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      • KCI등재후보
      • Engineering of Guangzhou International Finance Centre

        Kwok, Michael,Lee, Alexis Council on Tall Building and Urban Habitat Korea 2017 International journal of high-rise buildings Vol.6 No.1

        The Guangzhou International Finance Centre (IFC) is a landmark building that symbolizes the emerging international strength of Guangzhou, China's third largest city. It is also one of the dual iconic towers along the main axis of Guangzhou Zhujiang New Town. Arup adopted a total engineering approach in embracing sustainability and aiming at high efficiency solutions based on performance-based design principles covering structures, building services, fire engineering, vertical transportation, and façade performance to constitute an efficient and cost-effective overall building design. Through dynamic integration of architectural and engineering principles, Guangzhou IFC represents a pioneering supertall building in China. It adopts a diagrid exoskeleton structural form that is clearly expressed through the building's façade and gives the building its distinctive character. The aerodynamic shape of the building not only presents the aesthetic quality of elegant simplicity, but also reduces the effects of wind, thereby reducing the size and weight of the structure. State-of-the-art advanced engineering methods, such as optimization techniques and nonlinear finite element modelling, were applied in parallel with large-scale experimental programs to achieve an efficient and high-performance design taking into account the constructability and cost-effectiveness for a project of this scale.

      • KCI등재

        Relative Endowments and the Volume of Trade

        ( Kwok Tong Soo ) 세종대학교 경제통합연구소 (구 세종대학교 국제경제연구소) 2009 Journal of Economic Integration Vol.24 No.4

        This paper provides evidence that the volume of trade may increase as countries` relative endowments become more similar. A model is developed that can explain this phenomenon. The model is a four-good version of the Davis (1995) Heckscher-Ohlin-Ricardo model of international trade based on technological and factor endowment differences across countries. In the model, trade volumes may increase with greater similarity in relative endowments, because productivity differences across countries mean that countries` production becomes increasingly specialised the more similar are their relative endowments.

      • KCI등재
      • KCI등재

        Mediating Effect of Internet Addiction on the Association between Resilience and Depression among Korean University Students: A Structural Equation Modeling Approach

        Kwok Kei Mak,Jae seung Jeong,Hye-Kyung Lee,Koun seok Lee 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.10

        Objective: This study examined the mediating role of internet addiction in the association between psychological resilience and depressive symptoms. Methods: 837 Korean university students completed a survey with items of demographic information, Connor-Davidson Resilience Scale (CD-RISC), Internet Addiction Test (IAT), and Patient Health Questionnaire (PHQ-9) in 2015. The complex associations among psychological resilience, internet addiction, and depressive symptoms were delineated using structural equation models. Results: In the most parsimonious model, the total effect and indirect effect of resilience on depressive symptoms via internet addiction, were statistically significant. The goodness of fit of the measurement model was satisfactory with fit indices, normed fit index (NFI) of 0.990, non-normed fit index (NNFI) of 0.997, comparative fit index (CFI) of 0.998, root mean square error (RMSEA) of 0.018 (90%CI=0.001–0.034); and Akaike Information Criterion (AIC) of -21.049. Conclusion: The association between psychological resilience and depressive symptoms was mediated by internet addiction in Korean university students. Enhancement of resilience programs could help prevent internet addiction and reduce the related depression risks.

      • SCIESCOPUS

        TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and NF-kB pathway in patients with primary Sjogren's syndrome

        Kwok, Seung-Ki,Cho, Mi-La,Her, Yang-Mi,Oh, Hye-Joa,Park, Mi-Kyung,Lee, Seon-Yeong,Woo, Yun Ju,Ju, Ji Hyeon,Park, Kyung-Su,Kim, Ho-Youn,Park, Sung-Hwan BioMed Central 2012 ARTHRITIS RESEARCH AND THERAPY Vol.14 No.2

        <P><B>Introduction</B></P><P>The study was undertaken to investigate the interrelation of toll-like receptor (TLR) and interleukin (IL)-17 in the salivary glands of patients with primary Sjogren's syndrome (pSS) and to determine the role of TLR and IL-17 in the pathophysiology of pSS.</P><P><B>Methods</B></P><P>The expressions of various TLRs, IL-17 and the cytokines involved in Th17 cell differentiation including IL-6, IL-23, tumor necrosis factor-alpha (TNF-α) and IL-1β were examined by immunohistochemistry in salivary glands of pSS patients. The IL-17 producing CD4+ T cells (Th17 cells) were examined by flow cytometry and confocal staining in peripheral mononuclear blood cells (PMBCs) and salivary glands of pSS patients. After PBMCs were treated with TLR specific ligands, the induction of IL-17 and IL-23 was determined using real-time PCR and ELISA. The signaling pathway that mediates the TLR2 stimulated production of IL-17 and IL-23 was investigated by using treatment with specific signaling inhibitors.</P><P><B>Results</B></P><P>We showed that TLR2, TLR4, TLR6, IL-17 and the cytokines associated with Th17 cells were highly expressed in salivary glands of pSS patients but not in controls. The expressions of TLR2, TLR4 and TLR6 were observed in the infiltrating mononuclear cells and ductal epithelial cells, whereas IL-17 was mainly observed in infiltrating CD4+ T cells. The number of IL-17 producing CD4+ T cells was significantly higher in pSS patients both in PBMCs and minor salivary glands. The stimulation of TLR2, TLR4 and TLR6 additively induced the production of IL-17 and IL-23 from the PBMCs of pSS patients especially in the presence of TLR2 stimulation. IL-6, signal transducer and activator of transcription 3 (STAT3) and nuclear factor-kappaB (NF-kB) pathways were implicated in the TLR2 stimulated IL-17 and IL-23.</P><P><B>Conclusions</B></P><P>Our data demonstrate that TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and NF-kB pathway in pSS. Therefore, therapeutic strategies that target TLR/IL-17 pathway might be strong candidates for treatment modalities of pSS.</P>

      • KCI등재후보

        INNER HYBRIDITY IN THE CITY: TOWARD A CRITIQUE OF MULTICULTURALISM

        Kwok-bun Chan 연세대학교 동서문제연구원 2003 Global economic review Vol.32 No.2

        Muddled as an idea and flawed as a public policy, multiculturalism in Canada advocates conformity to a unitary culture in the public place and tolerance of diverse cultures in the private place. This tolerance of cultural heterogeneity in the sphere of the intimate is often upheld as a defining characteristic of Canadian society. Yet multiculturalism is not without criticisms. For one, multiculturalism is at odds with the desire of the children and grandchildren of the Chinese immigrants in Canada to adapt themselves to their host society, thus transforming themselves as well as the larger society. A multicultural policy that continues to hark back to the past turns a blind eye to the fierce generation and gender politics within the Chinese family. Neither does the multicultural policy square well with a more progressive social theory of self, identity and culture that is cognizant of the duality of the psychological make-up of human beings: that one looks backward and forward, committed to preserving roots of the past and exploring routes to the future. As such, the Canadian multicultural policy suffers in a two-fold way: empirical and theoretical. A possible way out is to pursue a Hegelian dialectics that sees culture as an aftermath of a collision of dissimilar cultures, a kind of forced entanglement of things different. We need a new urban social theory that sees integration, fusion, and hybridization ― not assimilation and not cultural pluralism ― as possibie and desirable outcomes. This is a completely different vision of society altogether, a kind of Utopia. We need a public policy that sees a distinct promise of the city in designing institutions and public spaces that promote hybridism in the mind, an inner deliberation, a mental turmoil ― which is not afraid of confronting modem life's many moments of contradictions, ironies and paradoxes.

      • SCIESCOPUSKCI등재

        PLANETARY NEBULAE: NEW CHALLENGES IN THE 21ST CENTURY

        KWOK SUN The Korean Astronomical Society 2005 Journal of The Korean Astronomical Society Vol.38 No.2

        Athough planetary nebulae (PNe) have been discovered for over 200 years, it was not until 30 years ago that we arrived at a basic understanding of their origin and evolution. Even today, with observations covering the entire electromagnetic spectrum from radio to X-ray, there are still many unanswered questions on their structure and morphology. In this review, we summarize recent theoretical and observational advances in PNe research, and discuss the roles of PNe in the chemical (atomic, molecular, and solid-state) enrichment of the galaxy and as tracers of the large scale structure of the Universe.

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