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      • SCOPUSKCI등재

        Performance Embodiment of Acrylic Material in Art Painting Creation

        Xie, Ke Korean Chemical Society 2021 대한화학회지 Vol.65 No.2

        In art painting creation, painting material is an important carrier. Acrylic as a young material has very wide applications in modern art. This study mainly analyzed the properties of acrylic material. Firstly, the emergence and development of acrylic were introduced, and then its material characteristics were analyzed. Finally, the performance embodiment of acrylic paintings was compared with oil paintings and watercolor paintings. It was found that acrylic paintings not only had some advantages of oil and watercolor paintings but also had own style characteristics; acrylic paintings also have advantages in durability and flexibility; acrylic paintings could present the characteristics that oil and watercolor paintings did not have while realizing the techniques of them. Acrylic paintings have a broad development space in art creation, which is worth further attention and promotion.

      • Expression of ERCC1, MSH2 and PARP1 in Non-small Cell Lung Cancer and Prognostic Value in Patients Treated with Platinum-based Chemotherapy

        Xie, Ke-Jie,He, Hong-Er,Sun, Ai-Jing,Liu, Xi-Bo,Sun, Li-Ping,Dong, Xue-Jun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6

        Purpose: To evaluate the prognostic value of the expression of excision repair cross-complementation group l (ERCC1), MutS protein homolog 2 (MSH2) and poly ADP-ribose polymerase 1 (PARP1) in non-small-cell lung cancer patients receiving platinum-based postoperative adjuvant chemotherapy. Methods: Immunohistochemistry was applied to detect the expression of ERCC1, MSH2 and PARP1 in 111 cases of non-small cell lung cancer paraffin embedded surgical specimens. Through og-rank survival analysis, we evaluated the prognostic value of the ERCC1, MSH2, PARP1 and the related clinicopathological factors. COX regression analysis was used to determine whether ERCC1, MSH2 and PARP1 were independent prognostic factors. Results: In the enrolled 111 non-small cell lung cancer patients, the positive expression rate of ERCC1, MSH2 and RARP1 was 33.3%, 36.9% and 55.9%, respectively. ERCC1 (P<0.001) and PARP1 (P=0.033) were found to be correlated with the survival time while there was no correlation for MSH2 (P=0.298). Patients with both ERCC1 and PARP1 negative cancer had significantly longer survival time than those with ERCC1 (P=0.042) or PARP1 (P=0.027) positive alone. Similalry, the survival time of patients with both ERCC1 and PARP1 positive cancer was shorter than those with ERCC1 (P=0.048) or PARP1 (P=0.01) positive alone. Conclusion: Patients with ERCC1 or PARP1 negative non-small cell lung cancer appear to benefit from platinum-based postoperative adjuvant chemotherapy.

      • 音乐教育对幼儿情商培养的影响分析

        谢科(Ke Xie) 국민대학교 한반도미래연구원 2022 한반도미래연구 Vol.특별호 No.-

        The goal of education is to cultivate a well-rounded and harmonious person. In the course of more than ten years of teaching, it is found that many students have high IQ, strong learning ability, excellent performance, but weak social, cooperation, organization and coordination ability of low emotional intelligence phenomenon. In such an environment over time, the student is easy to have problems in learning communication and interpersonal, influence the students establish good psychological quality of human relationships, severe cases can lead to mental health problems, at the same time, it is not in conformity with the Chinese students in the development of core literacy cultivation of “all-round development of people” education goals. Therefore, the cultivation of emotional intelligence is very crucial and important in the process of children's growth and education. Music is an art of expressing emotions, it is able to link the human feelings, and emotional intelligence is a personal emotional mind power, using music the art of “emotion”, help children to open the doors of the emotional communication, let the students feel the music in the music activities in rich emotions and different forms of music to understand different ways of emotional expression, and rich emotional world. Early childhood is a critical period for brain development, and also a sensitive period for music. At the same time, emotional intelligence is also formed in early childhood. Therefore, the influence of music education on emotional intelligence is particularly important. This paper analyzes the influence of music education on children's emotional intelligence training, analyzes and studies how to cultivate children's emotional intelligence through music, so as to achieve the educational goal of students' all-round development. 教育的目标是培养素质全面、身心和谐的人。在十几年教学的过程中发现许多学生出现了智商高、学习能力强、成绩优异,但社交、合作、组织协调能力薄弱的低情商现象。在这样的环境下久而久之,学生会容易在学习交流和人际交往上遇到问题,影响了学生建立良好人际关系的心理品质,严重的情况下可能会产生心理健康问题,同时也不符合中国学生发展核心素养中培养“全面发展的人”的教育目标。因此,情商的培养在孩子成长教育的过程中就十分关键及重要了。音乐是表达情感的一门艺术,它能够链接人类的内心情感,而情商是一个人心灵情感的力量,利用音乐这门“情感艺术”,帮助孩子打开情感交流的大门,在音乐活动中让学生感受到音乐中丰富的情感以及不同形式音乐了解不同的情感表达方式,从而丰富情感世界。幼儿时期是大脑发育的关键时期,也是音乐的敏感期,同时情商也形成于婴幼儿时期,因此,幼儿的音乐教育对情商培养的影响尤为重要。本文针对音乐教育对幼儿情商培养的影响进行分析,分析及研究如何通过音乐的方式对幼儿进行情商培养,从而实现学生全面发展的教育目标。

      • Internal force monitoring design of long span bridges based on ultimate bearing capacity ratios of structural components

        Hu, Ke,Xie, Zheng,Wang, Zuo-Cai,Ren, Wei-Xin,Chen, Lei-Ke Techno-Press 2018 Structural monitoring and maintenance Vol.5 No.1

        In order to provide a novel strategy for long-span bridge health monitoring system design, this paper proposes a novel ultimate bearing capacity ratios based bridge internal force monitoring design method. The bridge ultimate bearing capacity analysis theories are briefly described. Then, based on the ultimate bearing capacity of the structural component, the component ultimate bearing capacity ratio, the uniformity of ultimate bearing capacity ratio, and the reference of component ultimate bearing capacity ratio are defined. Based on the defined indices, the high bearing components can then be found, and the internal force monitoring system can be designed. Finally, the proposed method is applied to the bridge health monitoring system design of the second highway bridge of Wuhu Yangtze river. Through the ultimate bearing capacity analysis of the bridge in eight load conditions, the high bearing components are found based on the proposed method. The bridge internal force monitoring system is then preliminary designed. The results show that the proposed method can provide quantitative criteria for sensors layout. The monitoring components based on the proposed method are consistent with the actual failure process of the bridge, and can reduce the monitoring of low bearing components. For the second highway bridge of Wuhu Yangtze river, only 59 components are designed to be monitored their internal forces. Therefore, the bridge internal force monitoring system based on the ultimate bearing capacity ratio can decrease the number of monitored components and the cost of the whole monitoring system.

      • Prognostic Values of VEGF and Endostatin with Malignant Pleural Effusions in Patients with Lung Cancer

        Zhang, Yu,Yu, Li-Ke,Lu, Guo-Jun,Xia, Ning,Xie, Hai-Yan,Hu, Wei,Hao, Ke-Ke,Xu, Chun-Hua,Qian, Qian Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19

        Aims: Angiogenesis is important in malignant pleural effusion (MPE) formation and it is regulated by a number of pro- and anti-angiogenic cytokines. The purpose of this study was to evaluate the prognostic value of angiogenic factor vascular endothelial growth factor (VEGF) and angiogenesis inhibitor endostatin in lung cancer patients with MPE, and investigate the relationship between these two kinds of agent. Methods: Using enzyme-linked immunoadsorbent assay, the concentrations of VEGF and endostatin were measured in pleural effusions (PE) and serum from a total of 70 lung cancer patients with MPE and 20 patients with tuberculosis. Results: Compared to patients with tuberculosis, the levels of VEGF and endostatin in both PE and serum were significantly higher in patients with lung cancer. There were statistically significant correlations between VEGF levels in PE and serum (r=0.696, p<0.001), endostatin levels in PE and serum (r=0.310, p=0.022), and VEGF and endostatin levels in PE (r=0.287, p=0.019). Cox multivariate analysis revealed that elevated pleural VEGF and endostatin levels and serum endostatin level were independent predictors of shorter overall survival. Conclusion: Both pro- and anti-angiogenic factors are likely contributors to PE formation. Our results suggest that the levels of VEGF and endostatin in PE, together with endostatin in serum, may be potential prognostic parameters for lung cancer patients with MPE.

      • Microsatellite primers in red bayberry, <i>Myrica rubra</i> (Myricaceae)

        Xie, Xiaobo,Qiu, Yingying,Ke, Liping,Zheng, Xiliang,Wu, Guanting,Chen, Jinqing,Qi, Xingjiang,Ahn, Sangnag Wiley (John WileySons) 2011 American journal of botany Vol.98 No.4

        <P>Microsatellite markers were developed in Myrica rubra to investigate potential hybridization events within or between M. rubra and its closely related species.</P>

      • KCI등재

        Electrochemical Behavior of Norfloxacin and Its Determination at Poly(methyl red) Film Coated Glassy Carbon Electrode

        Ke-Jing Huang*,Chun-Xuan Xu,Wan-Zhen Xie 대한화학회 2008 Bulletin of the Korean Chemical Society Vol.29 No.5

        A poly(methyl red) film-modified glassy carbon electrode (PMRE) was fabricated for determination of norfloxacin (NFX). The electrochemical behavior of NFX was investigated and a well-defined oxidation peak with high sensitivity was observed at the film electrode. PMRE greatly enhanced the oxidation peak current of NFX owing to the extraordinary properties of poly(methyl red) film. Based on this, a sensitive and simple voltammetric method was developed for measurement of NFX. A sensitive linear voltammetric response for NFX was obtained in the concentration range of 1 10-6-1 10-4 mol/L and the detection limit was 1 10-7 mol/L using linear sweep voltammetry (LSV). The proposed method possessed advantages such as low detection limit, fast response, low cost and simplicity. The practical application of this new analytical method was demonstrated with NFX pharmaceuticals.

      • THE EFFECTIVENESS OF GLOBAL BRANDS SOCIAL MEDIA COMMUNICATION IN CHINA: EVIDENCE FROM WEIBO

        Ke Chen,Yi Xie,Luping Zhu,Zhuzhu Xu 글로벌지식마케팅경영학회 2018 Global Marketing Conference Vol.2018 No.07

        Introduction Social media communication has become a popular way for firms to engage with customers. Research shows that firms/brands engagement with fans or customers on social media is effective to improve brand equity (Kim & Ko, 2012), drive sales (eMarketer, 2015), and enhance both transactional and relational customer behaviour (Kumar, Bezawada, Rishika, Janakiraman, & Kannan, 2016). Given the influences of social media communication, how brands effectively engage with fans or followers on social media is an important question for marketers. Most research on this topic is from the applied psychology and consumer behaviour literature, whose theories and content are dominantly tested in laboratory setting. Very few research (e.g., Lee, Hosanagar, & Nair, 2017) applied real behaviour data of field settings to study this issue. Additionally, existent research primarily focuses on social media like Facebook and Twitter in developed counties. To our knowledge, no research examines global brands social media communications in developing country, like China. Due to the policy constraints, people in mainland China have no access to foreign social media platforms. There is a local social media platform in China, named Weibo. Weibo is a NASDAQ-listed company and has nearly 100 million active users monthly. Many brands, both global and local ones, have created Weibo accounts and keep engaging with their fans. For example, there are 1,452 luxury brands and 3,707 beverage brands or firms on Weibo (Weibo Data Centre, 2017). This paper focuses on global brands’ communication practices on Weibo. The purpose of this paper is to analyse how brand posts that global brands put on their social media page are correlated with fan engagement. By using real data form Weibo, we answer the following questions: (1) what attributes of brand posts on Weibo do affect fan engagement with global brands? (2) how do these attributes affect fans engagement behaviour (i.e. liking, sharing, and commenting) differently? Conceptual Framework We decompose the attributes of global brand social media posts into five aspects, which are proposed to affect fans engagement. The first two aspects, interactivity and vividness, are derived from computer-mediated-communication research (Frotin & Dholakia, 2005; Hoffman & Novak, 1996). The next two, informative and emotional attributes, are developed from the literature of advertising (Hong, Muderrisoglu, & Zinkhan, 1987; Geuens, Pelsmacker, & Faseur, 2011). The last one is localization-related attributes, which is from global marketing communication literature (Kanso & Nelson, 2002) to capture the special characteristics of global brand posts on a local social media platform. We argue that all these five aspects of global brand posts affect fans engagement on brand page. Fans engagement is conceptualized as fans behavioural response to brand posts, which will influence attitude and behaviour of other fans. There are three kinds of fans responses on brands social media page, i.e., liking, sharing and commenting. We do control the time and date of post issued, the text length of post, whether having celebrity in post, whether related to a remarkable event, the number of followers of brand on Weibo, and product category. Interactivity Interactivity is defined as “the degree to which two or more communication parties can act on each other, on the communication medium, and on the messages and the degree to which such influences are synchronized” (Liu & Shrum 2002, p.54). Interactivity requires two-way interaction between not only customers and companies, but customers themselves (Hoffman & Novak, 1996). Brand posts on Weibo differ in the degree of interactivity. Some posts only have text, picture, or video to deliver messages of brands, which has no possibility to interact with fans. Some posts include a link that fans can click to get more information, which enhances the interactivity of communication. Other posts have questions, which stimulate interaction with fans and followers. There are posts inviting people to indicate their like or comment on social media, which are considered as high interactivity as well. Advertising research has found the positive correlation between interactivity of ads and consumers’ attitude (Coyle & Thorson, 2001). De Vries, Gensler and Leeflang (2012) found interactivity of brand post on brand fan pages partially positively related to brand popularity (measured by number of likes and comments). Empirical research (Lee et al., 2017) using Facebook data showed that having links negatively associated with customer engagement, and having questions increased comments but reduced likings. For the inconsistent findings in the literature, we re-examine this relationship by focusing on global brands on a not well-examined Chinese social media, Weibo. Vividness Vividness refers to the format richness of the message (Daft & Lengel, 1986; Fortin & Dholakia, 2005). As for brand posts, vividness is reflected by the number of sensory dimensions and senses presented (text, colours, pictures, and videos, etc.). The degree of vividness influences what and how multiple senses are stimulated (Coyle & Thorson, 2001). For example, a picture post will activate more senses than a text post because the former has colour that stimulates sight more vividly than the later. Vividness is related to but differs from interactivity. Interactivity focuses on the characteristic of two-way interaction of the communication, while vividness stands for the multiple senses stimulated by the communication. Some advertising research found that a vivid web advertisement results in higher attention and more clicks (Lohtia, Donthu, & Hershberger, 2003). As a result, we differentiate vividness of each post and predict that more vivid post associated with higher customer engagement. A vivid post attracts more likes, shares and comments. Localization-related attributes Localization-related attributes are symbols that posts have reflecting the characteristics of local culture and people. The debate of globalization (standardization) versus localization has lasted several decades. Even though a global standardized marketing strategy saves money and gains scale economy, the localization approach (Keegan, 1969) is supported by the reality that each market has unique tastes. In the international advertising literature, some scholars found that many multinational firms “plan globally and act locally” (Blackwell, Ajami, & Stephan, 1991). “Global-local dilemma” exists when global luxury brands internationalize into the Chinese market (Liu et al., 2016). The marketing communication research found that it is not advised for global brands to use the same appeals and symbols in advertising across different countries (Kanso & Nelson, 2002). In other words, the combination of global advertising theme and local communication expertise can result in enhanced effectiveness. We propose, on Weibo, people are more actively engaged to like, share, or comment global brand posts when Chinese elements, such as Chinse handwriting, Chinese festivals, and Chinese celebrity spokespeople, are present. Informative attributes Besides interactivity and vividness, which capture the format characteristics of global brand posts, content-related attributes are associated with customer engagement as well. Informative content is an important side of content attributes. One important function of brand posts is to deliver messages to customers. Research shows that on social networks people tend to have positive attitudes towards informative ads (Taylor, Lewin, & Strutton, 2011). Global brand posts with specific information should result in higher customer engagement than less informative posts. Additionally, global brand posts on social media may have different types of marketing information, such as product, price, promotion and placerelated ones respectively. The posts with varying degree of informative content may change customer engagement as well. Emotional attributes Emotional attributes are another side of the content characteristics of brand posts besides informative ones. Advertising research shows that using emotion appeal in ads is an effective way to gain people attention and generate actions (Holbrook & Batra, 1987). Emotional connections between customers and brands are considered more stable than cognitive association (Heath, Brandt, & Nairn, 2006). Some scholars find that emotional appeal on banner advertising result in positive effects on click-through rates in both B2B and B2C contexts (Lohtia et al., 2003). Empirical research (Lee et al., 2017) on Facebook shows that perceived emotion in brand posts strongly boost users’ likes and comments. Similarly, we propose that emotional attributes of global brand posts on Weibo are correlated with fans engagement. We conceptualize emotional attributes with three elements, emotional tone, emotional icon and emotional core. Emotional core reflects the type of emotions, such as humour, happiness, and love, etc. Emotional tone stands for the strength of emotion, i.e. the emotion is weak or strong. Emotional icon refers to whether the content of posts has emotional symbols, which can take form of icons or net slangs. Research Design Operationalization Dependent variables Customer engagement is operationalized as three variables, the number of likes, the number of shares, and the number of comments of each global brand post. Independent variables Vividness. Vividness is operationalized as four categories standing for different vividness degree, text only, (text and) static picture, (text, static and) animated picture, (text, picture and) video. Interactivity. Interactivity is operationalized as five 0-1 variables, having link, having question, having invitation/incentive to like, having invitation/incentive to share, having invitation/incentive to comment. Localization-related attributes. This part is operationalized as four 0-1 variables, having Chinese culture image, having Chinese culture colour, having Chinese festival, and having Chinese celebrity spokespeople (we include celebrity as a control variable). Informative attributes. This part is operationalized as seven 0-1 variables, whether a post having information of (1) brand name, (2) promotion/trial, (3) price, (4) segmentation, (5) product lunch time, (6) purchase distribution, and (7) public relation event. Emotional attributes. This part is operationalized as three variables, (1) emotional icon, a 0- 1 variable, having emotional symbols or not, (2) emotional core, a categorical variable, different type of emotions identified by surveyed respondents, and (3) emotion tone, a scalerating variable from 1 to 3, standing for none, weak and strong emotion. Control Variables. There are five control variables, (1) time of posts, including date and hour; (2) length of posts, i.e., the number of Chinese characters; (3) celebrity, whether there is a celebrity in a post; (4) event, whether a post is related to a remarkable event; (5) the number of fans of brand, and (6) product category (3 dummy variables to differentiate four categories). Data We chose 6 global brands across five product categories, specifically, beverage (Coca-cola and Starbucks), cosmetics (Olay and L’Or?al), and sports (Nike and Adidas). All these global brands created Weibo account before 2012 and have cumulated a large number of followers. We select the posts from Sept. 1, 2016 to Feb. 28, 2017, within 6 months. This time duration is long enough to get analytical data. This period covers main Chinese traditional festivals, such as Mid-Autumn Festival, National Day, and Chinse New Year, which results in more variances in localization-related variables. Data were collected through two stages. The first stage was to download raw data from Weibo’s brand pages with Internet worm program directly. Each brand has its page which contains all posts it issued and the number of people’s likes, shares, and comments for each post. The second stage is to code content and get the final dataset. Most of 0-1 variables, such as interactivity, localization-related attributes, and informative attributes were coded by two research assistants. Variables of vividness were also coded by them. Variables of emotional attributes were coded by a survey to ask 500 Weibo users. This survey-based coded method is well applied in published research (e.g., Kumar et al., 2016; Lee et al., 2017). Model The three dependent variables, the numbers of likes (y1), shares (y2), and comments (y3), are count data with a Poisson distribution. As a result, the basic model is as following: ?ij = ? + ???(Σ3p=1 ?1p ?????pj + Σ5q=1 ?2q ?????qj + Σ4r=1 ?lr ?????rj + Σ7s=1 ?4s ????sj + Σ3p=1 ?5t ????tj + ?6 ????j + ?7 ????j + ?8 ???j + ?9 ????j + ?10 ?????j + ?11 #??????j + Σ4u=1 ?12u ??????uj) + ?ij (1) Expected Results This research is among the first initiative to examine social media communication in China. We are still working on the data analysis so far. We intend to identify the influence of global posts on fans engagement, which are from not only the content of posts (informative and emotional attributes), but also the design of posts (vividness and interactivity), and especially the localization considerations. We expect to find that the content foci differ fans engagement. Posts of sales promotion should be more effective to enhance fans engagement than those of product demonstration. We can identify what form of posts stimulates fans participation more effectively. We will know whether a video post is more effective than a picture post. Most interestingly, we will know how the posts combined with Chinese cultural elements on social media are responded. For example, we could compare the difference between posts having foreign and local celebrity people. We will know how different customer engagement behaviour influence by the same characteristic of posts. We can identify the most influential factors to each of three customer responses (liking, sharing, and commenting). Comparing with the research using data from Facebook or other social media outlets, we can obtain implications guiding global brands to implement social media strategy across countries.

      • KCI등재

        Bibliometric analysis of researches on traditional Chinese medicine for coronavirus disease 2019 (COVID-19)

        Ke-Lu Yang,Xin-Yao Jin,Ya Gao,Jin Xie,Ming Liu,Junhua Zhang,Jin-Hui Tian 한국한의학연구원 2020 Integrative Medicine Research Vol.9 No.3

        Background: The coronavirus disease 2019 (COVID-19) has caused a worldwide pandemic, and traditional Chinese medicine (TCM) has played an important role in response. We aimed to analyze the published literature on TCM for COVID-19, and provide reference for later research. Methods: This study searched the CBM, CNKI, PubMed, and EMBASE from its establishment to March 11, 2020. VOSviewer 1.6.11 and gCLUTO 2.0 software were used to visually analyze the included studies. Results: A total of 309 studies were included, including 61 journals, 1441 authors, 277 institutions, and 27 provinces. Research collaborations among regions were among those close in geographical distance. The collaborations of institutions and authors were more likely to be restricted to the same region. Among the authors with frequency greater than two (65 authors), only 19 authors had connection with others. More than 70% (358/491) of keywords were only presented once, and 20 keywords were shown more than 10 times. Five research topics were identified: Data mining method based analysis on the medication law of Chinese medicine in prevention and management of COVID-19; exploration of active compounds of Chinese medicine for COVID-19 treatment based on network pharmacology and molecular docking; expert consensus and interpretation of COVID-19 treatment; research on the etiology and pathogenesis of COVID-19; and clinical research of TCM for COVID-19 treatment. Conclusion: The research hotspots were scattered, and the collaboration between authors and institutions needed to be further strengthened. To improve the quality and efficiency of research output, the integration of scientific research and resources, as well as scientific collaboration are needed.

      • SCIESCOPUSKCI등재

        Analysis of Switching Clamped Oscillations of SiC MOSFETs

        Ke, Junji,Zhao, Zhibin,Xie, Zongkui,Wei, Changjun,Cui, Xiang The Korean Institute of Power Electronics 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.3

        SiC MOSFETs have been used to improve system efficiency in high frequency converters due to their extremely high switching speed. However, this can result in undesirable parasitic oscillations in practical systems. In this paper, models of the key components are introduced first. Then, theoretical formulas are derived to calculate the switching oscillation frequencies after full turn-on and turn-off in clamped inductive circuits. Analysis indicates that the turn-on oscillation frequency depends on the power loop parasitic inductance and parasitic capacitances of the freewheeling diode and load inductor. On the other hand, the turn-off oscillation frequency is found to be determined by the output parasitic capacitance of the SiC MOSFET and power loop parasitic inductance. Moreover, the shifting regularity of the turn-off maximum peak voltage with a varying switching speed is investigated on the basis of time domain simulation. The distortion of the turn-on current is theoretically analyzed. Finally, experimental results verifying the above calculations and analyses are presented.

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