antiinflammatory effects showed by the extract were comparable to that of standard indomethacin 5 mg/kg (Serotonin induced edema 77.56%; egg albumin induced edema 77.844% inhibition after 4 h). These results suggest that the extract possesses both the anti-inflammatory and analgesic activity on mice and rat model.
Alam, Md Ashraful,Ki-Chul Kwon,Yan-Ling Piao,Young-Seok Kim,Nam Kim IEEE 2015 IEEE photonics journal Vol.7 No.1
<P>We propose and demonstrate a viewing-angle-enhanced integral imaging display (VAEIID) system that uses a time-multiplexed, two-directional sequential projection (TTSP) scheme and a directional elemental image generation and resizing (DEIGR) algorithm. The main idea behind the method is sharing the same image screen to display two-directional elemental image (DEI) sets with a time-multiplexed sequential projection scheme. The proposed system consists of three processes: acquisition of depth and color information of a real object using the Microsoft Kinect sensor, generation of two DEI sets considering two different angular perspectives using a DEIGR algorithm, and projection of two sets of DEIs using the TTSP scheme. Due to the two-directional projections, each elemental lens of the lens array collects two-directional illuminations from the two sets of elemental images (EIs) projected in a time-multiplexed sequential manner by using the TTSP scheme; this produces two point light sources (PLSs) at different positions on the focal plane of the lens array. The positions of the PLSs are predefined and are determined in terms of projection angle. In this case, the viewing angle comprises the combination of two diverging ray bundles emerging from the two DEI sets projected from two angular directions. As a result, the viewing angle of the proposed VAEIID system is enhanced by almost twice that of the conventional method.</P>
( Md Sufi Ullah Siddik Bhuyan ),( Eun Hei Lee ),( Abul Hasnat Md Ashraful Alam ),( Soa Choi ),( Ruri Lee ),( Kwanghyeon Song ),( Yong Chan Seo ) 한국폐기물자원순환학회(구 한국폐기물학회) 2015 한국폐기물자원순환학회 추계학술발표논문집 Vol.2015 No.-
Subcritical hydrolysis followed by methyl estrification was used to produce bio-diesel from low valued waste cooking oil at mild reaction conditions in this study. More than 90% fatty acid methyl esther (FAME) conversion was achieved by subcritical hydrolysis without using catalysts at 275℃ for 45 minutes. The highest conversion to linoleic acid (C18:2) was obtained at this condition. The higher content of free fatty acid (FFA) in waste cooking oil resulted in higher conversion to FAME. It was also observed more prominent at high temperature due to auto catalytic behavior of FFA. FAME yield found about 92% without using catalyst; whereas 98% yield was obtained using 80% TiO<sub>2</sub> loading S-TiO<sub>2</sub>/MCM-41 catalyst at 220℃ and 20 minutes. The amount of FAME increased may be due to trans-esterification of un-reacted TG, DG, and MG with methanol remained during the hydrolysis stage. The higher FAME conversion means the better quality bio-diesel.
Md Sufi Ullah Siddik Bhuyan,Eun Hei Lee,Abul Hasnat MD Ashraful Alam,Soa Choi,Ruri Lee,Kwanghyeon Song,Yong Chan Seo 한국폐기물자원순환학회 2015 한국폐기물자원순환학회 학술대회 Vol.2015 No.11
Subcritical hydrolysis followed by methyl estrification was used to produce bio-diesel from low valued waste cooking oil at mild reaction conditions in this study. More than 90% fatty acid methyl esther (FAME) conversion was achieved by subcritical hydrolysis without using catalysts at 275℃ for 45 minutes. The highest conversion to linoleic acid (C18:2) was obtained at this condition. The higher content of free fatty acid (FFA) in waste cooking oil resulted in higher conversion to FAME. It was also observed more prominent at high temperature due to auto catalytic behavior of FFA. FAME yield found about 92% without using catalyst; whereas 98% yield was obtained using 80% TiO2 loading S-TiO2/MCM-41 catalyst at 220℃ and 20 minutes. The amount of FAME increased may be due to trans-esterification of un-reacted TG, DG, and MG with methanol remained during the hydrolysis stage. The higher FAME conversion means the better quality bio-diesel.
( Md Sufi Ullah Siddik Bhuyan ),( Eun Hei Lee ),( Abul Hasnat Md Ashraful Alam ),( Soa Choi ),( Ruri Lee ),( Kwanghyeon Song ),( Yong Chan Seo ) 한국폐기물자원순환학회(구 한국폐기물학회) 2015 한국폐기물자원순환학회 심포지움 Vol.2015 No.2
Subcritical hydrolysis followed by methyl estrification was used to produce bio-diesel from low valued waste cooking oil at mild reaction conditions in this study. More than 90% fatty acid methyl esther (FAME) conversion was achieved by subcritical hydrolysis without using catalysts at 275℃ for 45 minutes. The highest conversion to linoleic acid (C18:2) was obtained at this condition. The higher content of free fatty acid (FFA) in waste cooking oil resulted in higher conversion to FAME. It was also observed more prominent at high temperature due to auto catalytic behavior of FFA. FAME yield found about 92% without using catalyst; whereas 98% yield was obtained using 80% TiO2 loading S-TiO<sub>2</sub>/MCM-41 catalyst at 220℃ and 20 minutes. The amount of FAME increased may be due to trans-esterification of un-reacted TG, DG, and MG with methanol remained during the hydrolysis stage. The higher FAME conversion means the better quality bio-diesel.
Nusrat Subhan,Md Mokarram Hossain,Raushanara Akter,Muntasir Mamun Majumder,Md Mostafizur Rahman,Kamaluddin Ahmed,Abdul Ghani,Md Ashraful Alam,SM Raquibul Hasan 경희대학교 융합한의과학연구소 2009 Oriental Pharmacy and Experimental Medicine Vol.9 No.4
The effect of alcoholic extract of Anthocephalus (A.) Cadamba Roxb. was evaluated in experimental models of pain and ulcer. Hot tail flick test, hot plate test and acetic acid induced writhing test were employed for evaluating the peripheral as well as central analgesic mechanism exerted by the extracts. Gastroprotective activity was examined by HCl and ethanol induced gastric damage test. Test group received crude extract 500 mg/kg showed maximum time needed for the response against thermal stimuli (6.26 ± 0.439 s) which is comparable to diclofenac sodium (6.56 ± 0.381 s) in hot tail flick method. These experimental results also followed the experimental results of hot plate test where crude extract 500 mg/kg showed maximum time needed for the response against thermal stimuli (4.74 ± 0.234 s) which is comparable to diclofenac sodium (5.58 ± 0.585 s). The crude extract at 500 and 250 mg/kg showed significant reduction in acetic acid induced writhing in mice with a maximum effect of 68.026% reduction at 500 mg/kg dose which is comparable to standard diclofenac sodium (79.93%). In gastroprotective study the extract of A. Cadamba (250 and 500 mg/kg) significantly inhibited ulceration induced by both HCl and ethanol dose dependently. Results of the study suggest that the extract possesses both analgesic and gastroprotective activity on mice. The effect of alcoholic extract of Anthocephalus (A.) Cadamba Roxb. was evaluated in experimental models of pain and ulcer. Hot tail flick test, hot plate test and acetic acid induced writhing test were employed for evaluating the peripheral as well as central analgesic mechanism exerted by the extracts. Gastroprotective activity was examined by HCl and ethanol induced gastric damage test. Test group received crude extract 500 mg/kg showed maximum time needed for the response against thermal stimuli (6.26 ± 0.439 s) which is comparable to diclofenac sodium (6.56 ± 0.381 s) in hot tail flick method. These experimental results also followed the experimental results of hot plate test where crude extract 500 mg/kg showed maximum time needed for the response against thermal stimuli (4.74 ± 0.234 s) which is comparable to diclofenac sodium (5.58 ± 0.585 s). The crude extract at 500 and 250 mg/kg showed significant reduction in acetic acid induced writhing in mice with a maximum effect of 68.026% reduction at 500 mg/kg dose which is comparable to standard diclofenac sodium (79.93%). In gastroprotective study the extract of A. Cadamba (250 and 500 mg/kg) significantly inhibited ulceration induced by both HCl and ethanol dose dependently. Results of the study suggest that the extract possesses both analgesic and gastroprotective activity on mice.
Development of jute rope hybrid composite plate using carbon fibre
Karim Nouri,Md. Ashraful Alam,Mohammad Mohammadhassani,Mohd Zamin Bin Jumaat,Amir Hosein Abna 국제구조공학회 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.56 No.6
Jute rope is one of the most popular materials used for composites in various industries and in civil engineering. This experimental study investigated two types of jute rope with different diameters for jute rope composite plates to determine the best combination of jute rope and carbon fiber in terms of ratio and physical and mechanical properties. Eight combinations of carbon fiber and jute rope with different percentages of carbon fiber were analyzed. Tensile tests for the jute rope composite plate and hybrid jute rope composite were conducted, and the mechanical and physical properties of the specimens were compared. Thereafter, the ideal combinations of jute rope with an optimum percentage of carbon fiber were identified and recommended. These particular combinations had tensile strengths that were 2.23 times and 1.76 times higher than other varieties in each type.