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- 저자 : Li Hangyu (검색결과 4 건)
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( Hangyu Gu ),( Shuangchun Li ),( Vincent Havyarimana ),( Dong Wang ),( Zhu Xiao ) 한국인터넷정보학회 2018 KSII Transactions on Internet and Information Syst Vol.12 No.5
In this paper, we propose a novel inter-cell handover approach from a new perspective in dense Heterogeneous and Small Cell Networks (HetSNets). We first devise a cell selection mechanism to choose a proper candidate small cell for the UEs that tend to implement inter-small cell handover (ICH). By exploiting the property of a typical non-concentric circle, i.e., circle of Apollonius, we then propose a novel analytical method for modeling inter-cell handover regions and present mathematical derivation to prove that the inter-small cell handover issues fit the property of the circle of Apollonius. We design an inter-cell handover algorithm (ICHA) by means of our proposed handover model to dynamically configure hysteresis margin and properly implement handover decision in terms of UE’s mobility. Simulation results demonstrate that the proposed ICHA yields lower call drop rate and radio link failure rate than the conventional methods and hence achieve high Handover Performance Indicator (HPI).
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Shida Li,Xueyu Zhang,Shaokui Zheng,Shoupeng Duan,Jun Cui,Hangyu Zhang 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.95 No.-
This study systematically investigated the inhibition mechanism of NaHCO3 for mild steel corrosion in a0.02 M naturally aerated NaCl solution at 40 C (simulating cooling water) and the critical bicarbonate/chloride molar ratio (RC) using visual observations, potentiodynamic polarization curves, andelectrochemical impedance spectroscopy. The corrosion mechanism of an anodic passivefilm formedwith 0.20–0.40 M NaHCO3 (RC = 10) was controlled by a combination of passivation, diffusion, and chargetransfer processes. Electrochemical impedance spectroscopy results showed that, compared to 0.20–0.24 M NaHCO3, a higher NaHCO3 concentration may affect the stability of the passivefilm. A higherchloride concentration of 0.08 M achieved by a higher concentration cycle in the cooling water systemresulted in a lower RC value of 7.5 for NaHCO3. Both NaHCO3 and Na2CO3 showed an identical corrosionmechanism; moreover, the inhibitory effect of Na2CO3 was not dependent on its alkaline pH. Takentogether, thesefindings show the remarkable potential of NaHCO3/Na2CO3 as a commercially available,comparatively cheap, and environmentally acceptable (i.e., no organic pollution, toxicity, oreutrophication risks after discharge) corrosion inhibitor for mild steel in cooling water systems.
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Ting Chen,Lianyu Zhao,Ziyuan Wang,Jishi Zhao,Yan Li,Hangyu Long,Ming Yang 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.90 No.-
A novel geminized amphiphilic polymer containing double cationic head groups and hydrophobic tails ineach structural unit (denoted as PAGBn), has been prepared in our study. The self-assembly behavior onthe solid/liquid interface was investigated by quartz crystal microbalance with dissipation (QCM-D),steady-statefluorescence, dynamic light scattering (DLS) and transmission electron microscope (TEM). Atwo-regime buildup can be observed, where thefirst regime is attributed to the rapid adsorption ofpolymers, while a rearrangements of pre-adsorbed molecules and their aggregation on the surfacedominate the second regime, exhibiting a formation of aggregates in large sizes due to the effect of thecharge density and hydrophobes on the self-assembly process. It exhibits a drastically enhanced killingefficiency of99.9% against both of Staphylococcus aureus and Escherichia coli bacteria for PAGBncompared with other traditional single-chained polymers, through the reinforced synergistic effect ofelectrostatic and hydrophobic interactions, and the formation of large-sized polymer aggregates,encompassing and killing the bacteria more efficiency. Ourfindings reveal the antibacterial mechanismand the correlation between antibacterial activity and aggregates structure, providing a basis for thedevelopment of super-antibacterial materials in the infection resistant applications.
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Mao Minghuan,Yang Liang,Hu Jingyao,Liu Bing,Zhang Xiling,Liu Yili,Wang Ping,Li Hangyu 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-
The neuronally expressed developmentally downregulated 4 (NEDD4) gene encodes a ubiquitin ligase that targets the epithelial sodium channel for degradation and has been implicated in tumor growth in various cancers. Hence, in this study, we intended to characterize the functional relevance of the NEDD4-mediated Kruppel-like factor 8/microRNA-132/nuclear factor E2-related factor 2 (KLF8/miR-132/NRF2) axis in the development of bladder cancer. NEDD4 and KLF8 were overexpressed in bladder cancer tissues and were associated with poorer patient survival rates. In bladder cancer cells, NEDD4 intensified the stability and transcriptional activity of KLF8 through ubiquitination to augment cell viability and migratory ability. Our investigations revealed that NEDD4 promotes the binding of KLF8 to the miR-132 promoter region and inhibits the expression of miR-132. KLF8 inhibited the expression of miR-132 to augment the viability and migratory ability of bladder cancer cells. Furthermore, miR-132 downregulated the expression of NRF2 to restrict the viability and migratory ability of bladder cancer cells. In addition, in vivo findings verified that NEDD4 regulates the KLF8/miR-132/NRF2 axis by accelerating tumor growth and lung metastasis. In conclusion, this study highlights NEDD4 as a potential therapeutic target against tumor recurrence and metastasis in bladder cancer.
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