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Hwakyung Hwang,Yiseul Noh,Jinyoung Kim,Yeonsun Jeon,Soyeon Park,Pureum Noh,Bitna Lee,Injung Kim,Soyeong Lim,Yikweon Jang,Gilsang Jeong 한국응용곤충학회 2013 한국응용곤충학회 학술대회논문집 Vol.2013 No.04
In Hymenoptera, thanks to its haplodiploid sex determination, arrhenotokous parasitoid females are able to control offspring sex ratio by determining whether to use sperm or not at the time of oviposition. However, the offspring sex ratio may also be influenced by the mating behavior of a male. When a male searches females, he will have more chances to encounter with other males in a high male density population than low male density population. If the male is competitive, the male can find females faster and may have longer copulation time, and eventually transfer more sperm than other males. In this study, we investigated mate searching time, copulation duration and offspring sex ratio as a function of the male density. Although the results show difference between searching time and copulation duration, they are not statistically significant. We will discuss the statistical consequence, male density dependent offspring sex ratio and its evolutionary implications.
The Phylogenetic Relationship in the Korean ant Species : Genus Myrmica
Pureum Noh,Rahayu Oktaviani,Taesung Kwon,Soyeon Park,Hwakyung Hwang,Bitna Lee,Injung Kim,Yeonsun Jeon,Soyeong Lim,Jae Chun Choe,Gilsang Jeong 한국응용곤충학회 2013 한국응용곤충학회 학술대회논문집 Vol.2013 No.04
In Korea, twelve species in genus Myrmica have been described. Some of them are morphologically similar and this makes their identification difficult. For this reason, we collected several Myrmica species in question and inferred their phylogenetic relationship using the 418bp partial COI (cytochrome C oxidase 1) region from a total of 33 individuals. We found that the CO1 haplotypes are effectively grouped into three clusters that match well to their external morphological characters. Although this three species could be distinguished by the only small part of the COI region, the two individual sample of the M. kotokuii and one sample of the M. carinata are included in the M. kurokii group. The results indicate that the morphological identification could be obscure in the three species and it requires a close examination for this phenomenon.
인공지능 기반 신생혈관성 나이관련황반변성 진단보조소프트웨어 사용자 인터페이스 개선 연구
구원미(Wonmi Gu),김소영(Soyoung Kim),김영은(Young Eun Kim),박성희(Sunghee Park),김문수(Moonsu Kim),임화경(Hwakyung Lim),허태영(Tae-Young Heo),김도윤(Doyun Kim),민정기(Jung Kee Min),홍석수(Seoksu Hong),윤재석(Jaesuk Yun) 대한약학회 2024 약학회지 Vol.68 No.2
With the recent development of Software as a Medical Device (SaMD), the significance of reducing use errors in medical devices is increasing. In this study, we conducted a formative evaluation of Artificial Intelligence (AI)-based software for ophthalmic image detection and diagnosis. The software automatically displays the presence or absence of neovascular age-related macular degeneration using fundus images to assist medical personnel in making diagnostic decisions. We aimed to find ways to reduce the number of use errors in formative evaluations. For this purpose, we conducted usability testing by performing tasks based on use scenarios for usability formative evaluations with intended users in their intended use environments, and then modified the user interface to reduce use errors. The initial formative evaluation revealed errors in utilizing the capture and dragand- drop functions for uploading fundus images, checking analysis results, and perform logout procedures. To reduce use errors, we improved the function by relocating the capture icon, displaying a hand-shaped cursor during dragging, inserting a fundus position guide, and eliminating the drag-and-drop function. We have also enhanced the design to present analytics results in a more intuitive manner and added a separate logout button to reduce the risk of use error. As a result, the number of use errors in the formative evaluation decreased from six to one in the summative evaluation. The development of ophthalmic image detection and diagnosis assistant software that reflects these improvements is expected to enhance user safety, usability, and reduce use errors.
인체세포ㆍ조직이용 의료제품 등의 규제에 관한 국내외 규정 비교 및 안전관리 개선방안 연구
이지훈(Jihoon Lee),최수경(Soo Kyung Choi),김주희(Juhui Gim),박미영(Miyoung Park),박수현(Soo Hyun Park),최진희(Jinhee Choi),임화경(Hwakyung Lim),노혜민(Hyemin Noh),이윤희(Yun hee Lee),윤재석(Jaesuk Yun) 대한약학회 2018 약학회지 Vol.62 No.3
Over the past several decades, human-derived cells, tissues, and cell- and tissue-based therapies have contributed to essential body function regeneration in the absence of effective alternative medicine substitute. This study reviewed strength and weakness of the regulation related to human-derived cells, tissues based pharmaceutical products compared to the US regulation, and suggested points for improvement classified into three categories. First, it is necessary to supplement regulations and guidelines on donor eligibility for pharmaceutical products. Second, there is a need to integrate regulations related to classify pharmaceutical product into biologics, device, and combination products. Finally, there is a need to develop and supplement the traceability of biological traces and the regulations for biological monitoring systems of pharmaceutical products. Collectively, it would be necessary to revise the regulations and the guidelines for the approval, manufacture, management and tracking of human cell/tissue derived pharmaceutical products by collecting opinions from researchers, industry, and clinical health care workers with a systematic long-term goal.