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      • Age and Wavelength Dependence of Intraocular Straylight

        Nao Tsuchiya,Tomonori Tashiro,Tomoharu Ishikawa,Kazuhiko Ohnuma,Miyoshi  Ayama 한국색채학회 2017 AIC 2017 Jeju Vol.2017 No.10

        Intraocular straylight is the light scattered in the eye. There are some causes to produce it. Main cause of it is forward scattering by the ocular media. It leads to decline the QOL, thus the QOV as well. So it is important to develop the quantitative measurement method and simplified measurement device. In this study, we estimated the amount of intraocular straylight using a veiling method with an edgeless test stimulus and examined the age and wavelength dependence. Results indicate that intraocular straylight increases with age as expected. About the wavelength dependence, relative decrease from short to middle wavelength range seems to follow Rayleigh scattering, while it stays in about the same level from middle to long wavelength region.

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        High Dose Three-Dimensional Conformal Boost Using the Real-Time Tumor Tracking Radiotherapy System in Cervical Cancer Patients Unable to Receive Intracavitary Brachytherapy

        박희철,Shinichi Shimizu,Akio Yonesaka,Kazuhiko Tsuchiya,Yasuhiko Ebina,Hiroshi Taguchi,Norio Katoh,Rumiko Kinoshita,Masayori Ishikawa,Noriaki Sakuragi,Hiroki Shirato 연세대학교의과대학 2010 Yonsei medical journal Vol.51 No.1

        Purpose: The purpose of this study is to evaluate the clinical results of treatment with a high dose of 3-dimensional conformal boost (3DCB) using a real-time tracking radiation therapy (RTRT) system in cervical cancer patients. Materials and Methods: Between January 2001 and December 2004, 10 patients with cervical cancer were treated with a high dose 3DCB using RTRT system. Nine patients received whole pelvis radiation therapy (RT) with a median dose of 50 Gy (range, 40-50 Gy) before the 3DCB. The median dose of the 3DCB was 30 Gy (range, 25-30 Gy). Eight patients received the 3DCB twice a week with a daily fraction of 5 Gy. The determined endpoints were tumor response, overall survival, local failure free survival, and distant metastasis free survival. The duration of survival was calculated from the time of the start of radiotherapy. Results: All patients were alive at the time of analysis and the median follow-up was 17.6 months (range, 4.9-27.3 months). Complete response was achieved in nine patients and one patient had a partial response. The 1- and 2-year local failure free survival was 78.8% and 54%, respectively. The 1- and 2-year distant metastasis free survival was 90% and 72%, respectively. Late toxicity of a grade 2 rectal hemorrhage was seen in one patient. A subcutaneous abscess was encountered in one patient. Conclusion: The use of the high dose 3DCB in the treatment of cervical cancer is safe and feasible where intracavitary brachytherapy (ICBT)is unable to be performed. The escalation of the 3DCB dose is currently under evaluation.

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