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      • Time-moving Metaphors and Ego-moving Metaphors: Which Is Better Comprehended by Taiwanese?

        ( Hsin Mei Huang May ),( Ching Yu Hsieh Shelley ) 한국언어정보학회 2007 학술대회 논문집 Vol.2007 No.-

        This is a semantic pilot study which concentrates on how people in Taiwan process the temporal metaphors, ego-moving metaphor and time-moving metaphor. Motivated by the research of Gentner, Imai, and Boroditsky (2002) in which the English native speakers comprehend ego-moving metaphors faster than time-moving metaphors, the present study attempts to reexamine whether the faster reaction to ego-moving metaphors is shared by both the Chinese native speakers and EFL learners. To achieve the goals, 25 Chinese/English bilinguals are invited to be examined via the16 Chinese and 16 English test sentences. The recordings of their accuracy on each item are served as the databases used to compare with the study of Gentner, Imai, and Boroditsky (2002). The two finding presented here are: (1) when the subjects tested in their native language, Chinese, they process ego-moving metaphors better. (2) when tested in the foreign language, English, they conceptualize time-moving metaphors much better.

      • Optimal Positions Selection for Watermark Inclusion based on a Nature Inspired Algorithm

        Jumana Waleed,Huang Dong Jun,Saad Hameed,May Kamil 보안공학연구지원센터(IJSIP) 2015 International Journal of Signal Processing, Image Vol.8 No.1

        One of the powerful optimization tools that has been exploited in the computer world are nature inspired algorithms (NIAs), they are also used to solve problems in the computer programming world. For many years new algorithms have been developed regarding computer science and engineering communities such algorithms concentrates on NIAs which has proven their capabilities in many aspect, in some situation rapid solutions are needed to solve some problems these algorithms provides a versatile robust solutions for many of these situations. This paper presents a watermark inclusion based on a recently presented nature inspired algorithm to enhance the digital image watermarking procedure to be used for copyright protection. The nature inspired algorithm in focus is used to perfectly identify optimal positions in the discrete wavelet transform domain (DWT) for watermark inclusion in the gray scale image, The obtained results are shown in the experimental results section clarifying the superiority of using the algorithm in focus for the watermarking technique, In addition, showing how the algorithm optimum positions are obtained with lowest effect to the PSNR value of the produced watermark included images.

      • PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.

        Vives-Bauza, Cristofol,Zhou, Chun,Huang, Yong,Cui, Mei,de Vries, Rosa L A,Kim, Jiho,May, Jessica,Tocilescu, Maja Aleksandra,Liu, Wencheng,Ko, Han Seok,Magran?, Jordi,Moore, Darren J,Dawson, Valina L,G National Academy of Sciences 2010 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.107 No.1

        <P>Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1) and PARK2/Parkin mutations cause autosomal recessive forms of Parkinson's disease. Upon a loss of mitochondrial membrane potential (DeltaPsi(m)) in human cells, cytosolic Parkin has been reported to be recruited to mitochondria, which is followed by a stimulation of mitochondrial autophagy. Here, we show that the relocation of Parkin to mitochondria induced by a collapse of DeltaPsi(m) relies on PINK1 expression and that overexpression of WT but not of mutated PINK1 causes Parkin translocation to mitochondria, even in cells with normal DeltaPsi(m). We also show that once at the mitochondria, Parkin is in close proximity to PINK1, but we find no evidence that Parkin catalyzes PINK1 ubiquitination or that PINK1 phosphorylates Parkin. However, co-overexpression of Parkin and PINK1 collapses the normal tubular mitochondrial network into mitochondrial aggregates and/or large perinuclear clusters, many of which are surrounded by autophagic vacuoles. Our results suggest that Parkin, together with PINK1, modulates mitochondrial trafficking, especially to the perinuclear region, a subcellular area associated with autophagy. Thus by impairing this process, mutations in either Parkin or PINK1 may alter mitochondrial turnover which, in turn, may cause the accumulation of defective mitochondria and, ultimately, neurodegeneration in Parkinson's disease.</P>

      • KCI등재후보

        1980년대 이후 대만 음식(cuisine)의 형성

        마이클 사오(Hsin-Huang Michael Hsiao),메이창(May Yu-Hsin Chang),메이-후이첸(Mei-Hui Chen),권정화(번역자) 서울대학교 아시아연구소 2015 아시아리뷰 Vol.5 No.1

        대만 음식의 출현은 대만의 민주화 과정과 1980년대 이래 국가 정체성의 성장과 관련이 깊다. 어떠한 측면에서 대만 음식의 형성은 중국 본토의 장저(江浙) 음식, 쓰촨(四川) 음식, 광둥(廣東) 음식 체계가 우세한 가운데 대만 내 두 개의 주요 민족음식, 즉 민난과 학카 음식이 자유화된 것으로 볼 수도 있다. 한족의 음식으로 알려진 민난과 학카 음식이 대만을 대표하는 요리로 급부상하게 된 것이다. 그러나 한족이 아닌 원주민 음식은 여전히 대만 음식으로 통합되지 않고 있는 점 또한 주목해야 한다. 이 글은 대만 음식의 부상이 정치적 변환과 문화적 변화를 뛰어넘는 사회적 산물이라는 점에 주목하고 있다. 민난과 학카 민족 음식의 소비는 가정의 범주를 넘어 레스토랑에서 볼 수 있는 상품화된 ‘요리’로서 빠르게 자리잡고 있다. 이 글은 민난과 학카 민족 음식의 ‘요리화’와 ‘대중화’의 특징과 변화를 설명하고자 한다. 또한 민난, 학카 음식이 어떻게 ‘표현’되고, 어떠한 ‘위치’에 있고, 대만 국가 음식으로써 ‘어느 정도’ 역할을 하는지도 주목한다. 결론에서는 민주주의, 민족성, 국가정체성이 어떻게 연관되어 있고, 이들의 관계가 대만의 현대 음식에 어떻게 반영되어 있는지를 살펴본다. The emergence of Taiwanese cuisine has much to do with the democratization process and the growth of Taiwan national identity since the 1980s. In one way, the making of Taiwanese cuisine can be seen as the liberalization of two major ethnic foods, Mainan and Hakka, from the dominance of Mainland China’s provincial food customs such as that of Jiang-Zhe, Szechuan, and Guandong. The two ethnic Han food of Minnan and Hakka have thus been ungraded to constitute the new core components of the rising Taiwan’s national cuisine. It is equally important to note that, however, the non-Han aborigine food has not been considered as an integral part of Taiwanese cuisine. This paper intends to argue that the rise of Taiwanese cuisine is the direct social product of the above political transformation and cultural change. The Minnan and Hakka ethnic foods have since then been rapidly commercialized to become the recognized “cuisine” popularly served in restaurants beyond household consumption. The rise of “cuisinization” as well as “popularization” of ethnic Mainnan and Hakka foods will then be discussed in this paper by identifying the main features and changes of each of the ethnic food. Special attention is also paid to how Minnan and Hakka food are being “presented,” “positioned” and “weighted” in the constitution of “Taiwanese national cuisine.”Finally, in the conclusion, the interplay of democracy, ethnicity and national identity and its impact on Taiwan’s contemporary foodscape will be highlighted.

      • The Major Changes of Gilbert’s Syndrome and UGT1A1 Gene Abnormalities in Mongolians Are Western Type

        ( Nyam Biziya ),( Nyamaa Bayarmaa ),( Jui-ting Hu ),( May-jen Huang ),( Ching-shan Huang ),( Sien-sing Yang ) 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1

        Aims: Hereditary abnormalities of uridinediphosphoglucuronate-glucuronosyltransferase 1A1 (UGT1A1) gene is the major cause of unconjugated hyper-bilirubinemia. The abnormalities of UGT1A1 gene in Mongolian population remain uninvestigated. Eight in 99 consecutive Mongolian adults developed indirect hyperbilirubinemia. We therefore studied Mongolian patients for GS and UGT1A1 abnormalities. Methods: Between 2007 and 2014, ninety-nine consecutive Mongolian adult patients of chronic liver disease from the Department of Gastroenterology, Mongolian National University of Medical Sciences were studied. Eight (8.1%) of them developed indirect hyperbilirubinemia. All patients were tests for blood chemistries, hemoglobin, international normalized ratio (INR), mean corpuscular volume (MCV), glucose-6-phosphate dehydrogenase (G6PD) levels as well as UGT1A1 genetic abnormalities. We genotyped the UGT1A1 gene for the A(TA)6TAA (6) or A(TA)7TAA (7) promoter variant, and the coding region for nucleotide mutations (nt)-211 G to A, nt-686 C to A, nt-1091 C to T and nt-1456 T to G. Results: Among the eight patients that developed indirect hyperbilirubinemia, six were male and two were female. All patients had hemoglobin, INR, MCV and G6PD levels within normal limit and we excluded possibility of anemia, decompensated liver function, thalassemia and G6PD deficiency. Our data confirms two variants of the UGT1A1 gene among the Mongolian patients. Two case were homozygous for nt-211G>A mutation, two case heterozygous for 6/7 promoter variants and nt-211G>A mutation, whereas four case were typical GS with homozygous 7/7 promoter genotype with no mutation in the coding region None of our Mongolian patients had mutations at nt-686, nt-1091 or nt-1456. Conclusions: Our pilot results show that GS and UGT1A1 abnormalities are common in Mongolians. Prevalence of the UGT1A1 promoter abnormalities in Mongolians are similar to the Western population; whereas the high prevalence of nt-211G>A variant is similar to the Asians. Further studies with much larger number of patients are necessary to confirm the genetic status of GS and UGT1A1 variants in Mongolians.

      • Assessing the Range of Validity of Current Tube Models through Analysis of a Comprehensive Set of Star-Linear 1,4-Polybutadiene Polymer Blends

        Hall, Ryan,Desai, Priyanka S.,Kang, Beom-Goo,Huang, Qifan,Lee, Sanghoon,Chang, Taihyun,Venerus, David C.,Mays, Jimmy,Ntetsikas, Konstantinos,Polymeropoulos, George,Hadjichristidis, Nikos,Larson, Ronal American Chemical Society 2019 Macromolecules Vol.52 No.20

        <P>We blend newly synthesized nearly monodisperse four-arm star 1,4-polybutadienes with various well-entangled linear polymers, confirming the conclusions in Desai et al. [<I>Macromolecules</I>201649 (13)49644977] that advanced tube models, namely, the hierarchical 3.0 and branch-on-branch models [Wang, Z.; <I>J. Rheol.</I>201054 (2)223260], fail to predict the linear rheological data when the pure linear polymers have shorter relaxation times, but within 3-4 orders of magnitude of the star polymer. However, when the linear polymer has a longer relaxation time than the star, our new work, surprisingly, finds that non-monotonic dependence of terminal relaxation behavior on composition is both observed experimentally and captured by the models. Combined with previous data from the literature, we present results from over 50 1,4-polybutadiene star-linear blends, suitable for thorough testing of rheological models of entangled polymers.</P> [FIG OMISSION]</BR>

      • Challenging Tube and Slip-Link Models: Predicting the Linear Rheology of Blends of Well-Characterized Star and Linear 1,4-Polybutadienes

        Desai, Priyanka S.,Kang, Beom-Goo,Katzarova, Maria,Hall, Ryan,Huang, Qifan,Lee, Sanghoon,Shivokhin, Maksim,Chang, Taihyun,Venerus, David C.,Mays, Jimmy,Schieber, Jay D.,Larson, Ronald G. American Chemical Society 2016 Macromolecules Vol.49 No.13

        <P>We compare predictions of two of the most advanced versions of the tube model, namely the 'Hierarchical model' by Wang et al. [J. Rheol. 2010, 54, 223] and the BoB (branch-on-branch) model by Das et al. [J. Rheol. 2006, SO, 207], against linear viscoelastic G' and G '' data of binary blends of nearly monodisperse 1,4-polybutadiene 4-arm star polymer of arm molar mass 24 000 g/mol with a monodisperse linear 1,4-polybutadiene of molar mass 58 000 g/mol. The star was carefully synthesized and characterized by temperature gradient interaction chromatography and by linear rheology over a wide frequency region through time temperature superposition. We found large failures of both the Hierarchical and BoB models to predict the terminal relaxation behavior of the star/linear blends, despite their success in predicting the rheology of the pure star and pure linear polymers. This failure occurred regardless of the choices made concerning constraint release, such as assuming arm retraction in 'fat' or 'skinny' tubes. Allowing for 'disentanglement relaxation' to cut off the constraint release Rouse process at long times does lead to improved predictions for our blends, but leads to much worse predictions for other star/linear blends described in the literature, especially those of Shivokhin et al. [Macromolecules 2014, 47, 2451]. In addition, our blends and those of Shivokhin et al. were also tested against a coarse-grained slip-link model, the 'clustered fixed slip-link model (CFSM)' of Schieber and co-workers [J. Rheol. 2014, 58, 723], in which several Kuhn steps are clustered together for computational efficiency. The CFSM with only two molecular-weight- and chain-architecture-independent parameters was able to give very good agreement with all experimental data for both of these sets of blends. In light of its success, the CFSM slip-link model may be used to address the constraint release issue more rigorously and potentially help develop improved tube models.</P>

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