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      • KCI등재후보

        How to Write an Impactful Asian Case Study: Tips for Winning a Case Competition

        Li-Chen Lim,Narmin Tartila Banu Academy of Asian Business (AAB) 2018 Academy of Asian Business Review Vol.4 No.2

        The objective of this paper is to present the personal experiences of two advisors on how to compose a compelling business case for journals like Academy of Asian Business Review or World Asian Case Competition. The first section provide advices on creating and writing a business case, and followed by the concept and types of business case study. Next, few considerations that would help an author to compose a great case study, such as how to find an interesting topic, how to assess permission-availability to utilize its name and relevant information, and how to make sure the information gathered is consistent and stay on track.

      • KCI등재

        Bytedance: The Road to Success of a Global Influential Social Media Platforms Creator

        Li-Chen Lim,Lee Leong-Weng,Lee Weng Yen,Huang Jie,Jastina Puteri Simandjoentak Academy of Asian Business (AAB) 2019 Academy of Asian Business Review Vol.5 No.2

        Started an AI-powered news aggregation company in 2012, Bytedance has developed into a global technology enterprise with a valuation of over $75 billion dollar in less than 10 years. This case study analyzes Bytedance’s remarkable success that is rarely achieved by China’s tech giants. The great success of Bytedance can be attributed to its dedication of the founder, people and continuous innovation of the short video app, TikTok. Despite TikTok has reached global popularity, this short video app is criticized for causing smartphone addiction due to its content stickiness. At the same time, stiff competition from local competitors is forcing Bytedance to expand into other markets. The global expansion of Bytedance via the usage of the TikTok app did not go well after TikTok was criticized for spreading offensive content and fake news. Eventually, Bytedance has to address these prevailing challenges

      • SCISCIESCOPUS

        Peripheral arterial disease is associated with coronary artery spasm as assessed by an intracoronary acetylcholine provocation test

        Chen, Kang-Yin,Rha, Seung-Woon,Li, Yong-Jian,Poddar, Kanhaiya L,Jin, Zhe,Minami, Yoshiyasu,Wang, Lin,Li, Guang-Ping,Saito, Shigeru,Park, Jae-Hyoung,Na, Jin-Oh,Choi, Cheol Ung,Lim, Hong-Euy,Kim, Jin-Wo Blackwell Publishing Ltd 2009 Clinical and Experimental Pharmacology & Physiolog Vol.36 No.11

        <P>Summary</P><P>1. Both peripheral arterial disease (PAD) and coronary artery spasm (CAS) are associated with endothelial dysfunction. Thus, a higher incidence of CAS may be expected in patients with PAD. In the present study, we evaluated the incidence and characteristics of CAS in patients with PAD.</P><P>2. A total of 78 patients with PAD and 241 age- and gender-matched patients without PAD who had chest pain with normal coronary appearance on coronary angiograms underwent intracoronary acetylcholine (ACh) provocation test. Acetylcholine was injected into the left coronary artery in incremental doses of 20, 50 and 100 &mgr;g/min. Significant CAS was defined as a transient > 70% luminal narrowing with concurrent chest pain and/or ST segment changes.</P><P>3. Patients with PAD had a significantly higher incidence of ACh-induced significant CAS than those without PAD (60.3 vs 34.0%, respectively <I>P</I> < 0.001), as well as chest pain and ST segment changes during the ACh provocation test. Patients with PAD were more sensitive to lower doses of ACh and had a higher incidence of multivessel spasm than those without PAD. Multivariable logistic analysis showed that age, current smoking, PAD and myocardial bridge were independent predictors of ACh-induced significant CAS. Moreover, of these factors, PAD was the strongest independent predictor (odds ratio 4.25; confidence interval 1.33–13.54; <I>P</I> = 0.014).</P><P>4. In patients with chest pain, the presence of arterial disease at another site should still push the clinician towards treating the chest pain as angina, even if the coronary anatomy is normal on a coronary angiogram.</P>

      • SCISCIESCOPUS
      • AFB₁ 대사에서 phloretion의 이중 활성 효과

        임대원,이광,고상상,진효연,은상용,최병민,김복량 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.1

        Aflatoxm B₁(AFB₁) is a potent hepatocarcinogen in experimental animals and a hazard to human health in several parts of the world. AFB₁ is activated to its ultimate carcinogenic intermediate, AFB₁-8,9-epoxide, by cytochrome P450(CYP) 1A2 and CYP3A4 in human liver and the intermediate is decomposed by several glutathione S-transferase(GST) including GSTA2, GSTM1 and GSTP1. In this study, we investigated the effects of phloretin on the enzyme systems which are involved in the activation and detoxification of AFB₁. The metabolic intermediate of AFB₁ was measured with HPLC. We found that phloretin could strongly inhibit the activities of CYP 3A4 and CYP1A2 in a dose dependent manner. Phloretin induced the antioxidant-response element(ARE)-mediated gene expression, including GSTs. The expressions of GSTA2, T1, M1, and GSTP1 were induced by 10μM phloretin. The decomposition of AFB₁-8,9-epoxide was measured with GSH conjugating activity of the epoxide. The rate was increased to 1.5 fold when HepG2 cells were treated by 10μM phloretin for 12h. In the mean while, the total GST activitives toward CDNB in HepG2 cells were not changed by the treatment with phloretin. The results demonstrate that phloretin has strong chemopreventive effects against AFB₁ toxicity through the inhibition of AFB₁ activation and induction of GSTs.

      • KCI등재

        눈 형상의 차용에 의한 포스터 디자인 표현 연구

        진위리 ( Chen Wei-li ),임경호 ( Lim Kyung-ho ) 한국디자인트렌드학회 2013 한국디자인포럼 Vol.38 No.-

        오늘날 광고커뮤니케이션 가운데 눈 형상을 이용한 이미지들이 광고 매체 속에서 다양하게 부각되고 있다. 눈은 실제 인간의 의사소통에 있어 마음을 대변하는 창으로써 실질적인 교감을 형성하지만 반대로 시각적 매체 속에서는 하나의 기호 이미지로 전환된다. 이러한 눈을 주제로 한 상징적 이미지들은 점차 많아지고 다양화됐으며, 눈과 관련된 안경이나 안과뿐만 아니라 회사의 로고나 비주얼 예술에서 시각적 볼거리를 제공하는 수단으로 이용되기도 한다. 특히 한 장의 정지장면으로 남게 되는 지면 포스터 광고의 경우 디자이너들이 취하고 있는 눈의 이미지 표현은 상당히 큰 의미를 지니고 있다. 눈은 포스터 디자인의 기호 이미지 중 하나로 사용되어 그 속에 눈의 현대적 개념 및 또 다른 대중문화 형태를 담아내어 포스터의 표현에 있어서 우리의 모습과 이념을 설득력 있게 전달해주고 있다. 눈을 활용한 포스터들은 눈이 가지고 있는 상징적 의미, 눈의 특수한 형태 등의 현대적 감각과 모양, 색, 레이아옷을 통해 여러 가지 감성의 내용을 함축적으로 표현하였다. 또한 눈짓에 따라 다양하게 표현되며, 예술적 메시지를 효과적으로 전할 수 있다. 그에 반해서 눈 이미지는 국내 포스터 디자인에 있어 많이 활용되지 못하고 있는 실정이다. 그 이유로 우선 표현기법이 부족한 것을 들 수 있고 다음으로 눈 이미지가 내포하고 있는 상징적의미가 다소 국한되어 있는 것을 들 수 있다. 따라서 눈에 대한 표현 연구를 통해 현재 국내 포스터의 눈에 대한 표현응용상황 및 눈 이미지의 새로운 의미에 대한 인식상황을 알아보고, 이를 바탕으로 앞으로 눈 이미지 표현의 발전방향을 제시하는데 도움이 되고자 한다. 또한 눈은 수신자의 관심을 끌고 짧은 순간에 시선을 사로잡을 수 있는 포스터 광고의 중요한 매체로서 신체언어보다 더 심도 있게 연구 할 필요성이 있다고 본다. As we know advertising medium is very popular in advertising communication especially the image of the visual . substantial sympathetic eyes of the window stool to have a communication a visual medium also one of the symbols of the images. Subject to these eyes, symbolic image increasingly diversified and associated with the eye glasses meanwhile the company`s logo in the visual arts is provide a visual douse sceness tiller main floor poster advertising in the eyes of the designers taking a fairly large image of representation. Symbol image of the poster design is one of the eyes culture form philosophy and we look in the representation of the poster deliver persuasive. Several sensibility using posters eye has special symbolic means of eyes the form of the implicitly also vary depending on the glance artistic expression and effective messages. According that has been posted on the other hand the eye image implies of representation techniques and symbolic means that somewhat limited for the reason express application situation and the image of the eye on a new thing domestic poster for situation awareness provide direction to the future development of the eye image representation based on if it helpful or not. Body language attract to captivate the attention for brief moment as important medium of advertising posters in depth research.

      • KCI등재

        Clinicopathological features of non-conventional renal cell carcinoma histological subtypes: Learning points from a large contemporary series spanning over three decades

        Ee Jean Lim,Khi Yung Fong,Jingqiu Li,Hong Hong Huang,Kenneth Chen,Kae Jack Tay,Christopher Wai Sam Cheng,Henry Sun Sien Ho,Nye Thane Ngo,John Shyi Peng Yuen 대한비뇨의학회 2022 Investigative and Clinical Urology Vol.63 No.2

        Purpose: To perform a retrospective review of the clinicopathological features of patients with conventional and non-conventional renal cell carcinoma (cRCC and ncRCC). Materials and Methods: A large prospectively maintained uro-oncological registry was accessed to extract clinicopathological data of patients diagnosed with renal tumors who subsequently underwent nephrectomy from 1990–2019. Demographics and operative parameters were extracted. Analyses of overall survival (OS) and cancer-specific survival (CSS) were performed using the Kaplan–Meier method. Cox proportional-hazards analysis was used to identify risk factors which influenced survival. Results: There were a total of 1,686 consecutive nephrectomies which was retrieved, with 1,286 cRCC and 400 ncRCC. The commonest ncRCC subtypes were papillary (n=198, 11.7%), clear cell papillary (n=50, 3.0%) and chromophobe (n=49, 2.9%) RCC. Kaplan–Meier estimates of OS were higher in cRCC (0.74; 95% confidence interval [CI], 0.71–0.78) than ncRCC (hazard ratio, 1.47; 95% CI, 1.16–1.87). Among individual subtypes, chromophobe RCC had the highest 5-year OS (0.90; 95% CI, 0.79–1.0). Among ncRCC subtypes, acquired cystic RCC demonstrated the highest association with end-stage renal failure and hypertension, with the highest CSS. MiT family translocation RCC had the youngest mean age at presentation (45.6±12.8 y) and excellent CSS. Factors associated with increased OS in the entire cohort included shorter operative time, partial nephrectomy and lower tumor stages. Conclusions: This study provides a comprehensive contemporary overview of ncRCCs which are yet poorly characterized, in comparison to cRCCs. Data from this study would contribute towards tailored patient counseling and healthcare resource planning.

      • SCISCIESCOPUS

        Remote Laser-Microwave Synchronization Over Kilometer-Scale Fiber Link With Few-Femtosecond Drift

        Kwangyun Jung,Jiseok Lim,Junho Shin,Heewon Yang,Li-Jin Chen,Kartner, Franz X.,Heung-Sik Kang,Chang-Ki Min,Jungwon Kim IEEE 2014 Journal of Lightwave Technology Vol.32 No.20

        <P>We show the remote synchronization between a mode-locked laser and a microwave source, separated by a hundreds meter- to kilometer-scale fiber link, with few-femtosecond rms timing drift maintained over several hours. In a laboratory test, the measured timing drift between a mode-locked laser and a 2.856-GHz microwave source, separated by a 610-m fiber link, is 2.7 fs rms (0.048 mrad phase drift) over 7 h. The corresponding relative instability in remote laser-microwave synchronization is 7.2 × 10 <SUP>-19</SUP> in 6300 s averaging time, in terms of overlapping Allan deviation. We further installed 1.15-km long fiber links in an accelerator building and measured the relative phase drift at the link outputs in a klystron gallery, which resulted in 6.6-fs and 31-fs rms timing drift maintained over 7 and 62 h, respectively. To achieve this performance, we combined a balanced optical cross-correlator (BOC)-based stabilized fiber link for remote timing transfer and an optical-microwave phase detector (OM-PD) for local optical-to-microwave synchronization. We identified the impact of power and polarization-state drift in the fiber link and amplitude-to-phase conversion in the OM-PD on the link stability. Based on this analysis, possible technical improvements enabling even higher timing precision and stability are identified.</P>

      • KCI등재후보

        How to Write a Strong Case Study: Tips for Winning a Case Competition

        Babak Somekh,Yifan Zhang,Li-Chen Lim,Maria Elena (Maya) Baltazar Herrera Academy of Asian Business (AAB) 2017 Academy of Asian Business Review Vol.3 No.2

        This paper presents personal experiences of faculty advisers in case writing, particularly to those who would like to participate in World Asian Case Competition. Four faculty advisers offered insightful guidelines and ideas to craft a high quality Asian business case study. First, this paper presented some emerging issues in case writing. Second, it discussed the challenges of Chinese business case writing. Third, a few tips are provided to help readers to write a case and to win case competitions. Finally, it addressed one of the challenging topics on how to showcase responsible businesses focusing on emerging issues and implications for case writing.

      • KCI등재

        Ni doped ZnO thin films for diluted magnetic semiconductor materials

        E. Liu,P. Xiao,J.S. Chen,B.C. Lim,L. Li 한국물리학회 2008 Current Applied Physics Vol.8 No.3,4

        Ni doped ZnO (Zn1. xNixO) thin lms were grown on quartz substrates via magnetron sputtering deposition process with the Ni con-of Zn1. xNixO lms were investigated by means of X-ray diraction (XRD), alternating gradient magnetometer (AGM) and photolumi-nescence (PL). A higher magnetic moment was acquired from the annealed Zn1. xNixO lm doped with 5 at.% Ni, which was attributedto a better preferred orientation from a primary phase Ni2+:ZnO in the lm. A relatively more pronounced ZnO(002) peak observedfrom the Zn1. xNixO lm doped with 5 at.% Ni indicated a good crystallinity of the lm, which was attributed to a lower level of Nicontent in the lm as well as the Ni2+ ions substituted for the Zn2+ ions to form Ni2+:ZnO. A slight shift in ZnO(002) peak positionfor the 5 and 10 at.% Ni doped ZnO lms could be due to the distortion of the ZnO lattice caused by the Ni2+ ion substituents forthe Zn2+ ions.

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