http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Zedi Zhang (검색결과 1 건)
- 무료
- 기관 내 무료
- 유료
-
Nana Shi,Kaiyue Sun,Zedi Zhang,Juan Zhao,Lina Geng,Yuhua Lei 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.101 No.-
Carbon dot (CDs) were prepared for carrying DOX (Doxorubicin) or FAC (Ferric ammonium citrate), andthe loading mechanism and release kinetics of CDs-drugs were studied. CDs were prepared using peonypollen and urea, and characterized by TEM, XRD, 13C NMR, XPS, UV, FT-IR, DLS and zeta potential. Theobtained CDs were rich of –NH2 group on the surface, amorphous phase, spherical morphology withthe diameter about 5 nm, and had a blue fluorescence with the quantum yield (QY) of 12%. Iron disorderscan cause cancer or anemia. DOX is used for treating cancer, but has severe side effects. FAC is an ironsupplement agent, but had low bioavailability. CDs carried DOX (or FAC) through –N=C– (or –CONH–)bond, had high loading efficiency for DOX (37.2%) and FAC (54.0%) by optimizing mass ratios of mCDsto mdrug and reacted overnight. Cellular experiments showed that CDs-drugs had lower cytotoxicity thanfree drugs and CDs co-located with the drug. In vitro release indicated that CDs-DOX had pH-targetedproperty and CDs-FAC could be absorbed easily. CDs-drug release belonged to Weibull model, and releasemechanism was determined by the bonding way between CDs and drug. CDs had potential applicationsin delivery drugs with –C=O or –COOH group.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
