Analysis of Gene Expression Responses to a Salmonella Infection in Rugao Chicken Intestine Using GeneChips

Luan, D.Q.,Chang, G.B.,Sheng, Z.W.,Zhang, Y.,Zhou, W.,Li, Z.Z.,Liu, Y.,Chen, G.H. Asian Australasian Association of Animal Productio 2012 Animal Bioscience Vol.25 No.2

Poultry products are an important source of Salmonella enterica. An effective way to reduce food poisoning due to Salmonella would be to breed chickens more resistant to infection. Unfortunately host responses to Salmonella are complex with many factors involved. To learn more about responses to Salmonella in young chickens of 2 wk old, a cDNA Microarray containing 13,319 probes was performed to compare gene expression profiles between two chicken groups under control and Salmonella infected conditions. Newly hatched chickens were orally infected with S. enterica serovar Enteritidis. Since the intestine is one of the important barriers the bacteria encounter after oral inoculation, intestine gene expression was investigated at 2 wk old. There were 588 differentially expressed genes detected, of which 276 were known genes, and of the total number 266 were up-regulated and 322 were down-regulated. Differences in gene expression between the two chicken groups were found in control as well as Salmonella infected conditions indicating a difference in the intestine development between the two chicken groups which might be linked to the difference in Salmonella susceptibility. The differential expressions of 4 genes were confirmed by quantitative real-time PCR and the results indicated that the expression changes of these genes were generally consistent with the results of GeneChips. The findings in this study have lead to the identification of novel genes and possible cellular pathways, which are host dependent.

Polyurethane sponges decorated with reduced graphene oxide and silver nanowires for highly stretchable gas sensors

Luan, Yange,Zhang, Shaolin,Nguyen, Thuy Hang,Yang, Woochul,Noh, Jin-Seo Elsevier 2018 Sensors and actuators. B Chemical Vol.265 No.-

<P><B>Abstract</B></P> <P>Unlike the stretchable physical sensors such as stretchable pressure sensors, strain sensors, and temperature sensors, few works have been reported on the stretchable gas sensors. This study presents that stretchable gas sensors can be fabricated by decorating reduced graphene oxide/silver nanowires (rGO/AgNWs) hybrids on the porous polyurethane (PU) sponges using a facile dip-coating method. The sensors show good room-temperature responses to NO<SUB>2</SUB> gas under both a bending strain (r = 3 mm) and a large tensile strain up to 60%. The response of about −15% is measured at a 50 ppm of NO<SUB>2</SUB> under a 60% strain. Furthermore, reducing gases like acetone and ethanol can also be detected under the large strains. The results of this study offer a new insight into realization of highly stretchable and easy-to-fabricate gas sensors.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Highly stretchable gas sensors are fabricated by the dip-coating method. </LI> <LI> The electrical properties of the sensors can be easily tuned. </LI> <LI> The sensors can detect an oxidizing gas, NO<SUB>2</SUB>, and reducing gases, acetone and ethanol. </LI> <LI> The stretchable gas sensors work stably even under large strains up to 60%. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Enzymatic Synthesis of Tetracyclines Glycosides

Luan Luong Chu,Ramesh Prasad Pandey,Jae Kyung Sohng 한국당과학회 2015 한국당과학회 학술대회 Vol.2015 No.02

Mussel-inspired dopamine-mediated graphene hybrid with silver nanoparticles for high performance electrochemical energy storage electrodes

Luan, Van Hoang,Bae, Daeryeong,Han, Jong Hun,Lee, Wonoh Elsevier 2018 Composites Part B, Engineering Vol.134 No.-

<P><B>Abstract</B></P> <P>To facilitate the immobilization of the silver nanoparticles with high crystallinity and stability, the mussel-inspired dopamine is functionalized on the surface of the graphene. Considering the unique adhesive property of a catechol group in the dopamine toward metallic ions, a large amount of silver nanoparticles can be coated on the surface of the dopamine-functionalized graphene. To use the high surface area of graphene, large-sized graphene sheets are prepared using the microwave heat treatment of graphite powder followed by chemical oxidation and exfoliation. In addition, the large-area graphene sheets are selectively collected by a pH-assisted fractionation technique and are confirmed by the green-light filtered optical microscopic images. The dopamine-mediated graphene hybrid with silver nanoparticles shows superior electrochemical activity with enhanced electrical conductivity by promoting the decoration of stable silver nanoparticles on the surface of graphene. The resulting hybrid exhibits 7.6 times and 1.6 times higher electrochemical capacitance than that of the bare and graphene/silver hybrid-modified glassy carbon electrodes, respectively.</P>

Highly porous and capacitive copper oxide nanowire/graphene hybrid carbon nanostructure for high-performance supercapacitor electrodes

Luan, Van Hoang,Han, Jong Hun,Kang, Hyun Wook,Lee, Wonoh Elsevier Science Ltd 2019 Composites Part B, Engineering Vol.178 No.-

<P><B>Abstract</B></P> <P>Three-dimensionally porous carbon nanostructures have been widely used in energy storage applications owing to their large specific surface areas and excellent electrical properties. In addition, copper oxide has been considered as an effective pseudocapacitive material to significantly increase the energy density. In this paper, we introduce the synergetic combination of one-dimensional copper oxide nanowires and two-dimensional graphene sheets to fabricate a highly porous and electrically conductive three-dimensional hybrid nanostructure for high-performance supercapacitor electrodes with increased capacitances. The copper oxide nanowires were synthesized by reduction of copper nitrate and sequential oxidation at a high temperature. The copper oxide nanowire/graphene hybrid three-dimensional nanostructure was obtained by a self-assembly technique through a simple hydrothermal treatment. The hybrid nanostructure had an acceptable surface area and increased thermal stability. The porous hybrid nanostructure utilized as a supercapacitor electrode provided 1.6 times higher electrochemical capacitance than that of a graphene-only nanostructure-based electrode as well as superior capacitance stability with a retention of 91.2% retention after 5,000 charge−discharge cycles. Owing to the increased capacitance, the manufactured electrode exhibited high a specific energy density of 50.6 Wh kg<SUP>−1</SUP> at a power density of 200 W kg<SUP>−1</SUP>, which demonstrates its potential for use in electrochemical energy storage devices.</P>

Applications of Swarm Intelligence for Multi-Access Edge Computing Systems: A Brief Overview

Luan N.T. Huynh,Md Delowar Hossain,Md Imtiaz Hossain,Tri D.T. Nguyen,Phoo Pyae Sone,Yunkon Kim,Eui-Nam Huh 한국정보과학회 2020 한국정보과학회 학술발표논문집 Vol.2020 No.7

Efficient Single Vessel Multi-enzymatic Glycosylation for Bioconversion of Tetracyclines Antibiotics to Novel Glucoside Derivatives

Luan Luong Chu,Ramesh Prasad Pandey,Tae-Su Kim,Van Thuy Thi Pham,Jae Kyung Sohng 한국당과학회 2018 한국당과학회 학술대회 Vol.2018 No.01

Single vessel multi-enzyme UDP-α-D-glucose recycling system was coupled with a forward glucosylation reaction to produce glucose moiety conjugated novel derivatives of different tetracycline antibiotic analogues. Among five tetracycline analogues used for the reaction, four molecules (chlorotetracycline, doxytetracycline, meclotetracycline, and minotetracycline) were accepted by a glycosyltransferase enzyme, YjiC, from Bacillus licheniformis to produce glucoside derivatives. However, the enzyme was unable to conjugate sugar unit to rolitetracycline. All glucosides of tetracycline derivatives were characterized by ultraviolet absorbance maxima, ultra-pressure liquid chromatography coupled with photo-diode-array, and high-resolution quadruple time-of-flight electrospray mass spectrometry analyses. These synthesized glucosides are novel tetracycline derivatives. The conversion of tetracycline analogues to respective glucosides has been found to be very low yet. This gives the clue that the enzyme has low preferences toward tetracycline molecules. Attachment of bulky group in rolitetracycline might have prevented the molecule to reach the catalytic cleft of GT enzyme. Results of this research could become a basis to explore the possibility of synthesizing glucosylated derivatives of different tetracyclines using GT enzyme.

Energy Efficiency Assessment in Plunge-Face Grinding of Cemented Tungsten Carbide Cutting Inserts

Luan Carreira,Amauri Hassui,Carlos Ventura 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.10 No.6

Due to the high demand for electricity in the manufacturing industry and the efforts to reduce environmental impact, investigations to increase energy efficiency in machining processes have been increasingly carried out. However, information on the behavior of insert grinding process is rarely found. Within this context, this work presents results related to the influence of grinding parameters and abrasive tool characteristics on the energy efficiency during plunge-face grinding of cemented tungsten carbide cutting inserts. For this, grinding forces and consumed electrical energy were measured during the process and sustainability indexes to analyze the relation between insert quality (surface and edge roughness) and consumed energy were calculated in different process conditions. As a result, it was observed that grinding parameters had little influence on insert quality, but an increase in the axial feed speed reduced the consumed energy in approximately 60%, leading to sustainability indexes next to one, i.e., to a greater equilibrium between energy consumption and quality properties.

Strain rate sensitivity in commercial pure titanium: The competition between slip and deformation twinning

Luan, Qinmeng,Britton, T. Benjamin,Jun, Tea-Sung Elsevier 2018 Materials science & engineering. properties, micro Vol.734 No.-

<P><B>Abstract</B></P> <P>Titanium alloys are widely used in light weight applications such as jet engine fans, where their mechanical performance under a range of loading regimes is important. Titanium alloys are mechanically anisotropic with respect to crystallographic orientation, and remarkably titanium creeps at room temperature. This means that the strain rate sensitivity (SRS) and stress relaxation performance are critical in predicting component life. In this work, we focus on systematically exploring the macroscopic SRS of Grade 1 commercially pure titanium (CP Ti) with varying grain sizes and texture using uniaxial compression. Briefly, we find that Ti samples had positive SRS and samples compressed along the sheet rolling direction (RD) (i.e. soft grains dominant) were less rate sensitive than bars compressed along the sheet normal direction (ND) (i.e. hard grains dominant). We attribute this rate sensitivity to the relative activity of slip and twinning. Within the grain size range of ~ 317 ± 7 μ m , we observe an increase in the rate sensitivity, where volume fraction of { 10 1 ̅ 2 } < 10 1 ̅ 1 > T1 tensile twins was low, and the twin width at different strain rates were similar. These observations imply that the macroscopic rate sensitivity is controlled by the ensemble behaviour of local deformation processes: the amount of slips accumulated at grain boundaries affects the SRS, which is grain size and texture dependent. We hope that this experimental study motivates mechanistic modelling studies using crystal plasticity, including strain rate sensitivity and twinning, to predict the performance of titanium alloys.</P>

Identifying New Technologies in Product and Processes through Patent Databanks

Luan Carlos Santos Silva,Carla Schwengber ten Caten,Silvia Gaia,Renata Tilemann Facó,Lidiana Zocche,Rosana Travessini 한국유통과학회 2015 The Journal of Industrial Distribution & Business( Vol.6 No.3

Purpose - This paper’s aim is to analyze the technological information in patent databanks as a strategy in prospecting for new technologies. Research design, data, and methodology - We detail the major free electronic database sources for patent information, the patent documents, the patent document structures, INID codes (Internationally Agreed Numbers for the Identification of Data), indexation, references, and classification notions. Additionally, we review and analyze information on the activities of the Center of Dissemination Documentation and Technological Information (CEDIN) from the National Institute of Intellectual Property (INPI) of Brazil for the period 2000 to 2011. Results - The research shows that the technological information contained in the patents could provide a wide range of functionality within companies and universities. Conclusions - In recent years, (CEDIN), a specialist in intellectual property, has been serving internal and external users by providing guidance on the basis of patents and other literature, but the number of users served is still small. In order to familiarize more potential users of such technological information, task forces should be created among INPI, universities, and companies.