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      • KCI등재

        Bilateral Sacrospinous Hysteropexy Versus Bilateral Sacrospinous Ligament Fixation with Vaginal Hysterectomy for Apical Uterovaginal Prolapse

        Kaiyue Wang,Lijuan Shi,Zheren Huang,Yun Xu 대한배뇨장애요실금학회 2022 International Neurourology Journal Vol.26 No.3

        Purpose: The aim of this retrospective study was to compare the anatomical and functional outcomes between bilateral sacrospinous hysteropexy (BSHP) and bilateral sacrospinous ligament fixation with vaginal hysterectomy (BSLF/VH) in women with apical-predominant uterovaginal prolapse. Methods: Clinical data from patients with symptomatic Pelvic Organ Prolapse-Quantification (POP-Q) stage 2 or higher uterovaginal prolapse who underwent either BSHP (48 patients) or BSLF/VH (69 patients) between January 2014 and December 2018 were reviewed retrospectively. The primary outcome was the subjective satisfaction rate evaluated by Patient Global Impression of Improvement, and the secondary outcomes included objective anatomical success rates, impact on disease-specific quality of life evaluated by the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire-12, Pelvic Floor Distress Inventory-Short Form 20, and Pelvic Floor Impact Questionnaire 7, and surgical complications. Results: After a median follow-up of 35 months (range, 25–58 months), all patients in both groups demonstrated significant postoperative improvements in anatomical and functional outcomes (P<0.001). There were no significant differences in postoperative subjective and objective results, sexual satisfaction outcomes, or disease-specific quality of life between the BSHP and BSLF/VH groups, and similar incidence rates of intraoperative and postoperative complications were also recorded. Conclusions: The uterus-sparing BSHP procedure yielded noninferior anatomical and functional outcomes compared to the BSLF/VH procedure and could be adopted as an alternative to conventional hysterectomy-based native-tissue repair modalities for symptomatic apical-predominant uterovaginal prolapse.

      • KCI등재

        Amino-modified carbon dots as a functional platform for drug delivery: Load-release mechanism and cytotoxicity

        Nana Shi,Kaiyue Sun,Zedi Zhang,Juan Zhao,Lina Geng,Yuhua Lei 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.101 No.-

        Carbon dot (CDs) were prepared for carrying DOX (Doxorubicin) or FAC (Ferric ammonium citrate), andthe loading mechanism and release kinetics of CDs-drugs were studied. CDs were prepared using peonypollen and urea, and characterized by TEM, XRD, 13C NMR, XPS, UV, FT-IR, DLS and zeta potential. Theobtained CDs were rich of –NH2 group on the surface, amorphous phase, spherical morphology withthe diameter about 5 nm, and had a blue fluorescence with the quantum yield (QY) of 12%. Iron disorderscan cause cancer or anemia. DOX is used for treating cancer, but has severe side effects. FAC is an ironsupplement agent, but had low bioavailability. CDs carried DOX (or FAC) through –N=C– (or –CONH–)bond, had high loading efficiency for DOX (37.2%) and FAC (54.0%) by optimizing mass ratios of mCDsto mdrug and reacted overnight. Cellular experiments showed that CDs-drugs had lower cytotoxicity thanfree drugs and CDs co-located with the drug. In vitro release indicated that CDs-DOX had pH-targetedproperty and CDs-FAC could be absorbed easily. CDs-drug release belonged to Weibull model, and releasemechanism was determined by the bonding way between CDs and drug. CDs had potential applicationsin delivery drugs with –C=O or –COOH group.

      • KCI등재

        Study on the doping mechanism and electronic structure for Nb5+ doping PbWO4 crystals

        Teng Chen,Kaiyu Xu,Dongli Shi,Mingjie Wang,Tingyu Liu 한국물리학회 2010 Current Applied Physics Vol.10 No.1

        The existing forms of the impurity Nb5+ in the Nb5+:PbWO4 (PWO) crystals are simulated by computer technology. The possible various kinds of defects in the Nb5+:PWO crystals are also simulated. By analyzing the calculation results of defect formation energies and binding energies, the optimal substitution positions of the Nb5+ ions and the charge compensating mechanism [Nb-w+V2+ o +Nb-w] in the Nb5+:PWO crystals were obtained. The electronic structures for Nb5+:PWO were calculated with density functional theory code CASTEP. It shows that the doping of Nb5+ ions could suppress the 350 nm absorption band.

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        A review of the recent advances in design of corrugated plate packs applied for oil–water separation

        Yunrui Han,Limin He,Xiaoming Luo,Yuling Lü,Kaiyue Shi,Jianheng Chen,Xin Huang 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.53 No.-

        The paper reviews the contradictions and problems existing on the oil–water separation technology in detail from the perspective of experiments, numerical simulation and coalescence mechanism analysis, and the future research directions are forecasted. The review points out that the law of droplet coalescence on the corrugated plates can be studied from the perspective of microscopic experiment and mechanism research, which are the theoretical bases for clarifying the coalescence mechanism of the corrugated plates and refining the droplet coalescence mathematical model. The further research topics are also clarified to promote future applications by combining the coalescence technology with surface bionic technology.

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