Clinical Usefulness of Korean Red Ginseng in Postmenopausal Women with Severe Climacteric Disturbance

Yoshihiro Kikuchi(Yoshihiro Kikuchi),Takehiko Tode(Takehiko Tode),Junko Hirata(Junko Hirata),Hideyuki Nakata(Hideyuki Nakata),Tsunekazu Kita(Tsunekazu Kita) 고려인삼학회 2003 Journal of Ginseng Research Vol.27 No.3

The aim of this study is to evaluate clinical usefulness of Korean red ginseng (RG) on various postmenopausal syndromes. Total plasminogen inhibitor-1 (tPAI-1) in peripheral blood from 9 postmenopausal women with climacteric syndromes (CS) was measured before and 3 months after treatment with daily oral administrat i on of 6g RG and that from 8 postmenopausal women without any CS was also measured as healthy controls. Blood samples were collected in the early morning on the bed-rest. Psychological conditions of postmenopausal women with CS were measured before and 3 months after treatment with RG using simplified menopausal index (SMI). In addition, OKETSU (blood stagnation) syndrome scores and KI deficiency (generalized energy stagnation) scores proposed by Terasawa et al., were recorded before and 3months after treatment with RG in postmenopausal women with CS and in healthy postmenopausal women. OKETSU syndrome scores and tPAI-1 levels in postmenopausal patients with CS were significantly (P<0.001 and<br/> P<0.01) higher than those in healthy postmenopausal women without CS. Similarly, SMI scores and KI deficiency scores in postmenopausal patients with CS were about three-fold higher than those without any CS. When RG was administered for 3 months, KI deficiency scores and OKETSU scores as well as SMI scores declined around the levels of healthy postmenopausal women. Although tPAI-1 levels significantly (P<0.05) decreased after treatment with RG, those did not reach the levels of healthy postmenopausal women. Clinical usefulness of administration of RG to postmenopausal women with CS was confirmed from evaluation not only by modern medicine but also by traditional KAMPO medicine.

Goniotrichopsis reniformis (Kajimura) Kikuchi comb. nov. (Stylonematales, Rhodophyta) from Japan

신종암,Kikuchi, Norio,West, John A.,Kajimura, Mitsuo,Shin, Jong-Ahm 한국조류학회(藻類) 2006 ALGAE Vol.21 No.2

The morphology and life history of Stylonema reniforme Kajimura (Stylonematales, Rhodophyta) from Japan were investigated and its taxonomic placement was discussed. This species has 6-30 discoid chloroplasts devoid of a pyrenoid in each cell. This is a typical feature of the genus Goniotrichopsis. The species reproduced only by monospores, which were formed by the direct transformation of the vegetative cells similar to the type species Goniotrichopsis sublittoralis Smith. Goniotrichopsis reniformis (Kajimura) Kikuchi comb. nov. was proposed. The asexual life history of the present species was completed in 3-10 weeks at 15-20°C in culture.

전기산업의 에너지문제 해결방안

Kikuchi K 한국에너지협의회 1995 에너지協議會報 Vol.36 No.-

Two new species of Dentilabus Heinrich (Hymenoptera: Ichneumonidae: Ichneumoninae) from Japan and Korea, with redefinition of the genus

KIKUCHI, NAMIKI,KONISHI, KAZUHIKO Magnolia Press 2018 Zootaxa Vol.4524 No.1

<P>We discovered Dentilabus Heinrich (Icneumoninae: Platylabini) for the first time from the Eastern Palearctic region. Two new species, D. nigripodus sp. n. [Japan and Korea] and D. iyoensis sp. n. [Japan] are described. Dentilabus nigripodus resembles its Western Palearctic congener, D. variegatus (Wesmael), but they can be easily distinguished by the uniformly black hind femora in D. nigripodus. With the inclusion of D. iyoensis, we also redefine the generic limits of Dentilabus. A key to Palearctic species of the genus is provided. </P>

A 1-megadalton translocation complex containing Tic20 and Tic21 mediates chloroplast protein import at the inner envelope membrane.

Kikuchi, Shingo,Oishi, Maya,Hirabayashi, Yoshino,Lee, Dong Wook,Hwang, Inhwan,Nakai, Masato American Society of Plant Physiologists 2009 The Plant cell Vol.21 No.6

<P>Chloroplast protein import is mediated by two hetero-oligomeric protein complexes, the Tic and Toc translocons, which are located in the inner and outer envelope membranes. At the inner membrane, many Tic components have been identified and characterized, but it remains unclear how these Tic proteins are organized to form a protein-conducting channel or whether a stable Tic core complex that binds translocating preproteins exists. Here, we report the identification of a 1-megadalton (MD) translocation complex as an intermediate during protein translocation across the inner membrane in Arabidopsis thaliana and pea (Pisum sativum). This complex can be detected by blue native PAGE using the mild detergent digitonin without any chemical cross-linkers. The preprotein arrested in the 1-MD complex can be chased into its fully translocated form after a subsequent incubation. While Tic20 and Tic21 appear to be involved in the 1-MD complex, Tic110, a well-characterized Tic component, exists as a distinct entity from the complex. Several lines of evidence suggest that the 1-MD complex functions in between the Toc and Tic110-containing complexes, most likely as a protein-conducting channel at the inner envelope.</P>

Experimental Study On Seismic Behavior Of Masonry Walls With Column

Kikuchi, Kenji,Park, Kang-Geun 한국공간구조학회 2006 한국공간구조학회지 Vol.6 No.2

본 연구는 보강 조적벽체의 지진거동에 대한 실험적 연구로써, 기둥의 보강, 조적벽체의 보강, 횡하중 높이에 대한 역학적 특성을 분석하였다. 시험체는 구멍이 있는 콘크리트 블록으로 만들었고, 전단 스팬비, 횡하중 높이의 영향, 보강기둥 및 벽체 철근 보강비에 대한 구조적 특성을 파악할 수 있도록 하였다. 벽체의 횡력에 대한 하중점의 벽체 높이의 0.67, 1.08 및 1.1배로 하였다. 수평방향의 철근비는 0, 0.08, 0.18, 수직 방향의 철근비는 0.18, 0.36, 0.64로 하였다. In order to investigate the effect of the height of application point of lateral loads and reinforcing steel bars in walls and columns in improving the seismic behavior of confined concrete block masonry walls, an experimental research program is conducted. A total of twelve one-half scale specimens are tested under repeated lateral loads. Specimens are tested to failure with increasing maximum lateral drifts while a vertical axial load was applied and maintained constant. The specimens adopted are two-dimensional (2D) hollow concrete block masonry walls with different parameters such as shear span ratio, inflection point and percent of reinforcement in confining columns and walls. Test results obtained for each specimen include cracking patterns, load-deflection curve, and strains in reinforcement and walls in critical locations. Analysis of test data showed that above parameters generate a considerable effect on the seismic performance of confined concrete block masonry walls.

Self-Assessment and Working time on Nut Size Distinction Skill of Marine Engineers

KIKUCHI Kazumitsu 제어로봇시스템학회 2022 제어로봇시스템학회 국제학술대회 논문집 Vol.2022 No.11

A rule of thumb for marine engineers is that if a marine engineer has much experience in maintaining machines, the marine engineer can distinguish the size of the tool (spanner or wrench) required for removing machine nuts or bolts by mere observation [1]. This study investigates whether this rule of thumb is related to self-assessment and working time for the distinction of nuts. The participants in this experiment were marine engineering students without practical experience. The experiment included visual and hand conditions. The experiment place was not only a ship engine room but a training room where noise, high temperature, and the smell of fuel oil in the marine engine plant were not experienced by the students. The results showed that the number of the nuts accurately distinguished was unaffected by working hours and self-assessment of the participants who had a boarding history of 12 months on the training ship. Safe operation on marine engine plants must rely on the skills of marine engineers, such as a nut size distinction skill.

Recent trends of healthcare information and communication technologies in pediatrics: a systematic review

Kikuchi Toru,Lee Keehyuck,Hwang Hee 대한소아청소년과학회 2022 Clinical and Experimental Pediatrics (CEP) Vol.65 No.6

As information communication technology (ICT) has advanced, the healthcare industry has embraced it to reduce medical costs, improve health outcomes, and increase patient satisfaction. Healthcare ICT revolutionizes pediatric healthcare. This study aimed to categorize and synthesize findings from the literature regarding the application of ICT in pediatric patients. This systematic review is based on a comprehensive search of Embase, MEDLINE, and Google Scholar. Study selection and coding were performed independently by 2 researchers, followed by narrative categorization. To reflect current trends in ICT for pediatrics, we adopted the Hype cycle technology classification developed by the advisory and information technology firm, Gartner, and the classification of digital health interventions by the World Health Organization. This study included a total of 135 studies. The analysis revealed 7 main types of ICT for pediatrics: (1) telehealth (39 papers), (2) precision medicine (2 papers), (3) automated decision support systems (17 papers), (4) electronic health records (7 papers), (5) patient portals (7 papers), (6) artificial intelligence (AI) (39 papers), and (7) mobile and wearable technologies (20 papers). In particular, we consistently found references to ICT for pediatrics as well as changing and improving healthcare for children. Further studies are required to determine how we can improve ICT productivity for pediatrics, particularly through AI. This study’s results will help healthcare delivery organizations and technology companies consider the future direction of pediatric healthcare.

Design of Seismic Isolated Tall Building with High Aspect-Ratio

Kikuchi, Takeshi,Takeuchi, Toru,Fujimori, Satoru,Wada, Akira Council on Tall Building and Urban Habitat Korea 2014 International journal of high-rise buildings Vol.3 No.1

When seismic isolation system is applied to high aspect-ratio (height/wide-ratio) steel structures, there are several problems to be taken into consideration. One is lifting up tensile force on the isolation bearing by overturning moment caused by earthquake. Another is securing building stiffness to produce seismic isolation effects. Under these conditions, this paper reports the structural design of high-rise research building in the campus of Tokyo Institute of Technology. With the stepping-up system for the corner bearings, the narrow sides of single span framework are designed to concentrate the dead load as counter-weight for the tensile reaction under earthquake. Also we adopted concrete in-filled steel column and Mega-Bracing system covering four layers on north & south framework to secure the horizontal stiffness of the building.

Satellite Digital Sound Broadcasting System for Mobile Users in Japan

Kikuchi, Hideo,Yamaguchi, Yoshitake 통신위성우주산업연구회 2002 Joint Conference on Satellite Communications Vol.2002 No.-

Satellite digital sound broadcasting system for mobile users using 2.6GHz radio frequency band is planned to be serviced in early 2004 in Japan. This system enables many users in mobile environment to receive a large number of various multimedia broadcasting programs such as high quality digital audio programs and MPEG-4 video programs with vehicular and very small portable receivers. In order to realize this service, a geostationary satellite with high power transponder and high gain large deployable antenna is used. Terrestrial repeaters, which retransmit broadcasting signal to the areas where the satellite signal is blocked by obstacles, are also used in urban areas. CDM (Code Division Multiplex) technique and RAKE receivers are sued for effective utilization of spectrum as well as mitigation of multipath fading. A variety of verification tests including field tests have been carried out for past several years to evaluate the system performance. In this paper, recent development status of the system is described.